7ROR
 
 | | Plasmodium falciparum tyrosyl-tRNA synthetase in complex with tyrosine-AMP | | Descriptor: | 5'-O-[(S)-{[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]oxy}(hydroxy)phosphoryl]adenosine, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W. | | Deposit date: | 2021-08-02 | | Release date: | 2022-06-08 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy.
Science, 376, 2022
|
|
7ROS
 | | Plasmodium falciparum tyrosyl-tRNA synthetase in complex with ML901-Tyr | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Tyrosine--tRNA ligase, ... | | Authors: | Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W. | | Deposit date: | 2021-08-02 | | Release date: | 2022-06-08 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy.
Science, 376, 2022
|
|
7ROT
 | | Plasmodium falciparum tyrosyl-tRNA synthetase, S234C mutant, in complex with ML901-Tyr | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Tyrosine--tRNA ligase, ... | | Authors: | Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W. | | Deposit date: | 2021-08-02 | | Release date: | 2022-06-08 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy.
Science, 376, 2022
|
|
4G85
 | | Crystal structure of human HisRS | | Descriptor: | Histidine-tRNA ligase, cytoplasmic | | Authors: | Wei, Z, Wu, J, Zhou, J.J, Yang, X.-L, Zhang, M, Schimmel, P. | | Deposit date: | 2012-07-21 | | Release date: | 2012-09-26 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.11 Å) | | Cite: | Internally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for Repurposing.
Structure, 20, 2012
|
|
5NOH
 | | HRSV M2-1 core domain | | Descriptor: | Transcription elongation factor M2-1 | | Authors: | Josts, I, Almeida Hernandez, Y, Molina, I.G, de Prat-Gay, G, Tidow, H. | | Deposit date: | 2017-04-12 | | Release date: | 2018-01-03 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure and stability of the Human respiratory syncytial virus M2-1RNA-binding core domain reveals a compact and cooperative folding unit.
Acta Crystallogr F Struct Biol Commun, 74, 2018
|
|
5NKX
 | | HRSV M2-1 core domain, P3221 crystal form | | Descriptor: | M2-1 | | Authors: | Almeida Hernandez, Y, Josts, I, Molina, I.G, de Pray-Gay, G, Tidow, H. | | Deposit date: | 2017-04-03 | | Release date: | 2018-01-03 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.00008678 Å) | | Cite: | Structure and stability of the Human respiratory syncytial virus M2-1RNA-binding core domain reveals a compact and cooperative folding unit.
Acta Crystallogr F Struct Biol Commun, 74, 2018
|
|
1AUD
 | | U1A-UTRRNA, NMR, 31 STRUCTURES | | Descriptor: | RNA 3UTR, U1A 102 | | Authors: | Allain, F.H.-T, Gubser, C.C, Howe, P.W.A, Nagai, K, Neuhaus, D, Varani, G. | | Deposit date: | 1997-08-22 | | Release date: | 1998-02-25 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structural basis of the RNA-binding specificity of human U1A protein.
EMBO J., 16, 1997
|
|
6OD8
 | |
4H4A
 | |
7YP8
 | | Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Leucyl-sulfamoyl 3-deazaadenosine | | Descriptor: | 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... | | Authors: | Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D. | | Deposit date: | 2022-08-02 | | Release date: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The essential role of a structured water in base recognition of Class II aminoacyl-tRNA synthetases
To be published
|
|
6JXM
 | | Crystal Structure of phi29 pRNA domain II | | Descriptor: | BARIUM ION, MAGNESIUM ION, RNA (97-mer) | | Authors: | Cai, R, Price, I.R, Ding, F, Wu, F, Chen, T, Zhang, Y, Liu, G, Jardine, P.J, Lu, C, Ke, A. | | Deposit date: | 2019-04-24 | | Release date: | 2019-08-21 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.32 Å) | | Cite: | ATP/ADP modulates gp16-pRNA conformational change in the Phi29 DNA packaging motor.
Nucleic Acids Res., 47, 2019
|
|
1TYA
 | |
1TYB
 | |
7OI3
 | | Cryo-EM structure of the Cetacean morbillivirus nucleoprotein-RNA complex | | Descriptor: | Cetacean morbillivirus nucleoprotein, poly-A 6-mer | | Authors: | Zinzula, L, Beck, F, Klumpe, S, Bohn, S, Pfeifer, G, Bollschweiler, D, Nagy, I, Plitzko, J.M, Baumeister, W. | | Deposit date: | 2021-05-11 | | Release date: | 2021-06-23 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Cryo-EM structure of the cetacean morbillivirus nucleoprotein-RNA complex.
J.Struct.Biol., 213, 2021
|
|
2AP0
 | |
2AP5
 | |
1S03
 | |
3TZL
 | | Crystal Structure of Tryptophanyl-tRNA Synthetase from Campylobacter jejuni complexed with ADP and Tryptophane | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, SODIUM ION, ... | | Authors: | Kim, Y, Zhou, M, Grimshaw, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2011-09-27 | | Release date: | 2011-10-05 | | Method: | X-RAY DIFFRACTION (2.154 Å) | | Cite: | Crystal Structure of Tryptophanyl-tRNA Synthetase from Campylobacter jejuni complexed with ADP and Tryptophane
To be Published
|
|
7E8O
 | |
1RKJ
 | | Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target | | Descriptor: | 5'-R(*GP*GP*AP*UP*GP*CP*CP*UP*CP*CP*CP*GP*AP*GP*UP*GP*CP*AP*UP*CP*C)-3', Nucleolin | | Authors: | Johansson, C, Finger, L.D, Trantirek, L, Mueller, T.D, Kim, S, Laird-Offringa, I.A, Feigon, J. | | Deposit date: | 2003-11-21 | | Release date: | 2004-04-27 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target.
J.Mol.Biol., 337, 2004
|
|
1CQ5
 | | NMR STRUCTURE OF SRP RNA DOMAIN IV | | Descriptor: | SRP RNA DOMAIN IV | | Authors: | Schmitz, U, James, T.L, Behrens, S, Freymann, D.M, Lukavsky, P, Walter, P. | | Deposit date: | 1999-08-05 | | Release date: | 1999-08-23 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure of the phylogenetically most conserved domain of SRP RNA.
RNA, 5, 1999
|
|
1CQL
 | |
3IIN
 | | Plasticity of the kink turn structural motif | | Descriptor: | DNA/RNA (5'-R(*AP*AP*GP*CP*CP*AP*CP*AP*CP*AP*GP*AP*CP*C)-D(P*AP*GP*A)-R(P*CP*GP*GP*CP*C)-3'), DNA/RNA (5'-R(*CP*A)-D(P*T)-3'), Group I intron, ... | | Authors: | Lipchock, S.V, Strobel, S.A, Antonioli, A.H, Cochrane, J.C. | | Deposit date: | 2009-08-02 | | Release date: | 2010-03-09 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (4.18 Å) | | Cite: | Plasticity of the RNA kink turn structural motif.
Rna, 16, 2010
|
|
4PBT
 | | Crystal structure of the M. jannaschii G2 tRNA synthetase variant bound to 4-trans-cyclooctene-amidopheylalanine (Tco-amF) | | Descriptor: | 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 4-{[(1R,4E)-cyclooct-4-en-1-ylcarbonyl]amino}-L-phenylalanine, GLYCEROL, ... | | Authors: | Cooley, R.B, Karplus, P.A, Mehl, R.A. | | Deposit date: | 2014-04-13 | | Release date: | 2014-07-23 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Gleaning Unexpected Fruits from Hard-Won Synthetases: Probing Principles of Permissivity in Non-canonical Amino Acid-tRNA Synthetases.
Chembiochem, 15, 2014
|
|
4PBR
 | | Crystal structure of the M. jannaschii G2 tRNA synthetase variant bound to 4-(2-bromoisobutyramido)-phenylalanine (BibaF) | | Descriptor: | 4-[(2-bromo-2-methylpropanoyl)amino]-L-phenylalanine, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Cooley, R.B, Karplus, P.A, Mehl, R.A. | | Deposit date: | 2014-04-13 | | Release date: | 2014-07-23 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Gleaning Unexpected Fruits from Hard-Won Synthetases: Probing Principles of Permissivity in Non-canonical Amino Acid-tRNA Synthetases.
Chembiochem, 15, 2014
|
|
