7QET
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![BU of 7qet by Molmil](/molmil-images/mine/7qet) | human Connexin 26 dodecamer at 20mmHg PCO2, pH7.4 | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE | Authors: | Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J. | Deposit date: | 2021-12-03 | Release date: | 2022-03-30 | Last modified: | 2022-05-18 | Method: | ELECTRON MICROSCOPY (2.1 Å) | Cite: | Conformational changes and CO 2 -induced channel gating in connexin26. Structure, 30, 2022
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8OFN
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![BU of 8ofn by Molmil](/molmil-images/mine/8ofn) | Structure of the yellow fever virus (Asibi strain) dimeric envelope protein | Descriptor: | Envelope glycoprotein, SULFATE ION | Authors: | Covernton, E, Vaney, M.C, Barba-Spaeth, G, Rey, F.A. | Deposit date: | 2023-03-16 | Release date: | 2023-08-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.48 Å) | Cite: | New insight into flavivirus maturation from structure/function studies of the yellow fever virus envelope protein complex. Mbio, 14, 2023
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3LYA
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![BU of 3lya by Molmil](/molmil-images/mine/3lya) | |
4JS5
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![BU of 4js5 by Molmil](/molmil-images/mine/4js5) | |
3MAT
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![BU of 3mat by Molmil](/molmil-images/mine/3mat) | E.COLI METHIONINE AMINOPEPTIDASE TRANSITION-STATE INHIBITOR COMPLEX | Descriptor: | COBALT (II) ION, METHIONINE AMINOPEPTIDASE, SODIUM ION, ... | Authors: | Lowther, W.T, Orville, A.M, Madden, D.T, Lim, S, Rich, D.H, Matthews, B.W. | Deposit date: | 1999-03-29 | Release date: | 1999-06-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis. Biochemistry, 38, 1999
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7QQE
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![BU of 7qqe by Molmil](/molmil-images/mine/7qqe) | Nuclear factor one X - NFIX in P41212 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Nuclear factor 1 X-type, ZINC ION | Authors: | Lapi, M, Chaves-Sanjuan, A, Gourlay, L.J, Tiberi, M, Polentarutti, M, Demitri, N, Bais, G, Nardini, M. | Deposit date: | 2022-01-07 | Release date: | 2023-01-18 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Nuclear factor one X - NFIX in P41212 To Be Published
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4K7C
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![BU of 4k7c by Molmil](/molmil-images/mine/4k7c) | |
3NEC
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![BU of 3nec by Molmil](/molmil-images/mine/3nec) | Crystal Structure of Toxoplasma gondii Profilin | Descriptor: | (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, Inflammatory profilin, SULFATE ION | Authors: | Kucera, K, Modis, Y. | Deposit date: | 2010-06-08 | Release date: | 2010-09-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure-based analysis of Toxoplasma gondii profilin: a parasite-specific motif is required for recognition by Toll-like receptor 11. J.Mol.Biol., 403, 2010
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7YNF
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![BU of 7ynf by Molmil](/molmil-images/mine/7ynf) | CCA-bound alpha-synuclein fibrils | Descriptor: | Alpha-synuclein, copper;trisodium;18-(2-carboxylatoethyl)-20-(carboxylatomethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18-dihydroporphyrin-21,23-diide-2-carboxylate | Authors: | Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. | Deposit date: | 2022-07-30 | Release date: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | CCA-bound alpha-synuclein fibrils To Be Published
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7ZJR
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![BU of 7zjr by Molmil](/molmil-images/mine/7zjr) | |
8A9L
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![BU of 8a9l by Molmil](/molmil-images/mine/8a9l) | Cryo-EM structure of alpha-synuclein filaments from Parkinson's disease and dementia with Lewy bodies | Descriptor: | Alpha-synuclein, Unknown fragment | Authors: | Yang, Y, Shi, Y, Schweighauser, M, Zhang, X.J, Kotecha, A, Murzin, A.G, Garringer, H.J, Cullinane, P, Saito, Y, Foroud, T, Warner, T.T, Hasegawa, K, Vidal, R, Murayama, S, Revesz, T, Ghetti, B, Hasegawa, M, Lashley, T, Scheres, H.W.S, Goedert, M. | Deposit date: | 2022-06-28 | Release date: | 2022-08-31 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Structures of alpha-synuclein filaments from human brains with Lewy pathology. Nature, 610, 2022
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8ADW
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![BU of 8adw by Molmil](/molmil-images/mine/8adw) | Lipidic alpha-synuclein fibril - polymorph L1C | Descriptor: | Alpha-synuclein | Authors: | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | Deposit date: | 2022-07-11 | Release date: | 2022-10-12 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
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8ADU
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![BU of 8adu by Molmil](/molmil-images/mine/8adu) | Lipidic alpha-synuclein fibril - polymorph L1A | Descriptor: | Alpha-synuclein | Authors: | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | Deposit date: | 2022-07-11 | Release date: | 2022-10-12 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
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3GHG
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![BU of 3ghg by Molmil](/molmil-images/mine/3ghg) | Crystal Structure of Human Fibrinogen | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A knob, B knob, ... | Authors: | Doolittle, R.F, Kollman, J.M, Sawaya, M.R, Pandi, L, Riley, M. | Deposit date: | 2009-03-03 | Release date: | 2009-05-19 | Last modified: | 2023-05-03 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of human fibrinogen. Biochemistry, 48, 2009
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8AEX
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![BU of 8aex by Molmil](/molmil-images/mine/8aex) | Lipidic alpha-synuclein fibril - polymorph L3A | Descriptor: | Alpha-synuclein | Authors: | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | Deposit date: | 2022-07-14 | Release date: | 2022-10-12 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
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8ADV
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![BU of 8adv by Molmil](/molmil-images/mine/8adv) | Lipidic alpha-synuclein fibril - polymorph L1B | Descriptor: | Alpha-synuclein | Authors: | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | Deposit date: | 2022-07-11 | Release date: | 2022-10-12 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
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8ADS
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![BU of 8ads by Molmil](/molmil-images/mine/8ads) | Lipidic alpha-synuclein fibril - polymorph L2B | Descriptor: | Alpha-synuclein | Authors: | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | Deposit date: | 2022-07-11 | Release date: | 2022-10-12 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
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3S9A
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8BQW
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![BU of 8bqw by Molmil](/molmil-images/mine/8bqw) | Cryo-EM structure of alpha-synuclein filaments doublet from Juvenile-onset synucleinopathy | Descriptor: | Alpha-synuclein, Unknown protein | Authors: | Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Peak-Chew, S.Y, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M. | Deposit date: | 2023-01-18 | Release date: | 2023-02-22 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy. Acta Neuropathol, 145, 2023
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8BQV
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![BU of 8bqv by Molmil](/molmil-images/mine/8bqv) | Cryo-EM structure of alpha-synuclein singlet filament from Juvenile-onset synucleinopathy | Descriptor: | Alpha-synuclein, Unknown protein | Authors: | Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Peak-Chew, S.Y, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M. | Deposit date: | 2023-01-18 | Release date: | 2023-02-22 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2 Å) | Cite: | New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy. Acta Neuropathol, 145, 2023
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8A4L
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![BU of 8a4l by Molmil](/molmil-images/mine/8a4l) | Lipidic alpha-synuclein fibril - polymorph L2A | Descriptor: | Alpha-synuclein | Authors: | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | Deposit date: | 2022-06-12 | Release date: | 2022-08-17 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
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3WC5
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![BU of 3wc5 by Molmil](/molmil-images/mine/3wc5) | Carboxypeptidase B in complex with DD9 | Descriptor: | (2R)-7-amino-2-(selanylmethyl)heptanoic acid, CACODYLATE ION, Carboxypeptidase B, ... | Authors: | Yoshimoto, N, Itoh, T, Inaba, Y, Yamamoto, K. | Deposit date: | 2013-05-24 | Release date: | 2013-10-02 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for inhibition of carboxypeptidase B by selenium-containing inhibitor: selenium coordinates to zinc in enzyme. J.Med.Chem., 56, 2013
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3WC7
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![BU of 3wc7 by Molmil](/molmil-images/mine/3wc7) | Carboxypeptidase B in complex with EF6265 | Descriptor: | (2S)-7-amino-2-{[(R)-hydroxy{(1R)-2-methyl-1-[(3-phenylpropanoyl)amino]propyl}phosphoryl]methyl}heptanoic acid, Carboxypeptidase B, ZINC ION | Authors: | Yoshimoto, N, Itoh, T, Inaba, Y, Yamamoto, K. | Deposit date: | 2013-05-24 | Release date: | 2013-10-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for inhibition of carboxypeptidase B by selenium-containing inhibitor: selenium coordinates to zinc in enzyme. J.Med.Chem., 56, 2013
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3WAB
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![BU of 3wab by Molmil](/molmil-images/mine/3wab) | Carboxypeptidase B in complex with DD2 | Descriptor: | (2R)-7-amino-2-(sulfanylmethyl)heptanoic acid, CACODYLATE ION, Carboxypeptidase B, ... | Authors: | Yoshimoto, N, Itoh, T, Inaba, Y, Yamamoto, K. | Deposit date: | 2013-05-01 | Release date: | 2013-10-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.154 Å) | Cite: | Structural basis for inhibition of carboxypeptidase B by selenium-containing inhibitor: selenium coordinates to zinc in enzyme. J.Med.Chem., 56, 2013
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3WC6
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![BU of 3wc6 by Molmil](/molmil-images/mine/3wc6) | Carboxypeptidase B in complex with 2nd zinc | Descriptor: | ACETATE ION, Carboxypeptidase B, ZINC ION | Authors: | Yoshimoto, N, Itoh, T, Inaba, Y, Yamamoto, K. | Deposit date: | 2013-05-24 | Release date: | 2013-10-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural basis for inhibition of carboxypeptidase B by selenium-containing inhibitor: selenium coordinates to zinc in enzyme. J.Med.Chem., 56, 2013
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