PDB: 1517 resultsInfo pagesStatus searchChemie searchBIRD

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1E5O	Endothiapepsin complex with inhibitor DB2 Descriptor: ENDOTHIAPEPSIN, N-[(2S)-2-amino-3-phenylpropyl]-D-methionyl-L-alanyl-L-isoleucine Authors: Read, J.A, Cooper, J.B, Toldo, L, Bailey, D. Deposit date: 2000-07-28 Release date: 2000-09-07 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Refinement of Four Endothiapepsin Inhibitor Complexes. Crystallographic Studies of Cytochrome Ch from Methylobacterium Extorquens and Inhibitor Complexes of Aspartic Proteinases. Thesis, 1999
1DPJ	THE STRUCTURE OF PROTEINASE A COMPLEXED WITH IA3 PEPTIDE INHIBITOR Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEINASE A, PROTEINASE INHIBITOR IA3 PEPTIDE, ... Authors: Li, M, Phylip, H.L, Lees, W.E, Winther, J.R, Dunn, B.M, Wlodawer, A, Kay, J, Guschina, A. Deposit date: 1999-12-27 Release date: 2000-05-03 Last modified: 2021-07-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix. Nat.Struct.Biol., 7, 2000
1DP5	THE STRUCTURE OF PROTEINASE A COMPLEXED WITH A IA3 MUTANT INHIBITOR Descriptor: PROTEINASE A, PROTEINASE INHIBITOR IA3, beta-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Li, M, Phylip, H.L, Lees, W.E, Winther, J.R, Dunn, B.M, Wlodawer, A, Kay, J, Guschina, A. Deposit date: 1999-12-23 Release date: 2000-05-03 Last modified: 2021-11-03 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix. Nat.Struct.Biol., 7, 2000
1CZI	CHYMOSIN COMPLEX WITH THE INHIBITOR CP-113972 Descriptor: CHYMOSIN, CP-113972 (NORSTATINE-S-METHYL CYSTEINE-IODO-PHENYLALANINE-PROLINE) Authors: Groves, M.R, Dhanaraj, V, Pitts, J.E, Badasso, M, Hoover, D, Nugent, P, Blundell, T.L. Deposit date: 1997-01-15 Release date: 1997-04-01 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.3 Å) Cite: A 2.3 A resolution structure of chymosin complexed with a reduced bond inhibitor shows that the active site beta-hairpin flap is rearranged when compared with the native crystal structure. Protein Eng., 11, 1998
1CMS	THE THREE-DIMENSIONAL STRUCTURE OF RECOMBINANT BOVINE CHYMOSIN AT 2.3 ANGSTROMS RESOLUTION Descriptor: PROCHYMOSIN A/B PRECURSOR Authors: Gilliland, G.L, Winborne, E.L, Nachman, J, Wlodawer, A. Deposit date: 1989-10-12 Release date: 1990-01-15 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The three-dimensional structure of recombinant bovine chymosin at 2.3 A resolution. Proteins, 8, 1990
1BXQ	ACID PROTEINASE (PENICILLOPEPSIN) COMPLEX WITH PHOSPHONATE INHIBITOR. Descriptor: 2-[(1R)-1-(N-(3-METHYLBUTANOYL)-L-VALYL-L-ASPARAGINYL)-AMINO)-3-METHYLBUTYL]HYDROXYPHOSPHINYLOXY]-3-PHENYLPROPANOIC ACID METHYLESTER, ACETATE ION, GLYCEROL, ... Authors: Parrish, J.C, Khan, A.R, Fraser, M.E, Smith, W.W, Bartlett, P.A, James, M.N.G. Deposit date: 1998-10-07 Release date: 1998-10-14 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.41 Å) Cite: Lowering the entropic barrier for binding conformationally flexible inhibitors to enzymes. Biochemistry, 37, 1998
1BXO	ACID PROTEINASE (PENICILLOPEPSIN) (E.C.3.4.23.20) COMPLEX WITH PHOSPHONATE INHIBITOR: METHYL CYCLO[(2S)-2-[[(1R)-1-(N-(L-N-(3-METHYLBUTANOYL)VALYL-L-ASPARTYL)AMINO)-3-METHYLBUT YL] HYDROXYPHOSPHINYLOXY]-3-(3-AMINOMETHYL) PHENYLPROPANOATE Descriptor: GLYCEROL, METHYL CYCLO[(2S)-2-[[(1R)-1-(N-(L-N-(3-METHYLBUTANOYL)VALYL-L-ASPARTYL)AMINO)-3-METHYLBUTYL]HYDROXYPHOSPHINYLOXY]-3-(3-AMINOMETHYL)PHENYLPROPANOATE, PROTEIN (PENICILLOPEPSIN), ... Authors: Khan, A.R, Parrish, J.C, Fraser, M.E, Smith, W.W, Bartlett, P.A, James, M.N.G. Deposit date: 1998-10-07 Release date: 1998-10-14 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (0.95 Å) Cite: Lowering the entropic barrier for binding conformationally flexible inhibitors to enzymes. Biochemistry, 37, 1998
1BIM	CRYSTALLOGRAPHIC STUDIES ON THE BINDING MODES OF P2-P3 BUTANEDIAMIDE RENIN INHIBITORS Descriptor: (2S)-2-[(2-amino-1,3-thiazol-4-yl)methyl]-N~1~-{(1S,2S)-1-(cyclohexylmethyl)-2-hydroxy-2-[(3R)-1,5,5-trimethyl-2-oxopyrrolidin-3-yl]ethyl}-N~4~-[2-(dimethylamino)-2-oxoethyl]-N~4~-[(1S)-1-phenylethyl]butanediamide, Renin Authors: Tong, L. Deposit date: 1995-09-27 Release date: 1996-01-29 Last modified: 2022-03-09 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystallographic studies on the binding modes of P2-P3 butanediamide renin inhibitors. J.Biol.Chem., 270, 1995
1BIL	CRYSTALLOGRAPHIC STUDIES ON THE BINDING MODES OF P2-P3 BUTANEDIAMIDE RENIN INHIBITORS Descriptor: (2S)-2-[(2-amino-1,3-thiazol-4-yl)methyl]-N~1~-[(1S,2R,3R)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-N~4~-[2-(d imethylamino)-2-oxoethyl]-N~4~-[(1S)-1-phenylethyl]butanediamide, Renin Authors: Tong, L. Deposit date: 1995-09-27 Release date: 1996-01-29 Last modified: 2022-03-09 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystallographic studies on the binding modes of P2-P3 butanediamide renin inhibitors. J.Biol.Chem., 270, 1995
1BBS	X-RAY ANALYSES OF PEPTIDE INHIBITOR COMPLEXES DEFINE THE STRUCTURAL BASIS OF SPECIFICITY FOR HUMAN AND MOUSE RENINS Descriptor: RENIN Authors: Dhanaraj, V, Blundell, T.L. Deposit date: 1992-05-21 Release date: 1994-01-31 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (2.8 Å) Cite: X-ray analyses of peptide-inhibitor complexes define the structural basis of specificity for human and mouse renins. Nature, 357, 1992
1B5F	NATIVE CARDOSIN A FROM CYNARA CARDUNCULUS L. Descriptor: PROTEIN (CARDOSIN A), alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Frazao, C, Bento, I, Carrondo, M.A. Deposit date: 1999-01-06 Release date: 1999-01-13 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.72 Å) Cite: Crystal structure of cardosin A, a glycosylated and Arg-Gly-Asp-containing aspartic proteinase from the flowers of Cynara cardunculus L. J.Biol.Chem., 274, 1999
1AVF	ACTIVATION INTERMEDIATE 2 OF HUMAN GASTRICSIN FROM HUMAN STOMACH Descriptor: GASTRICSIN, SODIUM ION Authors: Khan, A.R, Cherney, M.M, Tarasova, N.I, James, M.N.G. Deposit date: 1997-09-16 Release date: 1998-02-25 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.36 Å) Cite: Structural characterization of activation 'intermediate 2' on the pathway to human gastricsin. Nat.Struct.Biol., 4, 1997
1APW	CRYSTALLOGRAPHIC ANALYSIS OF TRANSITION STATE MIMICS BOUND TO PENICILLOPEPSIN: DIFLUOROSTATINE-AND DIFLUOROSTATONE-CONTAINING PEPTIDES Descriptor: DIMETHYLFORMAMIDE, INHIBITOR ISOVALERYL (IVA)-VAL-VAL-DIFLUOROSTATINE-N-METHYLAMINE, PENICILLOPEPSIN, ... Authors: Sielecki, A.R, James, M.N.G. Deposit date: 1991-12-16 Release date: 1994-01-31 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystallographic analysis of transition state mimics bound to penicillopepsin: difluorostatine- and difluorostatone-containing peptides. Biochemistry, 31, 1992
1APV	CRYSTALLOGRAPHIC ANALYSIS OF TRANSITION STATE MIMICS BOUND TO PENICILLOPEPSIN: DIFLUOROSTATINE-AND DIFLUOROSTATONE-CONTAINING PEPTIDES Descriptor: DIMETHYLFORMAMIDE, INHIBITOR ISOVALERYL (IVA)-VAL-VAL-HYDRATED DIFLUOROSTATONE-N-METHYLAMINE, PENICILLOPEPSIN, ... Authors: Sielecki, A.R, James, M.N.G. Deposit date: 1991-12-16 Release date: 1994-01-31 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystallographic analysis of transition state mimics bound to penicillopepsin: difluorostatine- and difluorostatone-containing peptides. Biochemistry, 31, 1992
1APU	Crystallographic analysis of a pepstatin analogue binding to the aspartyl proteinase penicillopepsin at 1.8 angstroms resolution Descriptor: PEPSTATIN ANALOGUE ISOVALERYL-VAL-VAL-STA-O-ET, PROTEIN (PENICILLOPEPSIN), alpha-D-mannopyranose Authors: Sielecki, A.R, James, M.N.G. Deposit date: 1991-12-16 Release date: 1994-01-31 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystallographic Analysis of Transition State Mimics Bound to Penicillopepsin: Difluorostatine-and Difluorostatone-Containing Peptides Biochemistry, 31, 1992
1APT	CRYSTALLOGRAPHIC ANALYSIS OF A PEPSTATIN ANALOGUE BINDING TO THE ASPARTYL PROTEINASE PENICILLOPEPSIN AT 1.8 ANGSTROMS RESOLUTION Descriptor: INHIBITOR ISOVALERYL (IVA)-VAL-VAL-LYSTA-O-ET (LYSTA IS A LYSYL SIDE CHAIN ANALOGUE OF STATIN, PENICILLOPEPSIN, alpha-D-mannopyranose Authors: Sielecki, A.R, James, M.N.G. Deposit date: 1991-12-16 Release date: 1994-01-31 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystallographic Analysis of a Pepstatin Analogue Binding to the Aspartyl Proteinase Penicillopepsin at 1.8 Angstroms Resolution Peptides: Structure and Function, Proceedings of the of the Eighth American Peptide Symposium, 1, 1983
1AM5	THE CRYSTAL STRUCTURE AND PROPOSED AMINO ACID SEQUENCE OF A PEPSIN FROM ATLANTIC COD (GADUS MORHUA) Descriptor: PEPSIN Authors: Karlsen, S, Hough, E, Olsen, R.L. Deposit date: 1997-06-23 Release date: 1997-12-24 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Structure and proposed amino-acid sequence of a pepsin from atlantic cod (Gadus morhua). Acta Crystallogr.,Sect.D, 54, 1998

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