1APW

CRYSTALLOGRAPHIC ANALYSIS OF TRANSITION STATE MIMICS BOUND TO PENICILLOPEPSIN: DIFLUOROSTATINE-AND DIFLUOROSTATONE-CONTAINING PEPTIDES

Summary for 1APW

Entry DOI	10.2210/pdb1apw/pdb
Related	1APT 1APU 1APV
Descriptor	PENICILLOPEPSIN, INHIBITOR ISOVALERYL (IVA)-VAL-VAL-DIFLUOROSTATINE-N-METHYLAMINE, alpha-D-mannopyranose, ... (7 entities in total)
Functional Keywords	acid proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Penicillium janthinellum (Penicillium vitale)
Total number of polymer chains	2
Total formula weight	34474.88
Authors	Sielecki, A.R.,James, M.N.G. (deposition date: 1991-12-16, release date: 1994-01-31, Last modification date: 2020-07-29)
Primary citation	James, M.N.,Sielecki, A.R.,Hayakawa, K.,Gelb, M.H. Crystallographic analysis of transition state mimics bound to penicillopepsin: difluorostatine- and difluorostatone-containing peptides. Biochemistry, 31:3872-3886, 1992 Cited by PubMed: 1567842 DOI: 10.1021/bi00130a019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation