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3CBG
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Functional and Structural Characterization of a Cationdependent O-Methyltransferase from the Cyanobacterium Synechocystis Sp. Strain PCC 6803
Descriptor: (2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid, 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, MAGNESIUM ION, ...
Authors:Kopycki, J.G, Neumann, P, Stubbs, M.T.
Deposit date:2008-02-22
Release date:2008-06-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Functional and Structural Characterization of a Cation-dependent O-Methyltransferase from the Cyanobacterium Synechocystis sp. Strain PCC 6803
J.Biol.Chem., 283, 2008
2HFN
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Crystal Structures of the Synechocystis Photoreceptor Slr1694 Reveal Distinct Structural States Related to Signaling
Descriptor: FLAVIN MONONUCLEOTIDE, Synechocystis Photoreceptor (Slr1694)
Authors:Yuan, H, Anderson, S, Masuda, S, Dragnea, V, Moffat, K, Bauer, C.E.
Deposit date:2006-06-24
Release date:2006-12-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of the Synechocystis photoreceptor Slr1694 reveal distinct structural states related to signaling.
Biochemistry, 45, 2006
8B9W
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Cysteine Synthase from Trypanosoma theileri with PLP bound
Descriptor: CHLORIDE ION, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Sowerby, K.V, Pohl, E.
Deposit date:2022-10-10
Release date:2023-05-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis.
Acta Crystallogr D Struct Biol, 79, 2023
8B9M
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Cysteine Synthase from Leishmania Infantum
Descriptor: CHLORIDE ION, Cysteine synthase, GLYCEROL
Authors:Sowerby, K.V, Pohl, E.
Deposit date:2022-10-06
Release date:2023-05-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis.
Acta Crystallogr D Struct Biol, 79, 2023
1CKW
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CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR: SOLUTION STRUCTURES OF PEPTIDES BASED ON THE PHE508 REGION, THE MOST COMMON SITE OF DISEASE-CAUSING DELTA-F508 MUTATION
Descriptor: PROTEIN (CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR))
Authors:Massiah, M.A, Ko, Y.H, Pedersen, P.L, Mildvan, A.S.
Deposit date:1999-04-26
Release date:1999-05-04
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Cystic fibrosis transmembrane conductance regulator: solution structures of peptides based on the Phe508 region, the most common site of disease-causing DeltaF508 mutation.
Biochemistry, 38, 1999
1CKZ
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CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR: SOLUTION STRUCTURES OF PEPTIDES BASED ON THE PHE508 REGION, THE MOST COMMON SITE OF DISEASE-CAUSING DELTA-F508 MUTATION
Descriptor: PROTEIN (CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR))
Authors:Massiah, M.A, Ko, Y.H, Pedersen, P.L, Mildvan, A.S.
Deposit date:1999-04-26
Release date:1999-05-04
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Cystic fibrosis transmembrane conductance regulator: solution structures of peptides based on the Phe508 region, the most common site of disease-causing DeltaF508 mutation.
Biochemistry, 38, 1999
1CKY
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CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR: SOLUTION STRUCTURES OF PEPTIDES BASED ON THE PHE508 REGION, THE MOST COMMON SITE OF DISEASE-CAUSING DELTA-F508 MUTATION
Descriptor: PROTEIN (CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR))
Authors:Massiah, M.A, Ko, Y.H, Pedersen, P.L, Mildvan, A.S.
Deposit date:1999-04-26
Release date:1999-05-04
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Cystic fibrosis transmembrane conductance regulator: solution structures of peptides based on the Phe508 region, the most common site of disease-causing DeltaF508 mutation.
Biochemistry, 38, 1999
1EVB
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NMR structure of cyanobacterial toxin, phosphatase-1/-2A inhibitor
Descriptor: MICROCYSTIN-LR
Authors:Bagu, J.R, Sykes, B.D.
Deposit date:1996-02-14
Release date:1996-11-08
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Comparison of the solution structures of microcystin-LR and motuporin.
Nat.Struct.Biol., 2, 1995
1EVA
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BU of 1eva by Molmil
NMR structure of cyanobacterial toxin, phosphatase-1/-2A inhibitor
Descriptor: MICROCYSTIN-LR
Authors:Bagu, J.R, Sykes, B.D.
Deposit date:1996-02-14
Release date:1996-11-08
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Comparison of the solution structures of microcystin-LR and motuporin.
Nat.Struct.Biol., 2, 1995
4UBG
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Resting state of rat cysteine dioxygenase C93G variant
Descriptor: Cysteine dioxygenase type 1, FE (II) ION, SODIUM ION
Authors:Fellner, M, Tchesnokov, E.P, Jameson, G.N, Wilbanks, S.M.
Deposit date:2014-08-13
Release date:2014-11-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Cys-Tyr Cross-Link of Cysteine Dioxygenase Changes the Optimal pH of the Reaction without a Structural Change.
Biochemistry, 53, 2014
4XFH
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cysteine dioxygenase variant - Y157F at pH 6.2 with cysteine
Descriptor: CYSTEINE, Cysteine dioxygenase type 1, FE (III) ION
Authors:Driggers, C.M, Karplus, P.A.
Deposit date:2014-12-26
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase.
J. Mol. Biol., 428, 2016
4XF3
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cysteine dioxygenase variant - Y157F at pH 8.0 with cysteine and dithionite
Descriptor: CYSTEINE, Cysteine dioxygenase type 1, FE (III) ION
Authors:Driggers, C.M, Karplus, P.A.
Deposit date:2014-12-25
Release date:2016-04-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase.
J. Mol. Biol., 428, 2016
4XF1
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BU of 4xf1 by Molmil
cysteine dioxygenase variant - Y157F at pH 8.0 with cysteine
Descriptor: CYSTEINE, Cysteine dioxygenase type 1, FE (III) ION
Authors:Driggers, C.M, Karplus, P.A.
Deposit date:2014-12-25
Release date:2016-04-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase.
J. Mol. Biol., 428, 2016
6O13
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E. coli cysteine desulfurase SufS H123A with a Cys-ketimine intermediate
Descriptor: CHLORIDE ION, Cys-ketimine, Cysteine desulfurase
Authors:Dunkle, J.A, Frantom, P.A.
Deposit date:2019-02-17
Release date:2019-07-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.203 Å)
Cite:Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues.
J.Biol.Chem., 294, 2019
8S5I
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BU of 8s5i by Molmil
Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, basal state, single particle reconstruction
Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE
Authors:McCorvie, T.J, Yue, W.W.
Deposit date:2024-02-23
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8S5L
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BU of 8s5l by Molmil
Full-length human cystathionine beta-synthase, basal state, partially degraded tetramer
Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE, PYRIDOXAL-5'-PHOSPHATE
Authors:McCorvie, T.J, Yue, W.W.
Deposit date:2024-02-23
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8S5J
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BU of 8s5j by Molmil
Full-length human cystathionine beta-synthase, basal state, helical reconstruction
Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE
Authors:McCorvie, T.J, Yue, W.W.
Deposit date:2024-02-23
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8S5K
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BU of 8s5k by Molmil
Full-length human cystathionine beta-synthase, basal state, single particle reconstruction
Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE
Authors:McCorvie, T.J, Yue, W.W.
Deposit date:2024-02-23
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8S5H
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BU of 8s5h by Molmil
Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, basal state, helical reconstruction
Descriptor: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE
Authors:McCorvie, T.J, Yue, W.W.
Deposit date:2024-02-23
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
8S5M
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BU of 8s5m by Molmil
Full-length human cystathionine beta-synthase with C-terminal 6xHis-tag, SAM bound, activated state, helical reconstruction
Descriptor: Cystathionine beta-synthase, S-ADENOSYLMETHIONINE
Authors:McCorvie, T.J, Yue, W.W.
Deposit date:2024-02-23
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
6O11
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E. coli cysteine desulfurase SufS C364A with a Cys-aldimine intermediate
Descriptor: CHLORIDE ION, Cysteine desulfurase, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-CYSTEINE
Authors:Dunkle, J.A, Frantom, P.A.
Deposit date:2019-02-17
Release date:2019-06-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues.
J.Biol.Chem., 294, 2019
6BPR
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Crystal structure of cysteine, nitric oxide-bound ferrous form of the uncrosslinked F2-Tyr157 human cysteine dioxygenase
Descriptor: CYSTEINE, Cysteine dioxygenase type 1, FE (III) ION, ...
Authors:Liu, A, Li, J, Shin, I.
Deposit date:2017-11-26
Release date:2019-04-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Probing the Cys-Tyr Cofactor Biogenesis in Cysteine Dioxygenase by the Genetic Incorporation of Fluorotyrosine.
Biochemistry, 58, 2019
6N42
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Crystal structure of cysteine-bound ferrous form of the crosslinked human cysteine dioxygenase in the anaerobic condition
Descriptor: CYSTEINE, Cysteine dioxygenase type 1, FE (II) ION, ...
Authors:Liu, A, Li, J.
Deposit date:2018-11-16
Release date:2019-04-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Probing the Cys-Tyr Cofactor Biogenesis in Cysteine Dioxygenase by the Genetic Incorporation of Fluorotyrosine.
Biochemistry, 58, 2019
6N43
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Crystal structure of cysteine, nitric oxide-bound ferrous form of the crosslinked human cysteine dioxygenase in the anaerobic condition
Descriptor: CYSTEINE, Cysteine dioxygenase type 1, FE (III) ION, ...
Authors:Liu, A, Li, J.
Deposit date:2018-11-16
Release date:2019-04-17
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.289 Å)
Cite:Probing the Cys-Tyr Cofactor Biogenesis in Cysteine Dioxygenase by the Genetic Incorporation of Fluorotyrosine.
Biochemistry, 58, 2019
6E87
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Crystal structure of ferrous form of the crosslinked human cysteine dioxygenase in the anaerobic condition
Descriptor: Cysteine dioxygenase type 1, FE (II) ION, GLYCEROL, ...
Authors:Liu, A, Li, J.
Deposit date:2018-07-27
Release date:2019-04-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.952 Å)
Cite:Probing the Cys-Tyr Cofactor Biogenesis in Cysteine Dioxygenase by the Genetic Incorporation of Fluorotyrosine.
Biochemistry, 58, 2019

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