9C3T
 
 | | Crystal structure of DNA N6-Adenine Methyltransferase M.BceJIV from Burkholderia cenocepacia in complex with duplex DNA substrate containing GTAAAC as recognition sequence | | Descriptor: | DNA1, DNA2, Methyltransferase, ... | | Authors: | Kottur, J, Quintana-Feliciano, R, Aggarwal, A.K. | | Deposit date: | 2024-06-02 | | Release date: | 2024-09-11 | | Last modified: | 2024-09-25 | | Method: | X-RAY DIFFRACTION (2.37 Å) | | Cite: | Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation.
Nat Commun, 15, 2024
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9BOQ
 | | Human p97/VCP structure with a triazole inhibitor (NSC799462/dodecamer) | | Descriptor: | 3-(2,6-difluoro-4-{[(4P)-5-{[(2S)-hexan-2-yl]sulfanyl}-4-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]methoxy}phenyl)prop-2-yn-1-yl (1-methylpiperidin-4-yl)carbamate, ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | | Authors: | Nandi, P, DeVore, K, Chiu, P.-L. | | Deposit date: | 2024-05-05 | | Release date: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | Mechanism of allosteric inhibition of human p97/VCP ATPase and its disease mutant by triazole inhibitors.
Commun Chem, 7, 2024
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9B1G
 | | Human urate transporter 1 URAT1 in complex with dotinurad | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 22 member 12, dotinurad | | Authors: | Dai, Y, Lee, C.H. | | Deposit date: | 2024-03-13 | | Release date: | 2024-09-18 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 2024
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9EO5
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9B1I
 | | Human urate transporter 1 URAT1 in complex with verinurad | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 22 member 12, verinurad | | Authors: | Dai, Y, Lee, C.H. | | Deposit date: | 2024-03-13 | | Release date: | 2024-09-18 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 2024
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9B8Y
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9B93
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8YL5
 | | The DSR2-DSAD1 complex with DSAD1 on the same sides | | Descriptor: | DSAD1, SIR2-like domain-containing protein | | Authors: | Yang, X, Zheng, J. | | Deposit date: | 2024-03-05 | | Release date: | 2024-08-14 | | Method: | ELECTRON MICROSCOPY (3.45 Å) | | Cite: | Structural insights into autoinhibition and activation of defense-associated sirtuin protein.
Int.J.Biol.Macromol., 277, 2024
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9B1M
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9B92
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8ZTR
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9BHT
 | | Septin Hexameric Complex SEPT2/SEPT6/SEPT7 of Ciona intestinalis by Cryo-EM | | Descriptor: | CiSeptin-2, CiSeptin-6, CiSeptin-7, ... | | Authors: | Mendonca, D.C, Pereira, H.M, Garratt, R.C. | | Deposit date: | 2024-04-22 | | Release date: | 2024-07-10 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Structural Insights into Ciona intestinalis Septins: Complexes Suggest a Mechanism for Nucleotide-dependent Interfacial Cross-talk.
J.Mol.Biol., 436, 2024
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9EMU
 | | RosC-8-demethyl-8-amino-FMN - Phosphate complex | | Descriptor: | 1-deoxy-1-[8-(dimethylamino)-7-methyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl]-D-ribitol, GLYCEROL, PHOSPHATE ION, ... | | Authors: | Ermler, U, Mack, M, Demmer, U. | | Deposit date: | 2024-03-11 | | Release date: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | The Phosphatase RosC from Streptomyces davaonensis is Used for Roseoflavin Biosynthesis and has Evolved to Largely Prevent Dephosphorylation of the Important Cofactor Riboflavin-5'-phosphate.
J.Mol.Biol., 436, 2024
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9B94
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9GDM
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8YLT
 | | The structure of DSR2 and NAD+ complex | | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2-like domain-containing protein | | Authors: | Zheng, J, Yang, X. | | Deposit date: | 2024-03-06 | | Release date: | 2024-08-14 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Structural insights into autoinhibition and activation of defense-associated sirtuin protein.
Int.J.Biol.Macromol., 277, 2024
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9BHW
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9BEW
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9B91
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9B8W
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9C3S
 | | Crystal structure of DNA N6-Adenine Methyltransferase M.BceJIV from Burkholderia cenocepacia in complex with duplex DNA substrate containing GTATAC as recognition sequence | | Descriptor: | DNA1, DNA2, Methyltransferase, ... | | Authors: | Kottur, J, Quintana-Feliciano, R, Aggarwal, A.K. | | Deposit date: | 2024-06-02 | | Release date: | 2024-09-11 | | Last modified: | 2024-09-18 | | Method: | X-RAY DIFFRACTION (2.16 Å) | | Cite: | Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation.
Nat Commun, 15, 2024
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9EM8
 | | Oligomeric structure of SynDLP in presence of GDP | | Descriptor: | Slr0869 protein | | Authors: | Junglas, B, Gewehr, L, Schoennenbeck, P, Schneider, D, Sachse, C. | | Deposit date: | 2024-03-07 | | Release date: | 2024-09-11 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural basis for GTPase activity and conformational changes of the bacterial dynamin-like protein SynDLP.
Cell Rep, 43, 2024
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9C49
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9EOW
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6CHA
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