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5WLC
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BU of 5wlc by Molmil
The complete structure of the small subunit processome
Descriptor: 18S pre-rRNA, 5' ETS, Bms1, ...
Authors:Barandun, J, Chaker-Margot, M, Hunziker, M, Klinge, S.
Deposit date:2017-07-26
Release date:2017-09-27
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The complete structure of the small-subunit processome.
Nat. Struct. Mol. Biol., 24, 2017
5WDT
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BU of 5wdt by Molmil
70S ribosome-EF-Tu H84A complex with GppNHp
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Fislage, M, Brown, Z, Frank, J.
Deposit date:2017-07-06
Release date:2018-04-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5WNU
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BU of 5wnu by Molmil
Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
Descriptor: (1R,2S,3S,4R,6R)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-alpha-L-altropyranosyl)-beta-L-arabinofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-allopyranoside, 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, ...
Authors:DeMirci, H.
Deposit date:2017-08-01
Release date:2018-02-21
Last modified:2020-10-21
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation.
Nat. Struct. Mol. Biol., 25, 2018
3DYO
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BU of 3dyo by Molmil
E. coli (lacZ) beta-galactosidase (H418N) in complex with IPTG
Descriptor: 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
Authors:Juers, D.H, Huber, R.E, Matthews, B.W.
Deposit date:2008-07-28
Release date:2008-10-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Direct and indirect roles of His-418 in metal binding and in the activity of beta-galactosidase (E. coli).
Protein Sci., 18, 2009
3EU8
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BU of 3eu8 by Molmil
Crystal structure of putative glucoamylase (YP_210071.1) from Bacteroides fragilis NCTC 9343 at 2.12 A resolution
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, POTASSIUM ION, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2008-10-09
Release date:2008-10-21
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Crystal structure of putative glucoamylase (YP_210071.1) from Bacteroides fragilis NCTC 9343 at 2.12 A resolution
To be published
5J7Y
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BU of 5j7y by Molmil
Architecture of loose respirasome
Descriptor: COMPLEX I 13KDA/NDUFS6, COMPLEX I 15KDA/NDUFS5, COMPLEX I 18KDA/NDUFS6, ...
Authors:Letts, J.A, Fiedorczuk, F, Sazanov, L.A.
Deposit date:2016-04-07
Release date:2016-09-21
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:The architecture of respiratory supercomplexes.
Nature, 537, 2016
3TA4
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BU of 3ta4 by Molmil
Small laccase from Amycolatopsis sp. ATCC 39116 complexed with 1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)-1,3-dihydroxypropane
Descriptor: (1R,2S)-1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol, COPPER (II) ION, small laccase, ...
Authors:Lukk, T, Majumdar, S, Gerlt, J.A, Nair, S.K.
Deposit date:2011-08-03
Release date:2012-09-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Roles of small laccases from Streptomyces in lignin degradation.
Biochemistry, 53, 2014
5IV5
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BU of 5iv5 by Molmil
Cryo-electron microscopy structure of the hexagonal pre-attachment T4 baseplate-tail tube complex
Descriptor: Baseplate hub protein gp27, Baseplate tail-tube protein gp48, Baseplate tail-tube protein gp54, ...
Authors:Taylor, N.M.I, Guerrero-Ferreira, R.C, Goldie, K.N, Stahlberg, H, Leiman, P.G.
Deposit date:2016-03-19
Release date:2016-05-18
Last modified:2018-02-07
Method:ELECTRON MICROSCOPY (4.11 Å)
Cite:Structure of the T4 baseplate and its function in triggering sheath contraction.
Nature, 533, 2016
5EJ8
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BU of 5ej8 by Molmil
EcMenD-ThDP-Mn2+ complex structure soaked with 2-ketoglutarate for 2 min
Descriptor: (4S)-4-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3lambda~5~-thiazol-2-yl}-4-hydroxybutanoic acid, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Song, H.G, Dong, C, Chen, Y.Z, Sun, Y.R, Guo, Z.H.
Deposit date:2015-11-01
Release date:2016-06-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:A Thiamine-Dependent Enzyme Utilizes an Active Tetrahedral Intermediate in Vitamin K Biosynthesis
J.Am.Chem.Soc., 138, 2016
5EUJ
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BU of 5euj by Molmil
PYRUVATE DECARBOXYLASE FROM ZYMOBACTER PALMAE
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, Pyruvate decarboxylase, ...
Authors:Buddrus, L, Crennell, S.J, Leak, D.J, Danson, M.J, Andrews, E.S.V, Arcus, V.L.
Deposit date:2015-11-18
Release date:2016-09-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of pyruvate decarboxylase from Zymobacter palmae.
Acta Crystallogr.,Sect.F, 72, 2016
3T1Y
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BU of 3t1y by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA Lysine 3 (TRNALYS3) bound to an mRNA with an AAG-codon in the A-site and paromomycin
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Murphy, F.V, Vendeix, F.A.P, Cantara, W, Leszczynska, G, Gustilo, E.M, Sproat, B, Malkiewicz, A.A.P, Agris, P.F.
Deposit date:2011-07-22
Release date:2012-01-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Human tRNA(Lys3)(UUU) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism.
J.Mol.Biol., 416, 2012
3TBC
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BU of 3tbc by Molmil
Small laccase from Streptomyces viridosporus T7A; alternate crystal form complexed with acetovanillone.
Descriptor: 1-(4-hydroxy-3-methoxyphenyl)ethanone, COPPER (II) ION, OXYGEN MOLECULE, ...
Authors:Lukk, T, Majumdar, S, Gerlt, J.A, Nair, S.K.
Deposit date:2011-08-05
Release date:2012-08-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Roles of small laccases from Streptomyces in lignin degradation.
Biochemistry, 53, 2014
5FT8
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BU of 5ft8 by Molmil
Crystal structure of the complex between the cysteine desulfurase CsdA and the sulfur-acceptor CsdE in the persulfurated state at 2.50 Angstroem resolution
Descriptor: Cysteine desulfurase CsdA, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Fernandez, F.J, Arda, A, Lopez-Estepa, M, Aranda, J, Penya-Soler, E, Garces, F, Round, A, Campos-Oliva, R, Bruix, M, Coll, M, Tunon, I, Jimenez-Barbero, J, Vega, M.C.
Deposit date:2016-01-11
Release date:2016-11-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanism of Sulfur Transfer Across Protein-Protein Interfaces: The Cysteine Desulfurase Model System
Acs Catalysis, 6, 2016
5K09
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BU of 5k09 by Molmil
Crystal Structure of COMT in complex with a thiazole ligand
Descriptor: 5-{3-[(4-methoxyphenyl)methyl]-1H-pyrazol-5-yl}-2,4-dimethyl-1,3-thiazole, Catechol O-methyltransferase, PHOSPHATE ION, ...
Authors:Ehler, A, Rodriguez-Sarmiento, R.M, Rudolph, M.G.
Deposit date:2016-05-17
Release date:2016-09-07
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Design of Potent and Druglike Nonphenolic Inhibitors for Catechol O-Methyltransferase Derived from a Fragment Screening Approach Targeting the S-Adenosyl-l-methionine Pocket.
J. Med. Chem., 59, 2016
3T1H
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BU of 3t1h by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a human anti-codon stem loop (HASL) of transfer RNA lysine 3 (tRNALys3) bound to an mRNA with an AAA-codon in the A-site and Paromomycin
Descriptor: 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Murphy, F.V, Vendeix, F.A.P, Cantara, W, Leszczynska, G, Gustilo, E.M, Sproat, B, Malkiewicz, A.A.P, Agris, P.F.
Deposit date:2011-07-21
Release date:2012-01-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Human tRNA(Lys3)(UUU) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism.
J.Mol.Biol., 416, 2012
3HHQ
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BU of 3hhq by Molmil
Crystal structure of apo dUT1p from Saccharomyces cerevisiae
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Singer, A.U, Evdokimova, E, Kudritska, M, Dong, A, Edwards, A.M, Yakunin, A.F, Savchenko, A.
Deposit date:2009-05-15
Release date:2009-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and activity of the Saccharomyces cerevisiae dUTP pyrophosphatase DUT1, an essential housekeeping enzyme.
Biochem.J., 437, 2011
3HFA
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BU of 3hfa by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome open-gate mutant
Descriptor: DIMETHYLFORMAMIDE, Proteasome (Alpha subunit) PrcA, Proteasome (Beta subunit) PrcB
Authors:Li, D, Li, H.
Deposit date:2009-05-11
Release date:2009-09-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.504 Å)
Cite:Inhibitors selective for mycobacterial versus human proteasomes.
Nature, 461, 2009
3T6D
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BU of 3t6d by Molmil
Crystal Structure of the Reaction Centre from Blastochloris viridis strain DSM 133 (ATCC 19567) substrain-08
Descriptor: (2S,3R)-heptane-1,2,3-triol, 15-cis-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL B, ...
Authors:Roszak, A.W, Gardiner, A.T, Isaacs, N.W, Cogdell, R.J.
Deposit date:2011-07-28
Release date:2011-11-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:New insights into the structure of the reaction centre from Blastochloris viridis: evolution in the laboratory.
Biochem.J., 442, 2012
3T8W
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BU of 3t8w by Molmil
A bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases
Descriptor: CARBONATE ION, M17 leucyl aminopeptidase, N-((2R,3S,6S,18S,21S)-2-amino-18-(4-benzoylbenzyl)-21-carbamoyl-3-hydroxy-6-(naphthalen-2-ylmethyl)-4,7,16,19-tetraoxo-1-phenyl-11,14-dioxa-5,8,17,20-tetraazapentacosan-25-yl)hex-5-ynamide, ...
Authors:McGowan, S, Klemba, M, Greebaum, D.C.
Deposit date:2011-08-01
Release date:2011-09-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases
Proc.Natl.Acad.Sci.USA, 108, 2011
3TBB
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BU of 3tbb by Molmil
Small laccase from Streptomyces viridosporus T7A; alternate crystal form.
Descriptor: COPPER (II) ION, OXYGEN MOLECULE, PHOSPHATE ION, ...
Authors:Lukk, T, Majumdar, S, Gerlt, J.A, Nair, S.K.
Deposit date:2011-08-05
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Roles of small laccases from Streptomyces in lignin degradation.
Biochemistry, 53, 2014
5FVB
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BU of 5fvb by Molmil
CRYSTAL STRUCTURE OF PHORMIDIUM C-PHYCOERYTHRIN AT PH 5.0
Descriptor: C-PHYCOERYTHRIN ALPHA SUBUNIT, C-PHYCOERYTHRIN BETA SUBUNIT, GLYCEROL, ...
Authors:Kumar, V, Sonani, R.R, Sharma, M, Gupta, G.D, Madamwar, D.
Deposit date:2016-02-05
Release date:2016-06-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystal Structure Analysis of C-Phycoerythrin from Marine Cyanobacterium Phormidium Sp. A09Dm.
Photosynth.Res., 129, 2016
5GAE
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BU of 5gae by Molmil
RNC in complex with a translocating SecYEG
Descriptor: 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ...
Authors:Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N.
Deposit date:2015-11-25
Release date:2016-01-27
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon.
Nat Commun, 7, 2016
3HF9
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BU of 3hf9 by Molmil
Crystal Structure of Mycobacterium Tuberculosis Proteasome open-gate mutant modified by inhibitor GL1
Descriptor: Proteasome (Alpha subunit) PrcA, Proteasome (Beta subunit) PrcB
Authors:Li, D, Li, H.
Deposit date:2009-05-11
Release date:2009-09-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.878 Å)
Cite:Inhibitors selective for mycobacterial versus human proteasomes.
Nature, 461, 2009
5KAI
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BU of 5kai by Molmil
NH3-bound RT XFEL structure of Photosystem II 500 ms after the 2nd illumination (2F) at 2.8 A resolution
Descriptor: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
Authors:Young, I.D, Ibrahim, M, Chatterjee, R, Gul, S, Koroidov, S, Brewster, A.S, Tran, R, Alonso-Mori, R, Fuller, F, Kroll, T, Michels-Clark, T, Laksmono, H, Sierra, R.G, Stan, C.A, Saracini, C, Bean, M.A, Seuffert, I, Sokaras, D, Weng, T.-C, Hunter, M.S, Aquila, A, Koglin, J.E, Robinson, J, Liang, M, Boutet, S, Lyubimov, A.Y, Uervirojnangkoorn, M, Moriarty, N.W, Liebschner, D, Afonine, P.V, Waterman, D.G, Evans, G, Dobbek, H, Weis, W.I, Brunger, A.T, Zwart, P.H, Adams, P.D, Zouni, A, Messinger, J, Bergmann, U, Sauter, N.K, Kern, J, Yachandra, V.K, Yano, J.
Deposit date:2016-06-01
Release date:2016-11-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.80000925 Å)
Cite:Structure of photosystem II and substrate binding at room temperature.
Nature, 540, 2016
3G37
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BU of 3g37 by Molmil
Cryo-EM structure of actin filament in the presence of phosphate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Wakabayshi, T, Murakami, K, Yasunaga, T, Noguchi, T.Q, Uyeda, T.Q.
Deposit date:2009-02-02
Release date:2010-11-03
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release
Cell(Cambridge,Mass.), 143, 2010

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