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7YFQ
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BU of 7yfq by Molmil
Cryo-EM structure of the EfPiwi (N959K)-piRNA-target ternary complex
Descriptor: MAGNESIUM ION, Piwi, RNA (5'-R(*UP*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*AP*A)-3'), ...
Authors:Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z.
Deposit date:2022-07-08
Release date:2024-02-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
6EY5
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BU of 6ey5 by Molmil
C-terminal part (residues 224-515) of PorM
Descriptor: T9SS component cytoplasmic membrane protein PorM, ZINC ION
Authors:Leone, P, Cambillau, C, Roussel, A.
Deposit date:2017-11-10
Release date:2018-02-07
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Type IX secretion system PorM and gliding machinery GldM form arches spanning the periplasmic space.
Nat Commun, 9, 2018
7X0V
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BU of 7x0v by Molmil
cryo-EM structure of human TRiC-ADP-AlFx
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ...
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-02-22
Release date:2023-04-12
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
5NME
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BU of 5nme by Molmil
868 TCR in complex with HLA A02 presenting SLYNTVATL
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2017-04-05
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017
6HQV
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BU of 6hqv by Molmil
Pentafunctional AROM Complex from Chaetomium thermophilum
Descriptor: (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, (4S,5R)-4,5-dihydroxy-3-oxocyclohex-1-ene-1-carboxylic acid, GLUTAMIC ACID, ...
Authors:Arora Verasto, H, Hartmann, M.D.
Deposit date:2018-09-25
Release date:2020-05-06
Last modified:2020-08-26
Method:X-RAY DIFFRACTION (3 Å)
Cite:Architecture and functional dynamics of the pentafunctional AROM complex.
Nat.Chem.Biol., 16, 2020
1GRN
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BU of 1grn by Molmil
CRYSTAL STRUCTURE OF THE CDC42/CDC42GAP/ALF3 COMPLEX.
Descriptor: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Nassar, N, Hoffman, G.R, Clardy, J.C, Cerione, R.A.
Deposit date:1998-07-30
Release date:1999-12-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP.
Nat.Struct.Biol., 5, 1998
7X0S
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BU of 7x0s by Molmil
Human TRiC-tubulin-S3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ...
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-02-22
Release date:2023-04-12
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
6USO
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BU of 6uso by Molmil
Telomerase Reverse Transcriptase prenucleotide binary complex, TERT:DNA
Descriptor: DNA (5'-D(*GP*GP*TP*CP*AP*GP*GP*TP*CP*AP*GP*GP*TP*CP*A)-3'), DNA/RNA (5'-R(*CP*UP*GP*AP*CP*CP*UP*GP*AP*C)-D(P*CP*T)-R(P*GP*AP*C)-D(P*C)-3'), MAGNESIUM ION, ...
Authors:Schaich, M.A, Freudenthal, B.D.
Deposit date:2019-10-28
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Mechanisms of nucleotide selection by telomerase.
Elife, 9, 2020
7X0A
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BU of 7x0a by Molmil
Cryo-EM structure of human TRiC-NPP state
Descriptor: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-02-21
Release date:2023-04-12
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
5NMH
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BU of 5nmh by Molmil
HLA A02 presenting SLYNTIATL
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2017-04-05
Release date:2017-11-15
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Front Immunol, 8, 2017
1QNT
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BU of 1qnt by Molmil
X-ray structure of human O6alkylguanine-DNA alkyltransferase
Descriptor: METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE
Authors:Wibley, J.E.A, Moody, P.C.E.
Deposit date:1999-10-20
Release date:1999-12-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the Human O(6)-Alkylguanine-DNA Alkyltransferase.
Nucleic Acids Res., 28, 2000
5NNB
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BU of 5nnb by Molmil
Isatin hydrolase A (IHA) from Labrenzia aggregata with isatinate bound
Descriptor: Isatinic acid, MANGANESE (II) ION, isatin hydrolase A
Authors:Sommer, T, Bjerregaard-Andersen, K, Morth, J.P.
Deposit date:2017-04-08
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A fundamental catalytic difference between zinc and manganese dependent enzymes revealed in a bacterial isatin hydrolase.
Sci Rep, 8, 2018
1HEJ
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BU of 1hej by Molmil
C-terminal xylan binding domain from Cellulomonas fimi xylanase 11A
Descriptor: ENDO-1,4-BETA-XYLANASE D
Authors:Simpson, P.J, Hefang, X, Bolam, D.N, White, P, Hancock, S.M, Gilbert, H.J, Williamson, M.P.
Deposit date:2000-11-22
Release date:2001-05-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Evidence for Synergy between Family 2B Carbohydrate Binding Modules in Cellulomonas Fimi Xylanase 11A
Biochemistry, 40, 2001
1NPM
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BU of 1npm by Molmil
NEUROPSIN, A SERINE PROTEASE EXPRESSED IN THE LIMBIC SYSTEM OF MOUSE BRAIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, NEUROPSIN
Authors:Kishi, T, Kato, M, Shimizu, T, Kato, K, Matsumoto, K, Yoshida, S, Shiosaka, S, Hakoshima, T.
Deposit date:1998-01-07
Release date:1999-03-23
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of neuropsin, a hippocampal protease involved in kindling epileptogenesis.
J.Biol.Chem., 274, 1999
1HFO
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BU of 1hfo by Molmil
The Structure of the Macrophage Migration Inhibitory Factor from Trichinella Spiralis.
Descriptor: MIGRATION INHIBITORY FACTOR
Authors:Roe, S.M, Meyer, D.J.
Deposit date:2000-12-07
Release date:2001-08-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Macrophage Migration Inhibitory Factor of the Parasitic Nematode Trichinella Spiralis
Biochem.J., 357, 2001
1HDO
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BU of 1hdo by Molmil
Human biliverdin IX beta reductase: NADP complex
Descriptor: BILIVERDIN IX BETA REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Pereira, P.J.B, Macedo-Ribeiro, S, Parraga, A, Perez-Luque, R, Cunningham, O, Darcy, K, Mantle, T.J, Coll, M.
Deposit date:2000-11-16
Release date:2001-02-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Structure of Human Biliverdin Ix Beta Reductase, an Early Fetal Bilirubin Ix Producing Enzyme
Nat.Struct.Biol., 8, 2001
6I0P
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BU of 6i0p by Molmil
Structure of quinolinate synthase in complex with 6-mercaptopyridine-2,3-dicarboxylic acid
Descriptor: 6-mercaptopyridine-2,3-dicarboxylic acid, CHLORIDE ION, IRON/SULFUR CLUSTER, ...
Authors:Volbeda, A, Fontecilla-Camps, J.C.
Deposit date:2018-10-26
Release date:2019-03-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design of specific inhibitors of quinolinate synthase based on [4Fe-4S] cluster coordination.
Chem.Commun.(Camb.), 55, 2019
5NBC
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BU of 5nbc by Molmil
Structure of Prokaryotic Transcription Factors
Descriptor: Ferric uptake regulation protein, MANGANESE (II) ION, ZINC ION
Authors:Perard, J, Carpentier, P, Michaud-Soret, I, Cavazza, C.
Deposit date:2017-03-01
Release date:2018-05-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.699 Å)
Cite:Structural and functional studies of the metalloregulator Fur identify a promoter-binding mechanism and its role inFrancisella tularensisvirulence.
Commun Biol, 1, 2018
5NLI
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BU of 5nli by Molmil
Crystal structure of Zn2-E16V human ubiquitin (hUb) mutant adduct, from a solution 35 mM zinc acetate/10% v/v TFE/1.3 mM E16V hUb
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Polyubiquitin-C, ...
Authors:Fermani, S, Falini, G.
Deposit date:2017-04-04
Release date:2017-05-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Aggregation Pathways of Native-Like Ubiquitin Promoted by Single-Point Mutation, Metal Ion Concentration, and Dielectric Constant of the Medium.
Chemistry, 24, 2018
1HFH
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BU of 1hfh by Molmil
SOLUTION STRUCTURE OF A PAIR OF COMPLEMENT MODULES BY NUCLEAR MAGNETIC RESONANCE
Descriptor: FACTOR H, 15TH AND 16TH C-MODULE PAIR
Authors:Barlow, P.N, Steinkasserer, A, Norman, D.G, Kieffer, B, Wiles, A.P, Sim, R.B, Campbell, I.D.
Deposit date:1993-02-23
Release date:1993-07-15
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of a pair of complement modules by nuclear magnetic resonance.
J.Mol.Biol., 232, 1993
1GOL
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BU of 1gol by Molmil
COORDINATES OF RAT MAP KINASE ERK2 WITH AN ARGININE MUTATION AT POSITION 52
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, EXTRACELLULAR REGULATED KINASE 2, MAGNESIUM ION
Authors:Harkins, P.C, Zhang, F, Goldsmith, E.J.
Deposit date:1996-01-23
Release date:1997-03-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mutation of position 52 in ERK2 creates a nonproductive binding mode for adenosine 5'-triphosphate.
Biochemistry, 35, 1996
1HCT
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BU of 1hct by Molmil
NMR STRUCTURE OF THE HUMAN SRC SH2 DOMAIN COMPLEX
Descriptor: ACETYL-PYEEIE-OH, HUMAN SRC
Authors:Gampe Junior, R.T, Xu, R.X.
Deposit date:1994-09-02
Release date:1995-09-15
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of the human pp60c-src SH2 domain complexed with a phosphorylated tyrosine pentapeptide.
Biochemistry, 34, 1995
1HCS
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BU of 1hcs by Molmil
NMR STRUCTURE OF THE HUMAN SRC SH2 DOMAIN COMPLEX
Descriptor: ACETYL-PYEEIE-OH, HUMAN SRC
Authors:Gampe Junior, R.T, Xu, R.X.
Deposit date:1994-09-02
Release date:1995-09-15
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of the human pp60c-src SH2 domain complexed with a phosphorylated tyrosine pentapeptide.
Biochemistry, 34, 1995
1HFI
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BU of 1hfi by Molmil
SOLUTION STRUCTURE OF A PAIR OF COMPLEMENT MODULES BY NUCLEAR MAGNETIC RESONANCE
Descriptor: FACTOR H, 15TH C-MODULE PAIR
Authors:Barlow, P.N, Steinkasserer, A, Norman, D.G, Kieffer, B, Wiles, A.P, Sim, R.B, Campbell, I.D.
Deposit date:1993-02-23
Release date:1993-07-15
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of a pair of complement modules by nuclear magnetic resonance.
J.Mol.Biol., 232, 1993
1HHO
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BU of 1hho by Molmil
STRUCTURE OF HUMAN OXYHAEMOGLOBIN AT 2.1 ANGSTROMS RESOLUTION
Descriptor: HEMOGLOBIN A (OXY) (ALPHA CHAIN), HEMOGLOBIN A (OXY) (BETA CHAIN), OXYGEN MOLECULE, ...
Authors:Shaanan, B.
Deposit date:1983-06-10
Release date:1983-10-27
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of human oxyhaemoglobin at 2.1 A resolution.
J.Mol.Biol., 171, 1983

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