7JRH
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6LKG
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![BU of 6lkg by Molmil](/molmil-images/mine/6lkg) | two-component system protein mediate signal transduction | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, ABC transporter, solute-binding protein, ... | Authors: | Wang, M, Tao, Y. | Deposit date: | 2019-12-19 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.948 Å) | Cite: | Interface switch mediates signal transmission in a two-component system. Proc.Natl.Acad.Sci.USA, 117, 2020
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6LKJ
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![BU of 6lkj by Molmil](/molmil-images/mine/6lkj) | Two-component system protein mediate signal transduction | Descriptor: | 6-O-phosphono-beta-D-galactopyranose, ABC transporter, solute-binding protein | Authors: | Wang, M, Tao, Y. | Deposit date: | 2019-12-19 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.004 Å) | Cite: | Interface switch mediates signal transmission in a two-component system. Proc.Natl.Acad.Sci.USA, 117, 2020
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5J89
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![BU of 5j89 by Molmil](/molmil-images/mine/5j89) | Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor | Descriptor: | 1,2-ETHANEDIOL, N-{2-[({2-methoxy-6-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]pyridin-3-yl}methyl)amino]ethyl}acetamide, Programmed cell death 1 ligand 1 | Authors: | Zak, K.M, Grudnik, P, Guzik, K, Zieba, B.J, Musielak, B, Doemling, P, Dubin, G, Holak, T.A. | Deposit date: | 2016-04-07 | Release date: | 2016-04-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1). Oncotarget, 7, 2016
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1XO0
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![BU of 1xo0 by Molmil](/molmil-images/mine/1xo0) | High resolution structure of the holliday junction intermediate in cre-loxp site-specific recombination | Descriptor: | Recombinase CRE, loxP | Authors: | Ghosh, K, Lau, C.K, Guo, F, Segall, A.M, Van Duyne, G.D. | Deposit date: | 2004-10-05 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Peptide trapping of the Holliday junction intermediate in Cre-loxP site-specific recombination. J.Biol.Chem., 280, 2005
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5J8O
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![BU of 5j8o by Molmil](/molmil-images/mine/5j8o) | Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor | Descriptor: | (2R)-1-({3-bromo-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl}methyl)piperidine-2-carboxylic acid, Programmed cell death 1 ligand 1 | Authors: | Zak, K.M, Grudnik, P, Guzik, K, Zieba, B.J, Musielak, B, Doemling, P, Dubin, G, Holak, T.A. | Deposit date: | 2016-04-08 | Release date: | 2016-04-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1). Oncotarget, 7, 2016
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3P9Y
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6NIW
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![BU of 6niw by Molmil](/molmil-images/mine/6niw) | Crystal structure of P[6] rotavirus | Descriptor: | DI(HYDROXYETHYL)ETHER, Protease-sensitive outer capsid protein | Authors: | Xu, S, Liu, Y, Lakamp, L, Ahmed, L, Jiang, X, Kennedy, M.A. | Deposit date: | 2019-01-01 | Release date: | 2020-01-08 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Molecular basis of P[II] major human rotavirus VP8* domain recognition of histo-blood group antigens. Plos Pathog., 16, 2020
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6LKK
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![BU of 6lkk by Molmil](/molmil-images/mine/6lkk) | Two-component system protein mediate signal transduction | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, ABC transporter, solute-binding protein | Authors: | Wang, M, Tao, Y. | Deposit date: | 2019-12-19 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.502 Å) | Cite: | Interface switch mediates signal transmission in a two-component system. Proc.Natl.Acad.Sci.USA, 117, 2020
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6LKL
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![BU of 6lkl by Molmil](/molmil-images/mine/6lkl) | Two-component system protein mediate signal transduction | Descriptor: | ABC transporter, solute-binding protein, MALONIC ACID | Authors: | Wang, M, Tao, Y. | Deposit date: | 2019-12-19 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.213 Å) | Cite: | Interface switch mediates signal transmission in a two-component system. Proc.Natl.Acad.Sci.USA, 117, 2020
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1ZV5
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![BU of 1zv5 by Molmil](/molmil-images/mine/1zv5) | Crystal structure of the variable domain of the camelid heavy-chain antibody D2-L29 in complex with hen egg white lysozyme | Descriptor: | Lysozyme C, PHOSPHATE ION, immunoglobulin heavy chain antibody variable domain | Authors: | De Genst, E, Silence, K, Decanniere, K, Conrath, K, Loris, R, Kinne, J, Muyldermans, S, Wyns, L. | Deposit date: | 2005-06-01 | Release date: | 2006-04-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies. Proc.Natl.Acad.Sci.Usa, 103, 2006
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6LKI
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![BU of 6lki by Molmil](/molmil-images/mine/6lki) | Two-component system protein mediate signal transduction | Descriptor: | ABC transporter, solute-binding protein, MALONIC ACID, ... | Authors: | Wang, M, Tao, Y. | Deposit date: | 2019-12-19 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.781 Å) | Cite: | Interface switch mediates signal transmission in a two-component system. Proc.Natl.Acad.Sci.USA, 117, 2020
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1NVM
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![BU of 1nvm by Molmil](/molmil-images/mine/1nvm) | Crystal structure of a bifunctional aldolase-dehydrogenase : sequestering a reactive and volatile intermediate | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 4-hydroxy-2-oxovalerate aldolase, MANGANESE (II) ION, ... | Authors: | Manjasetty, A.B, Powlowski, J, Vrielink, A. | Deposit date: | 2003-02-04 | Release date: | 2003-06-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of a bifunctional aldolase-dehydrogenase: Sequestering a
reactive and volatile intermediate Proc.Natl.Acad.Sci.USA, 100, 2003
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7MLX
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1P03
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3CRX
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4B3Z
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![BU of 4b3z by Molmil](/molmil-images/mine/4b3z) | Structure of the human collapsin response mediator protein-1, a lung cancer suppressor | Descriptor: | DIHYDROPYRIMIDINASE-RELATED PROTEIN 1 | Authors: | Liu, S.H, Lin, Y.H, Huang, S.F, Niou, Y.K, Huang, L.L, Chen, Y.J. | Deposit date: | 2012-07-27 | Release date: | 2013-08-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structure of Human Collapsin Response Mediator Protein 1: A Possible Role of its C-Terminal Tail. Acta Crystallogr.,Sect.F, 71, 2015
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2RDM
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![BU of 2rdm by Molmil](/molmil-images/mine/2rdm) | Crystal structure of response regulator receiver protein from Sinorhizobium medicae WSM419 | Descriptor: | GLYCEROL, Response regulator receiver protein | Authors: | Patskovsky, Y, Yan, Q, Zhan, C, Toro, R, Meyer, A.J, Gilmore, M, Hu, S, Groshong, C, Rodgers, L, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-09-24 | Release date: | 2007-10-09 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal structure of response regulator receiver protein from Sinorhizobium medicae WSM419. To be Published
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3VSJ
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![BU of 3vsj by Molmil](/molmil-images/mine/3vsj) | Crystal structure of 1,6-APD (2-ANIMOPHENOL-1,6-DIOXYGENASE) complexed with intermediate products | Descriptor: | (2Z,4Z)-2-imino-6-oxohex-4-enoic acid, (3E)-3-iminooxepin-2(3H)-one, 2-amino-5-chlorophenol 1,6-dioxygenase alpha subunit, ... | Authors: | Li, D.F, Hou, Y.J, Hu, Y, Wang, D.C, Liu, W. | Deposit date: | 2012-04-25 | Release date: | 2013-01-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of aminophenol dioxygenase in complex with intermediate, product and inhibitor Acta Crystallogr.,Sect.D, 69, 2013
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2DEU
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![BU of 2deu by Molmil](/molmil-images/mine/2deu) | Cocrystal structure of an RNA sulfuration enzyme MnmA and tRNA-Glu in the adenylated intermediate state | Descriptor: | ADENOSINE MONOPHOSPHATE, SULFATE ION, tRNA, ... | Authors: | Numata, T, Ikeuchi, Y, Fukai, S, Suzuki, T, Nureki, O. | Deposit date: | 2006-02-17 | Release date: | 2006-08-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Snapshots of tRNA sulphuration via an adenylated intermediate Nature, 442, 2006
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2RSU
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![BU of 2rsu by Molmil](/molmil-images/mine/2rsu) | Alternative structure of Ubiquitin | Descriptor: | Ubiquitin | Authors: | Kitazawa, S, Kameda, T, Yagi-Utsumi, M, Kato, K, Kitahara, R. | Deposit date: | 2012-06-15 | Release date: | 2013-03-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Q41N Variant of Ubiquitin as a Model for the Alternatively Folded N2 State of Ubiquitin Biochemistry, 52, 2013
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2MY3
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5YRS
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![BU of 5yrs by Molmil](/molmil-images/mine/5yrs) | X-ray Snapshot of HIV-1 Protease in Action: Observation of Tetrahedral Intermediate and Its SIHB with Catalytic Aspartate | Descriptor: | PROTEASE, RT-RH oligopeprtide | Authors: | Das, A, Mahale, S, Prashar, V, Bihani, S, Ferrer, J.-L, Hosur, M.V. | Deposit date: | 2017-11-10 | Release date: | 2018-03-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | X-ray snapshot of HIV-1 protease in action: observation of tetrahedral intermediate and short ionic hydrogen bond SIHB with catalytic aspartate. J. Am. Chem. Soc., 132, 2010
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4WL9
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1Q36
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![BU of 1q36 by Molmil](/molmil-images/mine/1q36) | EPSP synthase (Asp313Ala) liganded with tetrahedral reaction intermediate | Descriptor: | 3-phosphoshikimate 1-carboxyvinyltransferase, 5-(1-CARBOXY-1-PHOSPHONOOXY-ETHOXYL)-4-HYDROXY-3-PHOSPHONOOXY-CYCLOHEX-1-ENECARBOXYLIC ACID, FORMIC ACID | Authors: | Eschenburg, S, Kabsch, W, Healy, M.L, Schonbrunn, E. | Deposit date: | 2003-07-28 | Release date: | 2003-12-16 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A New View of the Mechanisms of UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) and 5-Enolpyruvylshikimate-3-phosphate Synthase (AroA) Derived from X-ray Structures of Their Tetrahedral Reaction Intermediate States. J.Biol.Chem., 278, 2003
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