Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

6KTL
DownloadVisualize
BU of 6ktl by Molmil
Crystal structure of scyllo-inositol dehydrogenase R178A mutant, complexed with NAD and myo-inositol, from Paracoccus laeviglucosivorans
Descriptor: 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, ACETATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Suzuki, M, Koubara, K, Takenoya, M, Fukano, K, Ito, S, Sasaki, Y, Nakamura, A, Yajima, S.
Deposit date:2019-08-28
Release date:2019-12-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Single amino acid mutation altered substrate specificity for L-glucose and inositol inscyllo-inositol dehydrogenase isolated fromParacoccus laeviglucosivorans.
Biosci.Biotechnol.Biochem., 84, 2020
6KTJ
DownloadVisualize
BU of 6ktj by Molmil
Crystal structure of scyllo-inositol dehydrogenase R178A mutant, apo-form, from Paracoccus laeviglucosivorans
Descriptor: ACETATE ION, Scyllo-inositol dehydrogenase with L-glucose dehydrogenase activity
Authors:Suzuki, M, Koubara, K, Takenoya, M, Fukano, K, Ito, S, Sasaki, Y, Nakamura, A, Yajima, S.
Deposit date:2019-08-28
Release date:2019-12-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Single amino acid mutation altered substrate specificity for L-glucose and inositol inscyllo-inositol dehydrogenase isolated fromParacoccus laeviglucosivorans.
Biosci.Biotechnol.Biochem., 84, 2020
5O7I
DownloadVisualize
BU of 5o7i by Molmil
ERK5 in complex with a pyrrole inhibitor
Descriptor: 4-(2-bromanyl-6-fluoranyl-phenyl)carbonyl-~{N}-pyridin-3-yl-1~{H}-pyrrole-2-carboxamide, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase 7
Authors:Tucker, J.A, Heptinstall, A, Myers, S.
Deposit date:2017-06-08
Release date:2018-06-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38 alpha and BRD4.
Eur.J.Med.Chem., 178, 2019
3IFK
DownloadVisualize
BU of 3ifk by Molmil
Crystal Structure Of Calcium-Saturated Calmodulin N-terminal Domain Fragment, Residues 1-90
Descriptor: CALCIUM ION, CALMODULIN
Authors:Witt, T.J, Newman, R.A, Shea, M.A.
Deposit date:2009-07-24
Release date:2009-12-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Thermodynamics and conformational change governing domain-domain interactions of calmodulin.
Methods Enzymol., 466, 2009
3ITJ
DownloadVisualize
BU of 3itj by Molmil
Crystal structure of Saccharomyces cerevisiae thioredoxin reductase 1 (Trr1)
Descriptor: CITRIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin reductase 1
Authors:Oliveira, M.A, Discola, K.F, Alves, S.V, Medrano, F.J, Guimaraes, B.G, Netto, L.E.S.
Deposit date:2009-08-28
Release date:2010-03-31
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Insights into the specificity of thioredoxin reductase-thioredoxin interactions. A structural and functional investigation of the yeast thioredoxin system.
Biochemistry, 49, 2010
1HLY
DownloadVisualize
BU of 1hly by Molmil
SOLUTION STRUCTURE OF HONGOTOXIN 1
Descriptor: HONGOTOXIN 1
Authors:Pragl, B, Koschak, A, Trieb, M, Obermair, G, Kaufmann, W.A, Gerster, U, Blanc, E, Hahn, C, Prinz, H, Schutz, G, Darbon, H, Gruber, H.J, Knaus, H.G.
Deposit date:2000-12-04
Release date:2003-09-30
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Synthesis, characterization, and application of cy-dye- and alexa-dye-labeled hongotoxin(1) analogues. The first high affinity fluorescence probes for voltage-gated K+ channels.
BIOCONJUG.CHEM., 13, 2002
2KBF
DownloadVisualize
BU of 2kbf by Molmil
solution structure of carboxyl-terminal domain of Dbp5p
Descriptor: ATP-dependent RNA helicase DBP5
Authors:Fan, J.S, Zhang, J, Yang, D.
Deposit date:2008-11-28
Release date:2009-10-13
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution and crystal structures of mRNA exporter Dbp5p and its interaction with nucleotides.
J.Mol.Biol., 388, 2009
4UBP
DownloadVisualize
BU of 4ubp by Molmil
STRUCTURE OF BACILLUS PASTEURII UREASE INHIBITED WITH ACETOHYDROXAMIC ACID AT 1.55 A RESOLUTION
Descriptor: ACETOHYDROXAMIC ACID, NICKEL (II) ION, PROTEIN (UREASE (CHAIN A)), ...
Authors:Benini, S, Rypniewski, W.R, Wilson, K.S, Ciurli, S, Mangani, S.
Deposit date:1999-02-25
Release date:2000-03-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The complex of Bacillus pasteurii urease with acetohydroxamate anion from X-ray data at 1.55 A resolution.
J.Biol.Inorg.Chem., 5, 2000
5SYQ
DownloadVisualize
BU of 5syq by Molmil
Solution structure of Aquifex aeolicus Aq1974
Descriptor: Uncharacterized protein aq_1974
Authors:Sachleben, J.R, Gawlak, G, Hoey, R.J, Liu, G, Joachimiak, A, Montelione, G.T, Koide, S, Northeast Structural Genomics Consortium (NESG), Midwest Center for Structural Genomics (MCSG)
Deposit date:2016-08-11
Release date:2016-09-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Aromatic claw: A new fold with high aromatic content that evades structural prediction.
Protein Sci., 26, 2017
3HPF
DownloadVisualize
BU of 3hpf by Molmil
Crystal structure of the mutant Y90F of divergent galactarate dehydratase from Oceanobacillus iheyensis complexed with Mg and galactarate
Descriptor: D-galactaric acid, MAGNESIUM ION, Muconate cycloisomerase
Authors:Fedorov, A.A, Fedorov, E.V, Rakus, J.F, Gerlt, J.A, Almo, S.C.
Deposit date:2009-06-04
Release date:2009-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Computation-facilitated assignment of the function in the enolase superfamily: a regiochemically distinct galactarate dehydratase from Oceanobacillus iheyensis .
Biochemistry, 48, 2009
3JBH
DownloadVisualize
BU of 3jbh by Molmil
TWO HEAVY MEROMYOSIN INTERACTING-HEADS MOTIFS FLEXIBLE DOCKED INTO TARANTULA THICK FILAMENT 3D-MAP ALLOWS IN DEPTH STUDY OF INTRA- AND INTERMOLECULAR INTERACTIONS
Descriptor: MYOSIN 2 ESSENTIAL LIGHT CHAIN STRIATED MUSCLE, MYOSIN 2 HEAVY CHAIN STRIATED MUSCLE, MYOSIN 2 REGULATORY LIGHT CHAIN STRIATED MUSCLE
Authors:Alamo, L, Qi, D, Wriggers, W, Pinto, A, Zhu, J, Bilbao, A, Gillilan, R.E, Hu, S, Padron, R.
Deposit date:2015-09-01
Release date:2016-03-09
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Conserved Intramolecular Interactions Maintain Myosin Interacting-Heads Motifs Explaining Tarantula Muscle Super-Relaxed State Structural Basis.
J. Mol. Biol., 428, 2016
2KBE
DownloadVisualize
BU of 2kbe by Molmil
solution structure of amino-terminal domain of Dbp5p
Descriptor: ATP-dependent RNA helicase DBP5
Authors:Fan, J.S, Zhang, J, Yang, D.
Deposit date:2008-11-27
Release date:2009-10-13
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution and crystal structures of mRNA exporter Dbp5p and its interaction with nucleotides.
J.Mol.Biol., 388, 2009
7EL3
DownloadVisualize
BU of 7el3 by Molmil
Crystal structure of HpaR-DNA complex from Acinetobacter baumannii
Descriptor: Chains: C, Chains: D, GLYCEROL, ...
Authors:Permsirivisarn, P, Pakotiprapha, D.
Deposit date:2021-04-07
Release date:2022-01-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mechanism of transcription regulation by Acinetobacter baumannii HpaR in the catabolism of p-hydroxyphenylacetate.
Febs J., 289, 2022
1Q02
DownloadVisualize
BU of 1q02 by Molmil
NMR structure of the UBA domain of p62 (SQSTM1)
Descriptor: sequestosome 1
Authors:Ciani, B, Layfield, R, Cavey, J.R, Sheppard, P.W, Searle, M.S.
Deposit date:2003-07-15
Release date:2003-09-30
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the Ubiquitin-associated Domain of p62 (SQSTM1) and Implications for Mutations That Cause Paget's Disease of Bone
J.Biol.Chem., 278, 2003
7WZU
DownloadVisualize
BU of 7wzu by Molmil
Crystal structure of metallo-beta-lactamase IMP-6.
Descriptor: Beta-lactamase, ZINC ION
Authors:Yamaguchi, Y, Kurosaki, H.
Deposit date:2022-02-19
Release date:2023-01-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.954 Å)
Cite:Difference in the Inhibitory Effect of Thiol Compounds and Demetallation Rates from the Zn(II) Active Site of Metallo-beta-lactamases (IMP-1 and IMP-6) Associated with a Single Amino Acid Substitution.
Acs Infect Dis., 9, 2023
2PDG
DownloadVisualize
BU of 2pdg by Molmil
Human aldose reductase with uracil-type inhibitor at 1.42A.
Descriptor: Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {3-[(5-CHLORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL}ACETIC ACID
Authors:Steuber, H, Heine, A, Klebe, G.
Deposit date:2007-03-31
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features.
J.Mol.Biol., 379, 2008
2PD5
DownloadVisualize
BU of 2pd5 by Molmil
Human aldose reductase mutant V47I complexed with zopolrestat
Descriptor: 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Steuber, H, Heine, A, Klebe, G.
Deposit date:2007-03-31
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features.
J.Mol.Biol., 379, 2008
2W3B
DownloadVisualize
BU of 2w3b by Molmil
HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND A LIPOPHILIC ANTIFOLATE SELECTIVE FOR MYCOBACTERIUM AVIUM DHFR, 6-((2,5- DIETHOXYPHENYL)AMINOMETHYL)-2,4-DIAMINO-5-METHYLPYRIDO(2,3-D) PYRIMIDINE (SRI-8686)
Descriptor: 6-{[(2,5-DIETHOXYPHENYL)AMINO]METHYL}-5-METHYLPYRIDO[2,3-D]PYRIMIDINE-2,4-DIAMINE, DIHYDROFOLATE REDUCTASE, FOLIC ACID, ...
Authors:Leung, A.K.W, Reynolds, R.C, Borhani, D.W.
Deposit date:2008-11-11
Release date:2009-11-17
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Structural Basis for Selective Inhibition of Mycobacterium Avium Dihydrofolate Reductase by a Lipophilic Antifolate
To be Published
4FKD
DownloadVisualize
BU of 4fkd by Molmil
Identification of the Activator Binding Residues in the Second Cysteine-Rich Regulatory Domain of Protein Kinase C Theta
Descriptor: Protein kinase C theta type, ZINC ION
Authors:Rahman, G.M, Shanker, S, Lewin, N.E, Prasad, B.V.V, Blumberg, P.M, Das, J.
Deposit date:2012-06-13
Release date:2013-01-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.633 Å)
Cite:Identification of the Activator Binding Residues in the Second Cysteine-Rich Regulatory Domain of Protein Kinase C Theta.
Biochem.J., 451, 2013
2PDM
DownloadVisualize
BU of 2pdm by Molmil
Human aldose reductase mutant S302R complexed with zopolrestat.
Descriptor: 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Steuber, H, Heine, A, Klebe, G.
Deposit date:2007-04-01
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features.
J.Mol.Biol., 379, 2008
2PDQ
DownloadVisualize
BU of 2pdq by Molmil
Human aldose reductase mutant C303D complexed with uracil-type inhibitor.
Descriptor: Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {3-[(5-CHLORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL}ACETIC ACID
Authors:Steuber, H, Heine, A, Klebe, G.
Deposit date:2007-04-01
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features.
J.Mol.Biol., 379, 2008
4I5K
DownloadVisualize
BU of 4i5k by Molmil
PP2A PR70 Holoenzyme model3_diCa_rcsb.pdb bppnat5_extend.mtz
Descriptor: CALCIUM ION, Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
Authors:Xing, Y, Jeffrey, P.D, Shi, Y.
Deposit date:2012-11-28
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation.
Cell Res., 23, 2013
2W3A
DownloadVisualize
BU of 2w3a by Molmil
HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND TRIMETHOPRIM
Descriptor: DIHYDROFOLATE REDUCTASE, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Leung, A.K.W, Reynolds, R.C, Borhani, D.W.
Deposit date:2008-11-10
Release date:2009-11-17
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis for Selective Inhibition of Mycobacterium Avium Dihydrofolate Reductase by a Lipophilic Antifolate
To be Published
5TI8
DownloadVisualize
BU of 5ti8 by Molmil
Crystal Structure of an aspartate aminotransferase from Pseudomonas
Descriptor: Aminotransferase, CALCIUM ION
Authors:Peat, T.S, Newman, J.
Deposit date:2016-10-01
Release date:2017-01-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Crystal structure of a putrescine aminotransferase from Pseudomonas sp. strain AAC.
Acta Crystallogr F Struct Biol Commun, 73, 2017
1GK6
DownloadVisualize
BU of 1gk6 by Molmil
Human vimentin coil 2B fragment linked to GCN4 leucine zipper (Z2B)
Descriptor: VIMENTIN
Authors:Strelkov, S.V, Herrmann, H, Geisler, N, Zimbelmann, R, Aebi, U, Burkhard, P.
Deposit date:2001-08-08
Release date:2002-03-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conserved Segments 1A and 2B of the Intermediate Filament Dimer: Their Atomic Structures and Role in Filament Assembly.
Embo J., 21, 2002

243531

PDB entries from 2025-10-22

PDB statisticsPDBj update infoContact PDBjnumon