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2ZNT
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BU of 2znt by Molmil
Crystal structure of the ligand-binding core of the human ionotropic glutamate receptor, GluR5, in complex with a novel selective agonist, dysiherbaine
Descriptor: (2R,3aR,6S,7R,7aR)-2-[(2S)-2-amino-2-carboxyethyl]-6-hydroxy-7-(methylamino)hexahydro-2H-furo[3,2-b]pyran-2-carboxylic acid, BETA-MERCAPTOETHANOL, Glutamate receptor, ...
Authors:Unno, M, Sasaki, M, Ikeda-Saito, M.
Deposit date:2008-05-01
Release date:2009-05-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Binding and Selectivity of the Marine Toxin Neodysiherbaine A and Its Synthetic Analogues to GluK1 and GluK2 Kainate Receptors.
J.Mol.Biol., 413, 2011
2YV9
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BU of 2yv9 by Molmil
Crystal structure of the CLIC homologue EXC-4 from c. elegans
Descriptor: CALCIUM ION, Chloride intracellular channel exc-4
Authors:Harrop, S.J, Littler, D.R, Curmi, P.M.G.
Deposit date:2007-04-10
Release date:2008-02-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Comparison of vertebrate and invertebrate CLIC proteins: The crystal structures of Caenorhabditis elegans EXC-4 and Drosophila melanogaster DmCLIC
Proteins, 71, 2007
2YKR
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30S ribosomal subunit with RsgA bound in the presence of GMPPNP
Descriptor: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Guo, Q, Yuan, Y, Xu, Y, Feng, B, Liu, L, Chen, K, Lei, J, Gao, N.
Deposit date:2011-05-30
Release date:2011-08-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Structural Basis for the Function of a Small Gtpase Rsga on the 30S Ribosomal Subunit Maturation Revealed by Cryoelectron Microscopy.
Proc.Natl.Acad.Sci.USA, 108, 2011
1MAA
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BU of 1maa by Molmil
MOUSE ACETYLCHOLINESTERASE CATALYTIC DOMAIN, GLYCOSYLATED PROTEIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ...
Authors:Bourne, Y, Taylor, P, Bougis, P.E, Marchot, P.
Deposit date:1998-11-04
Release date:1999-04-20
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of mouse acetylcholinesterase. A peripheral site-occluding loop in a tetrameric assembly.
J.Biol.Chem., 274, 1999
1K40
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crystal structure of the FAT domain of focal adhesion kinase
Descriptor: adhesion kinase
Authors:Hayashi, I, Vuori, K, Liddington, R.C.
Deposit date:2001-10-04
Release date:2002-02-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The focal adhesion targeting (FAT) region of focal adhesion kinase is a four-helix bundle that binds paxillin
Nat.Struct.Biol., 9, 2002
1KC4
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BU of 1kc4 by Molmil
NMR Structural Analysis of the Complex Formed Between alpha-Bungarotoxin and the Principal alpha-Neurotoxin Binding Sequence on the alpha7 Subunit of a Neuronal Nicotinic Acetylcholine Receptor
Descriptor: alpha-bungarotoxin, neuronal acetylcholine receptor protein, alpha-7 chain
Authors:Moise, L, Piserchio, A, Basus, V.J, Hawrot, E.
Deposit date:2001-11-07
Release date:2002-03-13
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:NMR structural analysis of alpha-bungarotoxin and its complex with the principal alpha-neurotoxin-binding sequence on the alpha 7 subunit of a neuronal nicotinic acetylcholine receptor.
J.Biol.Chem., 277, 2002
2YFH
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Structure of a Chimeric Glutamate Dehydrogenase
Descriptor: GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE
Authors:Oliveira, T, Panjikar, S, Sharkey, M.A, Carrigan, J.B, Hamza, M, Engel, P.C, Khan, A.R.
Deposit date:2011-04-05
Release date:2012-04-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.695 Å)
Cite:Crystal Structure of a Chimaeric Bacterial Glutamate Dehydrogenase.
Acta Crystallogr.,Sect.F, 72, 2016
1KL8
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NMR STRUCTURAL ANALYSIS OF THE COMPLEX FORMED BETWEEN ALPHA-BUNGAROTOXIN AND THE PRINCIPAL ALPHA-NEUROTOXIN BINDING SEQUENCE ON THE ALPHA7 SUBUNIT OF A NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR
Descriptor: ALPHA-BUNGAROTOXIN, NEURONAL ACETYLCHOLINE RECEPTOR PROTEIN, ALPHA-7 CHAIN
Authors:Moise, L, Piserchio, A, Basus, V.J, Hawrot, E.
Deposit date:2001-12-11
Release date:2002-03-13
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:NMR structural analysis of alpha-bungarotoxin and its complex with the principal alpha-neurotoxin-binding sequence on the alpha 7 subunit of a neuronal nicotinic acetylcholine receptor.
J.Biol.Chem., 277, 2002
1IHC
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BU of 1ihc by Molmil
X-ray Structure of Gephyrin N-terminal Domain
Descriptor: Gephyrin
Authors:Sola, M, Kneussel, M, Heck, I.S, Betz, H, Weissenhorn, W.
Deposit date:2001-04-21
Release date:2001-05-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray crystal structure of the trimeric N-terminal domain of gephyrin.
J.Biol.Chem., 276, 2001
1ITU
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BU of 1itu by Molmil
HUMAN RENAL DIPEPTIDASE COMPLEXED WITH CILASTATIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CILASTATIN, RENAL DIPEPTIDASE, ...
Authors:Nitanai, Y, Satow, Y, Adachi, H, Tsujimoto, M.
Deposit date:2002-02-03
Release date:2002-08-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Human Renal Dipeptidase Involved in beta-Lactam Hydrolysis
J.Mol.Biol., 321, 2002
1IDH
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THE NMR SOLUTION STRUCTURE OF THE COMPLEX FORMED BETWEEN ALPHA-BUNGAROTOXIN AND AN 18MER COGNATE PEPTIDE
Descriptor: ACETYLCHOLINE RECEPTOR PROTEIN, ALPHA CHAIN, ALPHA-BUNGAROTOXIN
Authors:Zeng, H, Moise, L, Grant, M.A, Hawrot, E.
Deposit date:2001-04-04
Release date:2001-04-25
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:The solution structure of the complex formed between alpha-bungarotoxin and an 18-mer cognate peptide derived from the alpha 1 subunit of the nicotinic acetylcholine receptor from Torpedo californica.
J.Biol.Chem., 276, 2001
3AG3
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Bovine Heart Cytochrome c Oxidase in the Nitric Oxide-bound Fully Reduced State at 100 K
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Muramoto, K, Ohta, K, Shinzawa-Itoh, K, Kanda, K, Taniguchi, M, Nabekura, H, Yamashita, E, Tsukihara, T, Yoshikawa, S.
Deposit date:2010-03-19
Release date:2010-04-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Bovine cytochrome c oxidase structures enable O2 reduction with minimization of reactive oxygens and provide a proton-pumping gate
Proc.Natl.Acad.Sci.USA, 107, 2010
1IM3
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BU of 1im3 by Molmil
Crystal Structure of the human cytomegalovirus protein US2 bound to the MHC class I molecule HLA-A2/tax
Descriptor: HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, Human T-cell lymphotropic virus type 1 Tax peptide, ...
Authors:Gewurz, B.E, Gaudet, R, Tortorella, D, Wang, E.W, Ploegh, H.L, Wiley, D.C.
Deposit date:2001-05-09
Release date:2001-06-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2.
Proc.Natl.Acad.Sci.USA, 98, 2001
1ORV
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BU of 1orv by Molmil
Crystal Structure of Porcine Dipeptidyl Peptidase IV (CD26)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ...
Authors:Engel, M, Hoffmann, T, Wagner, L, Wermann, M, Heiser, U, Kiefersauer, R, Huber, R, Bode, W, Demuth, H.U, Brandstetter, H.
Deposit date:2003-03-16
Release date:2003-05-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structure of Dipeptidyl Peptidase IV (CD26) Reveals its Functional Regulation and Enzymatic Mechanism
Proc.Natl.Acad.Sci.USA, 100, 2003
1OW8
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Paxillin LD2 motif bound to the Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase
Descriptor: Focal adhesion kinase 1, Paxillin
Authors:Hoellerer, M.K, Noble, M.E.M, Labesse, G, Werner, J.M, Arold, S.T.
Deposit date:2003-03-28
Release date:2003-10-21
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Molecular Recognition of Paxillin LD Motifs by the Focal Adhesion Targeting Domain
Structure, 11, 2003
1MP8
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BU of 1mp8 by Molmil
Crystal structure of Focal Adhesion Kinase (FAK)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, focal adhesion kinase 1
Authors:Nowakowski, J, Cronin, C.N, McRee, D.E, Knuth, M.W, Nelson, C.G, Pavletich, N.P, Rodgers, J, Sang, B.-C, Scheibe, D.N, Swanson, R.V, Thompson, D.A.
Deposit date:2002-09-11
Release date:2003-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography
Structure, 10, 2002
1G0Y
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BU of 1g0y by Molmil
IL-1 RECEPTOR TYPE 1 COMPLEXED WITH ANTAGONIST PEPTIDE AF10847
Descriptor: ANTAGONIST PEPTIDE AF10847, INTERLEUKIN-1 RECEPTOR, TYPE I
Authors:Vigers, G.P.A, Dripps, D.J, Edwards, C.K, Brandhuber, B.J.
Deposit date:2000-10-09
Release date:2000-10-25
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray crystal structure of a small antagonist peptide bound to interleukin-1 receptor type 1.
J.Biol.Chem., 275, 2000
1KFT
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BU of 1kft by Molmil
Solution Structure of the C-Terminal domain of UvrC from E-coli
Descriptor: Excinuclease ABC subunit C
Authors:Singh, S, Folkers, G.E, Bonvin, A.M.J.J, Boelens, R, Wechselberger, R, Niztayev, A, Kaptein, R.
Deposit date:2001-11-23
Release date:2002-11-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure and DNA-binding properties of the C-terminal domain of UvrC from E.coli
EMBO J., 21, 2002
1K04
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BU of 1k04 by Molmil
Crystal Structure of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase
Descriptor: CHLORIDE ION, FOCAL ADHESION KINASE 1
Authors:Arold, S.T, Hoellerer, M.K, Noble, M.E.M.
Deposit date:2001-09-18
Release date:2002-01-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The structural basis of localization and signaling by the focal adhesion targeting domain.
Structure, 10, 2002
1LXH
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BU of 1lxh by Molmil
Solution structure of alpha-cobratoxin complexed with a cognate peptide (minimized average structure)
Descriptor: ACETYLCHOLINE RECEPTOR PROTEIN, ALPHA CHAIN, LONG NEUROTOXIN 1
Authors:Zeng, H, Hawrot, E.
Deposit date:2002-06-05
Release date:2002-11-20
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:NMR-based Binding Screen and Structural Analysis of the Complex Formed between alpha-Cobratoxin and an 18-mer Cognate Peptide Derived from the alpha1 Subunit of the Nicotinic Acetylcholine Receptor from Torpedo californica
J.Biol.Chem., 277, 2002
3A5L
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Crystal Structure of a Dictyostelium P109A Mg2+-Actin in Complex with Human Gelsolin Segment 1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Gelsolin, ...
Authors:Murakami, K, Yasunaga, T, Noguchi, T.Q, Uyeda, T.Q, Wakabayashi, T.
Deposit date:2009-08-09
Release date:2010-10-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release
Cell(Cambridge,Mass.), 143, 2010
1MZC
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Co-Crystal Structure Of Human Farnesyltransferase With Farnesyldiphosphate and Inhibitor Compound 33a
Descriptor: 2-[3-(3-ETHYL-1-METHYL-2-OXO-AZEPAN-3-YL)-PHENOXY]-4-[1-AMINO-1-(1-METHYL-1H-IMIDIZOL-5-YL)-ETHYL]-BENZONITRILE, FARNESYL DIPHOSPHATE, Protein Farnesyltransferase alpha Subunit, ...
Authors:deSolms, S.J, Ciccarone, T.M, MacTough, S.C, Shaw, A.W, Buser, C.A, Ellis-Hutchings, M, Fernandes, C, Hamilton, K.A, Huber, H.E, Kohl, N.E, Lobell, R.B, Robinson, R.G, Tsou, N.N, Walsh, E.S, Graham, S.L, Beese, L.S, Taylor, J.S.
Deposit date:2002-10-07
Release date:2003-07-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Dual Protein Farnesyltransferase-Geranylgeranyltransferase-I Inhibitors as Potential Cancer Chemotherapeutic Agents.
J.Med.Chem., 46, 2003
1MQZ
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NMR solution structure of type-B lantibiotics mersacidin bound to lipid II in DPC micelles
Descriptor: LANTIBIOTIC MERSACIDIN
Authors:Hsu, S.-T, Breukink, E, Bierbaum, G, Sahl, H.-G, de Kruijff, B, Kaptein, R, van Nuland, N.A, Bonvin, A.M.
Deposit date:2002-09-17
Release date:2003-03-11
Last modified:2024-07-10
Method:SOLUTION NMR
Cite:NMR Study of Mersacidin and Lipid II Interaction in Dodecylphosphocholine Micelles. Conformational Changes are a Key to Antimicrobial Activity
J.Biol.Chem., 278, 2003
3AG4
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Bovine Heart Cytochrome c Oxidase in the Cyanide Ion-bound Fully Reduced State at 100 K
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
Authors:Muramoto, K, Ohta, K, Shinzawa-Itoh, K, Kanda, K, Taniguchi, M, Nabekura, H, Yamashita, E, Tsukihara, T, Yoshikawa, S.
Deposit date:2010-03-19
Release date:2010-04-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Bovine cytochrome c oxidase structures enable O2 reduction with minimization of reactive oxygens and provide a proton-pumping gate
Proc.Natl.Acad.Sci.USA, 107, 2010
3A5O
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Crystal Structure of a Dictyostelium P109I Ca2+-Actin in Complex with Human Gelsolin Segment 1
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Gelsolin, ...
Authors:Murakami, K, Yasunaga, T, Noguchi, T.Q, Uyeda, T.Q, Wakabayashi, T.
Deposit date:2009-08-09
Release date:2010-10-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release
Cell(Cambridge,Mass.), 143, 2010

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