Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5J7Y

Architecture of loose respirasome

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AA	0005739	cellular_component	mitochondrion
AA	0005743	cellular_component	mitochondrial inner membrane
AA	0005750	cellular_component	mitochondrial respiratory chain complex III
AA	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AA	0031625	molecular_function	ubiquitin protein ligase binding
AA	0046872	molecular_function	metal ion binding
AB	0004222	molecular_function	metalloendopeptidase activity
AB	0006508	biological_process	proteolysis
AB	0046872	molecular_function	metal ion binding
AC	0005739	cellular_component	mitochondrion
AC	0005743	cellular_component	mitochondrial inner membrane
AC	0005750	cellular_component	mitochondrial respiratory chain complex III
AC	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AC	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
AC	0009055	molecular_function	electron transfer activity
AC	0016020	cellular_component	membrane
AC	0016491	molecular_function	oxidoreductase activity
AC	0022904	biological_process	respiratory electron transport chain
AC	0045275	cellular_component	respiratory chain complex III
AC	0046872	molecular_function	metal ion binding
AC	0070469	cellular_component	respirasome
AC	1902600	biological_process	proton transmembrane transport
AD	0009055	molecular_function	electron transfer activity
AD	0020037	molecular_function	heme binding
AE	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
AE	0016020	cellular_component	membrane
AE	0051537	molecular_function	2 iron, 2 sulfur cluster binding
AF	0005739	cellular_component	mitochondrion
AF	0005743	cellular_component	mitochondrial inner membrane
AF	0005750	cellular_component	mitochondrial respiratory chain complex III
AF	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AF	0016020	cellular_component	membrane
AF	0070469	cellular_component	respirasome
AG	0005739	cellular_component	mitochondrion
AG	0005743	cellular_component	mitochondrial inner membrane
AG	0005750	cellular_component	mitochondrial respiratory chain complex III
AG	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AG	0016020	cellular_component	membrane
AG	0070469	cellular_component	respirasome
AH	0005750	cellular_component	mitochondrial respiratory chain complex III
AH	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AI	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
AJ	0005750	cellular_component	mitochondrial respiratory chain complex III
AJ	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AK	0005750	cellular_component	mitochondrial respiratory chain complex III
AK	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AL	0005739	cellular_component	mitochondrion
AL	0005743	cellular_component	mitochondrial inner membrane
AL	0005750	cellular_component	mitochondrial respiratory chain complex III
AL	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AL	0031625	molecular_function	ubiquitin protein ligase binding
AL	0046872	molecular_function	metal ion binding
AM	0004222	molecular_function	metalloendopeptidase activity
AM	0006508	biological_process	proteolysis
AM	0046872	molecular_function	metal ion binding
AN	0005739	cellular_component	mitochondrion
AN	0005743	cellular_component	mitochondrial inner membrane
AN	0005750	cellular_component	mitochondrial respiratory chain complex III
AN	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AN	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
AN	0009055	molecular_function	electron transfer activity
AN	0016020	cellular_component	membrane
AN	0016491	molecular_function	oxidoreductase activity
AN	0022904	biological_process	respiratory electron transport chain
AN	0045275	cellular_component	respiratory chain complex III
AN	0046872	molecular_function	metal ion binding
AN	0070469	cellular_component	respirasome
AN	1902600	biological_process	proton transmembrane transport
AO	0009055	molecular_function	electron transfer activity
AO	0020037	molecular_function	heme binding
AP	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
AP	0016020	cellular_component	membrane
AP	0051537	molecular_function	2 iron, 2 sulfur cluster binding
AQ	0005739	cellular_component	mitochondrion
AQ	0005743	cellular_component	mitochondrial inner membrane
AQ	0005750	cellular_component	mitochondrial respiratory chain complex III
AQ	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AQ	0016020	cellular_component	membrane
AQ	0070469	cellular_component	respirasome
AR	0005739	cellular_component	mitochondrion
AR	0005743	cellular_component	mitochondrial inner membrane
AR	0005750	cellular_component	mitochondrial respiratory chain complex III
AR	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AR	0016020	cellular_component	membrane
AR	0070469	cellular_component	respirasome
AS	0005750	cellular_component	mitochondrial respiratory chain complex III
AS	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AT	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
AU	0005750	cellular_component	mitochondrial respiratory chain complex III
AU	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AV	0005750	cellular_component	mitochondrial respiratory chain complex III
AV	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
BC	0004129	molecular_function	cytochrome-c oxidase activity
BC	0005739	cellular_component	mitochondrion
BC	0005743	cellular_component	mitochondrial inner membrane
BC	0005751	cellular_component	mitochondrial respiratory chain complex IV
BC	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
BC	0008535	biological_process	respiratory chain complex IV assembly
BC	0009055	molecular_function	electron transfer activity
BC	0016020	cellular_component	membrane
BC	0019646	biological_process	aerobic electron transport chain
BC	0022904	biological_process	respiratory electron transport chain
BC	0031966	cellular_component	mitochondrial membrane
BC	0045277	cellular_component	respiratory chain complex IV
BC	1902600	biological_process	proton transmembrane transport
BD	0005751	cellular_component	mitochondrial respiratory chain complex IV
BD	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
BE	0005743	cellular_component	mitochondrial inner membrane
BE	0005751	cellular_component	mitochondrial respiratory chain complex IV
BE	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
BG	0005743	cellular_component	mitochondrial inner membrane
BG	0005751	cellular_component	mitochondrial respiratory chain complex IV
BH	0005739	cellular_component	mitochondrion
BH	0045277	cellular_component	respiratory chain complex IV
BI	0005739	cellular_component	mitochondrion
BI	0005743	cellular_component	mitochondrial inner membrane
BI	0005751	cellular_component	mitochondrial respiratory chain complex IV
BI	0006119	biological_process	oxidative phosphorylation
BI	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
BI	0016020	cellular_component	membrane
BJ	0005746	cellular_component	mitochondrial respirasome
BJ	0005751	cellular_component	mitochondrial respiratory chain complex IV
BJ	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
BK	0005746	cellular_component	mitochondrial respirasome
BK	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
BL	0005751	cellular_component	mitochondrial respiratory chain complex IV
BL	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
BM	0005751	cellular_component	mitochondrial respiratory chain complex IV
BM	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
BN	0004129	molecular_function	cytochrome-c oxidase activity
BN	0005739	cellular_component	mitochondrion
BN	0005743	cellular_component	mitochondrial inner membrane
BN	0005750	cellular_component	mitochondrial respiratory chain complex III
BN	0005751	cellular_component	mitochondrial respiratory chain complex IV
BN	0006119	biological_process	oxidative phosphorylation
BN	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
BN	0009060	biological_process	aerobic respiration
BN	0015990	biological_process	electron transport coupled proton transport
BN	0016020	cellular_component	membrane
BN	0020037	molecular_function	heme binding
BN	0031966	cellular_component	mitochondrial membrane
BN	0045277	cellular_component	respiratory chain complex IV
BN	0046872	molecular_function	metal ion binding
BN	0070469	cellular_component	respirasome
BN	1902600	biological_process	proton transmembrane transport
BO	0004129	molecular_function	cytochrome-c oxidase activity
BO	0005507	molecular_function	copper ion binding
BO	0005739	cellular_component	mitochondrion
BO	0005743	cellular_component	mitochondrial inner membrane
BO	0005751	cellular_component	mitochondrial respiratory chain complex IV
BO	0016020	cellular_component	membrane
BO	0016491	molecular_function	oxidoreductase activity
BO	0022900	biological_process	electron transport chain
BO	0031966	cellular_component	mitochondrial membrane
BO	0042773	biological_process	ATP synthesis coupled electron transport
BO	0045277	cellular_component	respiratory chain complex IV
BO	0046872	molecular_function	metal ion binding
BO	0070469	cellular_component	respirasome
BO	1902600	biological_process	proton transmembrane transport
BP	0005740	cellular_component	mitochondrial envelope
BP	0005751	cellular_component	mitochondrial respiratory chain complex IV
BP	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
G	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00143
Number of Residues	24
Details	INSULINASE Insulinase family, zinc-binding region signature. GsryenfnnlGtSHLLRLAsSlTT

Chain	Residue	Details
AB	GLY54-THR77

site_id	PS00077
Number of Residues	56
Details	COX1_CUB Heme-copper oxidase catalytic subunit, copper B binding region signature. WFFGHPeVyililpgfgmishivtyysgkkepfgymgmvwammsigflgfivwa.HH

Chain	Residue	Details
BN	TRP236-HIS291

site_id	PS01329
Number of Residues	18
Details	COX6A Cytochrome c oxidase subunit VIa signature. IRtKpFsWGDGnHTfFhN

Chain	Residue	Details
BG	ILE55-ASN72

site_id	PS00848
Number of Residues	23
Details	COX5B_1 Cytochrome c oxidase subunit Vb, zinc binding region signature. VIWfwlhkgeaqrCpsCGthYKL

Chain	Residue	Details
BP	VAL69-LEU91

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	152
Details	TOPO_DOM: Mitochondrial intermembrane => ECO:0000269\|PubMed:27654913

Chain	Residue	Details
BO	MET1-SER14
AN	TRP77-VAL98
AN	TRP113-LEU133
AN	PHE178-LEU198
AN	ILE226-THR246
AN	LEU288-HIS308
AN	ILE320-GLY340
AN	TYR347-PRO367
BO	ASP88-LEU227
BN	MET171-PRO182
BN	SER262-GLY269
BN	HIS328-SER335
BN	SER401-ASN406
BN	LYS479-LYS514
AC	TYR347-PRO367
AN	PHE33-MET53

site_id	SWS_FT_FI2
Number of Residues	30
Details	TRANSMEM: Helical; Name=I => ECO:0000250\|UniProtKB:P68530

Chain	Residue	Details
BO	PRO15-MET45
AC	HIS97
AC	HIS182
AC	HIS196
AN	HIS83
AN	HIS97
AN	HIS182
AN	HIS196

site_id	SWS_FT_FI3
Number of Residues	13
Details	TOPO_DOM: Mitochondrial matrix => ECO:0000269\|PubMed:27654913

Chain	Residue	Details
BO	LEU46-GLN59
BN	VAL118-GLY140
BN	ARG213-ASP227
BN	VAL287-ASP298
BN	LEU358-THR370
BN	SER434-ALA446

site_id	SWS_FT_FI4
Number of Residues	27
Details	TRANSMEM: Helical; Name=II => ECO:0000250\|UniProtKB:P68530

Chain	Residue	Details
BO	GLU60-MET87
BC	GLU152-ASN154
BC	LYS223-HIS231

site_id	SWS_FT_FI5
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269\|PubMed:27654913

Chain	Residue	Details
BO	CYS196
BO	CYS200
BO	HIS204
BO	MET207

site_id	SWS_FT_FI6
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P68530

Chain	Residue	Details
BO	GLU198

site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: Phosphotyrosine => ECO:0000250\|UniProtKB:P00406

Chain	Residue	Details
BO	TYR218

site_id	SWS_FT_FI8
Number of Residues	33
Details	TRANSMEM: Helical; Name=VI => ECO:0000250\|UniProtKB:P00396

Chain	Residue	Details
BN	PRO228-TYR261

site_id	SWS_FT_FI9
Number of Residues	16
Details	TRANSMEM: Helical; Name=VII => ECO:0000250\|UniProtKB:P00396

Chain	Residue	Details
BN	TYR270-ILE286

site_id	SWS_FT_FI10
Number of Residues	28
Details	TRANSMEM: Helical; Name=VIII => ECO:0000250\|UniProtKB:P00396

Chain	Residue	Details
BN	VAL299-LEU327

site_id	SWS_FT_FI11
Number of Residues	21
Details	TRANSMEM: Helical; Name=IX => ECO:0000250\|UniProtKB:P00396

Chain	Residue	Details
BN	PRO336-VAL357

site_id	SWS_FT_FI12
Number of Residues	29
Details	TRANSMEM: Helical; Name=X => ECO:0000250\|UniProtKB:P00396

Chain	Residue	Details
BN	TYR371-PHE400

site_id	SWS_FT_FI13
Number of Residues	26
Details	TRANSMEM: Helical; Name=XI => ECO:0000250\|UniProtKB:P00396

Chain	Residue	Details
BN	ASP407-LEU433

site_id	SWS_FT_FI14
Number of Residues	31
Details	TRANSMEM: Helical; Name=XII => ECO:0000250\|UniProtKB:P00396

Chain	Residue	Details
BN	TYR447-SER478

site_id	SWS_FT_FI15
Number of Residues	6
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P00396

Chain	Residue	Details
BN	GLU40
BN	GLY45
BN	TYR244
BN	HIS368
BN	ASP369
BN	SER441

site_id	SWS_FT_FI16
Number of Residues	3
Details	BINDING: axial binding residue => ECO:0000269\|PubMed:27654913

Chain	Residue	Details
BN	HIS61
BN	HIS376
BN	HIS378

site_id	SWS_FT_FI17
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269\|PubMed:27654913

Chain	Residue	Details
BN	HIS240
BN	HIS290
BN	HIS291

site_id	SWS_FT_FI18
Number of Residues	2
Details	CROSSLNK: 1'-histidyl-3'-tyrosine (His-Tyr) => ECO:0000250\|UniProtKB:P00396

Chain	Residue	Details
BN	HIS240
BN	TYR244

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)