4KUB
 
 | | Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with CoA | | Descriptor: | 1,2-ETHANEDIOL, COENZYME A, GNAT superfamily acetyltransferase PA4794, ... | | Authors: | Majorek, K.A, Chruszcz, M, Osinski, T, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2013-05-21 | | Release date: | 2013-06-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa.
J.Biol.Chem., 288, 2013
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6J3P
 | | Crystal structure of the human GCN5 bromodomain in complex with compound (R,R)-36n | | Descriptor: | 2-{[(3R,5R)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methylpiperidin-3-yl]amino}-3-methyl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, Histone acetyltransferase KAT2A | | Authors: | Huang, L.Y, Li, H, Niu, L, Wu, C.Y, Yu, Y.M, Li, L.L, Yang, S.Y. | | Deposit date: | 2019-01-05 | | Release date: | 2019-05-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.598 Å) | | Cite: | Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain.
J.Med.Chem., 62, 2019
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5TRL
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5TRM
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1B87
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8HEH
 | | Crystal structure of GCN5-related N-acetyltransferase 05790 | | Descriptor: | COENZYME A, GLYCEROL, GNAT family N-acetyltransferase | | Authors: | Xu, M.X, Ran, T.T, Wang, W. | | Deposit date: | 2022-11-08 | | Release date: | 2022-12-21 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal structure of prodigiosin binding protein PgbP, a GNAT family protein, in Serratia marcescens FS14.
Biochem.Biophys.Res.Commun., 640, 2022
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9EVR
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9F5Q
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9EVQ
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1N71
 | | Crystal structure of aminoglycoside 6'-acetyltransferase type Ii in complex with coenzyme A | | Descriptor: | COENZYME A, SULFATE ION, aac(6')-Ii | | Authors: | Burk, D.L, Ghuman, N, Wybenga-Groot, L.E, Berghuis, A.M. | | Deposit date: | 2002-11-12 | | Release date: | 2003-03-18 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | X-ray structure of the AAC(6')-Ii antibiotic resistance enzyme at 1.8 A resolution; examination of oligomeric arrangements in GNAT superfamily members
Protein Sci., 12, 2003
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3KJL
 | | Sgf11:Sus1 complex | | Descriptor: | Protein SUS1, SAGA-associated factor 11 | | Authors: | Stewart, M, Ellisdon, A.M. | | Deposit date: | 2009-11-03 | | Release date: | 2009-12-08 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis for the interaction between yeast Spt-Ada-Gcn5 acetyltransferase (SAGA) complex components Sgf11 and Sus1.
J.Biol.Chem., 285, 2010
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3KIK
 | | Sgf11:Sus1 complex | | Descriptor: | Protein SUS1, SAGA-associated factor 11 | | Authors: | Stewart, M, Ellisdon, A.M. | | Deposit date: | 2009-11-02 | | Release date: | 2009-12-08 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis for the interaction between yeast Spt-Ada-Gcn5 acetyltransferase (SAGA) complex components Sgf11 and Sus1
J.Biol.Chem., 285, 2010
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7N1L
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6GTS
 | | Structure of the AtaT-AtaR complex bound DNA | | Descriptor: | Acetyltransferase, DNA, DUF1778 domain-containing protein | | Authors: | Garcia-Pino, A, Jurenas, D. | | Deposit date: | 2018-06-19 | | Release date: | 2019-03-06 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (3.357 Å) | | Cite: | Mechanism of regulation and neutralization of the AtaR-AtaT toxin-antitoxin system.
Nat. Chem. Biol., 15, 2019
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4LDF
 | | Crystal Structure of CpBRD2 from cryptosporidium, cgd3_3190 | | Descriptor: | GCN5 like acetylase + bromodomain, GLYCEROL, UNKNOWN ATOM OR ION | | Authors: | Wernimont, A.K, Loppnau, P, Fonseca, M, Knapp, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Mottaghi, K, Structural Genomics Consortium (SGC) | | Deposit date: | 2013-06-24 | | Release date: | 2013-07-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of CpBRD2 from cryptosporidium, cgd3_3190
TO BE PUBLISHED
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2VZY
 | | Crystal structure of Rv0802c from Mycobacterium tuberculosis in an unliganded form. | | Descriptor: | 2-ETHOXYETHANOL, ACETATE ION, CITRATE ANION, ... | | Authors: | Vetting, M.W, Errey, J.C, Blanchard, J.S. | | Deposit date: | 2008-08-07 | | Release date: | 2009-04-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Rv0802C from Mycobacterium Tuberculosis: The First Structure of a Succinyltransferase with the Gnat Fold.
Acta Crystallogr.,Sect.F, 64, 2008
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5JQ4
 | | Structure of a GNAT acetyltransferase SACOL1063 from Staphylococcus aureus | | Descriptor: | 1,2-ETHANEDIOL, Acetyltransferase SACOL1063, CHLORIDE ION, ... | | Authors: | Majorek, K.A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2016-05-04 | | Release date: | 2016-06-29 | | Last modified: | 2022-04-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Insight into the 3D structure and substrate specificity of previously uncharacterized GNAT superfamily acetyltransferases from pathogenic bacteria.
Biochim.Biophys.Acta, 1865, 2016
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5JPH
 | | Structure of a GNAT acetyltransferase SACOL1063 from Staphylococcus aureus in complex with CoA | | Descriptor: | Acetyltransferase SACOL1063, CHLORIDE ION, COENZYME A | | Authors: | Majorek, K.A, Osinski, T, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2016-05-03 | | Release date: | 2016-06-29 | | Last modified: | 2022-04-13 | | Method: | X-RAY DIFFRACTION (1.46 Å) | | Cite: | Insight into the 3D structure and substrate specificity of previously uncharacterized GNAT superfamily acetyltransferases from pathogenic bacteria.
Biochim.Biophys.Acta, 1865, 2016
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3D7C
 | | Crystal structure of the bromodomain of human GCN5, the general control of amino-acid synthesis protein 5-like 2 | | Descriptor: | General control of amino acid synthesis protein 5-like 2 | | Authors: | Filippakopoulos, P, Eswaran, J, Picaud, S, Fedorov, O, Murray, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2008-05-21 | | Release date: | 2008-07-15 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
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2VZZ
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1KUV
 | | X-ray Crystallographic Studies of Serotonin N-acetyltransferase Catalysis and Inhibition | | Descriptor: | COA-S-ACETYL 5-BROMOTRYPTAMINE, MAGNESIUM ION, Serotonin N-acetyltransferase | | Authors: | Wolf, E, De Angelis, J, Khalil, E.M, Cole, P.A, Burley, S.K. | | Deposit date: | 2002-01-22 | | Release date: | 2002-03-22 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | X-ray crystallographic studies of serotonin N-acetyltransferase catalysis and inhibition.
J.Mol.Biol., 317, 2002
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8H66
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8H6D
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8H65
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8H6C
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