4MTZ
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![BU of 4mtz by Molmil](/molmil-images/mine/4mtz) | Structure of XIAP-BIR1 in complex with NF023 | Descriptor: | 8-({3-[({3-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl}carbamoyl)amino]benzoyl}amino)naphthalene-1,3,5-trisulfonic acid, E3 ubiquitin-protein ligase XIAP, SULFATE ION, ... | Authors: | Cossu, F, Milani, M, Grassi, S, Mastrangelo, E, Bolognesi, M. | Deposit date: | 2013-09-20 | Release date: | 2014-09-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Protein-protein interactions in nfkb pathway: novel tools to promote apoptosis in cancer therapy To be Published
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8APZ
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8AQ0
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![BU of 8aq0 by Molmil](/molmil-images/mine/8aq0) | |
5VO0
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![BU of 5vo0 by Molmil](/molmil-images/mine/5vo0) | Structure of a TRAF6-Ubc13~Ub complex | Descriptor: | POTASSIUM ION, TNF receptor-associated factor 6, Ubiquitin, ... | Authors: | Middleton, A.J, Day, C.L. | Deposit date: | 2017-05-01 | Release date: | 2017-12-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | The activity of TRAF RING homo- and heterodimers is regulated by zinc finger 1. Nat Commun, 8, 2017
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5VNZ
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![BU of 5vnz by Molmil](/molmil-images/mine/5vnz) | Structure of a TRAF6-Ubc13~Ub complex | Descriptor: | TNF receptor-associated factor 6, Ubiquitin, Ubiquitin-conjugating enzyme E2 N, ... | Authors: | Middleton, A.J, Day, C.L. | Deposit date: | 2017-05-01 | Release date: | 2017-12-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.41 Å) | Cite: | The activity of TRAF RING homo- and heterodimers is regulated by zinc finger 1. Nat Commun, 8, 2017
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2EKE
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![BU of 2eke by Molmil](/molmil-images/mine/2eke) | |
7KLZ
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![BU of 7klz by Molmil](/molmil-images/mine/7klz) | |
2XCL
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![BU of 2xcl by Molmil](/molmil-images/mine/2xcl) | |
8P7D
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![BU of 8p7d by Molmil](/molmil-images/mine/8p7d) | |
8P7B
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8P7C
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1IYM
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![BU of 1iym by Molmil](/molmil-images/mine/1iym) | RING-H2 finger domain of EL5 | Descriptor: | EL5, ZINC ION | Authors: | Katoh, E, Katoh, S, Minami, E, Yamazaki, T. | Deposit date: | 2002-08-30 | Release date: | 2003-07-22 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | High Precision NMR Structure and Function of the RING-H2 Finger Domain of EL5, a Rice Protein Whose Expression Is Increased upon Exposure to Pathogen-derived Oligosaccharides J.Biol.Chem., 278, 2003
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1J7D
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![BU of 1j7d by Molmil](/molmil-images/mine/1j7d) | Crystal Structure of hMms2-hUbc13 | Descriptor: | MMS2, UBIQUITIN-CONJUGATING ENZYME E2-17 KDA | Authors: | Moraes, T.F, Edwards, R.A, McKenna, S, Pashushok, L, Xiao, W, Glover, J.N.M, Ellison, M.J. | Deposit date: | 2001-05-16 | Release date: | 2001-08-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13. Nat.Struct.Biol., 8, 2001
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3ADE
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![BU of 3ade by Molmil](/molmil-images/mine/3ade) | Crystal Structure of Keap1 in Complex with Sequestosome-1/p62 | Descriptor: | Kelch-like ECH-associated protein 1, SULFATE ION, Sequestosome-1 | Authors: | Kurokawa, H, Yamamoto, M. | Deposit date: | 2010-01-19 | Release date: | 2010-03-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1 Nat.Cell Biol., 12, 2010
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4YZ6
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![BU of 4yz6 by Molmil](/molmil-images/mine/4yz6) | Crystal Structure of Myc3[44-238] from Arabidopsis in complex with Jaz1 peptide [200-221] | Descriptor: | Protein TIFY 10A, Transcription factor MYC3 | Authors: | Ke, J, Zhang, F, Brunzelle, J, Xu, H.E, Melcher, K, HE, S.Y. | Deposit date: | 2015-03-24 | Release date: | 2015-08-05 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling. Nature, 525, 2015
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6LQS
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7SII
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![BU of 7sii by Molmil](/molmil-images/mine/7sii) | Human STING bound to both cGAMP and 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide (Compound 53) | Descriptor: | 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide, Stimulator of interferon genes protein, cGAMP | Authors: | Lu, D, Shang, G, Jie, L, Lu, Y, Bai, X.C, Zhang, X. | Deposit date: | 2021-10-14 | Release date: | 2022-02-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Activation of STING by targeting a pocket in the transmembrane domain. Nature, 604, 2022
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3NOW
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![BU of 3now by Molmil](/molmil-images/mine/3now) | UNC-45 from Drosophila melanogaster | Descriptor: | UNC-45 protein, SD10334p | Authors: | Lee, C.F, Hauenstein, A.V, Fleming, J.K, Gasper, W.C, Engelke, V, Banumathi, S, Bernstein, S.I, Huxford, T. | Deposit date: | 2010-06-25 | Release date: | 2011-03-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.992 Å) | Cite: | X-ray Crystal Structure of the UCS Domain-Containing UNC-45 Myosin Chaperone from Drosophila melanogaster. Structure, 19, 2011
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1ZGU
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![BU of 1zgu by Molmil](/molmil-images/mine/1zgu) | Solution structure of the human Mms2-Ubiquitin complex | Descriptor: | Ubiquitin, Ubiquitin-conjugating enzyme E2 variant 2 | Authors: | Lewis, M.J, Saltibus, L.F, Hau, D.D, Xiao, W, Spyracopoulos, L. | Deposit date: | 2005-04-22 | Release date: | 2006-04-04 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural Basis for Non-Covalent Interaction Between Ubiquitin and the Ubiquitin Conjugating Enzyme Variant Human MMS2. J.Biomol.Nmr, 34, 2006
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5G1X
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![BU of 5g1x by Molmil](/molmil-images/mine/5g1x) | Crystal structure of Aurora-A kinase in complex with N-Myc | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, AURORA KINASE A, MAGNESIUM ION, ... | Authors: | Richards, M.W, Burgess, S.G, Bayliss, R. | Deposit date: | 2016-03-31 | Release date: | 2016-11-16 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Structural Basis of N-Myc Binding by Aurora-A and its Destabilization by Kinase Inhibitors Proc.Natl.Acad.Sci.USA, 113, 2016
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3SE7
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![BU of 3se7 by Molmil](/molmil-images/mine/3se7) | ancient VanA | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, VanA | Authors: | Wright, G.D, Morar, M. | Deposit date: | 2011-06-10 | Release date: | 2011-09-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.07 Å) | Cite: | Antibiotic resistance is ancient. Nature, 477, 2011
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3LRV
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![BU of 3lrv by Molmil](/molmil-images/mine/3lrv) | |
2VRR
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![BU of 2vrr by Molmil](/molmil-images/mine/2vrr) | Structure of SUMO modified Ubc9 | Descriptor: | FORMIC ACID, SMALL UBIQUITIN-RELATED MODIFIER 1, SODIUM ION, ... | Authors: | Knipscheer, P, Flotho, A, Klug, H, Olsen, J.V, van Dijk, W.J, Fish, A, Johnson, E.S, Mann, M, Sixma, T.K, Pichler, A. | Deposit date: | 2008-04-13 | Release date: | 2008-08-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Ubc9 sumoylation regulates SUMO target discrimination. Mol. Cell, 31, 2008
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5T0Q
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![BU of 5t0q by Molmil](/molmil-images/mine/5t0q) | Crystal structure of the Myc3 N-terminal domain [44-242] in complex with JAZ10 Jas domain [166-192] from arabidopsis | Descriptor: | Protein TIFY 9, Transcription factor MYC3 | Authors: | Ke, J, Zhang, F, Brunzelle, J.S, He, S.Y, Xu, H.E, Melcher, K. | Deposit date: | 2016-08-16 | Release date: | 2017-01-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural insights into alternative splicing-mediated desensitization of jasmonate signaling. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5T0F
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![BU of 5t0f by Molmil](/molmil-images/mine/5t0f) | Crystal structure of the Myc3 N-terminal domain [44-242] in complex with JAZ10 CMID domain [16-58] from arabidopsis | Descriptor: | Protein TIFY 9, Transcription factor MYC3 | Authors: | Ke, J, Zhang, F, Brunzelle, J.S, He, S.Y, Xu, H.E, Melcher, K. | Deposit date: | 2016-08-16 | Release date: | 2017-01-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into alternative splicing-mediated desensitization of jasmonate signaling. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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