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6UI4
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BU of 6ui4 by Molmil
Crystal structure of phenamacril-bound F. graminearum myosin I
Descriptor: Calmodulin, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Zhou, Y, Zhou, X.E, Gong, Y, Zhu, Y, Xu, H.E, Zhou, M, Melcher, K, Zhang, F.
Deposit date:2019-09-30
Release date:2020-03-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis of Fusarium myosin I inhibition by phenamacril.
Plos Pathog., 16, 2020
6TKZ
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BU of 6tkz by Molmil
Crystal structure of the DHR2 domain of DOCK10 in complex with CDC42
Descriptor: Cell division control protein 42 homolog, Dedicator of cytokinesis protein 10, GLYCEROL, ...
Authors:Barford, D.
Deposit date:2019-11-29
Release date:2020-01-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structural basis for CDC42 and RAC activation by the dual specificity GEF DOCK10
Biorxiv, 2022
2G2B
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BU of 2g2b by Molmil
NMR structure of the human allograft inflammatory factor 1
Descriptor: Allograft inflammatory factor 1
Authors:Song, J, Tyler, R.C, Newman, C.L, Vinarov, D, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2006-02-15
Release date:2006-02-28
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:NMR structure of the human allograft inflammatory factor 1
To be published
5LPU
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BU of 5lpu by Molmil
Crystal structure of Annexin A2 complexed with S100A4
Descriptor: Annexin A2, CALCIUM ION, GLYCEROL, ...
Authors:Ecsedi, P, Gogl, G, Kiss, B, Nyitray, L.
Deposit date:2016-08-15
Release date:2017-07-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding.
Structure, 25, 2017
4ITR
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BU of 4itr by Molmil
Crystal Structure of IbpAFic2-H3717A in complex with adenylylated Cdc42
Descriptor: ADENOSINE MONOPHOSPHATE, Adenosine monophosphate-protein transferase and cysteine protease IbpA, Cell division control protein 42 homolog, ...
Authors:Xiao, J, Dixon, J.E.
Deposit date:2013-01-18
Release date:2013-02-20
Last modified:2023-06-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of Fic-mediated adenylylation.
Nat.Struct.Mol.Biol., 17, 2010
3BJI
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BU of 3bji by Molmil
Structural Basis of Promiscuous Guanine Nucleotide Exchange by the T-Cell Essential Vav1
Descriptor: Proto-oncogene vav, Ras-related C3 botulinum toxin substrate 1 precursor, ZINC ION
Authors:Chrencik, J.E, Brooun, A, Kuhn, P, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)
Deposit date:2007-12-04
Release date:2008-07-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1.
J.Mol.Biol., 380, 2008
4HRE
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BU of 4hre by Molmil
Crystal Structure of p11/Annexin A2 Heterotetramer in Complex with SMARCA3 Peptide
Descriptor: Annexin A2, Helicase-like transcription factor, Protein S100-A10
Authors:Gao, P, Patel, D.J.
Deposit date:2012-10-27
Release date:2013-03-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7852 Å)
Cite:SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11-Dependent Antidepressant Action.
Cell(Cambridge,Mass.), 152, 2013
4HRH
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BU of 4hrh by Molmil
Crystal Structure of p11-Annexin A2(N-terminal) Fusion Protein in Complex with SMARCA3 Peptide
Descriptor: Helicase-like transcription factor, Protein S100-A10, Annexin A2, ...
Authors:Gao, P, Patel, D.J.
Deposit date:2012-10-27
Release date:2013-03-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11-Dependent Antidepressant Action.
Cell(Cambridge,Mass.), 152, 2013
1LKX
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BU of 1lkx by Molmil
MOTOR DOMAIN OF MYOE, A CLASS-I MYOSIN
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MYOSIN IE HEAVY CHAIN, ...
Authors:Kollmar, M, Durrwang, U, Kliche, W, Manstein, D.J, Kull, F.J.
Deposit date:2002-04-26
Release date:2002-06-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the motor domain of a class-I myosin.
EMBO J., 21, 2002
2VZG
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BU of 2vzg by Molmil
Crystal structure of the C-terminal calponin homology domain of alpha- parvin in complex with paxillin LD2 motif
Descriptor: 1,2-ETHANEDIOL, Alpha-parvin, Paxillin, ...
Authors:Lorenz, S, Vakonakis, I, Lowe, E.D, Campbell, I.D, Noble, M.E.M, Hoellerer, M.K.
Deposit date:2008-08-01
Release date:2008-10-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of the interactions between paxillin LD motifs and alpha-parvin.
Structure, 16, 2008
2VZD
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BU of 2vzd by Molmil
Crystal structure of the C-terminal calponin homology domain of alpha parvin in complex with paxillin LD1 motif
Descriptor: 1,2-ETHANEDIOL, ALPHA-PARVIN, GLYCEROL, ...
Authors:Lorenz, S, Vakonakis, I, Lowe, E.D, Campbell, I.D, Noble, M.E.M, Hoellerer, M.K.
Deposit date:2008-07-31
Release date:2008-10-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Analysis of the Interactions between Paxillin Ld Motifs and Alpha-Parvin
Structure, 16, 2008
7DHW
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BU of 7dhw by Molmil
Crystal structure of myosin-XI motor domain in complex with ADP-ALF4
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Suzuki, K, Haraguchi, T, Tamanaha, M, Yoshimura, K, Imi, T, Tominaga, M, Sakayama, H, Nishiyama, T, Ito, K, Murata, T.
Deposit date:2020-11-17
Release date:2021-05-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Discovery of ultrafast myosin, its amino acid sequence, and structural features.
Proc.Natl.Acad.Sci.USA, 119, 2022
2VZC
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BU of 2vzc by Molmil
Crystal structure of the C-terminal calponin homology domain of alpha parvin
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Lorenz, S, Vakonakis, I, Lowe, E.D, Campbell, I.D, Noble, M.E.M, Hoellerer, M.K.
Deposit date:2008-07-31
Release date:2008-10-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Structural Analysis of the Interactions between Paxillin Ld Motifs and Alpha-Parvin
Structure, 16, 2008
2VZI
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BU of 2vzi by Molmil
Crystal structure of the C-terminal calponin homology domain of alpha- parvin in complex with paxillin LD4 motif
Descriptor: 1,2-ETHANEDIOL, Alpha-parvin, Paxillin,Paxillin, ...
Authors:Lorenz, S, Vakonakis, I, Lowe, E.D, Campbell, I.D, Noble, M.E.M, Hoellerer, M.K.
Deposit date:2008-08-01
Release date:2008-10-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural analysis of the interactions between paxillin LD motifs and alpha-parvin.
Structure, 16, 2008
5N6O
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BU of 5n6o by Molmil
Wild type human Rac1-GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1
Authors:Cherfils, J, Ferrandez, Y.
Deposit date:2017-02-15
Release date:2017-12-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Allosteric inhibition of the guanine nucleotide exchange factor DOCK5 by a small molecule.
Sci Rep, 7, 2017
1PA7
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BU of 1pa7 by Molmil
Crystal structure of amino-terminal microtubule binding domain of EB1
Descriptor: Microtubule-associated protein RP/EB family member 1, SULFATE ION
Authors:Hayashi, I, Ikura, M.
Deposit date:2003-05-13
Release date:2003-10-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure of the amino-terminal microtubule-binding domain of end-binding protein 1 (EB1)
J.Biol.Chem., 278, 2003
8IW0
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BU of 8iw0 by Molmil
Crystal structure of the KANK1/liprin-beta1 complex
Descriptor: Liprin-beta-1,KN motif and ankyrin repeat domain-containing protein 1
Authors:Zhang, J, Chen, S, Wei, Z, Yu, C.
Deposit date:2023-03-29
Release date:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation.
Cell Rep, 42, 2023
3HVQ
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BU of 3hvq by Molmil
Crystal structure of a complex between Protein Phosphatase 1 alpha (PP1) and the PP1 binding and PDZ domains of Neurabin
Descriptor: GLYCEROL, MANGANESE (II) ION, Neurabin-1, ...
Authors:Critton, D.A, Ragusa, M.J, Page, R, Peti, W.
Deposit date:2009-06-16
Release date:2010-03-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites.
Nat.Struct.Mol.Biol., 17, 2010
7XQV
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BU of 7xqv by Molmil
The complex of nanobody Rh57 binding to GTP-bound RhoA active form
Descriptor: ALANINE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Zhang, Y.R, Liu, R, Ding, Y.
Deposit date:2022-05-09
Release date:2022-07-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Structural insights into the binding of nanobody Rh57 to active RhoA-GTP.
Biochem.Biophys.Res.Commun., 616, 2022
7VV9
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BU of 7vv9 by Molmil
Crystal Structure of HRas(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1
Descriptor: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Zheng, Y.Y, Zhou, C.
Deposit date:2021-11-05
Release date:2022-05-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into Ras regulation by SIN1.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VVB
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BU of 7vvb by Molmil
Crystal Structure of KRas4A(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1
Descriptor: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Zheng, Y.Y, Zhou, C.
Deposit date:2021-11-05
Release date:2022-05-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into Ras regulation by SIN1.
Proc.Natl.Acad.Sci.USA, 119, 2022
4K81
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BU of 4k81 by Molmil
Crystal structure of the Grb14 RA and PH domains in complex with GTP-loaded H-Ras
Descriptor: GLYCEROL, GTPase HRas, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Qamra, R, Hubbard, S.R.
Deposit date:2013-04-17
Release date:2013-09-04
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the interaction of the adaptor protein grb14 with activated ras.
Plos One, 8, 2013
3D9V
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BU of 3d9v by Molmil
CRYSTAL STRUCTURE OF ROCK I BOUND TO H-1152P A DI-METHYLATED VARIANT OF FASUDIL
Descriptor: (S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE, Rho-associated protein kinase 1
Authors:Jacobs, M.
Deposit date:2008-05-27
Release date:2008-06-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The structure of dimeric ROCK I reveals the mechanism for ligand selectivity.
J.Biol.Chem., 281, 2006
6R9H
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BU of 6r9h by Molmil
Crystal structure of the PDZ tandem of syntenin in complex with fragment C58
Descriptor: (2~{S})-2-[2-(4-chlorophenyl)sulfanylethanoylamino]-3-methyl-butanoic acid, ACETATE ION, PHOSPHATE ION, ...
Authors:Feracci, M, Barral, K.
Deposit date:2019-04-03
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loadifing with syndecan and EpCAM cargo.
J Extracell Vesicles, 10, 2020
6ZS2
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BU of 6zs2 by Molmil
Crystal Structure of the bromodomain of human transcription activator BRG1 (SMARCA4) in complex with 2-(6-amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol
Descriptor: 1,2-ETHANEDIOL, 2-(6-azanyl-5-piperazin-4-ium-1-yl-pyridazin-3-yl)phenol, Transcription activator BRG1
Authors:Preuss, F, Joerger, A.C, Kraemer, A, Wanior, M, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2020-07-15
Release date:2020-10-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis.
J.Med.Chem., 63, 2020

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