7D17
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![BU of 7d17 by Molmil](/molmil-images/mine/7d17) | Crystal structure of Macrostomum lignano glutaminyl cyclase | Descriptor: | Glutaminyl-peptide cyclotransferase, ZINC ION | Authors: | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | Deposit date: | 2020-09-14 | Release date: | 2021-04-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.998 Å) | Cite: | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes. J.Mol.Biol., 433, 2021
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7D1E
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![BU of 7d1e by Molmil](/molmil-images/mine/7d1e) | Crystal structure of Bacteroides thetaiotaomicron glutaminyl cyclase bound to N-acetylhistamine | Descriptor: | Leucine aminopeptidase, N-[2-(1H-IMIDAZOL-4-YL)ETHYL]ACETAMIDE, ZINC ION | Authors: | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | Deposit date: | 2020-09-14 | Release date: | 2021-04-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes. J.Mol.Biol., 433, 2021
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7BR9
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![BU of 7br9 by Molmil](/molmil-images/mine/7br9) | Crystal structure of mus musculus IRG1 | Descriptor: | Cis-aconitate decarboxylase | Authors: | Park, H.H, Chun, H.L. | Deposit date: | 2020-03-27 | Release date: | 2021-02-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | The crystal structure of mouse IRG1 suggests that cis-aconitate decarboxylase has an open and closed conformation. Plos One, 15, 2020
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3N2X
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![BU of 3n2x by Molmil](/molmil-images/mine/3n2x) | Crystal structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12 in complex with pyruvate | Descriptor: | 1,2-ETHANEDIOL, Uncharacterized protein yagE | Authors: | Bhaskar, V, Kumar, P.M, Manicka, S, Krishnaswamy, S. | Deposit date: | 2010-05-19 | Release date: | 2011-04-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Identification of biochemical and putative biological role of a xenolog from Escherichia coli using structural analysis. Proteins, 79, 2011
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6TV2
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![BU of 6tv2 by Molmil](/molmil-images/mine/6tv2) | Heme d1 biosynthesis associated Protein NirF | Descriptor: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, GLYCEROL, Protein NirF, ... | Authors: | Kluenemann, T, Layer, G, Blankenfeldt, W. | Deposit date: | 2020-01-08 | Release date: | 2020-04-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.561 Å) | Cite: | Crystal structure of NirF: insights into its role in heme d 1 biosynthesis. Febs J., 288, 2021
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1HLY
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![BU of 1hly by Molmil](/molmil-images/mine/1hly) | SOLUTION STRUCTURE OF HONGOTOXIN 1 | Descriptor: | HONGOTOXIN 1 | Authors: | Pragl, B, Koschak, A, Trieb, M, Obermair, G, Kaufmann, W.A, Gerster, U, Blanc, E, Hahn, C, Prinz, H, Schutz, G, Darbon, H, Gruber, H.J, Knaus, H.G. | Deposit date: | 2000-12-04 | Release date: | 2003-09-30 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Synthesis, characterization, and application of cy-dye- and alexa-dye-labeled hongotoxin(1) analogues. The
first high affinity fluorescence probes for voltage-gated K+ channels. BIOCONJUG.CHEM., 13, 2002
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3NEV
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![BU of 3nev by Molmil](/molmil-images/mine/3nev) | Crystal structure of YagE, a prophage protein from E. coli K12 in complex with KDGal | Descriptor: | 1,2-ETHANEDIOL, 3-DEOXY-D-LYXO-HEXONIC ACID, Uncharacterized protein yagE | Authors: | Bhaskar, V, Kumar, P.M, Manicka, S, Krishnaswamy, S. | Deposit date: | 2010-06-09 | Release date: | 2011-04-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Identification of biochemical and putative biological role of a xenolog from Escherichia coli using structural analysis. Proteins, 79, 2011
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6TYR
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![BU of 6tyr by Molmil](/molmil-images/mine/6tyr) | |
6TV9
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![BU of 6tv9 by Molmil](/molmil-images/mine/6tv9) | |
6T65
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![BU of 6t65 by Molmil](/molmil-images/mine/6t65) | |
3N2C
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![BU of 3n2c by Molmil](/molmil-images/mine/3n2c) | Crystal structure of prolidase eah89906 complexed with n-methylphosphonate-l-proline | Descriptor: | 1-[(R)-hydroxy(methyl)phosphoryl]-L-proline, PROLIDASE, ZINC ION | Authors: | Patskovsky, Y, Xu, C, Sauder, J.M, Burley, S.K, Raushel, F.M, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-05-17 | Release date: | 2010-06-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Functional identification and structure determination of two novel prolidases from cog1228 in the amidohydrolase superfamily . Biochemistry, 49, 2010
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7CYG
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![BU of 7cyg by Molmil](/molmil-images/mine/7cyg) | Crystal structure of a cysteine-pair mutant (Y113C-P190C) of a bacterial bile acid transporter before disulfide bond formation | Descriptor: | Transporter, sodium/bile acid symporter family | Authors: | Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. | Deposit date: | 2020-09-03 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.198 Å) | Cite: | An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter. Acta Crystallogr D Struct Biol, 77, 2021
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6UBQ
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![BU of 6ubq by Molmil](/molmil-images/mine/6ubq) | |
6UCW
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![BU of 6ucw by Molmil](/molmil-images/mine/6ucw) | Multi-conformer model of Apo Ketosteroid Isomerase from Pseudomonas Putida (pKSI) at 250 K | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Steroid Delta-isomerase | Authors: | Yabukarski, F, Herschlag, D, Biel, J.T, Fraser, J.S. | Deposit date: | 2019-09-17 | Release date: | 2020-09-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Assessment of enzyme active site positioning and tests of catalytic mechanisms through X-ray-derived conformational ensembles. Proc.Natl.Acad.Sci.USA, 117, 2020
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7CYK
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![BU of 7cyk by Molmil](/molmil-images/mine/7cyk) | Crystal structure of a second cysteine-pair mutant (V110C-I197C) of a bacterial bile acid transporter before disulfide bond formation | Descriptor: | MERCURY (II) ION, Transporter, sodium/bile acid symporter family | Authors: | Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. | Deposit date: | 2020-09-03 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.785 Å) | Cite: | An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter. Acta Crystallogr D Struct Biol, 77, 2021
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3FSJ
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![BU of 3fsj by Molmil](/molmil-images/mine/3fsj) | Crystal structure of benzoylformate decarboxylase in complex with the inhibitor MBP | Descriptor: | 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-{(S)-hydroxy[(R)-hydroxy(methoxy)phosphoryl]phenylmethyl}-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, Benzoylformate decarboxylase, CALCIUM ION | Authors: | Brandt, G.S, Kenyon, G.L, McLeish, M.J, Jordan, F, Petsko, G.A, Ringe, D. | Deposit date: | 2009-01-09 | Release date: | 2009-01-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | Snapshot of a reaction intermediate: analysis of benzoylformate decarboxylase in complex with a benzoylphosphonate inhibitor. Biochemistry, 48, 2009
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6U4I
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![BU of 6u4i by Molmil](/molmil-images/mine/6u4i) | |
6TZD
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![BU of 6tzd by Molmil](/molmil-images/mine/6tzd) | |
6U1Z
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![BU of 6u1z by Molmil](/molmil-images/mine/6u1z) | |
8PJ0
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![BU of 8pj0 by Molmil](/molmil-images/mine/8pj0) | Pseudomonas aeruginosa FabF C164A mutant in complex with N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-methylbutanamide | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, FORMIC ACID, ... | Authors: | Georgiou, C, Brenk, R, Espeland, L.O. | Deposit date: | 2023-06-22 | Release date: | 2024-02-21 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Design, quality and validation of the EU-OPENSCREEN fragment library poised to a high-throughput screening collection. Rsc Med Chem, 15, 2024
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3NRC
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![BU of 3nrc by Molmil](/molmil-images/mine/3nrc) | Crystal Structure of the Francisella tularensis enoyl-acyl carrier protein reductase (FabI) in complex with NAD+ and triclosan | Descriptor: | Enoyl-[acyl-carrier-protein] reductase (NADH), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN | Authors: | Mehboob, S, Santarsiero, B.D, Truong, K, Johnson, M.E. | Deposit date: | 2010-06-30 | Release date: | 2010-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.101 Å) | Cite: | Structure of the Francisella tularensis enoyl-acyl carrier protein reductase (FabI) in complex with NAD(+) and triclosan. Acta Crystallogr.,Sect.F, 66, 2010
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5C04
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![BU of 5c04 by Molmil](/molmil-images/mine/5c04) | |
5F3H
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![BU of 5f3h by Molmil](/molmil-images/mine/5f3h) | Structure of myostatin in complex with humanized RK35 antibody | Descriptor: | Growth/differentiation factor 8, humanized RK35 antibody heavy chain, humanized RK35 antibody light chain | Authors: | Parris, K.D, Mosyak, L. | Deposit date: | 2015-12-02 | Release date: | 2016-09-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Beyond CDR-grafting: Structure-guided humanization of framework and CDR regions of an anti-myostatin antibody. Mabs, 8, 2016
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5W8W
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![BU of 5w8w by Molmil](/molmil-images/mine/5w8w) | Bacillus cereus Zn-dependent metallo-beta-lactamase at pH 7 - new refinement | Descriptor: | Metallo-beta-lactamase type 2, SULFATE ION, UNKNOWN ATOM OR ION, ... | Authors: | Gonzalez, J.M, Shabalin, I.G, Raczynska, J.E, Jaskolski, M, Minor, W, Wlodawer, A, Gonzalez, M.M, Vila, A.J. | Deposit date: | 2017-06-22 | Release date: | 2017-07-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | A close look onto structural models and primary ligands of metallo-beta-lactamases. Drug Resist. Updat., 40, 2018
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5F3B
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![BU of 5f3b by Molmil](/molmil-images/mine/5f3b) | Structure of myostatin in complex with chimeric RK35 antibody | Descriptor: | GLYCEROL, Growth/differentiation factor 8, RK35 Chimeric antibody heavy chain, ... | Authors: | Parris, K.D, Mosyak, L. | Deposit date: | 2015-12-02 | Release date: | 2016-09-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Beyond CDR-grafting: Structure-guided humanization of framework and CDR regions of an anti-myostatin antibody. Mabs, 8, 2016
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