1A7C
| HUMAN PLASMINOGEN ACTIVATOR INHIBITOR TYPE-1 IN COMPLEX WITH A PENTAPEPTIDE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-D-ribopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PENTAPEPTIDE, ... | Authors: | Xue, Y, Inghardt, T, Sjolin, L, Deinum, J. | Deposit date: | 1998-03-12 | Release date: | 1999-03-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Interfering with the inhibitory mechanism of serpins: crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop peptide Structure, 6, 1998
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3K5D
| Crystal Structure of BACE-1 in complex with AHM178 | Descriptor: | Beta-secretase 1, N-acetyl-L-leucyl-N-[(4S,5S,7R)-8-(butylamino)-5-hydroxy-2,7-dimethyl-8-oxooctan-4-yl]-L-methioninamide | Authors: | Rondeau, J.-M. | Deposit date: | 2009-10-07 | Release date: | 2010-05-05 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure-based design and synthesis of novel P2/P3 modified, non-peptidic beta-secretase (BACE-1) inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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2LL4
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2LCF
| Solution structure of GppNHp-bound H-RasT35S mutant protein | Descriptor: | GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Araki, M, Shima, F, Yoshikawa, Y, Muraoka, S, Ijiri, Y, Nagahara, Y, Shirono, T, Kataoka, T, Tamura, A. | Deposit date: | 2011-04-28 | Release date: | 2011-09-28 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the state 1 conformer of GTP-bound H-Ras protein and distinct dynamic properties between the state 1 and state 2 conformers. J.Biol.Chem., 286, 2011
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2LMU
| Androcam at high calcium | Descriptor: | CALCIUM ION, Calmodulin-related protein 97A | Authors: | Joshi, M.K, Moran, S.T, Beckingham, K.M, Mackenzie, K.R. | Deposit date: | 2011-12-12 | Release date: | 2012-08-22 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of androcam supports specialized interactions with myosin VI. Proc.Natl.Acad.Sci.USA, 109, 2012
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3K6F
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3JYA
| Discovery of 3H-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective and Orally Bioavailable Pim Kinases Inhibitors | Descriptor: | 6,9-dichloro[1]benzothieno[3,2-d]pyrimidin-4(3H)-one, Proto-oncogene serine/threonine-protein kinase Pim-1 | Authors: | Stoll, V.S. | Deposit date: | 2009-09-21 | Release date: | 2009-11-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Discovery of 3H-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective and Orally Bioavailable Pim Kinases Inhibitors TO BE PUBLISHED
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1AFB
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1AMH
| UNCOMPLEXED RAT TRYPSIN MUTANT WITH ASP 189 REPLACED WITH SER (D189S) | Descriptor: | ANIONIC TRYPSIN, CALCIUM ION | Authors: | Szabo, E, Bocskei, Z.S, Naray-Szabo, G, Graf, L. | Deposit date: | 1997-06-17 | Release date: | 1997-12-24 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The three-dimensional structure of Asp189Ser trypsin provides evidence for an inherent structural plasticity of the protease. Eur.J.Biochem., 263, 1999
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3K9V
| Crystal structure of rat mitochondrial P450 24A1 S57D in complex with CHAPS | Descriptor: | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ... | Authors: | Annalora, A.J, Goodin, D.B, Hong, W, Zhang, Q, Johnson, E.F, Stout, C.D. | Deposit date: | 2009-10-16 | Release date: | 2009-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism. J.Mol.Biol., 396, 2010
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7C3G
| Crystal structure of human ALK2 kinase domain with R206H mutation in complex with a bicyclic pyrazole inhibitor RK-73134 | Descriptor: | 1,2-ETHANEDIOL, Activin receptor type-1, SULFATE ION, ... | Authors: | Sakai, N, Mishima-Tsumagari, C, Matsumoto, T, Shirouzu, M. | Deposit date: | 2020-05-12 | Release date: | 2021-03-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.802 Å) | Cite: | Novel bicyclic pyrazoles as potent ALK2 (R206H) inhibitors for the treatment of fibrodysplasia ossificans progressiva. Bioorg.Med.Chem.Lett., 38, 2021
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3K3U
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1AAL
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3K5G
| Human bace-1 complex with bjc060 | Descriptor: | (1R,3S)-N-[(1S,2R)-1-benzyl-2-hydroxy-3-{[3-(1-methylethyl)benzyl]amino}propyl]-3-[1-methyl-1-(2-oxopiperidin-1-yl)ethyl]cyclohexanecarboxamide, Beta-secretase 1 | Authors: | Rondeau, J.-M. | Deposit date: | 2009-10-07 | Release date: | 2010-05-05 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-based design and synthesis of novel P2/P3 modified, non-peptidic beta-secretase (BACE-1) inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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2LKC
| Free B.st IF2-G2 | Descriptor: | Translation initiation factor IF-2 | Authors: | Wienk, H, Tishchenko, E, Belardinelli, R, Tomaselli, S, Dongre, R, Spurio, R, Folkers, G.E, Gualerzi, C.O, Boelens, R. | Deposit date: | 2011-10-10 | Release date: | 2012-02-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Dynamics of Bacterial Translation Initiation Factor IF2. J.Biol.Chem., 287, 2012
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7CDM
| Lysozyme room-temperature structure determined by SS-ROX combined with HAG method, 42 kGy (4500 images from 2nd half of data set) | Descriptor: | Lysozyme C, MALONATE ION, SODIUM ION | Authors: | Hasegawa, K, Baba, S, Kawamura, T, Yamamoto, M, Kumasaka, T. | Deposit date: | 2020-06-20 | Release date: | 2021-03-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Evaluation of the data-collection strategy for room-temperature micro-crystallography studied by serial synchrotron rotation crystallography combined with the humid air and glue-coating method. Acta Crystallogr.,Sect.D, 77, 2021
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7CDN
| Lysozyme room-temperature structure determined by SS-ROX combined with HAG method, 42 kGy (9000 images) | Descriptor: | Lysozyme C, MALONATE ION, SODIUM ION | Authors: | Hasegawa, K, Baba, S, Kawamura, T, Yamamoto, M, Kumasaka, T. | Deposit date: | 2020-06-20 | Release date: | 2021-03-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Evaluation of the data-collection strategy for room-temperature micro-crystallography studied by serial synchrotron rotation crystallography combined with the humid air and glue-coating method. Acta Crystallogr.,Sect.D, 77, 2021
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3J8J
| Tilted state of actin, T1 | Descriptor: | Actin, alpha skeletal muscle | Authors: | Galkin, V.E, Orlova, A, Vos, M.R, Schroder, G.F, Egelman, E.H. | Deposit date: | 2014-11-07 | Release date: | 2015-01-14 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (12 Å) | Cite: | Near-atomic resolution for one state of f-actin. Structure, 23, 2015
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7CDP
| Lysozyme room-temperature structure determined by SS-ROX combined with HAG method, 42 kGy (3000 images) | Descriptor: | Lysozyme C, MALONATE ION, SODIUM ION | Authors: | Hasegawa, K, Baba, S, Kawamura, T, Yamamoto, M, Kumasaka, T. | Deposit date: | 2020-06-20 | Release date: | 2021-03-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Evaluation of the data-collection strategy for room-temperature micro-crystallography studied by serial synchrotron rotation crystallography combined with the humid air and glue-coating method. Acta Crystallogr.,Sect.D, 77, 2021
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1AE5
| HUMAN HEPARIN BINDING PROTEIN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HEPARIN BINDING PROTEIN | Authors: | Iversen, L.F, Kastrup, J.S, Bjorn, S.E, Rasmussen, P.B, Wiberg, F.C, Flodgaard, H.J, Larsen, I.K. | Deposit date: | 1997-03-05 | Release date: | 1998-03-11 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of HBP, a multifunctional protein with a serine proteinase fold. Nat.Struct.Biol., 4, 1997
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7CDQ
| Lysozyme room-temperature structure determined by SS-ROX combined with HAG method, 83 kGy (3000 images) | Descriptor: | Lysozyme C, MALONATE ION, SODIUM ION | Authors: | Hasegawa, K, Baba, S, Kawamura, T, Yamamoto, M, Kumasaka, T. | Deposit date: | 2020-06-20 | Release date: | 2021-03-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Evaluation of the data-collection strategy for room-temperature micro-crystallography studied by serial synchrotron rotation crystallography combined with the humid air and glue-coating method. Acta Crystallogr.,Sect.D, 77, 2021
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1A0L
| HUMAN BETA-TRYPTASE: A RING-LIKE TETRAMER WITH ACTIVE SITES FACING A CENTRAL PORE | Descriptor: | (2S)-3-(4-carbamimidoylphenyl)-2-hydroxypropanoic acid, BETA-TRYPTASE | Authors: | Pereira, P.J.B, Bergner, A, Macedo-Ribeiro, S, Huber, R, Matschiner, G, Fritz, H, Sommerhoff, C.P, Bode, W. | Deposit date: | 1997-12-03 | Release date: | 1999-03-23 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Human beta-tryptase is a ring-like tetramer with active sites facing a central pore. Nature, 392, 1998
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7CDR
| Lysozyme room-temperature structure determined by SS-ROX combined with HAG method, 210 kGy (3000 images) | Descriptor: | Lysozyme C, MALONATE ION, SODIUM ION | Authors: | Hasegawa, K, Baba, S, Kawamura, T, Yamamoto, M, Kumasaka, T. | Deposit date: | 2020-06-20 | Release date: | 2021-03-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Evaluation of the data-collection strategy for room-temperature micro-crystallography studied by serial synchrotron rotation crystallography combined with the humid air and glue-coating method. Acta Crystallogr.,Sect.D, 77, 2021
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1A1G
| DSNR (ZIF268 VARIANT) ZINC FINGER-DNA COMPLEX (GCGT SITE) | Descriptor: | DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*CP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*GP*CP*CP*CP*AP*CP*GP*C)-3'), DSNR ZINC FINGER PEPTIDE, ... | Authors: | Elrod-Erickson, M, Benson, T.E, Pabo, C.O. | Deposit date: | 1997-12-10 | Release date: | 1998-06-10 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | High-resolution structures of variant Zif268-DNA complexes: implications for understanding zinc finger-DNA recognition. Structure, 6, 1998
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1AFU
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