2B7L
 
 | | Crystal Structure of CTP:Glycerol-3-Phosphate Cytidylyltransferase from Staphylococcus aureus | | Descriptor: | glycerol-3-phosphate cytidylyltransferase | | Authors: | Fong, D.H, Yim, V.C.-N, D'Elia, M.A, Brown, E.D, Berghuis, A.M. | | Deposit date: | 2005-10-04 | | Release date: | 2006-06-27 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of CTP:glycerol-3-phosphate cytidylyltransferase from Staphylococcus aureus: examination of structural basis for kinetic mechanism.
Biochim.Biophys.Acta, 1764, 2006
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2B9R
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8T0N
 | | Structure of Compound 4 bound to human ALDH1A1 | | Descriptor: | 2-methoxy-6-{[(1-propyl-1H-benzimidazol-2-yl)amino]methyl}phenol, Aldehyde dehydrogenase 1A1, CHLORIDE ION, ... | | Authors: | Hurley, T.D. | | Deposit date: | 2023-06-01 | | Release date: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Development of substituted benzimidazoles as inhibitors of human aldehyde dehydrogenase 1A isoenzymes.
Chem.Biol.Interact., 391, 2024
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2B0M
 | | Human dihydroorotate dehydrogenase bound to a novel inhibitor | | Descriptor: | 3-AMIDO-5-BIPHENYL-BENZOIC ACID, Dihydroorotate dehydrogenase, mitochondrial, ... | | Authors: | Hurt, D.E, Sutton, A.E, Clardy, J. | | Deposit date: | 2005-09-14 | | Release date: | 2005-09-27 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Brequinar derivatives and species-specific drug design for dihydroorotate dehydrogenase.
Bioorg.Med.Chem.Lett., 16, 2006
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2AH4
 | | guanidinobenzoyl-trypsin acyl-enzyme at 1.13 A resolution | | Descriptor: | 4-carbamimidamidobenzoic acid, CALCIUM ION, SULFATE ION, ... | | Authors: | Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E. | | Deposit date: | 2005-07-26 | | Release date: | 2006-05-16 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.13 Å) | | Cite: | Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
Proc.Natl.Acad.Sci.USA, 103, 2006
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2AKC
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2B30
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2B44
 | | Truncated S. aureus LytM, P 32 2 1 crystal form | | Descriptor: | Glycyl-glycine endopeptidase lytM, PHOSPHATE ION, ZINC ION | | Authors: | Firczuk, M, Mucha, A, Bochtler, M. | | Deposit date: | 2005-09-22 | | Release date: | 2006-01-10 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Crystal structures of active LytM.
J.Mol.Biol., 354, 2005
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8SP7
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8SP5
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2ANY
 | | Expression, Crystallization and the Three-dimensional Structure of the Catalytic Domain of Human Plasma Kallikrein: Implications for Structure-Based Design of Protease Inhibitors | | Descriptor: | BENZAMIDINE, PHOSPHATE ION, plasma kallikrein, ... | | Authors: | Tang, J, Yu, C.L, Williams, S.R, Springman, E, Jeffery, D, Sprengeler, P.A, Estevez, A, Sampang, J, Shrader, W, Spencer, J.R, Young, W.B, McGrath, M.E, Katz, B.A. | | Deposit date: | 2005-08-11 | | Release date: | 2005-10-11 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Expression, crystallization, and three-dimensional structure of the catalytic domain of human plasma kallikrein.
J.Biol.Chem., 280, 2005
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5A0C
 | | Crystal Structure of human neutrophil elastase in complex with a dihydropyrimidone inhibitor | | Descriptor: | (6S)-6-(4-cyano-2-methylsulfonyl-phenyl)-4-methyl-2-oxidanylidene-3-[3-(trifluoromethyl)phenyl]-1,6-dihydropyrimidine-5-carbonitrile, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | vonNussbaum, F, Li, V.M.-J, Allerheiligen, S, Anlauf, S, Baerfacker, L, Bechem, M, Delbeck, M, Fitzgerald, M.F, Gerisch, M, Gielen-Haertwig, H, Haning, H, Karthaus, D, Lang, D, Lustig, K, Meibom, D, Mittendorf, J, Rosentreter, U, Schaefer, M, Schaefer, S, Schamberger, J, Telan, L.A, Tersteegen, A. | | Deposit date: | 2015-04-17 | | Release date: | 2015-08-19 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases.
ChemMedChem, 10, 2015
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2B6O
 | | Electron crystallographic structure of lens Aquaporin-0 (AQP0) (lens MIP) at 1.9A resolution, in a closed pore state | | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Lens fiber major intrinsic protein | | Authors: | Gonen, T, Cheng, Y, Sliz, P, Hiroaki, Y, Fujiyoshi, Y, Harrison, S.C, Walz, T. | | Deposit date: | 2005-10-03 | | Release date: | 2005-12-06 | | Last modified: | 2023-08-23 | | Method: | ELECTRON CRYSTALLOGRAPHY (1.9 Å) | | Cite: | Lipid-protein interactions in double-layered two-dimensional AQP0 crystals.
Nature, 438, 2005
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2ARI
 | | Solution structure of micelle-bound fusion domain of HIV-1 gp41 | | Descriptor: | Envelope polyprotein GP160 | | Authors: | Jaroniec, C.P, Kaufman, J.D, Stahl, S.J, Viard, M, Blumenthal, R, Wingfield, P.T, Bax, A. | | Deposit date: | 2005-08-19 | | Release date: | 2005-12-20 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure and Dynamics of Micelle-Associated Human Immunodeficiency Virus gp41 Fusion Domain.
Biochemistry, 44, 2005
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4UDP
 | | Crystal structure of 5-hydroxymethylfurfural oxidase (HMFO) in the oxidized state | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE | | Authors: | Dijkman, W, Binda, C, Fraaije, M, Mattevi, A. | | Deposit date: | 2014-12-11 | | Release date: | 2015-03-18 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure-Based Enzyme Tailoring of 5-Hydroxymethylfurfural Oxidase
Acs Catalysis, 5, 2015
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8SZ5
 | | [2T5] Self-assembling DNA motif with 5 base pairs between junctions and P32 symmetry | | Descriptor: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*AP*CP*CP*TP*G)-3'), DNA (5'-D(P*AP*CP*GP*AP*CP*AP*CP*TP*CP*A)-3'), DNA (5'-D(P*CP*AP*CP*GP*T)-3'), ... | | Authors: | Vecchioni, S, Janowski, J, Sha, R, Ohayon, Y.P. | | Deposit date: | 2023-05-26 | | Release date: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | Engineering tertiary chirality in helical biopolymers.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8SWB
 | | RNase H complex with streopure ASO and RNA | | Descriptor: | DI(HYDROXYETHYL)ETHER, DNA (5'-R(*(OMC)P*(N7X)P*(T39)P*(C5L)P*(A2M))-D(P*(SC)P*(PST)P*(SC)P*AP*(SC)P*(SC)P*(RC)P*(AS)P*(SC)P*(PST))-R(P*(6OO)P*(RFJ)P*(6OO)P*(6OO)P*(6NW))-3'), GLYCEROL, ... | | Authors: | Cho, Y.-J, Iwamoto, N. | | Deposit date: | 2023-05-18 | | Release date: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of RNase H/RNA/PS-ASO complex at an atomic level
To Be Published
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4UDU
 | | Crystal structure of staphylococcal enterotoxin E in complex with a T cell receptor | | Descriptor: | ENTEROTOXIN TYPE E, PROTEIN TRBV7-9, T-CELL RECEPTOR BETA-2 CHAIN C REGION, ... | | Authors: | Rodstrom, K.E.J, Regenthal, P, Lindkvist-Petersson, K. | | Deposit date: | 2014-12-11 | | Release date: | 2015-06-24 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of Staphylococcal Enterotoxin E in Complex with Tcr Defines the Role of Tcr Loop Positioning in Superantigen Recognition.
Plos One, 10, 2015
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8SSL
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2B2I
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2AVD
 | | Crystal Structure of Human Catechol-O-methyltransferase domain containing 1 | | Descriptor: | Catechol-O-methyltransferase, S-ADENOSYLMETHIONINE | | Authors: | Min, J.R, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | | Deposit date: | 2005-08-29 | | Release date: | 2005-09-13 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Crystal Structure of Human Catechol-O-methyltransferase
domain containing 1 in complex with S-adenosyl-L-methionine
To be Published
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5A8N
 | | Crystal structure of the native form of beta-glucanase SdGluc5_26A from Saccharophagus degradans | | Descriptor: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Sulzenbacher, G, Lafond, M, Freyd, T, Henrissat, B, Coutinho, R.M, Berrin, J.G, Garron, M.L. | | Deposit date: | 2015-07-16 | | Release date: | 2016-01-20 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | The Quaternary Structure of a Glycoside Hydrolase Dictates Specificity Towards Beta-Glucans
J.Biol.Chem., 291, 2016
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2B8Q
 | | X-ray structure of Acanthamoeba ployphaga mimivirus nucleoside diphosphate kinase complexed with TDP | | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, Probable nucleoside diphosphate kinase, ... | | Authors: | Jeudy, S, Claverie, J.M, Abergel, C. | | Deposit date: | 2005-10-10 | | Release date: | 2005-11-15 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Dissecting the unique nucleotide specificity of mimivirus nucleoside diphosphate kinase.
J.Virol., 83, 2009
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2B97
 | | Ultra-high resolution structure of hydrophobin HFBII | | Descriptor: | Hydrophobin II, MANGANESE (II) ION | | Authors: | Hakanpaa, J, Linder, M, Popov, A, Schmidt, A, Rouvinen, J. | | Deposit date: | 2005-10-11 | | Release date: | 2006-03-28 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (0.75 Å) | | Cite: | Hydrophobin HFBII in detail: ultrahigh-resolution structure at 0.75 A.
Acta Crystallogr.,Sect.D, 62, 2006
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2B1X
 | | Crystal structure of naphthalene 1,2-dioxygenase from Rhodococcus sp. | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, ... | | Authors: | Gakhar, L, Malik, Z.A, Allen, C.C, Lipscomb, D.A, Larkin, M.J, Ramaswamy, S. | | Deposit date: | 2005-09-16 | | Release date: | 2005-10-04 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure and Increased Thermostability of Rhodococcus sp. Naphthalene 1,2-Dioxygenase.
J.Bacteriol., 187, 2005
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