8QLJ
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![BU of 8qlj by Molmil](/molmil-images/mine/8qlj) | Crystal structure of the pneumococcal Substrate-binding protein AliB in complex with an unknown peptide | Descriptor: | ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, Oligopeptide-binding protein AliB | Authors: | Alcorlo, M, Abdullah, M.R, Hammerschmidt, S, Hermoso, J. | Deposit date: | 2023-09-20 | Release date: | 2024-05-22 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Molecular and structural basis of oligopeptide recognition by the Ami transporter system in pneumococci. Plos Pathog., 20, 2024
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8Q4A
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![BU of 8q4a by Molmil](/molmil-images/mine/8q4a) | Outward-facing, open1 proteoliposome complex I at 2.6 A. Initially purified in LMNG. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Grba, D.N, Hirst, J. | Deposit date: | 2023-08-05 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
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3NLO
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![BU of 3nlo by Molmil](/molmil-images/mine/3nlo) | Structure of neuronal nitric oxide synthase R349A mutant heme domain in complex with 6-{{(3'S,4'R)-3'-[2"-(3'''-fluorophenethylamino)ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine | Descriptor: | 1,2-ETHANEDIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, 6-{[(3R,4S)-4-(2-{[2-(3-fluorophenyl)ethyl]amino}ethoxy)pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine, ... | Authors: | Li, H, Delker, S.L, Poulos, T.L. | Deposit date: | 2010-06-21 | Release date: | 2010-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Exploration of the Active Site of Neuronal Nitric Oxide Synthase by the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine Derivatives. J.Med.Chem., 53, 2010
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1YJI
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![BU of 1yji by Molmil](/molmil-images/mine/1yji) | RDC-refined Solution NMR structure of reduced putidaredoxin | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, Putidaredoxin | Authors: | Jain, N.U, Tjioe, E, Savidor, A, Boulie, J. | Deposit date: | 2005-01-14 | Release date: | 2005-06-28 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Redox-dependent structural differences in putidaredoxin derived from homologous structure refinement via residual dipolar couplings. Biochemistry, 44, 2005
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1YJJ
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![BU of 1yjj by Molmil](/molmil-images/mine/1yjj) | RDC-refined Solution NMR structure of oxidized putidaredoxin | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, Putidaredoxin | Authors: | Jain, N.U, Tjioe, E, Savidor, A, Boulie, J. | Deposit date: | 2005-01-14 | Release date: | 2005-06-28 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Redox-dependent structural differences in putidaredoxin derived from homologous structure refinement via residual dipolar couplings. Biochemistry, 44, 2005
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1YK1
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![BU of 1yk1 by Molmil](/molmil-images/mine/1yk1) | structure of natriuretic peptide receptor-C complexed with brain natriuretic peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Atrial natriuretic peptide clearance receptor, ... | Authors: | He, X, Garcia, K.C. | Deposit date: | 2005-01-16 | Release date: | 2006-04-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural determinants of natriuretic peptide receptor specificity and degeneracy. J.Mol.Biol., 361, 2006
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3NQS
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![BU of 3nqs by Molmil](/molmil-images/mine/3nqs) | Crystal Structure of Inducible Nitric Oxide Synthase with N-Nitrosated-pterin | Descriptor: | 1,2-ETHANEDIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE, ... | Authors: | Rosenfeld, R.J, Getzoff, E.D, Tainer, J.A. | Deposit date: | 2010-06-29 | Release date: | 2010-07-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Nitric-oxide synthase forms N-NO-pterin and S-NO-cys: implications for activity, allostery, and regulation. J.Biol.Chem., 285, 2010
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2VNF
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![BU of 2vnf by Molmil](/molmil-images/mine/2vnf) | MOLECULAR BASIS OF HISTONE H3K4ME3 RECOGNITION BY ING4 | Descriptor: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, HISTONE H3, ... | Authors: | Palacios, A, Munoz, I.G, Pantoja-Uceda, D, Marcaida, M.J, Torres, D, Martin-Garcia, J.M, Luque, I, Montoya, G, Blanco, F.J. | Deposit date: | 2008-02-04 | Release date: | 2008-04-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Molecular Basis of Histone H3K4Me3 Recognition by Ing4 J.Biol.Chem., 283, 2008
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2VCE
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![BU of 2vce by Molmil](/molmil-images/mine/2vce) | Characterization and engineering of the bifunctional N- and O- glucosyltransferase involved in xenobiotic metabolism in plants | Descriptor: | 1,2-ETHANEDIOL, 2,4,5-trichlorophenol, HYDROQUINONE GLUCOSYLTRANSFERASE, ... | Authors: | Brazier-Hicks, M, Offen, W.A, Gershater, M.C, Revett, T.J, Lim, E.K, Bowles, D.J, Davies, G.J, Edwards, R. | Deposit date: | 2007-09-20 | Release date: | 2007-10-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Characterization and Engineering of the Bifunctional N- and O-Glucosyltransferase Involved in Xenobiotic Metabolism in Plants. Proc.Natl.Acad.Sci.USA, 104, 2007
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1YNX
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8PVD
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![BU of 8pvd by Molmil](/molmil-images/mine/8pvd) | Structure of catalase determined by cryoEM at 100 keV | Descriptor: | Catalase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | McMullan, G, Naydenova, K, Mihaylov, D, Peet, M.J, Wilson, H, Yamashita, K, Dickerson, J.L, Chen, S, Cannone, G, Lee, Y, Hutchings, K.A, Gittins, O, Sobhy, M, Wells, T, El-Gomati, M.M, Dalby, J, Meffert, M, Schulze-Briese, C, Henderson, R, Russo, C.J. | Deposit date: | 2023-07-17 | Release date: | 2023-11-29 | Last modified: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure determination by cryoEM at 100 keV. Proc.Natl.Acad.Sci.USA, 120, 2023
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2Y7Z
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![BU of 2y7z by Molmil](/molmil-images/mine/2y7z) | Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine P4 motifs | Descriptor: | 6-CHLORO-N-[(3S)-1-[(1S)-1-DIMETHYLAMINO-2,3-DIHYDRO-1H-INDEN-5-YL]-2-OXO-PYRROLIDIN-3-YL]NAPHTHALENE-2-SULFONAMIDE, ACTIVATED FACTOR XA HEAVY CHAIN, CALCIUM ION, ... | Authors: | Young, R.J, Adams, C, Blows, M, Brown, D, Burns-Kurtis, C.L, Chaudry, L, Chan, C, Convery, M.A, Davies, D.E, Exall, A.M, Foster, G, Harling, J.D, Hortense, E, Irving, W.R, Irvine, S, Jackson, S, Kleanthous, S, Pateman, A.J, Patikis, A.N, Roethka, T.J, Senger, S, Stelman, G.J, Toomey, J.R, West, R.I, Whittaker, C, Zhou, P, Watson, N.S. | Deposit date: | 2011-02-02 | Release date: | 2011-03-16 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Aminoindane and Phenylpyrrolidine P4 Motifs. Bioorg.Med.Chem.Lett., 21, 2011
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2VCP
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![BU of 2vcp by Molmil](/molmil-images/mine/2vcp) | Crystal structure of N-Wasp VC domain in complex with skeletal actin | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Gaucher, J.F, Didry, D, Carlier, M.F. | Deposit date: | 2007-09-26 | Release date: | 2008-11-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Interactions of isolated C-terminal fragments of neural Wiskott-Aldrich syndrome protein (N-WASP) with actin and Arp2/3 complex. J. Biol. Chem., 287, 2012
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8Q2W
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![BU of 8q2w by Molmil](/molmil-images/mine/8q2w) | |
8Q2Q
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![BU of 8q2q by Molmil](/molmil-images/mine/8q2q) | Crystal structure of YTHDC1 in complex with Compound 2b (YL_32) | Descriptor: | 2-chloranyl-~{N},9-dimethyl-purin-6-amine, SULFATE ION, YTH domain-containing protein 1 | Authors: | Bedi, R.K, Li, Y, Caflisch, A. | Deposit date: | 2023-08-03 | Release date: | 2023-12-06 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure-Based Design of a Potent and Selective YTHDC1 Ligand. J.Med.Chem., 67, 2024
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8Q32
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2VM9
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![BU of 2vm9 by Molmil](/molmil-images/mine/2vm9) | Native structure of the recombinant discoidin II of Dictyostelium discoideum at 1.75 angstrom | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Aragao, K.S, Satre, M, Imberty, A, Varrot, A. | Deposit date: | 2008-01-24 | Release date: | 2008-07-01 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure Determination of Discoidin II from Dictyostelium Discoideum and Carbohydrate Binding Properties of the Lectin Domain. Proteins, 73, 2008
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8Q4U
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2VIG
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![BU of 2vig by Molmil](/molmil-images/mine/2vig) | Crystal structure of human short-chain acyl CoA dehydrogenase | Descriptor: | 1,2-ETHANEDIOL, COENZYME A PERSULFIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Pike, A.C.W, Pantic, N, Parizotto, E, Gileadi, O, Ugochukwu, E, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A, Oppermann, U. | Deposit date: | 2007-11-30 | Release date: | 2007-12-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of Human Short-Chain Acyl Coa Dehydrogenase To be Published
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8Q38
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![BU of 8q38 by Molmil](/molmil-images/mine/8q38) | |
8Q4Q
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![BU of 8q4q by Molmil](/molmil-images/mine/8q4q) | |
8Q2T
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![BU of 8q2t by Molmil](/molmil-images/mine/8q2t) | |
8Q33
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![BU of 8q33 by Molmil](/molmil-images/mine/8q33) | Crystal structure of YTHDC1 in complex with Compound 15 (ZA_343) | Descriptor: | SULFATE ION, YTH domain-containing protein 1, ~{N}-[2-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]phenyl]-2,2,2-tris(fluoranyl)ethanamide | Authors: | Bedi, R.K, Zalesak, F, Caflisch, A. | Deposit date: | 2023-08-03 | Release date: | 2023-12-06 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Structure-Based Design of a Potent and Selective YTHDC1 Ligand. J.Med.Chem., 67, 2024
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2YE0
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![BU of 2ye0 by Molmil](/molmil-images/mine/2ye0) | X-ray structure of the cyan fluorescent protein mTurquoise (K206A mutant) | Descriptor: | GREEN FLUORESCENT PROTEIN | Authors: | von Stetten, D, Goedhart, J, Noirclerc-Savoye, M, Lelimousin, M, Joosen, L, Hink, M.A, van Weeren, L, Gadella, T.W.J, Royant, A. | Deposit date: | 2011-03-25 | Release date: | 2012-03-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Structure-Guided Evolution of Cyan Fluorescent Proteins Towards a Quantum Yield of 93% Nat.Commun, 3, 2012
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8Q4R
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![BU of 8q4r by Molmil](/molmil-images/mine/8q4r) | |