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3U85
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BU of 3u85 by Molmil
Crystal structure of human menin in complex with MLL1
Descriptor: Histone-lysine N-methyltransferase 2A, Menin
Authors:Huang, J, Wan, B, Lei, M.
Deposit date:2011-10-15
Release date:2012-02-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
2AGH
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BU of 2agh by Molmil
Structural basis for cooperative transcription factor binding to the CBP coactivator
Descriptor: Crebbp protein, Myb proto-oncogene protein, Zinc finger protein HRX
Authors:De Guzman, R.N, Goto, N.K, Dyson, H.J, Wright, P.E.
Deposit date:2005-07-26
Release date:2005-11-22
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural Basis for Cooperative Transcription Factor Binding to the CBP Coactivator
J.Mol.Biol., 355, 2006
2B5X
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BU of 2b5x by Molmil
Solution Structure of a Thioredoxin-like Protein in the Reduced Form
Descriptor: YkuV protein
Authors:Zhang, X, Xia, B, Jin, C.
Deposit date:2005-09-29
Release date:2006-01-17
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The bacillus subtilis YKUV is a thiol-disulfide oxidoreductase revealed by its redox structures and activity
J.Biol.Chem., 281, 2006
2B5Y
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BU of 2b5y by Molmil
Solution Structure of a Thioredoxin-like Protein in the Oxidized Form
Descriptor: YkuV protein
Authors:Zhang, X, Xia, B, Jin, C.
Deposit date:2005-09-29
Release date:2006-01-17
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:The bacillus subtilis YKUV is a thiol-disulfide oxidoreductase revealed by its redox structures and activity
J.Biol.Chem., 281, 2006
2YOI
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BU of 2yoi by Molmil
Crystal Structure of Ancestral Thioredoxin Relative to Last Eukaryotes Common Ancestor (LECA) from the Precambrian Period
Descriptor: ACETATE ION, CHLORIDE ION, LECA THIOREDOXIN, ...
Authors:Gavira, J.A, Ingles-Prieto, A, Ibarra-Molero, B, Sanchez-Ruiz, J.M.
Deposit date:2012-10-24
Release date:2013-08-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Conservation of protein structure over four billion years.
Structure, 21, 2013
2YN1
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BU of 2yn1 by Molmil
Crystal Structure of Ancestral Thioredoxin Relative to Last Gamma- Proteobacteria Common Ancestor (LGPCA) from the Precambrian Period
Descriptor: LGPCA THIOREDOXIN, TRIETHYLENE GLYCOL
Authors:Gavira, J.A, Ingles-Prieto, A, Ibarra-Molero, B, Sanchez-Ruiz, J.M.
Deposit date:2012-10-11
Release date:2013-08-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Conservation of Protein Structure Over Four Billion Years
Structure, 21, 2013
3OUE
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BU of 3oue by Molmil
Structure of C-terminal hexaheme fragment of GSU1996
Descriptor: Cytochrome c family protein, HEME C, SULFATE ION
Authors:Pokkuluri, P.R, Schiffer, M.
Deposit date:2010-09-14
Release date:2010-12-29
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of a novel dodecaheme cytochrome c from Geobacter sulfurreducens reveals an extended 12nm protein with interacting hemes.
J.Struct.Biol., 174, 2011
5NPL
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BU of 5npl by Molmil
Crystal structure of hexameric CBS-CP12 protein from bloom-forming cyanobacteria, Yb-derivative at 2.8 A resolution
Descriptor: 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID, Similar to tr|Q8YYT1|Q8YYT1, YTTERBIUM (III) ION
Authors:Hackenberg, C, Hakanpaa, J, Antonyuk, S.V, Dittmann, E, Lamzin, V.S.
Deposit date:2017-04-17
Release date:2018-05-30
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural and functional insights into the unique CBS-CP12 fusion protein family in cyanobacteria.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5NMU
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BU of 5nmu by Molmil
Structure of hexameric CBS-CP12 protein from bloom-forming cyanobacteria
Descriptor: CBS-CP12, CHLORIDE ION
Authors:Hackenberg, C, Hakanpaa, J, Antonyuk, S.V, Dittmann, E, Lamzin, V.S.
Deposit date:2017-04-07
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and functional insights into the unique CBS-CP12 fusion protein family in cyanobacteria.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4NI2
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BU of 4ni2 by Molmil
Crystal structure of the heterodimeric catalytic domain of wild-type human soluble guanylate cyclase
Descriptor: 1,2-ETHANEDIOL, Guanylate cyclase soluble subunit alpha-3, Guanylate cyclase soluble subunit beta-1
Authors:Seeger, F, Williams, G.J, Tainer, J.A, Garcin, E.D.
Deposit date:2013-11-05
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Interfacial residues promote an optimal alignment of the catalytic center in human soluble guanylate cyclase: heterodimerization is required but not sufficient for activity.
Biochemistry, 53, 2014
5NVD
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BU of 5nvd by Molmil
Crystal structure of hexameric CBS-CP12 protein from bloom-forming cyanobacteria at 2.5 A resolution in P6322 crystal form
Descriptor: CBS-CP12
Authors:Hackenberg, C, Hakanpaa, J, Eigner, C, Antonyuk, S.V, Dittmann, E, Lamzin, V.S.
Deposit date:2017-05-04
Release date:2018-05-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and functional insights into the unique CBS-CP12 fusion protein family in cyanobacteria.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2YJ7
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BU of 2yj7 by Molmil
Crystal structure of a hyperstable protein from the Precambrian period
Descriptor: LPBCA THIOREDOXIN, SODIUM ION
Authors:Gavira, J.A, Ingles, A, Ibarra, B, Garcia-Ruiz, J.M.
Deposit date:2011-05-19
Release date:2012-05-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Conservation of Protein Structure Over Four Billion Years
Structure, 21, 2013
2XD7
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BU of 2xd7 by Molmil
Crystal structure of the macro domain of human core histone H2A
Descriptor: CORE HISTONE MACRO-H2A.2
Authors:Vollmar, M, Phillips, C, Carpenter, E.P, Muniz, J.R.C, Krojer, T, Ugochukwu, E, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Gileadi, O.
Deposit date:2010-04-29
Release date:2010-05-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Crystal Structure of the Macro Domain of Human Core Histone H2A
To be Published
4N82
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BU of 4n82 by Molmil
X-ray crystal structure of Streptococcus sanguinis NrdIox
Descriptor: FLAVIN MONONUCLEOTIDE, Ribonucleotide reductase, SULFATE ION
Authors:Boal, A.K, Rosenzweig, A.C.
Deposit date:2013-10-16
Release date:2014-01-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Streptococcus sanguinis Class Ib Ribonucleotide Reductase: HIGH ACTIVITY WITH BOTH IRON AND MANGANESE COFACTORS AND STRUCTURAL INSIGHTS.
J.Biol.Chem., 289, 2014
2YNX
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BU of 2ynx by Molmil
Crystal Structure of Ancestral Thioredoxin Relative to Last Archaea Common Ancestor (LACA) from the Precambrian Period
Descriptor: ACETATE ION, LACA THIOREDOXIN, SODIUM ION
Authors:Gavira, J.A, Ingles-Prieto, A, Ibarra-Molero, B, Sanchez-Ruiz, J.M.
Deposit date:2012-10-19
Release date:2013-08-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.749 Å)
Cite:Conservation of Protein Structure Over Four Billion Years
Structure, 21, 2013
4N83
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BU of 4n83 by Molmil
X-ray crystal structure of Streptococcus sanguinis dimanganese(II)-NrdF
Descriptor: MANGANESE (II) ION, Ribonucleoside-diphosphate reductase subunit beta
Authors:Boal, A.K, Rosenzweig, A.C.
Deposit date:2013-10-16
Release date:2014-01-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Streptococcus sanguinis Class Ib Ribonucleotide Reductase: HIGH ACTIVITY WITH BOTH IRON AND MANGANESE COFACTORS AND STRUCTURAL INSIGHTS.
J.Biol.Chem., 289, 2014
4NW3
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BU of 4nw3 by Molmil
Crystal structure of MLL CXXC domain in complex with a CpG DNA
Descriptor: 5'-D(*GP*CP*CP*AP*TP*CP*GP*AP*TP*GP*GP*C)-3', Histone-lysine N-methyltransferase 2A, ZINC ION
Authors:Bian, C, Tempel, W, Chao, X, Walker, J.R, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2013-12-05
Release date:2014-04-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Structure, 26, 2018
4BA7
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BU of 4ba7 by Molmil
Crystal Structure of Ancestral Thioredoxin Relative to Last Bacteria Common Ancestor (LBCA) from the Precambrian Period
Descriptor: 1,2-ETHANEDIOL, LBCA THIOREDOXIN
Authors:Gavira, J.A, Ingles-Prieto, A, Ibarra-Molero, B, Sanchez-Ruiz, J.M.
Deposit date:2012-09-12
Release date:2013-08-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Conservation of Protein Structure Over Four Billion Years
Structure, 21, 2013
4HUA
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BU of 4hua by Molmil
E. coli thioredoxin variant with (4R)-FluoroPro76 as single proline residue
Descriptor: COPPER (II) ION, Thioredoxin-1
Authors:Scharer, M.A, Rubini, M, Capitani, G, Glockshuber, R.
Deposit date:2012-11-02
Release date:2013-05-29
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:(4R)- and (4S)-Fluoroproline in the Conserved cis-Prolyl Peptide Bond of the Thioredoxin Fold: Tertiary Structure Context Dictates Ring Puckering.
Chembiochem, 14, 2013
4HU9
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BU of 4hu9 by Molmil
E. coli thioredoxin variant with (4S)-FluoroPro76 as single proline residue
Descriptor: COPPER (II) ION, Thioredoxin-1
Authors:Scharer, M.A, Rubini, M, Capitani, G, Glockshuber, R.
Deposit date:2012-11-02
Release date:2013-05-29
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:(4R)- and (4S)-Fluoroproline in the Conserved cis-Prolyl Peptide Bond of the Thioredoxin Fold: Tertiary Structure Context Dictates Ring Puckering.
Chembiochem, 14, 2013
4JN9
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BU of 4jn9 by Molmil
Crystal structure of the DepH
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DepH, ...
Authors:Li, J, Wang, C, Zhang, Z.M, Zhou, J.H, Cheng, E.
Deposit date:2013-03-14
Release date:2014-04-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structural basis of an NADP+-independent dithiol oxidase in FK228 biosynthesis.
Sci Rep, 4, 2014
3DXC
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BU of 3dxc by Molmil
Crystal structure of the intracellular domain of human APP in complex with Fe65-PTB2
Descriptor: Amyloid beta A4 protein, Amyloid beta A4 protein-binding family B member 1
Authors:Radzimanowski, J, Sinning, I, Wild, K.
Deposit date:2008-07-24
Release date:2008-09-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.
Embo Rep., 9, 2008
3DXD
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BU of 3dxd by Molmil
Crystal structure of the intracellular domain of human APP (T668E mutant) in complex with Fe65-PTB2
Descriptor: Amyloid beta A4 protein, Amyloid beta A4 protein-binding family B member 1
Authors:Radzimanowski, J, Sinning, I, Wild, K.
Deposit date:2008-07-24
Release date:2008-09-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.
Embo Rep., 9, 2008
3DXE
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BU of 3dxe by Molmil
Crystal structure of the intracellular domain of human APP (T668A mutant) in complex with Fe65-PTB2
Descriptor: Amyloid beta A4 protein, Amyloid beta A4 protein-binding family B member 1
Authors:Radzimanowski, J, Sinning, I, Wild, K.
Deposit date:2008-07-24
Release date:2008-09-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.
Embo Rep., 9, 2008
4JNA
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BU of 4jna by Molmil
Crystal structure of the DepH complex with dimethyl-FK228
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DepH, ...
Authors:Li, J, Wang, C, Zhang, Z.M, Zhou, J.H, Cheng, E.
Deposit date:2013-03-14
Release date:2014-03-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structural basis of an NADP+-independent dithiol oxidase in FK228 biosynthesis.
Sci Rep, 4, 2014

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