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8DFI
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BU of 8dfi by Molmil
Crystal structure of moderately neutralizing / interfering human monoclonal antibody 42C11 Fab in complex with MSP1-19
Descriptor: 42C11 Fab Heavy Chain, 42C11 Fab Light Chain, Merozoite surface protein 1
Authors:Patel, P.N, Tang, W.K, Tolia, N.H.
Deposit date:2022-06-22
Release date:2022-10-12
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
7RAJ
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BU of 7raj by Molmil
Structure of PfCSP peptide 21 with antibody iGL-CIS43.D3
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP-PRO-ASN-ALA-ASN, ZINC ION, ...
Authors:Tripathi, P, Kwong, P.D.
Deposit date:2021-07-01
Release date:2021-12-15
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Immunity, 54, 2021
3DJ9
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BU of 3dj9 by Molmil
Crystal Structure of an isolated, unglycosylated antibody CH2 domain
Descriptor: Ig gamma-1 chain C region
Authors:Prabakaran, P, Vu, B.K, Gan, J, Dimitrov, D.S, Ji, X.
Deposit date:2008-06-22
Release date:2008-09-16
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of an isolated unglycosylated antibody C(H)2 domain.
Acta Crystallogr.,Sect.D, 64, 2008
7QXC
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BU of 7qxc by Molmil
Recognition of Staphylococcus aureus wall teichoic acid analogue SA533 (compound 1) by Fab4461
Descriptor: (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, DI(HYDROXYETHYL)ETHER, Fab 4461 heavy chain, ...
Authors:Soriano-Maldonado, P, van Raaij, M.J.
Deposit date:2022-01-26
Release date:2022-08-31
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.452 Å)
Cite:Antibody Recognition of Different Staphylococcus aureus Wall Teichoic Acid Glycoforms.
Acs Cent.Sci., 8, 2022
6CBV
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BU of 6cbv by Molmil
Crystal structure of BRIL bound to an affinity matured synthetic antibody.
Descriptor: BRIL, FORMIC ACID, GLYCEROL, ...
Authors:Mukherjee, S, Skrobek, B, Kossiakoff, A.A.
Deposit date:2018-02-05
Release date:2019-02-06
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.872 Å)
Cite:Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
Nat Commun, 11, 2020
2J5L
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BU of 2j5l by Molmil
Structure of a Plasmodium falciparum apical membrane antigen 1-Fab F8. 12.19 complex
Descriptor: APICAL MEMBRANE ANTIGEN 1, FAB FRAGMENT OF MONOCLONAL ANTIBODY F8.12.19
Authors:Igonet, S, Vulliez-Le Normand, B, Faure, G, Riottot, M.M, Kocken, C.H.M, Thomas, A.W, Bentley, G.A.
Deposit date:2006-09-18
Release date:2007-01-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Cross-Reactivity Studies of an Anti-Plasmodium Vivax Apical Membrane Antigen 1 Monoclonal Antibody: Binding and Structural Characterisation.
J.Mol.Biol., 366, 2007
8G4T
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BU of 8g4t by Molmil
Vaccine-elicited human antibody 2C09 in complex with HIV-1 envelope trimer BG505 DS-SOSIP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein BG505 DS-SOSIP gp120, ...
Authors:Wang, S, Kwong, P.D.
Deposit date:2023-02-10
Release date:2023-07-12
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide.
Cell Rep, 42, 2023
5SZF
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BU of 5szf by Molmil
2A10 FAB fragment 2.54 Angstoms
Descriptor: 2A10 antibody FAB fragment heavy chain, 2A10 antibody FAB fragment light chain, SULFATE ION
Authors:Jackson, C.J, Fisher, C.
Deposit date:2016-08-13
Release date:2017-07-26
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:T-dependent B cell responses to Plasmodium induce antibodies that form a high-avidity multivalent complex with the circumsporozoite protein.
PLoS Pathog., 13, 2017
1UM4
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BU of 1um4 by Molmil
Catalytic Antibody 21H3 with hapten
Descriptor: (1R)-1-PHENYLETHYL 4-(ACETYLAMINO)BENZYLPHOSPHONATE, Antibody 21H3 H chain, Antibody 21H3 L chain
Authors:Beuscher IV, A.E, Reuter, J, Olson, A.J, Romesberg, F.E, Schultz, P.G, Wirsching, P, Janda, K.D, Lerner, R.A, Stevens, R.C.
Deposit date:2003-09-23
Release date:2004-10-05
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Studies of an Efficient Catalytic Antibody Operating by Ping-Pong and Induced Fit Mechanisms
To be Published
1UJ3
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BU of 1uj3 by Molmil
Crystal structure of a humanized Fab fragment of anti-tissue-factor antibody in complex with tissue factor
Descriptor: IgG Fab heavy chain, IgG Fab light chain, tissue factor
Authors:Ohto, U, Mizutani, R, Nakamura, M, Adachi, H, Satow, Y.
Deposit date:2003-07-25
Release date:2004-07-25
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a humanized Fab fragment of anti-tissue-factor antibody in complex with tissue factor.
J.Synchrotron Radiat., 11, 2004
6GG0
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BU of 6gg0 by Molmil
Cryo-EM structure of BK polyomavirus like particle in complex with single chain antibody ScFv41F17
Descriptor: Capsid protein VP1, Heavy chain, light chain
Authors:Srinivas, H.
Deposit date:2018-05-02
Release date:2019-03-06
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.24 Å)
Cite:Human Memory B Cells Harbor Diverse Cross-Neutralizing Antibodies against BK and JC Polyomaviruses.
Immunity, 50, 2019
8V2E
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BU of 8v2e by Molmil
Crystal structure of B055 scaffold boost immunogen in complex with a mature 10E8 Fab
Descriptor: 10E8 EPITOPE SCAFFOLD B055, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 10E8 FAB HEAVY CHAIN, ...
Authors:Cho, S.Y, Wilson, I.A.
Deposit date:2023-11-22
Release date:2024-06-12
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
1UM5
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BU of 1um5 by Molmil
Catalytic Antibody 21H3 with alcohol substrate
Descriptor: 1-PHENYLETHANOL, Antibody 21H3 H chain, Antibody 21H3 L chain
Authors:Beuscher IV, A.E, Reuter, J, Olson, A.J, Romesberg, F.E, Schultz, P.G, Wirsching, P, Janda, K.D, Lerner, R.A, Stevens, R.C.
Deposit date:2003-09-23
Release date:2004-10-05
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Studies of an Efficient Catalytic Antibody Operating by Ping-Pong and Induced Fit Mechanisms
To be Published
5TH6
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BU of 5th6 by Molmil
Structure determination of a potent, selective antibody inhibitor of human MMP9 (apo MMP9)
Descriptor: CALCIUM ION, Matrix metalloproteinase-9,Matrix metalloproteinase-9, ZINC ION
Authors:Appleby, T.C, Greenstein, A.E, Kwon, H.J.
Deposit date:2016-09-29
Release date:2017-03-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Biochemical characterization and structure determination of a potent, selective antibody inhibitor of human MMP9.
J. Biol. Chem., 292, 2017
5TH9
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BU of 5th9 by Molmil
Structure determination of a potent, selective antibody inhibitor of human MMP9 (GS-5745 bound to MMP-9)
Descriptor: CALCIUM ION, COBALT HEXAMMINE(III), GS-5745 Fab heavy chain, ...
Authors:Appleby, T.C, Greenstein, A.E, Kwon, H.J.
Deposit date:2016-09-29
Release date:2017-03-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.999 Å)
Cite:Biochemical characterization and structure determination of a potent, selective antibody inhibitor of human MMP9.
J. Biol. Chem., 292, 2017
2GJZ
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BU of 2gjz by Molmil
Structure of Catalytic Elimination Antibody 13G5 from a crystal in space group P2(1)
Descriptor: Catalytic elimination antibody 13G5 heavy chain, Catalytic elimination antibody 13G5 light chain, ZINC ION
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2006-03-31
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Bifunctional Catalysis of Proton Transfer at an Antibody Active Site.
J.Am.Chem.Soc., 129, 2007
2GK0
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BU of 2gk0 by Molmil
Structure of Catalytic Elimination Antibody 13G5 from a twinned crystal in space group C2
Descriptor: Catalytic elimination antibody 13G5 heavy chain, Catalytic elimination antibody 13G5 light chain
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2006-03-31
Release date:2007-02-06
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Bifunctional Catalysis of Proton Transfer at an Antibody Active Site.
J.Am.Chem.Soc., 129, 2007
1CFT
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BU of 1cft by Molmil
ANTI-P24 (HIV-1) FAB FRAGMENT CB41 COMPLEXED WITH AN EPITOPE-UNRELATED D-PEPTIDE
Descriptor: PROTEIN (ANTIGEN BOUND PEPTIDE), PROTEIN (IGG2A KAPPA ANTIBODY CB41 (HEAVY CHAIN)), PROTEIN (IGG2A KAPPA ANTIBODY CB41 (LIGHT CHAIN))
Authors:Keitel, T, Kramer, A, Wessner, H, Scholz, C, Schneider-Mergener, J, Hoehne, W.
Deposit date:1999-03-19
Release date:1999-03-31
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic analysis of anti-p24 (HIV-1) monoclonal antibody cross-reactivity and polyspecificity.
Cell(Cambridge,Mass.), 91, 1997
4NHC
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BU of 4nhc by Molmil
Crystal structure of the HIV-1 neutralizing antibody 4E10 Fab fragment in complex with a hydrocarbon-stapled peptide containing the 4e10 epitope on gp41.
Descriptor: FAB HEAVY CHAIN, FAB LIGHT CHAIN, MODIFIED FRAGMENT OF HIV GLYCOPROTEIN (GP41), ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2013-11-04
Release date:2014-12-03
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.912 Å)
Cite:Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies.
Nat.Struct.Mol.Biol., 21, 2014
2R1X
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BU of 2r1x by Molmil
Crystal structure of S25-2 Fab in complex with Kdo analogues
Descriptor: 2,6-anhydro-3,5-dideoxy-D-ribo-oct-2-enonic acid-(4-8)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, Fab, antibody fragment (IgG1k), ...
Authors:Brooks, C.L, Evans, S.V.
Deposit date:2007-08-23
Release date:2008-12-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes.
J.Mol.Biol., 377, 2008
4NGH
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BU of 4ngh by Molmil
Crystal structure of the HIV-1 neutralizing antibody 4E10 Fab fragment in complex with a hydrocarbon-stapled peptide containing the 4e10 epitope on gp41 and a tethered phosphate moiety.
Descriptor: FAB HEAVY CHAIN, FAB LIGHT CHAIN, MODIFIED FRAGMENT OF HIV GLYCOPROTEIN (GP41)
Authors:Irimia, A, Wilson, I.A.
Deposit date:2013-11-01
Release date:2014-12-03
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies.
Nat.Struct.Mol.Biol., 21, 2014
8DZV
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BU of 8dzv by Molmil
Chicken anti-cardiac Troponin I antibody in complex with peptide
Descriptor: PHOSPHATE ION, POTASSIUM ION, cTnI peptide, ...
Authors:Conroy, P.J, Law, H.P.
Deposit date:2022-08-08
Release date:2023-07-26
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Design of Polarity-Dependent Immunosensors Based on the Structural Analysis of Engineered Antibodies.
Acs Chem.Biol., 18, 2023
2R2E
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BU of 2r2e by Molmil
Crystal structure of S25-2 Fab in complex with Kdo analogues
Descriptor: Fab, antibody fragment (IgG1k), heavy chain, ...
Authors:Brooks, C.L, Evans, S.V.
Deposit date:2007-08-24
Release date:2008-12-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes.
J.Mol.Biol., 377, 2008
2O5Y
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BU of 2o5y by Molmil
Crystal structure of the 1E9 LeuH47Trp/ArgH100Trp Fab progesterone complex
Descriptor: PROGESTERONE, SULFATE ION, chimeric antibody Fab 1E9-DB3
Authors:Verdino, P, Wilson, I.A.
Deposit date:2006-12-06
Release date:2007-12-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Closely related antibody receptors exploit fundamentally different strategies for steroid recognition.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2YSS
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BU of 2yss by Molmil
Crystal structure of Humanized HYHEL-10 FV mutant(HQ39KW47Y)-HEN lysozyme complex
Descriptor: ANTI-LYSOZYME ANTIBODY FV REGION, Lysozyme C
Authors:Nakanishi, T, Tsumoto, K, Yokota, A, Kondo, H, Kumagai, I.
Deposit date:2007-04-03
Release date:2008-04-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Critical contribution of VH-VL interaction to reshaping of an antibody: the case of humanization of anti-lysozyme antibody, HyHEL-10
Protein Sci., 17, 2008

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