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7PVZ
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BU of 7pvz by Molmil
Crystal structure of the intertwined dimer of the c-Src SH3 domain E93V-S94A-R95S-T96G mutant
Descriptor: Isoform 2 of Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A, Salinas Garcia, M.C.
Deposit date:2021-10-05
Release date:2022-11-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:The effect of the hinge loops composition in the domain swapping of the SH3 domain
To be published
7S4R
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BU of 7s4r by Molmil
Serial Macromolecular Crystallography at ALBA Synchrotron Light Source - alpha Spectrin-SH3 domain
Descriptor: Spectrin alpha chain, non-erythrocytic 1
Authors:Martin-Garcia, J.M, Botha, S, Hu, H, Jernigan, R, Castellvi, A, Lisova, S, Gil, F, Calisto, B, Crespo, I, Roy-Chowdbury, S, Grieco, A, Ketawala, G, Weierstall, U, Spence, J, Fromme, P, Zatsepin, N, Boer, R, Carpena, X.
Deposit date:2021-09-09
Release date:2021-10-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Serial macromolecular crystallography at ALBA Synchrotron Light Source.
J.Synchrotron Radiat., 29, 2022
5NP3
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Abl2 SH3
Descriptor: Abelson tyrosine-protein kinase 2
Authors:Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L.
Deposit date:2017-04-13
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
5NP5
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BU of 5np5 by Molmil
Abl2 SH3 pTyr116/161
Descriptor: Abelson tyrosine-protein kinase 2, SULFATE ION
Authors:Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L.
Deposit date:2017-04-13
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
5O2P
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BU of 5o2p by Molmil
p130Cas SH3 domain PTP-PEST peptide chimera
Descriptor: Breast cancer anti-estrogen resistance 1,Tyrosine-protein phosphatase non-receptor type 12
Authors:Hexnerova, R, Veverka, V.
Deposit date:2017-05-22
Release date:2017-09-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.
Sci Rep, 7, 2017
5OAZ
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BU of 5oaz by Molmil
Crystal structure of the Abl-SH3 domain at pH 7.5
Descriptor: DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A.
Deposit date:2017-06-25
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.03 Å)
Cite:Crystal structure of the Abl-SH3 domain at pH 7.5
to be published
5O2M
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p130Cas SH3 domain
Descriptor: Breast cancer anti-estrogen resistance 1
Authors:Hexnerova, R, Veverka, V.
Deposit date:2017-05-22
Release date:2017-09-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.
Sci Rep, 7, 2017
5NP2
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BU of 5np2 by Molmil
Abl1 SH3 pTyr89/134
Descriptor: Tyrosine-protein kinase ABL1
Authors:Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L.
Deposit date:2017-04-13
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
5OB2
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BU of 5ob2 by Molmil
Crystal structure of the c-Src-SH3 domain E97T mutant in complex with the high affinity peptide APP12
Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2017-06-25
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the c-Src-SH3 domain E97T mutant in complex with the high affinity peptide APP12
to be published
5OB0
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BU of 5ob0 by Molmil
Crystal structure of the c-Src-SH3 domain Q128E mutant in complex with the high affinity peptide APP12
Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION
Authors:Camara-Artigas, A.
Deposit date:2017-06-25
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.172 Å)
Cite:Crystal structure of the c-Src-SH3 domain Q128E mutant in complex with the high affinity peptide APP12
to be published
5OAV
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BU of 5oav by Molmil
High resolution crystal structure of the c-Src-SH3 domain mutant E93V in complex with the high affinity synthetic peptide APP12: monoclinic crystal
Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2017-06-23
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:High resolution crystal structure of the c-Src-SH3 domain mutant E93V in complex with the high affinity synthetic peptide APP12: monoclinic crystal
to be published
5OB1
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BU of 5ob1 by Molmil
Crystal structure of the c-Src-SH3 domain Q128R mutant in complex with the high affinity peptide APP12
Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2017-06-25
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.172 Å)
Cite:Crystal structure of the c-Src-SH3 domain Q128R mutant in complex with the high affinity peptide APP12
to be published
5O2Q
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BU of 5o2q by Molmil
p130Cas SH3 domain Vinculin peptide chimera
Descriptor: Breast cancer anti-estrogen resistance 1,Vinculin
Authors:Hexnerova, R, Veverka, V.
Deposit date:2017-05-22
Release date:2017-09-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.
Sci Rep, 7, 2017
2RNA
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BU of 2rna by Molmil
Itk SH3 average minimized
Descriptor: Tyrosine-protein kinase ITK/TSK
Authors:Severin, A.J.
Deposit date:2007-12-08
Release date:2007-12-25
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:NMR structure note: murine Itk SH3 domain
To be Published
2RMO
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BU of 2rmo by Molmil
Solution structure of alpha-spectrin_SH3-bergerac from Chicken
Descriptor: Spectrin alpha chain, brain
Authors:Kutyshenko, V.P, Prokhorov, D.A, Timchenko, M.A, Kudrevatykh, Y.A, Fedyukina, D.V, Gushchina, L.V, Khristoforov, V.S, Filimonov, V.V.
Deposit date:2007-11-07
Release date:2008-09-30
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Study of the structure and dynamics of a chimeric variant of the SH3 domain (SHA-Bergerac) by NMR spectroscopy
Russ.J.Bioorganic Chem., 34, 2008
5FW9
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BU of 5fw9 by Molmil
Human Spectrin SH3 domain D48G, E7Y, K60Y
Descriptor: SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1
Authors:Gallego, P, Navarro, S, Ventura, S, Reverter, D.
Deposit date:2016-02-12
Release date:2016-12-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Human Spectrin SH3 Domain D48G, E7Y, K60Y
To be Published
2RQV
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BU of 2rqv by Molmil
Solution structure of SH3CI domain of Bem1p
Descriptor: Bud emergence protein 1
Authors:Takaku, T, Ogura, K, Inagaki, F.
Deposit date:2009-12-21
Release date:2010-04-21
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of a novel Cdc42-binding module of Bem1 and its interaction with Ste20 and Cdc42
J.Biol.Chem., 285, 2010
5FWC
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BU of 5fwc by Molmil
Human Spectrin SH3 domain D48G, E7A, K60A
Descriptor: 1,2-ETHANEDIOL, AMMONIUM ION, SPECTRIN ALPHA CHAIN, ...
Authors:Gallego, P, Navarro, S, Ventura, S, Reverter, D.
Deposit date:2016-02-12
Release date:2016-12-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Human Spectrin SH3 Domain D48G, E7A, K60A
To be Published
5FWB
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BU of 5fwb by Molmil
Human Spectrin SH3 domain D48G, E7F, K60F
Descriptor: SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1
Authors:Gallego, P, Navarro, S, Ventura, S, Reverter, D.
Deposit date:2016-02-12
Release date:2016-12-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Human Spectrin SH3 Domain D48G, E7F, K60F
To be Published
2RQW
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BU of 2rqw by Molmil
Solution structure of Bem1p SH3CI domain complexed with Ste20p-PRR peptide
Descriptor: 24-meric peptide from Serine/threonine-protein kinase STE20, Bud emergence protein 1
Authors:Takaku, T, Ogura, K, Inagaki, F.
Deposit date:2009-12-21
Release date:2010-04-21
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of a novel Cdc42-binding module of Bem1 and its interaction with Ste20 and Cdc42
J.Biol.Chem., 285, 2010
2RPN
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BU of 2rpn by Molmil
A crucial role for high intrinsic specificity in the function of yeast SH3 domains
Descriptor: Actin-binding protein, Actin-regulating kinase 1
Authors:Stollar, E.J, Garcia, B, Chong, A, Forman-Kay, J, Davidson, A.
Deposit date:2008-06-12
Release date:2009-06-16
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p
J.Biol.Chem., 284, 2009
2SEM
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BU of 2sem by Molmil
SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR
Descriptor: PROTEIN (SEX MUSCLE ABNORMAL PROTEIN 5), PROTEIN (SH3 PEPTOID INHIBITOR)
Authors:Nguyen, J.T, Turck, C.W, Cohen, F.E, Zuckermann, R.N, Lim, W.A.
Deposit date:1998-11-02
Release date:1999-01-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors.
Science, 282, 1998
1GCQ
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BU of 1gcq by Molmil
CRYSTAL STRUCTURE OF VAV AND GRB2 SH3 DOMAINS
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, VAV PROTO-ONCOGENE
Authors:Nishida, M, Nagata, K, Hachimori, Y, Ogura, K, Inagaki, F.
Deposit date:2000-08-08
Release date:2001-08-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Novel recognition mode between Vav and Grb2 SH3 domains.
EMBO J., 20, 2001
1GFD
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BU of 1gfd by Molmil
SOLUTION STRUCTURE AND LIGAND-BINDING SITE OF THE C-TERMINAL SH3 DOMAIN OF GRB2
Descriptor: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
Authors:Kohda, D, Terasawa, H, Hatanaka, H, Inagaki, F.
Deposit date:1994-06-13
Release date:1994-08-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2.
Structure, 2, 1994
1GBQ
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BU of 1gbq by Molmil
SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, MINIMIZED AVERAGE STRUCTURE
Descriptor: GRB2, SOS-1
Authors:Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L.
Deposit date:1996-12-23
Release date:1997-09-04
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.
J.Mol.Biol., 267, 1997

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