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2H6B
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BU of 2h6b by Molmil
Crystal structure of oxidized CprK in complex with o-chlorophenolacetic acid
Descriptor: (3-CHLORO-4-HYDROXYPHENYL)ACETIC ACID, ChloroPhenol Reduction gene K, SULFATE ION
Authors:Joyce, M.G, Levy, C, Leys, D.
Deposit date:2006-05-31
Release date:2006-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:CprK Crystal Structures Reveal Mechanism for Transcriptional Control of Halorespiration.
J.Biol.Chem., 281, 2006
2H6C
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BU of 2h6c by Molmil
Crystal structure of reduced CprK in absence of any ligand
Descriptor: ChloroPhenol Reduction gene K
Authors:Levy, C, Leys, D.
Deposit date:2006-05-31
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:CprK Crystal Structures Reveal Mechanism for Transcriptional Control of Halorespiration.
J.Biol.Chem., 281, 2006
7CAL
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BU of 7cal by Molmil
Cryo-EM Structure of the Hyperpolarization-Activated Inwardly Rectifying Potassium Channel KAT1 from Arabidopsis
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Potassium channel KAT1
Authors:Li, S.Y, Yang, F, Sun, D.M, Zhang, Y, Zhang, M.G, Zhou, P, Liu, S.L, Zhang, Y.N, Zhang, L.H, Tian, C.L.
Deposit date:2020-06-09
Release date:2020-07-29
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the hyperpolarization-activated inwardly rectifying potassium channel KAT1 from Arabidopsis.
Cell Res., 30, 2020
7T4W
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BU of 7t4w by Molmil
Crystal Structure of cGMP-dependent Protein Kinase
Descriptor: (2R)-2-({(2S,3S)-1-[(1H-benzimidazol-2-yl)methyl]-2-phenylpiperidin-3-yl}oxy)-2-(3,5-dichlorophenyl)ethan-1-ol, CHLORIDE ION, cGMP-dependent protein kinase 1
Authors:Zebisch, M, Silvestre, L, Fischmann, T.O.
Deposit date:2021-12-10
Release date:2023-06-14
Last modified:2023-07-12
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Selective small molecule activation of PKG1alpha: structure and function
Commun Biol, 2023
7T4V
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BU of 7t4v by Molmil
Crystal Structure of cGMP-dependent Protein Kinase
Descriptor: 4-({(2S,3S)-3-[(1S)-1-(3,5-dichlorophenyl)-2-hydroxyethoxy]-2-phenylpiperidin-1-yl}methyl)-3-methylbenzoic acid, CHLORIDE ION, cGMP-dependent protein kinase 1
Authors:Zebisch, M, Silvestre, L, Fischmann, T.O.
Deposit date:2021-12-10
Release date:2023-06-14
Last modified:2023-07-12
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Selective small molecule activation of PKG1alpha: structure and function
Commun Biol, 2023
7T4U
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BU of 7t4u by Molmil
Crystal Structure of cGMP-dependent Protein Kinase
Descriptor: 3-amino-4-({(2S,3S)-3-[(1S)-1-(3,5-dichlorophenyl)-2-hydroxyethoxy]-2-phenylpiperidin-1-yl}methyl)benzoic acid, cGMP-dependent protein kinase 1
Authors:Zebisch, M, Silvestre, L, Fischmann, T.O.
Deposit date:2021-12-10
Release date:2023-06-14
Last modified:2023-07-12
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Selective small molecule activation of PKG1alpha: structure and function
Commun Biol, 2023
7T4T
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BU of 7t4t by Molmil
Crystal Structure of cGMP-dependent Protein Kinase
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
Authors:Zebisch, M, Silvestre, L, Fischmann, T.O.
Deposit date:2021-12-10
Release date:2023-06-14
Last modified:2023-07-12
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Selective small molecule activation of PKG1alpha: structure and function
Commun Biol, 2023
7TKT
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BU of 7tkt by Molmil
SthK closed state, cAMP-bound in the presence of detergent
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Putative transcriptional regulator, ...
Authors:Rheinberger, J, Schmidpeter, P.A, Nimigean, C.M.
Deposit date:2022-01-17
Release date:2022-10-26
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Anionic lipids unlock the gates of select ion channels in the pacemaker family.
Nat.Struct.Mol.Biol., 29, 2022
7TJ5
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BU of 7tj5 by Molmil
SthK closed state, cAMP-bound in the presence of POPA
Descriptor: (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Putative transcriptional regulator, ...
Authors:Schmidpeter, P.A, Nimigean, C.M.
Deposit date:2022-01-14
Release date:2022-10-26
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.41 Å)
Cite:Anionic lipids unlock the gates of select ion channels in the pacemaker family.
Nat.Struct.Mol.Biol., 29, 2022
7TJ6
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BU of 7tj6 by Molmil
SthK open state, cAMP-bound in the presence of POPA
Descriptor: (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Putative transcriptional regulator, ...
Authors:Schmidpeter, P.A, Nimigean, C.M.
Deposit date:2022-01-14
Release date:2022-10-26
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Anionic lipids unlock the gates of select ion channels in the pacemaker family.
Nat.Struct.Mol.Biol., 29, 2022
7FF9
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BU of 7ff9 by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and Cl(triethylphosphine)gold(I)
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CHLORIDE ION, GOLD ION, ...
Authors:Chew, B.L.A, Luo, D.
Deposit date:2021-07-23
Release date:2022-07-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Inhibitory mechanism of gold analogues against Pseudomonas global virulence factor regulator Vfr
To Be Published
7FEW
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BU of 7few by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin gold analogues
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cAMP-activated global transcriptional regulator Vfr
Authors:Chew, B.L.A, Luo, D.
Deposit date:2021-07-22
Release date:2022-07-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr.
Comput Struct Biotechnol J, 21, 2023
7ETS
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BU of 7ets by Molmil
Crystal structure of crp protein from Gardnerella Vaginalis
Descriptor: Crp/Fnr family transcriptional regulator, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Dong, H.J, Wang, S, Zhang, J.M, Gu, L.
Deposit date:2021-05-13
Release date:2022-04-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Crystal structure of crp protein from Gardnerella Vaginalis
To Be Published
7FF0
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BU of 7ff0 by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GOLD ION, SULFATE ION, ...
Authors:Chew, B.L.A, Luo, D.
Deposit date:2021-07-22
Release date:2022-07-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the inhibitory mechanism of auranofin and gold(I) analogues against Pseudomonas aeruginosa global virulence factor regulator Vfr.
Comput Struct Biotechnol J, 21, 2023
7FF8
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BU of 7ff8 by Molmil
Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and Cl(triethylphosphine)gold(I)
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CHLORIDE ION, GOLD ION, ...
Authors:Chew, B.L.A, Luo, D.
Deposit date:2021-07-22
Release date:2022-07-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Inhibitory mechanism of gold analogues against Pseudomonas global virulence factor regulator Vfr
To Be Published
5U6O
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BU of 5u6o by Molmil
Structure of the human HCN1 hyperpolarization-activated cyclic nucleotide-gated ion channel
Descriptor: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
Authors:Lee, C.-H, MacKinnon, R.
Deposit date:2016-12-08
Release date:2017-01-25
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structures of the Human HCN1 Hyperpolarization-Activated Channel.
Cell, 168, 2017
5U6P
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BU of 5u6p by Molmil
Structure of the human HCN1 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 11
Authors:Lee, C.-H, MacKinnon, R.
Deposit date:2016-12-08
Release date:2017-01-25
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.51 Å)
Cite:Structures of the Human HCN1 Hyperpolarization-Activated Channel.
Cell, 168, 2017
4OLL
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BU of 4oll by Molmil
cAMP-binding acyltransferase from Mycobacterium smegmatis
Descriptor: Acetyltransferase Pat, CALCIUM ION, MERCURY (II) ION
Authors:Podobnik, M, Rebolj, K, Visweswariah, S.S.
Deposit date:2014-01-24
Release date:2014-04-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Allostery and Conformational Dynamics in cAMP-binding Acyltransferases.
J.Biol.Chem., 289, 2014
4FT8
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BU of 4ft8 by Molmil
E. coli Catabolite Activator Protein with Cobalt and Sulfate Ligands
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, COBALT (II) ION, Catabolite gene activator, ...
Authors:Rao, R, Lawson, C.L.
Deposit date:2012-06-27
Release date:2013-12-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.966 Å)
Cite:Structure of catabolite activator protein with cobalt(II) and sulfate.
Acta Crystallogr F Struct Biol Commun, 70, 2014
6B6H
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BU of 6b6h by Molmil
The cryo-EM structure of a bacterial class I transcription activation complex
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Liu, B, Hong, C, Huang, R, Yu, Z, Steitz, T.A.
Deposit date:2017-10-02
Release date:2017-11-15
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of bacterial transcription activation.
Science, 358, 2017
2ZCW
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BU of 2zcw by Molmil
Crystal Structure of TTHA1359, a Transcriptional Regulator, CRP/FNR family from Thermus thermophilus HB8
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Transcriptional regulator, FNR/CRP family
Authors:Agari, Y, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-11-13
Release date:2007-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Global gene expression mediated by Thermus thermophilus SdrP, a CRP/FNR family transcriptional regulator
Mol.Microbiol., 70, 2008
2ZD9
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BU of 2zd9 by Molmil
Structure of a Bacterial Cyclic-Nucleotide Regulated Ion Channel
Descriptor: Mll3241 protein, POTASSIUM ION
Authors:Clayton, G.M, Cabral-Morais, J.M.
Deposit date:2007-11-21
Release date:2008-12-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel.
Proc.Natl.Acad.Sci.USA, 105, 2008
5VA1
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BU of 5va1 by Molmil
Cryo-EM structure of the human ether-a-go-go related K+ channel
Descriptor: Potassium voltage-gated channel subfamily H member 2
Authors:Wang, W.W, MacKinnon, R.
Deposit date:2017-03-24
Release date:2017-05-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM Structure of the Open Human Ether-a-go-go-Related K(+) Channel hERG.
Cell, 169, 2017
2XGX
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BU of 2xgx by Molmil
Crystal structure of transcription factor NtcA from Synechococcus elongatus (mercury derivative)
Descriptor: 2-OXOGLUTARIC ACID, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLOBAL NITROGEN REGULATOR, ...
Authors:Llacer, J.L, Castells, M.A, Rubio, V.
Deposit date:2010-06-08
Release date:2010-08-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural Basis for the Regulation of Ntca-Dependent Transcription by Proteins Pipx and Pii.
Proc.Natl.Acad.Sci.USA, 107, 2010
5VA3
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BU of 5va3 by Molmil
Cryo-EM structure of the human ether-a-go-go related K+ channel
Descriptor: Potassium voltage-gated channel subfamily H member 2
Authors:Wang, W.W, MacKinnon, R.
Deposit date:2017-03-24
Release date:2017-05-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM Structure of the Open Human Ether-a-go-go-Related K(+) Channel hERG.
Cell, 169, 2017

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