5J7Y

Architecture of loose respirasome

This is a large structure.

Summary for 5J7Y

Related5J4Z
EMDB information8128
DescriptorCOMPLEX I ND3, COMPLEX I PSST/NDUFS7, COMPLEX I 30KDA/NDUFS3, ... (80 entities in total)
Functional Keywordsmitochondrial supercomplex, nadh-ubiquinone oxidoreductase, coenzyme q-cytochrome c oxidoreductase, cytochrome c oxidase, respirasome, membrane protein
Biological sourceOvis aries (SHEEP)
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Cellular locationMitochondrion inner membrane ; Multi-pass membrane protein  P24959 O78749 O78750 O21619
Mitochondrion inner membrane  W5P2X9 W5P642 B9VH04 W5P2X9 W5PI52
Total number of polymer chains89
Total molecular weight1284762.74
Authors
Letts, J.A.,Fiedorczuk, F.,Sazanov, L.A. (deposition date: 2016-04-07, release date: 2016-09-21, Last modification date: 2017-08-02)
Primary citation
Letts, J.A.,Fiedorczuk, K.,Sazanov, L.A.
The architecture of respiratory supercomplexes.
Nature, 537:644-648, 2016
PubMed: 27654913 (PDB entries with the same primary citation)
DOI: 10.1038/nature19774
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliers342.0%6.2%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

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