PDB: 173 resultsInfo pagesStatus searchChemie searchBIRD

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7LCA	Zoogloea ramigera biosynthetic thiolase Y218E/delH221 mutant Descriptor: Acetyl-CoA acetyltransferase, CHLORIDE ION, COENZYME A, ... Authors: Marshall, A.C, Bruning, J.B. Deposit date: 2021-01-10 Release date: 2021-09-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2 Å) Cite: Engineering potassium activation into biosynthetic thiolase. Biochem.J., 478, 2021
7LDU	Zoogloea ramigera biosynthetic thiolase Q183Y/Y218E/delH221 mutant Descriptor: Acetyl-CoA acetyltransferase, CHLORIDE ION, COENZYME A, ... Authors: Marshall, A.C, Bruning, J.B. Deposit date: 2021-01-14 Release date: 2021-09-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Engineering potassium activation into biosynthetic thiolase. Biochem.J., 478, 2021
7LDV	Zoogloea ramigera biosynthetic thiolase Q183Y/Y218E/delH221/S227K mutant Descriptor: AMMONIUM ION, Acetyl-CoA acetyltransferase, CHLORIDE ION, ... Authors: Marshall, A.C, Bruning, J.B. Deposit date: 2021-01-14 Release date: 2021-09-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Engineering potassium activation into biosynthetic thiolase. Biochem.J., 478, 2021
7LDC	Zoogloea ramigera biosynthetic thiolase Q183Y/Y218E mutant Descriptor: Acetyl-CoA acetyltransferase, COENZYME A, SULFATE ION Authors: Marshall, A.C, Bruning, J.B. Deposit date: 2021-01-13 Release date: 2021-09-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Engineering potassium activation into biosynthetic thiolase. Biochem.J., 478, 2021
7LDT	Zoogloea ramigera biosynthetic thiolase Q183Y/Y218E mutant, RbCl soak Descriptor: Acetyl-CoA acetyltransferase, COENZYME A, RUBIDIUM ION, ... Authors: Marshall, A.C, Bruning, J.B. Deposit date: 2021-01-14 Release date: 2021-09-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Engineering potassium activation into biosynthetic thiolase. Biochem.J., 478, 2021
7LDW	Zoogloea ramigera biosynthetic thiolase Q183Y/Y218E/delH221/S227K/G248T mutant Descriptor: AMMONIUM ION, Acetyl-CoA acetyltransferase, COENZYME A, ... Authors: Marshall, A.C, Bruning, J.B. Deposit date: 2021-01-14 Release date: 2021-09-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Engineering potassium activation into biosynthetic thiolase. Biochem.J., 478, 2021
7LCL	Zoogloea ramigera biosynthetic thiolase Q183Y mutant Descriptor: AMMONIUM ION, Acetyl-CoA acetyltransferase, COENZYME A, ... Authors: Marshall, A.C, Bruning, J.B. Deposit date: 2021-01-11 Release date: 2021-09-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.295 Å) Cite: Engineering potassium activation into biosynthetic thiolase. Biochem.J., 478, 2021
7LD2	Zoogloea ramigera biosynthetic thiolase Q183Y mutant, RbCl soak Descriptor: Acetyl-CoA acetyltransferase, CHLORIDE ION, COENZYME A, ... Authors: Marshall, A.C, Bruning, J.B. Deposit date: 2021-01-12 Release date: 2021-09-01 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Engineering potassium activation into biosynthetic thiolase. Biochem.J., 478, 2021
7YXM	Benzoylsuccinyl-CoA thiolase with coenzyme A Descriptor: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Benzoylsuccinyl-CoA thiolase subunit, ... Authors: Ermler, U, Heider, J, Weidenweber, S. Deposit date: 2022-02-16 Release date: 2022-04-06 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Finis tolueni: a new type of thiolase with an integrated Zn-finger subunit catalyzes the final step of anaerobic toluene metabolism. Febs J., 289, 2022
7PYT	Benzoylsuccinyl-CoA thiolase with coenzyme A Descriptor: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Benzoylsuccinyl-CoA thiolase subunit, ... Authors: Ermler, U, Heider, J, Weidenweber, S, Demmer, U. Deposit date: 2021-10-11 Release date: 2022-04-06 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Finis tolueni: a new type of thiolase with an integrated Zn-finger subunit catalyzes the final step of anaerobic toluene metabolism. Febs J., 289, 2022
7PXP	Benzoylsuccinyl-CoA thiolase Descriptor: Benzoylsuccinyl-CoA thiolase subunit, ZINC ION Authors: Ermler, U, Heider, H, Weidenweber, S, Demmer, U. Deposit date: 2021-10-08 Release date: 2022-04-06 Last modified: 2022-09-28 Method: X-RAY DIFFRACTION (2 Å) Cite: Finis tolueni: a new type of thiolase with an integrated Zn-finger subunit catalyzes the final step of anaerobic toluene metabolism. Febs J., 289, 2022
7FEA	PY14 in complex with Col-D Descriptor: (6~{R},7~{R},9~{E})-6,7-bis(oxidanyl)hexadeca-9,15-dien-11,13-diynoic acid, Acetyl-CoA C-acyltransferase Authors: Lin, C.C, Ko, T.P, Huang, K.F, Yang, Y.L. Deposit date: 2021-07-19 Release date: 2022-07-27 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Integrated omics approach to unveil antifungal bacterial polyynes as acetyl-CoA acetyltransferase inhibitors. Commun Biol, 5, 2022
7VTR	3-ketoacyl-CoA thiolase Tfu_0875 Descriptor: Thiolase Authors: Liu, L.X, Zhou, S.H, Deng, Y. Deposit date: 2021-10-30 Release date: 2022-11-02 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Rational Design of the Substrate Tunnel of beta-Ketothiolase Reveals a Local Cationic Domain Modulated Rule that Improves the Efficiency of Claisen Condensation Acs Catalysis, 13, 2023
7XLY	Crystal structure of FadA2 (Rv0243) from the fatty acid metabolic pathway of Mycobacterium tuberculosis Descriptor: Probable acetyl-CoA acyltransferase FadA2 (3-ketoacyl-CoA thiolase) (Beta-ketothiolase), SULFATE ION Authors: Singh, R, Kundu, P, Singh, B.K, Bhattacharyya, S, Das, A.K. Deposit date: 2022-04-23 Release date: 2023-04-26 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Crystal structure of FadA2 thiolase from Mycobacterium tuberculosis and prediction of its substrate specificity and membrane-anchoring properties. Febs J., 290, 2023
8BNU	Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) tetrameric complex Descriptor: 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha Authors: Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R. Deposit date: 2022-11-14 Release date: 2023-05-17 Last modified: 2023-07-19 Method: ELECTRON MICROSCOPY (3.55 Å) Cite: Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes. Structure, 31, 2023
8BRJ	Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) trimeric complex Descriptor: 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha Authors: Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R. Deposit date: 2022-11-23 Release date: 2023-05-17 Last modified: 2023-07-19 Method: ELECTRON MICROSCOPY (4.08 Å) Cite: Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes. Structure, 31, 2023
8BNR	Escherichia coli anaerobic fatty acid beta oxidation trifunctional enzyme (anEcTFE) octameric complex Descriptor: 3-ketoacyl-CoA thiolase FadI, Fatty acid oxidation complex subunit alpha Authors: Sah-Teli, S.K, Pinkas, M, Novacek, J, Venkatesan, R. Deposit date: 2022-11-14 Release date: 2023-05-17 Last modified: 2023-11-29 Method: ELECTRON MICROSCOPY (10.3 Å) Cite: Structural basis for different membrane-binding properties of E. coli anaerobic and human mitochondrial beta-oxidation trifunctional enzymes. Structure, 31, 2023
8ECM	Crystal Structure Analysis of Acetyl-CoA acetyltransferase from Firmicutes bacterium Descriptor: Acetyl-CoA acetyltransferase Authors: Seo, H.S, Dhe-Paganon, S. Deposit date: 2022-09-02 Release date: 2023-05-31 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease. Nat Med, 29, 2023
8K1C	Structural insight into the role of acetyl-CoA acetyltransferase from Fusobacterium nucleatum Descriptor: Acetyl-CoA acetyltransferase Authors: He, S.R, Bai, X, Zhang, J, Zhao, Z.D. Deposit date: 2023-07-10 Release date: 2023-08-02 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (1.894 Å) Cite: Structural insight into the role of acetyl-CoA acetyltransferase from Fusobacterium nucleatum To Be Published
7YVY	Crystal structure of thiolase PFC_04095 from Pyrococcus furiosus Descriptor: Acetyl-CoA acetyltransferase Authors: Singh, R, Das, A.K. Deposit date: 2022-08-20 Release date: 2023-09-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structure of thiolase PFC_04095 from Pyrococcus furiosus To Be Published
8OQL	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-1 Descriptor: 3-hydroxyacyl-CoA dehydrogenase, FORMAMIDE, GLYCEROL, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-12 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
8OPW	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Caffeine (Fragment-B-51) Descriptor: 3-hydroxyacyl-CoA dehydrogenase, CAFFEINE, GLYCEROL, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-10 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.52 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
8OQS	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-83 Descriptor: 3-hydroxyacyl-CoA dehydrogenase, 4-phenylbenzenesulfonic acid, GLYCEROL, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-12 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.33 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
8OQM	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-10 Descriptor: 3-hydroxyacyl-CoA dehydrogenase, 6-azanyl-4-oxidanyl-naphthalene-2-sulfonic acid, GLYCEROL, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-12 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
8OQN	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-53 Descriptor: 1-benzyl-1H-pyrazole-4-carboxylic acid, 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-12 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024

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