PDB: 36939 resultsInfo pagesStatus searchChemie searchBIRD

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3NFP	Crystal structure of the Fab fragment of therapeutic antibody daclizumab in complex with IL-2Ra (CD25) ectodomain Descriptor: Heavy chain of Fab fragment of daclizumab, Interleukin-2 receptor subunit alpha, Light chain of Fab fragment of daclizumab Authors: Yang, H, Wang, J, Du, J, Zhong, C, Guo, Y, Ding, J. Deposit date: 2010-06-10 Release date: 2010-09-15 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.86 Å) Cite: Structural basis of immunosuppression by the therapeutic antibody daclizumab Cell Res., 20, 2010
7DJO	The co-crystal structure of DYRK2 with a small molecule inhibitor 17 Descriptor: Dual specificity tyrosine-phosphorylation-regulated kinase 2, [2,7-dimethoxy-9-[[(3S)-pyrrolidin-3-yl]methylsulfanyl]acridin-4-yl]methanol Authors: Wei, T, Xiao, J. Deposit date: 2020-11-20 Release date: 2021-11-24 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.499 Å) Cite: Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
6EBR	Activation of RR02 bound to BeF3 Descriptor: BERYLLIUM TRIFLUORIDE ION, DNA-binding response regulator, MANGANESE (II) ION Authors: Riboldi-Tunnicliffe, A, Panjikar, S. Deposit date: 2018-08-06 Release date: 2019-11-13 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.816 Å) Cite: Activation of RR02 bound to BeF3 To Be Published
3N9E	Mite-y Lysozyme: Promite Descriptor: CHLORIDE ION, Lysozyme C Authors: Newman, J, Peat, T.S. Deposit date: 2010-05-28 Release date: 2011-06-08 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.38 Å) Cite: Mite-y Lysozyme Crystals and Structures To be Published
4E3U	Crystal Structure of Hen Egg White Lysozyme Cryoprotected in Proline Descriptor: CHLORIDE ION, Lysozyme C, PROLINE Authors: Tanner, J.J, Pemberton, T.A. Deposit date: 2012-03-10 Release date: 2012-07-25 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Proline: Mother Nature's cryoprotectant applied to protein crystallography. Acta Crystallogr.,Sect.D, 68, 2012
3NJU	Crystal structure of the complex of group I phospholipase A2 with 4-Methoxy-benzoicacid at 1.4A resolution Descriptor: 4-METHOXYBENZOIC ACID, CALCIUM ION, Phospholipase A2 isoform 3 Authors: Kaushik, S, Prem Kumar, R, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. Deposit date: 2010-06-18 Release date: 2010-07-14 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Crystal structure of the complex of group I phospholipase A2 with 4-Methoxy-benzoicacid at 1.4A resolution To be Published
7DLN	Structure of lysozyme obtained on SSRF using serial synchrotron crystallography Descriptor: CHLORIDE ION, Lysozyme C, SODIUM ION Authors: Zhao, F.Z. Deposit date: 2020-11-28 Release date: 2021-12-01 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structure of lysozyme obtained on SSRF using serial synchrotron crystallography To Be Published
3NCL	Crystal Structure of MT-SP1 bound to Benzamidine Phosphonate Inhibitor Descriptor: FORMIC ACID, Suppressor of tumorigenicity 14 protein, phenyl (4-carbamimidoylbenzyl)phosphonate Authors: Ray, M, Brown, C, Egea, P. Deposit date: 2010-06-04 Release date: 2011-02-16 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.19 Å) Cite: Peptide length and leaving-group sterics influence potency of Peptide phosphonate protease inhibitors. Chem.Biol., 18, 2011
4E2P	Crystal Structure of a Post-tailoring Hydroxylase (HmtN) Involved in the Himastatin Biosynthesis Descriptor: Cytochrome P450 107B1 (P450CVIIB1), MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE Authors: Zhang, H.D, Chen, J, Wang, H, Huang, L, Zhang, H.J. Deposit date: 2012-03-09 Release date: 2013-03-13 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.36 Å) Cite: Crystal Structure of a Post-tailoring Hydroxylase (HmtN) Involved in the Himastatin Biosynthesis To be Published
3NKK	Trypsin in complex with fluorine containing fragment Descriptor: 3-fluoro-4-methylbenzenecarboximidamide, CALCIUM ION, Cationic trypsin, ... Authors: Schiering, N, Vulpetti, A, Dalvit, C. Deposit date: 2010-06-20 Release date: 2010-11-10 Last modified: 2017-11-08 Method: X-RAY DIFFRACTION (1.12 Å) Cite: Combined use of computational chemistry, NMR screening, and X-ray crystallography for identification and characterization of fluorophilic protein environments. Proteins, 78, 2010
7DL6	The co-crystal structure of DYRK2 with a small molecule inhibitor 18 Descriptor: Dual specificity tyrosine-phosphorylation-regulated kinase 2, [2,7-dimethoxy-9-[[(3R)-pyrrolidin-3-yl]methylsulfanyl]acridin-4-yl]methanol Authors: Wei, T, Xiao, J. Deposit date: 2020-11-26 Release date: 2021-12-01 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.648 Å) Cite: Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
3NGG	X-ray Structure of Omwaprin Descriptor: Omwaprin-a Authors: Banigan, J.R, Mandal, K, Sawaya, M.R, Thammavongsa, V, Hendrickx, A.P.A, Schneewind, O, Yeates, T.O, Kent, S.B.H. Deposit date: 2010-06-11 Release date: 2010-09-08 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.33 Å) Cite: Determination of the X-ray structure of the snake venom protein omwaprin by total chemical synthesis and racemic protein crystallography. Protein Sci., 19, 2010
6EBB	Crystal Structure of YycF homologue, crystals grown in Tris buffer Descriptor: DNA-binding response regulator Authors: Riboldi-Tunnicliffe, A, Panjikar, S, Williamson, R.M, Gabrielsen, M. Deposit date: 2018-08-06 Release date: 2019-08-14 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.022 Å) Cite: Crystal Structure of YycF homologue, crystals grown in Tris buffer To Be Published
3MTH	X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL Descriptor: 4-HYDROXY-BENZOIC ACID METHYL ESTER, CHLORIDE ION, METHYLPARABEN INSULIN, ... Authors: Whittingham, J.L, Dodson, E.J, Moody, P.C.E, Dodson, G.G. Deposit date: 1995-09-13 Release date: 1996-01-29 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.9 Å) Cite: X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol. Biochemistry, 34, 1995
3NNN	BeF3 Activated DrrD Receiver Domain Descriptor: BERYLLIUM TRIFLUORIDE ION, DNA BINDING RESPONSE REGULATOR D, MAGNESIUM ION Authors: Robinson, V.L, Stock, A.M. Deposit date: 2010-06-23 Release date: 2010-08-11 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Regulation of response regulator autophosphorylation through interdomain contacts. J.Biol.Chem., 285, 2010
4E7V	The structure of R6 bovine insulin Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ... Authors: Harris, P, Frankaer, C.G, Knudsen, M.V. Deposit date: 2012-03-19 Release date: 2012-04-04 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy. Acta Crystallogr.,Sect.D, 68, 2012
6EHZ	NMR solution structure of murine CXCL12 gamma isoform Descriptor: Stromal cell-derived factor 1 Authors: Laguri, C, Lortat-Jacob, H, SImorre, J.P. Deposit date: 2017-09-15 Release date: 2018-10-10 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Deciphering the structural attributes of protein-heparan sulfate interactions using chemo-enzymatic approaches and NMR spectroscopy Glycobiology, 2021
6EW4	Human myelin protein P2 F57A mutant, monoclinic crystal form Descriptor: Myelin P2 protein, PALMITIC ACID Authors: Laulumaa, S, Lehtimaki, M, Kursula, P. Deposit date: 2017-11-03 Release date: 2018-07-11 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.271 Å) Cite: Structure and dynamics of a human myelin protein P2 portal region mutant indicate opening of the beta barrel in fatty acid binding proteins. BMC Struct. Biol., 18, 2018
4E7P	Crystal structure of receiver domain of putative NarL family response regulator spr1814 from Streptococcus pneumoniae in the presence of the phosphoryl analog beryllofluoride Descriptor: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Response regulator Authors: Park, A.K, Moon, J.H, Lee, K.S, Chi, Y.M. Deposit date: 2012-03-18 Release date: 2012-05-23 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.892 Å) Cite: Crystal structure of receiver domain of putative NarL family response regulator spr1814 from Streptococcus pneumoniae in the absence and presence of the phosphoryl analog beryllofluoride. Biochem.Biophys.Res.Commun., 421, 2012
4E7Z	Myosin VI (MD) pre-powerstroke state, P21 crystal form Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... Authors: Isabet, T, Sweeney, H.L, Houdusse, A. Deposit date: 2012-03-19 Release date: 2012-09-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin VI. Mol.Cell, 48, 2012
3NSH	BACE-1 in complex with ELN475957 Descriptor: Beta-secretase 1, N-[(1S,2R)-1-(3,5-difluorobenzyl)-3-({1-[4-(2,2-dimethylpropyl)thiophen-2-yl]cyclopropyl}amino)-2-hydroxypropyl]acetamide Authors: Probst, G.D, Bowers, S, Sealy, J.M, Brecht, E, Yao, N. Deposit date: 2010-07-01 Release date: 2010-09-22 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: structure-activity relationship of the aryl region. Bioorg.Med.Chem.Lett., 20, 2010
7DT9	D30N HIV Protease in complex with Saquinavir Descriptor: (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, Protease Authors: Bihani, S.C, Hosur, M.V. Deposit date: 2021-01-04 Release date: 2022-01-12 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.89 Å) Cite: D30N HIV Protease in complex with Saquinavir To Be Published
3NU3	Wild Type HIV-1 Protease with Antiviral Drug Amprenavir Descriptor: CHLORIDE ION, GLYCEROL, Protease, ... Authors: Wang, Y.-F, Kovalevsky, A.Y, Weber, I.T. Deposit date: 2010-07-06 Release date: 2010-08-25 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.02 Å) Cite: Amprenavir complexes with HIV-1 protease and its drug-resistant mutants altering hydrophobic clusters. Febs J., 277, 2010
3NV6	Crystal Structure of Camphor-Bound CYP101D2 Descriptor: CAMPHOR, Cytochrome P450, DI(HYDROXYETHYL)ETHER, ... Authors: Yang, W, Bell, S.G, Wang, H, Zhou, W.H, Bartlam, M, Wong, L.L, Rao, Z. Deposit date: 2010-07-08 Release date: 2010-11-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The structure of CYP101D2 unveils a potential path for substrate entry into the active site Biochem.J., 433, 2011
3NWQ	X-ray structure of ester chemical analogue [O-Ile50,O-Ile50']HIV-1 protease complexed with MVT-101 Descriptor: N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide, protease Authors: Torbeev, V.Y, Kent, S.B.H. Deposit date: 2010-07-10 Release date: 2011-11-02 Last modified: 2018-01-24 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Protein conformational dynamics in the mechanism of HIV-1 protease catalysis. Proc.Natl.Acad.Sci.USA, 108, 2011

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