6B4G
| Crystal structure of Chaetomium thermophilum Gle1 CTD-Nup42 GBM complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nucleoporin AMO1, Nucleoporin GLE1 | Authors: | Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A. | Deposit date: | 2017-09-26 | Release date: | 2018-06-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.648 Å) | Cite: | Structural and functional analysis of mRNA export regulation by the nuclear pore complex. Nat Commun, 9, 2018
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8PJ1
| Structure of human 48S translation initiation complex in open codon scanning state (48S-1) | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. | Deposit date: | 2023-06-22 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining Nat.Struct.Mol.Biol., 2024
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8PJ4
| Structure of human 48S translation initiation complex after eIF5 release (48S-4) | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. | Deposit date: | 2023-06-22 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining Nat.Struct.Mol.Biol., 2024
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8PJ5
| Structure of human 48S translation initiation complex after eIF2 release prior 60S subunit joining (48S-5) | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. | Deposit date: | 2023-06-22 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining Nat.Struct.Mol.Biol., 2024
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5JR9
| Crystal structure of apo-NeC3PO | Descriptor: | NEQ131 | Authors: | Zhang, J, Gan, J. | Deposit date: | 2016-05-06 | Release date: | 2016-09-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for single-stranded RNA recognition and cleavage by C3PO Nucleic Acids Res., 44, 2016
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6B4H
| Crystal structure of Chaetomium thermophilum Gle1 CTD-Nup42 GBM-IP6 complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, INOSITOL HEXAKISPHOSPHATE, Nucleoporin AMO1, ... | Authors: | Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A. | Deposit date: | 2017-09-26 | Release date: | 2018-06-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Structural and functional analysis of mRNA export regulation by the nuclear pore complex. Nat Commun, 9, 2018
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6B4E
| Crystal structure of Saccharomyces cerevisiae Gle1 CTD-Nup42 GBM complex | Descriptor: | 1,2-ETHANEDIOL, Nucleoporin GLE1, Nucleoporin NUP42, ... | Authors: | Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A. | Deposit date: | 2017-09-26 | Release date: | 2018-06-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural and functional analysis of mRNA export regulation by the nuclear pore complex. Nat Commun, 9, 2018
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7ZOL
| Cryo-EM structure of a CRISPR effector in complex with regulator | Descriptor: | Cas7-11, TPR-CHAT, ZINC ION, ... | Authors: | Babatunde, E.E, Davide, T, Bertrand, B, Sergey, N, Alexander, M, Henning, S, Dong, C.N. | Deposit date: | 2022-04-26 | Release date: | 2022-11-30 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Structural insights into the regulation of Cas7-11 by TPR-CHAT. Nat.Struct.Mol.Biol., 30, 2023
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8GXC
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5O3J
| Crystal structure of TIA-1 RRM2 in complex with RNA | Descriptor: | Nucleolysin TIA-1 isoform p40, RNA (5'-R(P*UP*UP*C)-3') | Authors: | Sonntag, M, Jagtap, P.K.A, Hennig, J, Sattler, M. | Deposit date: | 2017-05-24 | Release date: | 2017-07-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.97 Å) | Cite: | Segmental, Domain-Selective Perdeuteration and Small-Angle Neutron Scattering for Structural Analysis of Multi-Domain Proteins. Angew. Chem. Int. Ed. Engl., 56, 2017
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7VYX
| Crystal structure of the selenomethionine(SeMet)-derived Cas12c1 (D969A) ternary complex | Descriptor: | Non-target DNA strand, Selenomethionine (SeMet)-labeled Cas12c1 D969A mutant, Target DNA strand, ... | Authors: | Zhang, B, Lin, J.Y, Perculija, V, OuYang, S.Y. | Deposit date: | 2021-11-15 | Release date: | 2022-11-02 | Last modified: | 2023-06-14 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural insights into target DNA recognition and cleavage by the CRISPR-Cas12c1 system Nucleic Acids Res., 50, 2022
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5NJU
| Flavivirus NS5 domain | Descriptor: | Genome polyprotein, MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Talapatra, S.K, Chatrin, C, Kozielski, F. | Deposit date: | 2017-03-29 | Release date: | 2018-01-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure of the binary methyltransferase-SAH complex from Zika virus reveals a novel conformation for the mechanism of mRNA capping. Oncotarget, 9, 2018
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5NJV
| Flavivirus NS5 domain | Descriptor: | CHLORIDE ION, NS5, S-ADENOSYLMETHIONINE | Authors: | Talapatra, S.K, Chatrin, C, Kozielski, F. | Deposit date: | 2017-03-29 | Release date: | 2018-01-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure of the binary methyltransferase-SAH complex from Zika virus reveals a novel conformation for the mechanism of mRNA capping. Oncotarget, 9, 2018
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6RNS
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4PMW
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1HH2
| Crystal structure of NusA from Thermotoga maritima | Descriptor: | N UTILIZATION SUBSTANCE PROTEIN A | Authors: | Worbs, M, Bourenkov, G.P, Bartunik, H.D, Huber, R, Wahl, M.C. | Deposit date: | 2000-12-18 | Release date: | 2001-10-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | An Extended RNA Binding Surface Through Arrayed S1 and Kh Domains in Transcription Factor Nusa Mol.Cell, 7, 2001
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8AXX
| Expanded Coxsackievirus A9 after treatment with endosomal ionic buffer | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | Authors: | Domanska, A, Plavec, Z, Ruokolainen, V, Loflund, B, Marjomaki, V.S, Butcher, S.J. | Deposit date: | 2022-09-01 | Release date: | 2022-10-19 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural Studies Reveal that Endosomal Cations Promote Formation of Infectious Coxsackievirus A9 A-Particles, Facilitating RNA and VP4 Release. J.Virol., 96, 2022
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8AW6
| Expanded Coxsackievirus A9 after 0.01% faf-BSA treatment | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | Authors: | Domanska, A, Plavec, Z, Ruokolainen, V, Loflund, B, Marjomaki, V.S, Butcher, S.J. | Deposit date: | 2022-08-29 | Release date: | 2022-10-26 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural Studies Reveal that Endosomal Cations Promote Formation of Infectious Coxsackievirus A9 A-Particles, Facilitating RNA and VP4 Release. J.Virol., 96, 2022
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8AT5
| native Coxsackievirus A9 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Domanska, A, Plavec, Z, Ruokolainen, V, Marjomaki, V.S, Butcher, S.J. | Deposit date: | 2022-08-22 | Release date: | 2022-11-16 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural Studies Reveal that Endosomal Cations Promote Formation of Infectious Coxsackievirus A9 A-Particles, Facilitating RNA and VP4 Release. J.Virol., 96, 2022
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3ODZ
| Crystal structure of P38alpha Y323R active mutant | Descriptor: | Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | Authors: | Livnah, O, Tzarum, N. | Deposit date: | 2010-08-12 | Release date: | 2011-01-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Active mutants of the TCR-mediated p38alpha alternative activation site show changes in the phosphorylation lip and DEF site formation. J.Mol.Biol., 405, 2011
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8SP3
| Asymmetric dimer of MapSPARTA bound with gRNA/tDNA hybrid | Descriptor: | MAGNESIUM ION, TIR-APAZ, guide RNA, ... | Authors: | Shen, Z.F, Yang, X.Y, Fu, T.M. | Deposit date: | 2023-05-01 | Release date: | 2023-08-23 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Oligomerization-mediated activation of a short prokaryotic Argonaute. Nature, 621, 2023
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8SP0
| Symmetric dimer of MapSPARTA bound with gRNA/tDNA hybrid | Descriptor: | MAGNESIUM ION, TIR-APAZ, guide RNA, ... | Authors: | Shen, Z.F, Yang, X.Y, Fu, T.M. | Deposit date: | 2023-05-01 | Release date: | 2023-08-23 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Oligomerization-mediated activation of a short prokaryotic Argonaute. Nature, 621, 2023
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5JRE
| Crystal structure of NeC3PO in complex with ssDNA. | Descriptor: | 9-METHYL-9H-PURIN-6-AMINE, ADENINE, NEQ131, ... | Authors: | Gan, J, Zhang, J. | Deposit date: | 2016-05-06 | Release date: | 2016-09-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for single-stranded RNA recognition and cleavage by C3PO Nucleic Acids Res., 44, 2016
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2C78
| EF-Tu complexed with a GTP analog and the antibiotic pulvomycin | Descriptor: | (1S,2S,3E,5E,7E,10S,11S,12S)-12-[(2R,4E,6E,8Z,10R,12E,14E,16Z,18S,19Z)-10,18-DIHYDROXY-12,16,19-TRIMETHYL-11,22-DIOXOOX ACYCLODOCOSA-4,6,8,12,14,16,19-HEPTAEN-2-YL]-2,11-DIHYDROXY-1,10-DIMETHYL-9-OXOTRIDECA-3,5,7-TRIEN-1-YL 6-DEOXY-2,4-DI-O-METHYL-BETA-L-GALACTOPYRANOSIDE, ELONGATION FACTOR TU-A, MAGNESIUM ION, ... | Authors: | Parmeggiani, A, Krab, I.M, Okamura, S, Nielsen, R.C, Nyborg, J, Nissen, P. | Deposit date: | 2005-11-18 | Release date: | 2006-03-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu. Biochemistry, 45, 2006
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7MI2
| Seb1-G476S RNA binding domain | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Rpb7-binding protein seb1 | Authors: | Jacewicz, A, Shuman, S. | Deposit date: | 2021-04-16 | Release date: | 2021-07-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Genetic screen for suppression of transcriptional interference identifies a gain-of-function mutation in Pol2 termination factor Seb1. Proc.Natl.Acad.Sci.USA, 118, 2021
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