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4ZLF	Cellobionic acid phosphorylase - cellobionic acid complex Descriptor: 4-O-beta-D-glucopyranosyl-D-gluconic acid, CHLORIDE ION, GLYCEROL, ... Authors: Nam, Y.W, Arakawa, T, Fushinobu, S. Deposit date: 2015-05-01 Release date: 2015-06-10 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal Structure and Substrate Recognition of Cellobionic Acid Phosphorylase, Which Plays a Key Role in Oxidative Cellulose Degradation by Microbes. J.Biol.Chem., 290, 2015
4Z2P	Crystal structure of short hoefavidin-hoef-peptide(L9F) complex Descriptor: Avidin family, Hoef-peptide (L9F) Authors: Livnah, O, Avraham, O. Deposit date: 2015-03-30 Release date: 2015-07-15 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Hoefavidin: A dimeric bacterial avidin with a C-terminal binding tail. J.Struct.Biol., 191, 2015
4ZLE	Cellobionic acid phosphorylase - ligand free structure Descriptor: CHLORIDE ION, GLYCEROL, Putative b-glycan phosphorylase, ... Authors: Nam, Y.W, Arakawa, T, Fushinobu, S. Deposit date: 2015-05-01 Release date: 2015-06-10 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal Structure and Substrate Recognition of Cellobionic Acid Phosphorylase, Which Plays a Key Role in Oxidative Cellulose Degradation by Microbes. J.Biol.Chem., 290, 2015
5DGE	Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. Deposit date: 2015-08-27 Release date: 2017-01-25 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.45 Å) Cite: Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
4ZIL	Crystal structure of Rv2466c and oxidoreductase from Mycobacterium tuberculosis in its reduced state Descriptor: DSBA oxidoreductase, MAGNESIUM ION Authors: Albesa-Jove, D, Urresti, S, Comino, N, Tersa, M, Guerin, M.E. Deposit date: 2015-04-28 Release date: 2015-11-18 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.507 Å) Cite: The Redox State Regulates the Conformation of Rv2466c to Activate the Antitubercular Prodrug TP053. J.Biol.Chem., 290, 2015
4GM8	Crystal structure of human WD repeat domain 5 with compound MM-102 Descriptor: MM-102, WD repeat-containing protein 5 Authors: Karatas, H, Townsend, E.C, Chen, Y, Bernard, D, Cao, F, Liu, L, Lei, M, Dou, Y, Wang, S. Deposit date: 2012-08-15 Release date: 2013-07-31 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.601 Å) Cite: High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction. J.Am.Chem.Soc., 135, 2013
4Z28	Crystal structure of short hoefavidin biotin complex Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Avidin family, BIOTIN Authors: Livnah, O, Avraham, O. Deposit date: 2015-03-29 Release date: 2015-07-15 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.66 Å) Cite: Hoefavidin: A dimeric bacterial avidin with a C-terminal binding tail. J.Struct.Biol., 191, 2015
4Z6J	Crystal structure of apo intact hoefavidin Descriptor: Avidin family Authors: Livnah, O, Avraham, O. Deposit date: 2015-04-05 Release date: 2015-07-15 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Hoefavidin: A dimeric bacterial avidin with a C-terminal binding tail. J.Struct.Biol., 191, 2015
4ZFI	Structure of Mdm2 with low molecular weight inhibitor Descriptor: (5S)-3,5-bis(4-chlorobenzyl)-4-(6-chloro-1H-indol-3-yl)-5-hydroxy-1-methyl-1,5-dihydro-2H-pyrrol-2-one, E3 ubiquitin-protein ligase Mdm2 Authors: Zak, K.M, Twarda-Clapa, A, Wrona, E.M, Grudnik, P, Dubin, G, Holak, T.A. Deposit date: 2015-04-21 Release date: 2016-10-19 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2 Å) Cite: A Unique Mdm2-Binding Mode of the 3-Pyrrolin-2-one- and 2-Furanone-Based Antagonists of the p53-Mdm2 Interaction. ACS Chem. Biol., 11, 2016
4GM9	Crystal structure of human WD repeat domain 5 with compound MM-401 Descriptor: MM-401, WD repeat-containing protein 5 Authors: Karatas, H, Townsend, E.C, Chen, Y, Bernard, D, Liu, L, Dou, Y, Lei, M, Wang, S. Deposit date: 2012-08-15 Release date: 2014-02-19 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of human WD repeat domain 5 with compound MM-401 To be Published
4ZLG	Cellobionic acid phosphorylase - gluconic acid complex Descriptor: CHLORIDE ION, D-gluconic acid, D-glucono-1,5-lactone, ... Authors: Nam, Y.W, Arakawa, T, Fushinobu, S. Deposit date: 2015-05-01 Release date: 2015-06-10 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal Structure and Substrate Recognition of Cellobionic Acid Phosphorylase, Which Plays a Key Role in Oxidative Cellulose Degradation by Microbes. J.Biol.Chem., 290, 2015
4GGA	Structural Analysis of Human Cdc20 Supports Multi-site Degron Recognition by APC/C Descriptor: Cell division cycle protein 20 homolog Authors: Luo, X, Tian, W, Tomchick, D.R. Deposit date: 2012-08-06 Release date: 2012-11-07 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.044 Å) Cite: Structural analysis of human Cdc20 supports multisite degron recognition by APC/C. Proc.Natl.Acad.Sci.USA, 109, 2012
4ZOV	Crystal structure of the Saccharomyces cerevisiae Sqt1 Descriptor: Ribosome assembly protein SQT1 Authors: Pausch, P, Altegoer, F, Bange, G. Deposit date: 2015-05-07 Release date: 2015-07-01 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Co-translational capturing of nascent ribosomal proteins by their dedicated chaperones. Nat Commun, 6, 2015
5CVN	WDR48 (2-580):USP46~ubiquitin ternary complex Descriptor: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, WD repeat-containing protein 48, ... Authors: Harris, S.F, Yin, J. Deposit date: 2015-07-27 Release date: 2015-10-07 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.36 Å) Cite: Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46. Structure, 23, 2015
5D5K	Crystal Structure NLS from human PARP-2 complexed with Importin alpha delta IBB Descriptor: Importin subunit alpha-1, Poly [ADP-ribose] polymerase 2 Authors: Riccio, A.A, Cingolani, G, Pascal, J.M. Deposit date: 2015-08-10 Release date: 2016-06-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: PARP-2 domain requirements for DNA damage-dependent activation and localization to sites of DNA damage. Nucleic Acids Res., 44, 2016
4ZGK	Structure of Mdm2 with low molecular weight inhibitor. Descriptor: (5R)-3,5-bis(4-chlorobenzyl)-4-(6-chloro-1H-indol-3-yl)-5-hydroxyfuran-2(5H)-one, E3 ubiquitin-protein ligase Mdm2 Authors: Twarda-Clapa, A, Zak, K.M, Wrona, E.M, Grudnik, P, Dubin, G, Holak, T.A. Deposit date: 2015-04-23 Release date: 2016-10-19 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2 Å) Cite: A Unique Mdm2-Binding Mode of the 3-Pyrrolin-2-one- and 2-Furanone-Based Antagonists of the p53-Mdm2 Interaction. ACS Chem. Biol., 11, 2016
8IM5	Solution structure of the mouse HOIL1-L NZF domain in the free form Descriptor: RanBP-type and C3HC4-type zinc finger-containing protein 1, ZINC ION Authors: Walinda, E, Morimoto, D. Deposit date: 2023-03-06 Release date: 2023-08-30 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Solution structure of the HOIL-1L NZF domain reveals a conformational switch regulating linear ubiquitin affinity. J.Biol.Chem., 299, 2023
5DC3	Complex of yeast 80S ribosome with non-modified eIF5A Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. Deposit date: 2015-08-23 Release date: 2016-06-01 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.25 Å) Cite: Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome. J.Mol.Biol., 428, 2016
5DGV	Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analog Descriptor: 25S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... Authors: Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. Deposit date: 2015-08-28 Release date: 2016-12-14 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
5CXC	Structure of Ytm1 bound to the C-terminal domain of Erb1 in P 65 2 2 space group Descriptor: CHLORIDE ION, Ribosome biogenesis protein ERB1, Ribosome biogenesis protein YTM1 Authors: Wegrecki, M, Bravo, J. Deposit date: 2015-07-28 Release date: 2015-10-28 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.1 Å) Cite: The structure of Erb1-Ytm1 complex reveals the functional importance of a high-affinity binding between two beta-propellers during the assembly of large ribosomal subunits in eukaryotes. Nucleic Acids Res., 43, 2015
5CYK	Structure of Ytm1 bound to the C-terminal domain of Erb1-R486E Descriptor: CHLORIDE ION, Ribosome biogenesis protein ERB1, Ribosome biogenesis protein YTM1 Authors: Wegrecki, M, Bravo, J. Deposit date: 2015-07-30 Release date: 2015-10-28 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3 Å) Cite: The structure of Erb1-Ytm1 complex reveals the functional importance of a high-affinity binding between two beta-propellers during the assembly of large ribosomal subunits in eukaryotes. Nucleic Acids Res., 43, 2015
5CR2	E. coli MazF in complex with single strand DNA substrate analog Descriptor: Endoribonuclease MazF, ssDNA substrate analog Authors: Zorzini, V, Loris, R. Deposit date: 2015-07-22 Release date: 2016-04-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF. J.Biol.Chem., 291, 2016
5CQY	E. coli MazF mutant E24A in complex with MazE residues 68-82 form II Descriptor: Antitoxin MazE, Endoribonuclease MazF Authors: Zorzini, V, Loris, R. Deposit date: 2015-07-22 Release date: 2016-04-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.481 Å) Cite: Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF. J.Biol.Chem., 291, 2016
4ZH0	Structure of Helicobacter pylori adhesin BabA determined by SeMet SAD Descriptor: Outer membrane protein-adhesin Authors: Howard, T.D, Hage, N, Phillips, C, Brassington, C.A, Debreczeni, J, Overman, R, Gellert, P, Stolnik, S, Winkler, G.S, Falcone, F.H. Deposit date: 2015-04-24 Release date: 2015-08-19 Last modified: 2015-12-09 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Structural basis of Lewis(b) antigen binding by the Helicobacter pylori adhesin BabA. Sci Adv, 1, 2015
4U50	Crystal structure of Verrucarin bound to the yeast 80S ribosome Descriptor: (4S,5R,10E,12Z,16R,16aS,17S,18R,19aR,23aR)-4-hydroxy-5,16a,21-trimethyl-4,5,6,7,16,16a,22,23-octahydro-3H,18H,19aH-spiro[16,18-methano[1,6,12]trioxacyclooctadecino[3,4-d]chromene-17,2'-oxirane]-3,9,14-trione, 18S ribosomal RNA, 25S ribosomal RNA, ... Authors: Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. Deposit date: 2014-07-24 Release date: 2014-10-22 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014

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