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5UWQ
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BU of 5uwq by Molmil
Crystal Structure of CDC7 NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Cell division cycle 7-related protein kinase, Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.278 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
1GAD
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BU of 1gad by Molmil
COMPARISON OF THE STRUCTURES OF WILD TYPE AND A N313T MUTANT OF ESCHERICHIA COLI GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASES: IMPLICATION FOR NAD BINDING AND COOPERATIVITY
Descriptor: D-GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Duee, E, Olivier-Deyris, L, Fanchon, E, Corbier, C, Branlant, G, Dideberg, O.
Deposit date:1995-10-24
Release date:1996-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Comparison of the structures of wild-type and a N313T mutant of Escherichia coli glyceraldehyde 3-phosphate dehydrogenases: implication for NAD binding and cooperativity.
J.Mol.Biol., 257, 1996
3BO1
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BU of 3bo1 by Molmil
Ribosome-SecY complex
Descriptor: 23S RIBOSOMAL RNA, PREPROTEIN TRANSLOCASE SecE SUBUNIT, PREPROTEIN TRANSLOCASE SecY SUBUNIT, ...
Authors:Akey, C.W, Menetret, J.F.
Deposit date:2007-12-15
Release date:2008-12-09
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (9.6 Å)
Cite:Ribosome binding of a single copy of the SecY complex: implications for protein translocation
Mol.Cell, 28, 2007
5TLJ
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BU of 5tlj by Molmil
COMPLEX BETWEEN HUMAN CD27 AND FAB FRAGMENTS OF ANTIBODIES M2177 AND M2191
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD27 antigen, M2177 HEAVY CHAIN, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2016-10-11
Release date:2017-02-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Epitope-dependent mechanisms of CD27 neutralization revealed by X-ray crystallography.
Mol. Immunol., 83, 2017
5T6R
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BU of 5t6r by Molmil
Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis: 60S-Nmd3 Complex
Descriptor: 25S Ribosomal RNA, 5.8S Ribosomal RNA, 5S Ribosomal RNA, ...
Authors:Malyutin, A.G, Musalgaonkar, S, Patchett, S, Frank, J, Johnson, A.W.
Deposit date:2016-09-01
Release date:2017-02-08
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis.
EMBO J., 36, 2017
3HSG
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BU of 3hsg by Molmil
Crystal structure of E. coli HPPK(Y53A) in complex with MgAMPCPP
Descriptor: ACETATE ION, CHLORIDE ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
Authors:Blaszczyk, J, Li, Y, Yan, H, Ji, X.
Deposit date:2009-06-10
Release date:2010-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK
To be Published
7EJO
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BU of 7ejo by Molmil
Structure of ERH-2 bound to TOST-1
Descriptor: Enhancer of rudimentary homolog 2, Enhancer of rudimentary homolog 2,Protein tost-1
Authors:Wang, X, Xu, C.
Deposit date:2021-04-02
Release date:2021-08-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.191 Å)
Cite:Molecular basis for PICS-mediated piRNA biogenesis and cell division.
Nat Commun, 12, 2021
5TFX
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BU of 5tfx by Molmil
New method for synthesis of benzoxazole amide inhibitors of carbonic anhydrase
Descriptor: Carbonic anhydrase 2, GLYCEROL, N-(5-sulfamoyl-1,3-benzoxazol-2-yl)benzamide, ...
Authors:Peat, T.S, Supuran, C.
Deposit date:2016-09-26
Release date:2017-08-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Intramolecular oxidative deselenization of acylselenoureas: a facile synthesis of benzoxazole amides and carbonic anhydrase inhibitors.
Org. Biomol. Chem., 14, 2016
5UWT
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BU of 5uwt by Molmil
Crystal Structure of Hxk2 Peptide in complex with CRM1 K579A mutant-Ran-RanBP1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.342 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWS
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BU of 5uws by Molmil
Crystal Structure of X11L2 NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Amyloid beta A4 precursor protein-binding family A member 3, Exportin-1,Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5DJR
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BU of 5djr by Molmil
Crystal structure of human FPPS in complex with biaryl compound 6
Descriptor: 1H,1'H-4,4'-biindole-2-carboxylic acid, Farnesyl pyrophosphate synthase, GLYCEROL, ...
Authors:Rondeau, J.M, Bourgier, E, Lehmann, S.
Deposit date:2015-09-02
Release date:2015-09-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
Chemmedchem, 10, 2015
5UQX
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BU of 5uqx by Molmil
USP7 in complex with GNE6776 (6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide)
Descriptor: 6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl[3,3'-bipyridine]-6-carboxamide, Ubiquitin carboxyl-terminal hydrolase 7
Authors:Murray, J.M, Rouge, L.
Deposit date:2017-02-08
Release date:2017-10-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:USP7 small-molecule inhibitors interfere with ubiquitin binding.
Nature, 550, 2017
1APY
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BU of 1apy by Molmil
HUMAN ASPARTYLGLUCOSAMINIDASE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ASPARTYLGLUCOSAMINIDASE, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Rouvinen, J, Oinonen, C.
Deposit date:1995-06-14
Release date:1996-12-23
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structure of human lysosomal aspartylglucosaminidase.
Nat.Struct.Biol., 2, 1995
1TMT
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BU of 1tmt by Molmil
CHANGES IN INTERACTIONS IN COMPLEXES OF HIRUDIN DERIVATIVES AND HUMAN ALPHA-THROMBIN DUE TO DIFFERENT CRYSTAL FORMS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ...
Authors:Priestle, J.P, Gruetter, M.G.
Deposit date:1994-05-26
Release date:1994-09-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Changes in interactions in complexes of hirudin derivatives and human alpha-thrombin due to different crystal forms.
Protein Sci., 2, 1993
6TIQ
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BU of 6tiq by Molmil
Refined solution NMR structure of hVDAC-1 in detergent micelles
Descriptor: Voltage-dependent anion-selective channel protein 1
Authors:Boehm, R, Hiller, S, Wagner, G.
Deposit date:2019-11-22
Release date:2019-12-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The Structural Basis for Low Conductance in the Membrane Protein VDAC upon beta-NADH Binding and Voltage Gating.
Structure, 28, 2020
3SR6
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BU of 3sr6 by Molmil
Crystal Structure of Reduced Bovine Xanthine Oxidase in Complex with Arsenite
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER, ...
Authors:Cao, H, Hille, R.
Deposit date:2011-07-07
Release date:2011-07-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray Crystal Structure of Arsenite-Inhibited Xanthine Oxidase: Mu-Sulfido,Mu-Oxo Double Bridge between Molybdenum and Arsenic in the Active Site.
J.Am.Chem.Soc., 133, 2011
5VM9
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BU of 5vm9 by Molmil
Human Argonaute3 bound to guide RNA
Descriptor: Protein argonaute-3, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*UP*U)-3'), RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*UP*U)-3')
Authors:Park, M.S, Nakanishi, K.
Deposit date:2017-04-26
Release date:2017-10-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Human Argonaute3 has slicer activity.
Nucleic Acids Res., 45, 2017
5B24
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BU of 5b24 by Molmil
The crystal structure of the nucleosome containing cyclobutane pyrimidine dimer
Descriptor: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Horikoshi, N, Tachiwana, H, Kagawa, W, Osakabe, A, Kurumizaka, H.
Deposit date:2015-12-31
Release date:2016-03-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Crystal structure of the nucleosome containing ultraviolet light-induced cyclobutane pyrimidine dimer
Biochem.Biophys.Res.Commun., 471, 2016
1KIX
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BU of 1kix by Molmil
Dimeric Structure of the O. nova Telomere End Binding Protein Alpha Subunit with Bound ssDNA
Descriptor: 5'-D(*T*TP*TP*TP*GP*GP*GP*G)-3', SULFATE ION, Telomere-Binding Protein alpha Subunit
Authors:Peersen, O.B, Ruggles, J.A, Schultz, S.C.
Deposit date:2001-12-03
Release date:2002-02-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Dimeric structure of the Oxytricha nova telomere end-binding protein alpha-subunit bound to ssDNA.
Nat.Struct.Biol., 9, 2002
3AT1
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BU of 3at1 by Molmil
CRYSTAL STRUCTURES OF PHOSPHONOACETAMIDE LIGATED T AND PHOSPHONOACETAMIDE AND MALONATE LIGATED R STATES OF ASPARTATE CARBAMOYLTRANSFERASE AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL PH
Descriptor: ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
Authors:Gouaux, J.E, Lipscomb, W.N.
Deposit date:1989-09-22
Release date:1990-10-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of phosphonoacetamide ligated T and phosphonoacetamide and malonate ligated R states of aspartate carbamoyltransferase at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
5UBD
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BU of 5ubd by Molmil
Crystal structure of the N-terminal domain (domain 1) of RctB, RctB-1-124-L48M
Descriptor: RctB replication initiator protein
Authors:Orlova, N, Ivashkiv, O, Waldor, M.K, Jeruzalmi, D.
Deposit date:2016-12-20
Release date:2017-01-11
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:The replication initiator of the cholera pathogen's second chromosome shows structural similarity to plasmid initiators.
Nucleic Acids Res., 45, 2017
5DRM
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BU of 5drm by Molmil
Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a dichloro-substituted, 2,5-diarylthiophene-core ligand 4,4'-thiene-2,5-diylbis(3-chlorophenol)
Descriptor: 4,4'-thiene-2,5-diylbis(3-chlorophenol), Estrogen receptor, Nuclear receptor coactivator 2
Authors:Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
Deposit date:2015-09-16
Release date:2016-05-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.241 Å)
Cite:Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
5UWP
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BU of 5uwp by Molmil
Crystal Structure of mDia2 NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.054 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWO
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BU of 5uwo by Molmil
Crystal Structure of Engineered FMRP-1b NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Engineered FMRP-1b peptide, Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.347 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWH
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BU of 5uwh by Molmil
Crystal Structure of Paxillin NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017

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