PDB Search results for query - Protein Data Bank Japan

PDB: 1847 results Info pages Status search Chemie search BIRD

Human PPARgamma ligand binding dmain complexed with SB1406 in a covalent bonded form
Descriptor:	N-[3-(benzyloxy)phenyl]-3-nitrobenzamide, Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma
Authors:	Jang, J.Y.
Deposit date:	2015-09-17
Release date:	2016-09-21
Method:	X-RAY DIFFRACTION (2.95 Å)
Cite:	Human PPARgamma ligand binding dmain complexed with SB1406 in a covalent bonded form To Be Published

5DRM

Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a dichloro-substituted, 2,5-diarylthiophene-core ligand 4,4'-thiene-2,5-diylbis(3-chlorophenol)
Descriptor:	4,4'-thiene-2,5-diylbis(3-chlorophenol), Estrogen receptor, Nuclear receptor coactivator 2
Authors:	Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
Deposit date:	2015-09-16
Release date:	2016-05-04
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.241 Å)
Cite:	Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016

5DRJ

Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a dichloro-substituted, 3-methyl 2,5-diarylthiophene-core ligand 4,4'-(3-methylthiene-2,5-diyl)bis(3-chlorophenol)
Descriptor:	4,4'-(3-methylthiene-2,5-diyl)bis(3-chlorophenol), Estrogen receptor, Nuclear receptor coactivator 2
Authors:	Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
Deposit date:	2015-09-15
Release date:	2016-05-04
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.07 Å)
Cite:	Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016

5DP0

Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a 4-fluorophenylamino-substituted triaryl-ethylene derivative 4,4'-(2-{3-[(4-fluorophenyl)amino]phenyl}ethene-1,1-diyl)diphenol
Descriptor:	4,4'-(2-{3-[(4-fluorophenyl)amino]phenyl}ethene-1,1-diyl)diphenol, Estrogen receptor, Nuclear receptor coactivator 2
Authors:	Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
Deposit date:	2015-09-11
Release date:	2016-05-04
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.382 Å)
Cite:	Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016

5DMF

Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a 4-fluorophenylamino-substituted, methyl triaryl-ethylene derivative 4,4'-(2-{3-[(4-fluorophenyl)amino]phenyl}prop-1-ene-1,1-diyl)diphenol
Descriptor:	4,4'-(2-{3-[(4-fluorophenyl)amino]phenyl}prop-1-ene-1,1-diyl)diphenol, Estrogen receptor, Nuclear receptor coactivator 2
Authors:	Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
Deposit date:	2015-09-08
Release date:	2016-05-04
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016

5DMC

Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a nitrile-substituted triaryl-ethylene derivative 3,3-bis(4-hydroxyphenyl)-2-phenylprop-2-enenitrile
Descriptor:	3,3-bis(4-hydroxyphenyl)-2-phenylprop-2-enenitrile, Estrogen receptor, Nuclear receptor coactivator 2
Authors:	Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
Deposit date:	2015-09-08
Release date:	2016-05-04
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.403 Å)
Cite:	Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016

5DLR

Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a triaryl-ethylene compound 4,4'-(2-phenylethene-1,1-diyl)diphenol
Descriptor:	4,4'-(2-phenylethene-1,1-diyl)diphenol, Estrogen receptor, Nuclear receptor coactivator 2
Authors:	Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
Deposit date:	2015-09-07
Release date:	2016-05-04
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.26 Å)
Cite:	Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016

5DL4

Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a phenylamino-substituted, methyl, triaryl-ethylene derivative 4,4'-{2-[3-(phenylamino)phenyl]prop-1-ene-1,1-diyl}diphenol
Descriptor:	4,4'-{2-[3-(phenylamino)phenyl]prop-1-ene-1,1-diyl}diphenol, Estrogen receptor, Nuclear receptor coactivator 2
Authors:	Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
Deposit date:	2015-09-04
Release date:	2016-05-04
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016

5DKS

Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a 2-naphthylamino-substituted, ethyl, triaryl-ethylene derivative 4,4'-{2-[3-(naphthalen-1-ylamino)phenyl]but-1-ene-1,1-diyl}diphenol
Descriptor:	4,4'-{2-[3-(naphthalen-1-ylamino)phenyl]but-1-ene-1,1-diyl}diphenol, Estrogen receptor, Nuclear receptor coactivator 2
Authors:	Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
Deposit date:	2015-09-03
Release date:	2016-05-04
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016

5DKG

Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a t-butyl-substituted, methyl, triaryl-ethylene derivative 4,4'-[2-(4-tert-butylphenyl)prop-1-ene-1,1-diyl]diphenol
Descriptor:	4,4'-[2-(4-tert-butylphenyl)prop-1-ene-1,1-diyl]diphenol, Estrogen receptor, Nuclear receptor coactivator 2
Authors:	Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
Deposit date:	2015-09-03
Release date:	2016-05-04
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.15 Å)
Cite:	Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016

5DKE

Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a 3-naphthyl-substituted, methyl, cis-diaryl-ethylene compound 4,4'-[2-(naphthalen-2-yl)prop-1-ene-1,1-diyl]diphenol
Descriptor:	4,4'-[2-(naphthalen-2-yl)prop-1-ene-1,1-diyl]diphenol, Estrogen receptor, Nuclear receptor coactivator 2
Authors:	Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
Deposit date:	2015-09-03
Release date:	2016-05-04
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016

5DKB

Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a 3-methylphenylamino-substituted ethyl triaryl-ethylene derivative 4,4'-(2-{3-[(3-methylphenyl)amino]phenyl}but-1-ene-1,1-diyl)diphenol
Descriptor:	4,4'-(2-{3-[(3-methylphenyl)amino]phenyl}but-1-ene-1,1-diyl)diphenol, Estrogen receptor, Nuclear receptor coactivator 2
Authors:	Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
Deposit date:	2015-09-03
Release date:	2016-05-04
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016

5DK9

Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a phenylamino-substituted ethyl triaryl-ethylene derivative 4,4'-{2-[3-(phenylamino)phenyl]but-1-ene-1,1-diyl}diphenol
Descriptor:	4,4'-{2-[3-(phenylamino)phenyl]but-1-ene-1,1-diyl}diphenol, Estrogen receptor, Nuclear receptor coactivator 2
Authors:	Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
Deposit date:	2015-09-03
Release date:	2016-05-04
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.28 Å)
Cite:	Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016

5DIG

Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a trifluoromethyl-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-5-[4-hydroxy-2-(trifluoromethyl)phenyl]-7a-methyloctahydro-1H-inden-1-ol
Descriptor:	(1S,3aR,5S,7aS)-5-[4-hydroxy-2-(trifluoromethyl)phenyl]-7a-methyloctahydro-1H-inden-1-ol, Estrogen receptor, Nuclear receptor coactivator 2
Authors:	Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
Deposit date:	2015-09-01
Release date:	2016-05-04
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.24 Å)
Cite:	Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016

5DIE

Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a trifluoro-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-7a-methyl-5-(2,3,5-trifluoro-4-hydroxyphenyl)octahydro-1H-inden-1-ol
Descriptor:	(1S,3aR,5S,7aS)-7a-methyl-5-(2,3,5-trifluoro-4-hydroxyphenyl)octahydro-1H-inden-1-ol, Estrogen receptor, Nuclear receptor coactivator 2
Authors:	Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
Deposit date:	2015-08-31
Release date:	2016-05-04
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.24 Å)
Cite:	Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016

5DID

Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a difluoro-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-5-(2,3-difluoro-4-hydroxyphenyl)-7a-methyloctahydro-1H-inden-1-ol
Descriptor:	(1S,3aR,5S,7aS)-5-(2,3-difluoro-4-hydroxyphenyl)-7a-methyloctahydro-1H-inden-1-ol, Estrogen receptor, Nuclear receptor coactivator 2
Authors:	Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
Deposit date:	2015-08-31
Release date:	2016-05-04
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.24 Å)
Cite:	Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016

5DI7

Crystal Structure of the ER-alpha Ligand-binding Domain in complex with an methyl-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-5-(4-hydroxy-2-methylphenyl)-7a-methyloctahydro-1H-inden-1-ol
Descriptor:	(1S,3aR,5S,7aS)-5-(4-hydroxy-2-methylphenyl)-7a-methyloctahydro-1H-inden-1-ol, Estrogen receptor, Nuclear receptor coactivator 2
Authors:	Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
Deposit date:	2015-08-31
Release date:	2016-05-04
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.241 Å)
Cite:	Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016

5CJ6

Crystal Structure of a Selective Androgen Receptor Modulator Bound to the Ligand Binding Domain of the Human Androgen Receptor
Descriptor:	2-chloro-4-{[(1R,2R)-2-hydroxy-2-methylcyclopentyl]amino}-3-methylbenzonitrile, Androgen receptor, small peptide
Authors:	Luz, J.G, Saeed, A, Wang, Y.
Deposit date:	2015-07-14
Release date:	2016-01-06
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.07 Å)
Cite:	2-Chloro-4-[[(1R,2R)-2-hydroxy-2-methyl-cyclopentyl]amino]-3-methyl-benzonitrile: A Transdermal Selective Androgen Receptor Modulator (SARM) for Muscle Atrophy. J.Med.Chem., 59, 2016

5C4U

Identification of a Novel Allosteric Binding Site for RORgt Inhibitors
Descriptor:	4-{1-[2-chloro-6-(trifluoromethyl)benzoyl]-1H-pyrazolo[4,3-b]pyridin-3-yl}-5-fluoro-2-hydroxybenzoic acid, GLYCEROL, Nuclear receptor ROR-gamma
Authors:	Parthasarathy, G, Soisson, S.
Deposit date:	2015-06-18
Release date:	2015-12-16
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.08 Å)
Cite:	Identification of an allosteric binding site for ROR gamma t inhibition. Nat Commun, 6, 2015

5C4T

Identification of a Novel Allosteric Binding Site for RORgt Inhibitors
Descriptor:	(1S)-4-{1-[2-chloro-6-(trifluoromethyl)benzoyl]-4-fluoro-1H-indazol-3-yl}-1-methylcyclohex-3-ene-1-carboxylic acid, GLYCEROL, Nuclear receptor ROR-gamma, ...
Authors:	Parthasarathy, G, Soisson, S.
Deposit date:	2015-06-18
Release date:	2015-12-16
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (1.77 Å)
Cite:	Identification of an allosteric binding site for ROR gamma t inhibition. Nat Commun, 6, 2015

5C4S

Identification of a Novel Allosteric Binding Site for RORgt Inhibitors
Descriptor:	4-{1-[2-chloro-6-(trifluoromethyl)benzoyl]-4-fluoro-1H-indazol-3-yl}-3-fluorobenzoic acid, GLYCEROL, Nuclear receptor ROR-gamma
Authors:	Parthasarathy, G, Soisson, S.
Deposit date:	2015-06-18
Release date:	2015-12-16
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.23 Å)
Cite:	Identification of an allosteric binding site for ROR gamma t inhibition. Nat Commun, 6, 2015

5C4O

Identification of a Novel Allosteric Binding Site for RORgt Inhibitors
Descriptor:	4-{1-[2-chloro-6-(trifluoromethyl)benzoyl]-1H-indazol-3-yl}benzoic acid, GLYCEROL, Nuclear receptor ROR-gamma, ...
Authors:	Parthasarathy, G, Soisson, S.
Deposit date:	2015-06-18
Release date:	2015-12-16
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.24 Å)
Cite:	Identification of an allosteric binding site for ROR gamma t inhibition. Nat Commun, 6, 2015

5B5B

Crystal structure of VDR-LBD complexed with 2-methylidene-26,27-diphenyl-19-nor-1,25-dihydroxyvitamin D3
Descriptor:	(1R,3R)-5-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-oxidanyl-7-phenyl-6-(phenylmethyl)heptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-2-methylidene-cyclohexane-1,3-diol, Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor
Authors:	Kato, A, Itoh, T, Yamamoto, K.
Deposit date:	2016-05-02
Release date:	2016-06-29
Last modified:	2024-03-20
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Helix12-Stabilization Antagonist of Vitamin D Receptor Bioconjug.Chem., 27, 2016

5B41

Crystal structure of VDR-LBD complexed with 2-methylidene-19-nor-1a,25-dihydroxyvitamin D3
Descriptor:	(1R,3R)-5-(2-((1R,3aS,7aR,E)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-2- methylenecyclohexane-1,3-diol, Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor
Authors:	Anami, Y, Itoh, T, Yamamoto, K.
Deposit date:	2016-03-23
Release date:	2016-12-07
Last modified:	2023-11-08
Method:	X-RAY DIFFRACTION (1.89 Å)
Cite:	Apo- and Antagonist-Binding Structures of Vitamin D Receptor Ligand-Binding Domain Revealed by Hybrid Approach Combining Small-Angle X-ray Scattering and Molecular Dynamics J.Med.Chem., 59, 2016

5AZV

Crystal structure of hPPARgamma ligand binding domain complexed with 17-oxoDHA
Descriptor:	(4~{Z},7~{Z},10~{Z},13~{Z},19~{Z})-17-oxidanylidenedocosa-4,7,10,13,19-pentaenoic acid, Peroxisome proliferator-activated receptor gamma
Authors:	Egawa, D, Itoh, T, Yamamoto, K.
Deposit date:	2015-10-23
Release date:	2016-07-06
Last modified:	2020-02-26
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	17-OxoDHA Is a PPAR alpha/gamma Dual Covalent Modifier and Agonist Acs Chem.Biol., 2016

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Total results:	1847
Displayed results:	25
Sorted by:	PDBID descending
Query:	PF00104