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4BK3
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Crystal structure of 3-hydroxybenzoate 6-hydroxylase uncovers lipid- assisted flavoprotein strategy for regioselective aromatic hydroxylation: Y105F mutant
Descriptor: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATIDYLGLYCEROL-PHOSPHOGLYCEROL, ...
Authors:Orru, R, Montersino, S, Barendregt, A, Westphal, A.H, van Duijn, E, Mattevi, A, van Berkel, W.J.H.
Deposit date:2013-04-21
Release date:2013-07-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal Structure of 3-Hydroxybenzoate 6-Hydroxylase Uncovers Lipid-Assisted Flavoprotein Strategy for Regioselective Aromatic Hydroxylation
J.Biol.Chem., 288, 2013
4UOK
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BU of 4uok by Molmil
Electron Cryo-microscopy of Venezuelan Equine Encephalitis Virus TC-83 in complex with neutralizing antibody Fab 3B4C-4
Descriptor: FAB FRAGMENT HEAVY CHAIN, FAB FRAGMENT LIGHT CHAIN
Authors:Porta, J, Jose, J, Roehrig, J.T, Blair, C.D, Kuhn, R.J, Rossmann, M.G.
Deposit date:2014-06-04
Release date:2014-09-17
Last modified:2019-05-29
Method:ELECTRON MICROSCOPY (18 Å)
Cite:Locking and blocking the viral landscape of an alphavirus with neutralizing antibodies.
J.Virol., 88, 2014
4UFQ
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BU of 4ufq by Molmil
Structure of a novel Hyaluronidase (Hyal_Sk) from Streptomyces koganeiensis.
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Gavira, J.A, Messina, L, Pernagallo, S, Unciti-Broceta, J.D, Conejero-Muriel, M, Diaz-Mochon, J.J, Vaccaro, S, Caruso, S, Musumeci, L, Bisicchia, S, Di Pasquale, R.
Deposit date:2015-03-18
Release date:2016-04-13
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Identification and Characterization of a Bacterial Hyaluronidase and its Production in Recombinant Form.
FEBS Lett., 590, 2016
8R2E
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BU of 8r2e by Molmil
X-ray crystallographic structure of SnoaL2 in complex with the polyketide reaction product
Descriptor: 3',4'-demethoxy-nogalose-1-hydroxy-nogalamycinone, SnoL
Authors:Schnell, R, Schneider, G.
Deposit date:2023-11-04
Release date:2024-08-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of Two-Component Mono-Oxygenases Involved in Anthracycline 1-Hydroxylation
Acs Catalysis, 2024
8R2B
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BU of 8r2b by Molmil
X-ray crystallographic structure of SnoaL2 in complex with the polyketide substrate
Descriptor: 3',4'-demethoxy-nogalose-nogalamycinone, SnoL
Authors:Schnell, R, Schneider, G.
Deposit date:2023-11-03
Release date:2024-08-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mechanism of Two-Component Mono-Oxygenases Involved in Anthracycline 1-Hydroxylation
Acs Catalysis, 2024
8SJD
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BU of 8sjd by Molmil
Cryo-EM structure of the Hermes transposase bound to two right-ends of its DNA transposon.
Descriptor: DNA (46-MER), DNA (55-MER), DNA (8-MER), ...
Authors:Lannes, L, Dyda, F.
Deposit date:2023-04-17
Release date:2023-08-02
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding.
Nat Commun, 14, 2023
4WAC
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BU of 4wac by Molmil
Crystal Structure of TarM
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Koc, C, Stehle, T, Xia, G, Peschel, A.
Deposit date:2014-08-29
Release date:2015-02-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and Enzymatic Analysis of TarM Glycosyltransferase from Staphylococcus aureus Reveals an Oligomeric Protein Specific for the Glycosylation of Wall Teichoic Acid.
J.Biol.Chem., 290, 2015
6Q84
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BU of 6q84 by Molmil
Crystal structure of RanGTP-Pdr6-eIF5A export complex
Descriptor: Eukaryotic translation initiation factor 5A-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Aksu, M, Trakhanov, S, Vera-Rodriguez, A, Gorlich, D.
Deposit date:2018-12-14
Release date:2019-05-01
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122.
J.Cell Biol., 218, 2019
4WD6
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BU of 4wd6 by Molmil
Crystal Structure of DIM-1 metallo-beta-lactamase
Descriptor: Metallo-beta-lactamase, ZINC ION
Authors:Booth, M.P.S, Kosmopoulou, M, Spencer, J.
Deposit date:2014-09-07
Release date:2014-09-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of DIM-1 metallo-beta-lactamase
To Be Published
4WAD
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BU of 4wad by Molmil
Crystal Structure of TarM with UDP-GlcNAc
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Glycosyl transferase, ...
Authors:Koc, C, Stehle, T, Xia, G, Peschel, A.
Deposit date:2014-08-29
Release date:2015-02-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and Enzymatic Analysis of TarM Glycosyltransferase from Staphylococcus aureus Reveals an Oligomeric Protein Specific for the Glycosylation of Wall Teichoic Acid.
J.Biol.Chem., 290, 2015
6Q83
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BU of 6q83 by Molmil
Crystal structure of the biportin Pdr6 in complex with UBC9
Descriptor: Importin beta-like protein KAP122, UBC9
Authors:Aksu, M, Trakhanov, S, Vera-Rodriguez, A, Gorlich, D.
Deposit date:2018-12-14
Release date:2019-05-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (4.53 Å)
Cite:Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122.
J.Cell Biol., 218, 2019
7EPG
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BU of 7epg by Molmil
Crystal structure of E.coli CcdB mutant S12G
Descriptor: CHLORIDE ION, Toxin CcdB
Authors:Manjunath, K, Varadarajan, R.
Deposit date:2021-04-26
Release date:2022-06-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.631 Å)
Cite:Mechanistic insights into global suppressors of protein folding defects.
Plos Genet., 18, 2022
7EPI
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BU of 7epi by Molmil
Crystal structure of E.coli CcdB mutant S60E
Descriptor: CHLORIDE ION, Toxin CcdB
Authors:Manjunath, K, Goyal, P, Varadarajan, R.
Deposit date:2021-04-26
Release date:2022-06-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.931 Å)
Cite:Mechanistic insights into global suppressors of protein folding defects.
Plos Genet., 18, 2022
7EPJ
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BU of 7epj by Molmil
Crystal structure of E.coli CcdB mutant V46L
Descriptor: CHLORIDE ION, Toxin CcdB
Authors:Manjunath, K, Goyal, P, Varadarajan, R.
Deposit date:2021-04-26
Release date:2022-06-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.354 Å)
Cite:Mechanistic insights into global suppressors of protein folding defects.
Plos Genet., 18, 2022
6Q82
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BU of 6q82 by Molmil
Crystal structure of the biportin Pdr6 in complex with RanGTP
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin beta-like protein KAP122, ...
Authors:Aksu, M, Vera-Rodriguez, A, Trakhanov, S, Gorlich, D.
Deposit date:2018-12-14
Release date:2019-05-01
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.994 Å)
Cite:Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122.
J.Cell Biol., 218, 2019
5IUM
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BU of 5ium by Molmil
Crystal structure of phosphorylated DesKC
Descriptor: GLYCEROL, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
Authors:Trajtenberg, F, Buschiazzo, A.
Deposit date:2016-03-18
Release date:2016-12-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.162 Å)
Cite:Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action.
Elife, 5, 2016
5JIP
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BU of 5jip by Molmil
Crystal structure of the Clostridium perfringens spore cortex lytic enzyme SleM
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cortical-lytic enzyme, MAGNESIUM ION
Authors:Chirgadze, D.Y, Christie, G, Ustok, F.I, Al-Riyami, B, Stott, K.
Deposit date:2016-04-22
Release date:2016-08-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of Clostridium perfringens SleM, a muramidase involved in cortical hydrolysis during spore germination.
Proteins, 84, 2016
8THJ
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BU of 8thj by Molmil
Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Haemophilus influenzae (antiparallel dimer)
Descriptor: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, PHOSPHATIDYLETHANOLAMINE, SODIUM ION, ...
Authors:Davies, J.S, Currie, M.C, Dobson, R.C.J, North, R.A.
Deposit date:2023-07-16
Release date:2023-11-22
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter.
Elife, 12, 2024
8THI
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BU of 8thi by Molmil
Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Haemophilus influenzae (parallel dimer)
Descriptor: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, SODIUM ION, Sialic acid TRAP transporter permease protein SiaT
Authors:Davies, J.S, Currie, M.C, Dobson, R.C.J, North, R.A.
Deposit date:2023-07-16
Release date:2023-11-22
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter.
Elife, 12, 2024
5JYC
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BU of 5jyc by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 14,15-EET hydrolysis intermediate
Descriptor: (5~{Z},11~{Z},14~{R},15~{R})-14,15-bis(oxidanyl)icosa-5,8,11-trienoic acid, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-05-13
Release date:2017-01-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3CSJ
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BU of 3csj by Molmil
Human glutathione s-transferase p1-1 in complex with chlorambucil
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORAMBUCIL, CHLORIDE ION, ...
Authors:Parker, L.J.
Deposit date:2008-04-09
Release date:2008-07-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The anti-cancer drug chlorambucil as a substrate for the human polymorphic enzyme glutathione transferase P1-1: kinetic properties and crystallographic characterisation of allelic variants.
J.Mol.Biol., 380, 2008
3D70
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BU of 3d70 by Molmil
Crystal structure of E253A mutant of BMRR bound to 22-bp oligonucleotide
Descriptor: BMR promoter DNA, GLYCEROL, IMIDAZOLE, ...
Authors:Newberry, K.J, Brennan, R.G.
Deposit date:2008-05-20
Release date:2008-08-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of BmrR-Drug Complexes Reveal a Rigid Multidrug Binding Pocket and Transcription Activation through Tyrosine Expulsion
J.Biol.Chem., 283, 2008
3DD3
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BU of 3dd3 by Molmil
Crystal Structure of the Glutathione Transferase Pi enzyme in complex with the bifunctional inhibitor, Etharapta
Descriptor: (eta6-benzene)ruthenium, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, ...
Authors:Parker, L.J.
Deposit date:2008-06-05
Release date:2009-04-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Rational design of an organometallic glutathione transferase inhibitor
Angew.Chem.Int.Ed.Engl., 48, 2009
4Y1S
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BU of 4y1s by Molmil
Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes
Descriptor: CALCIUM ION, Perforin-1
Authors:Conroy, P.J, Yagi, H, Whisstock, J.C, Norton, R.S.
Deposit date:2015-02-09
Release date:2015-09-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.611 Å)
Cite:Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes.
J.Biol.Chem., 290, 2015
5BOI
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BU of 5boi by Molmil
Bacillus megaterium YpeB C-terminal domain
Descriptor: Germination protein YpeB, SULFATE ION
Authors:Christie, G, Chirgadze, D.Y, Ustok, F.I.
Deposit date:2015-05-27
Release date:2015-08-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the PepSY-containing domain of the YpeB protein involved in germination of bacillus spores.
Proteins, 83, 2015

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