3H6D
| Structure of the mycobacterium tuberculosis DUTPase D28N mutant | Descriptor: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | Authors: | Leveles, I, Harmat, V, Nagy, G, Takacs, E, Lopata, A, Toth, J, Vertessy, B.G. | Deposit date: | 2009-04-23 | Release date: | 2009-11-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases. Febs Lett., 584, 2010
|
|
3MBQ
| |
3P48
| Structure of the yeast dUTPase DUT1 in complex with dUMPNPP | Descriptor: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION | Authors: | Petit, P, Singer, A.U, Evdokimova, E, Kudritska, M, Edwards, A.M, Yakunin, A.F, Savchenko, A, Ontario Centre for Structural Proteomics (OCSP) | Deposit date: | 2010-10-06 | Release date: | 2010-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Structure and activity of the Saccharomyces cerevisiae dUTP pyrophosphatase DUT1, an essential housekeeping enzyme. Biochem.J., 437, 2011
|
|
2D4N
| Crystal Structure of M-PMV dUTPase complexed with dUPNPP, substrate analogue | Descriptor: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DU, ... | Authors: | Nemeth, V, Barabas, O, Vertessy, G.B. | Deposit date: | 2005-10-20 | Release date: | 2006-11-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Flexible segments modulate co-folding of dUTPase and nucleocapsid proteins. Nucleic Acids Res., 35, 2007
|
|
2BSY
| Epstein Barr Virus dUTPase | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE, SULFATE ION | Authors: | Tarbouriech, N, Buisson, M, Seigneurin, J.-M, Cusack, S, Burmeister, W.P. | Deposit date: | 2005-05-24 | Release date: | 2005-09-15 | Last modified: | 2023-03-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The Monomeric Dutpase from Epstein-Barr Virus Mimics Trimeric Dutpases Structure, 13, 2005
|
|
2BT1
| Epstein Barr Virus dUTPase in complex with a,b-imino dUTP | Descriptor: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE, MAGNESIUM ION | Authors: | Tarbouriech, N, Buisson, M, Seigneurin, J.-M, Cusack, S, Burmeister, W.P. | Deposit date: | 2005-05-24 | Release date: | 2005-09-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Monomeric Dutpase from Epstein-Barr Virus Mimics Trimeric Dutpases Structure, 13, 2005
|
|
2BAZ
| |
2D4M
| |
2D4L
| |
6LJJ
| Swine dUTPase in complex with alpha,beta-iminodUTP and magnesium ion | Descriptor: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform 1, ... | Authors: | Liang, R, Peng, G.Q. | Deposit date: | 2019-12-16 | Release date: | 2020-11-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Structural comparisons of host and African swine fever virus dUTPases reveal new clues for inhibitor development. J.Biol.Chem., 296, 2020
|
|
6KY8
| Crystal structure of ASFV dUTPase | Descriptor: | E165R | Authors: | Li, C, Chai, Y, Song, H, Qi, J, Sun, Y, Gao, G.F. | Deposit date: | 2019-09-17 | Release date: | 2019-11-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Crystal Structure of African Swine Fever Virus dUTPase Reveals a Potential Drug Target. Mbio, 10, 2019
|
|
1F7D
| CRYSTAL STRUCTURES OF FELINE IMMUNODEFICIENCY VIRUS DUTP PYROPHOSPHATASE AND ITS NUCLEOTIDE COMPLEXES IN THREE CRYSTAL FORMS | Descriptor: | MAGNESIUM ION, POL POLYPROTEIN | Authors: | Prasad, G.S, Stura, E.A, Elder, J.H, Stout, C.D. | Deposit date: | 2000-06-26 | Release date: | 2000-09-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structures of feline immunodeficiency virus dUTP pyrophosphatase and its nucleotide complexes in three crystal forms. Acta Crystallogr.,Sect.D, 56, 2000
|
|
1F7K
| CRYSTAL STRUCTURES OF FELINE IMMUNODEFICIENCY VIRUS DUTP PYROPHOSPHATASE AND ITS NUCLEOTIDE COMPLEXES IN THREE CRYSTAL FORMS. | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, MAGNESIUM ION, POL POLYPROTEIN | Authors: | Prasad, G.S, Stura, E.A, Elder, J.H, Stout, C.D. | Deposit date: | 2000-06-27 | Release date: | 2000-09-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of feline immunodeficiency virus dUTP pyrophosphatase and its nucleotide complexes in three crystal forms. Acta Crystallogr.,Sect.D, 56, 2000
|
|
1F7N
| CRYSTAL STRUCTURES OF FELINE IMMUNODEFICIENCY VIRUS DUTP PYROPHOSPHATASE AND ITS NUCLEOTIDE COMPLEXES IN THREE CRYSTAL FORMS. | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, MAGNESIUM ION, POL POLYPROTEIN | Authors: | Prasad, G.S, Stura, E.A, Elder, J.H, Stout, C.D. | Deposit date: | 2000-06-27 | Release date: | 2000-09-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of feline immunodeficiency virus dUTP pyrophosphatase and its nucleotide complexes in three crystal forms. Acta Crystallogr.,Sect.D, 56, 2000
|
|
1F7O
| CRYSTAL STRUCTURES OF FELINE IMMUNODEFICIENCY VIRUS DUTP PYROPHOSPHATASE AND ITS NUCLEOTIDE COMPLEXES IN THREE CRYSTAL FORMS. | Descriptor: | POL POLYPROTEIN | Authors: | Prasad, G.S, Stura, E.A, Elder, J.H, Stout, C.D. | Deposit date: | 2000-06-27 | Release date: | 2000-09-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of feline immunodeficiency virus dUTP pyrophosphatase and its nucleotide complexes in three crystal forms. Acta Crystallogr.,Sect.D, 56, 2000
|
|
1F7Q
| CRYSTAL STRUCTURES OF FELINE IMMUNODEFICIENCY VIRUS DUTP PYROPHOSPHATASE AND ITS NUCLEOTIDE COMPLEXES IN THREE CRYSTAL FORMS. | Descriptor: | DEOXYURIDINE-5'-TRIPHOSPHATE, POL POLYPROTEIN | Authors: | Prasad, G.S, Stura, E.A, Elder, J.H, Stout, C.D. | Deposit date: | 2000-06-27 | Release date: | 2000-09-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Structures of feline immunodeficiency virus dUTP pyrophosphatase and its nucleotide complexes in three crystal forms. Acta Crystallogr.,Sect.D, 56, 2000
|
|
1F7R
| CRYSTAL STRUCTURES OF FELINE IMMUNODEFICIENCY VIRUS DUTP PYROPHOSPHATASE AND ITS NUCLEOTIDE COMPLEXES IN THREE CRYSTAL FORMS. | Descriptor: | MAGNESIUM ION, POL POLYPROTEIN, URIDINE-5'-DIPHOSPHATE | Authors: | Prasad, G.S, Stura, E.A, Elder, J.H, Stout, C.D. | Deposit date: | 2000-06-27 | Release date: | 2000-09-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of feline immunodeficiency virus dUTP pyrophosphatase and its nucleotide complexes in three crystal forms. Acta Crystallogr.,Sect.D, 56, 2000
|
|
1F7P
| CRYSTAL STRUCTURES OF FELINE IMMUNODEFICIENCY VIRUS DUTP PYROPHOSPHATASE AND ITS NUCLEOTIDE COMPLEXES IN THREE CRYSTAL FORMS. | Descriptor: | POL POLYPROTEIN, URIDINE-5'-DIPHOSPHATE | Authors: | Prasad, G.S, Stura, E.A, Elder, J.H, Stout, C.D. | Deposit date: | 2000-06-27 | Release date: | 2000-09-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of feline immunodeficiency virus dUTP pyrophosphatase and its nucleotide complexes in three crystal forms. Acta Crystallogr.,Sect.D, 56, 2000
|
|
2HRM
| Crystal structure of dUTPase complexed with substrate analogue methylene-dUTP | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXY-5'-O-[(S)-HYDROXY(PHOSPHONOMETHYL)PHOSPHORYL]URIDINE, Deoxyuridine 5'-triphosphate nucleotidohydrolase | Authors: | Barabas, O, Kovari, J, Tapai, R, Vertessy, B.G. | Deposit date: | 2006-07-20 | Release date: | 2007-07-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Methylene substitution at the alpha-beta bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site. Proteins, 71, 2008
|
|
2J4Q
| Crystal structure of a E138A Escherichia coli dCTP deaminase mutant enzyme in complex with dTTP | Descriptor: | DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, MAGNESIUM ION, THYMIDINE-5'-DIPHOSPHATE, ... | Authors: | Johansson, E, Thymark, M, Bynck, J.H, Fanoe, M, Larsen, S, Willemoes, M. | Deposit date: | 2006-09-05 | Release date: | 2007-08-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Regulation of Dctp Deaminase from Escherichia Coli by Nonallosteric Dttp Binding to an Inactive Form of the Enzyme FEBS J., 274, 2007
|
|
6KY9
| Crystal structure of ASFV dUTPase and UMP complex | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, E165R | Authors: | Li, C, Chai, Y, Song, H, Qi, J, Sun, Y, Gao, G.F. | Deposit date: | 2019-09-17 | Release date: | 2019-11-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of African Swine Fever Virus dUTPase Reveals a Potential Drug Target. Mbio, 10, 2019
|
|
6KZ6
| Crystal structure of ASFV dUTPase | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, E165R, MAGNESIUM ION | Authors: | Guo, Y, Chen, C, Li, G.B, Cao, L, Wang, C.W. | Deposit date: | 2019-09-23 | Release date: | 2019-11-13 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.187 Å) | Cite: | Structural Insight into African Swine Fever Virus dUTPase Reveals a Novel Folding Pattern in the dUTPase Family. J.Virol., 94, 2020
|
|
6LIS
| ASFV dUTPase in complex with dUMP | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, E165R | Authors: | Liang, R, Peng, G.Q. | Deposit date: | 2019-12-12 | Release date: | 2020-11-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.998 Å) | Cite: | Structural comparisons of host and African swine fever virus dUTPases reveal new clues for inhibitor development. J.Biol.Chem., 296, 2020
|
|
1PKH
| STRUCTURAL BASIS FOR RECOGNITION AND CATALYSIS BY THE BIFUNCTIONAL DCTP DEAMINASE AND DUTPASE FROM METHANOCOCCUS JANNASCHII | Descriptor: | 1,2-ETHANEDIOL, Bifunctional deaminase/diphosphatase | Authors: | Huffman, J.L, Li, H, White, R.H, Tainer, J.A. | Deposit date: | 2003-06-05 | Release date: | 2003-08-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Structural basis for recognition and catalysis by the bifunctional dCTP deaminase and dUTPase from Methanococcus jannaschii J.Mol.Biol., 331, 2003
|
|
2J4H
| Crystal structure of a H121A Escherichia coli dCTP deaminase mutant enzyme | Descriptor: | DEOXYCYTIDINE DIPHOSPHATE, DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, MAGNESIUM ION | Authors: | Johansson, E, Thymark, M, Bynck, J.H, Fanoe, M, Larsen, S, Willemoes, M. | Deposit date: | 2006-08-31 | Release date: | 2007-08-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Regulation of Dctp Deaminase from Escherichia Coli by Nonallosteric Dttp Binding to an Inactive Form of the Enzyme FEBS J., 274, 2007
|
|