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2GRO
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BU of 2gro by Molmil
Crystal Structure of human RanGAP1-Ubc9-N85Q
Descriptor: Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I
Authors:Yunus, A.A, Lima, C.D.
Deposit date:2006-04-24
Release date:2006-05-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.
Nat.Struct.Mol.Biol., 13, 2006
2NOE
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BU of 2noe by Molmil
Structure of catalytically inactive G42A human 8-oxoguanine glycosylase complexed to 8-oxoguanine DNA
Descriptor: 5'-D(*G*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*G*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ...
Authors:Radom, C.T, Banerjee, A, Verdine, G.L.
Deposit date:2006-10-25
Release date:2006-11-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.
J.Biol.Chem., 282, 2007
7M05
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BU of 7m05 by Molmil
CryoEM structure of PRMT5 bound to covalent PBM-site inhibitor BRD-6988
Descriptor: 2-(5-chloro-6-oxopyridazin-1(6H)-yl)-N-(4-methyl-3-{[2-(pyridin-2-yl)ethyl]sulfamoyl}phenyl)acetamide, Methylosome protein 50, Protein arginine N-methyltransferase 5
Authors:McMillan, B.J, McKinney, D.C, Timm, D.E.
Deposit date:2021-03-10
Release date:2021-03-17
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (2.39 Å)
Cite:Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor Interaction.
J.Med.Chem., 64, 2021
3QEW
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BU of 3qew by Molmil
RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dDTP Opposite dT
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
Authors:Xia, S, Konigsberg, W.H, Wang, J.
Deposit date:2011-01-20
Release date:2012-01-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Hydrogen-Bonding Capability of Difluorotoluene Nucleoside in Replication Complexes
To be Published
2HN7
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BU of 2hn7 by Molmil
HLA-A*1101 in complex with HBV peptide homologue
Descriptor: Beta-2-microglobulin, DNA polymerase PEPTIDE HOMOLOGUE, HLA class I histocompatibility antigen, ...
Authors:Blicher, T.
Deposit date:2006-07-12
Release date:2006-11-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of HLA-A*1101 in complex with a hepatitis B peptide homologue.
Acta Crystallogr.,Sect.F, 62, 2006
2HSH
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BU of 2hsh by Molmil
Crystal structure of C73S mutant of human thioredoxin-1 oxidized with H2O2
Descriptor: PHOSPHATE ION, Thioredoxin
Authors:Weichsel, A, Montfort, W.R.
Deposit date:2006-07-21
Release date:2006-12-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Buried s-nitrosocysteine revealed in crystal structures of human thioredoxin.
Biochemistry, 46, 2007
2HXK
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BU of 2hxk by Molmil
Crystal structure of S-nitroso thioredoxin
Descriptor: ETHANOL, Thioredoxin
Authors:Weichsel, A, Montfort, W.R.
Deposit date:2006-08-03
Release date:2006-12-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Buried s-nitrosocysteine revealed in crystal structures of human thioredoxin.
Biochemistry, 46, 2007
7V4B
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BU of 7v4b by Molmil
Heparin-induced alpha-synuclein fibrils polymorph 3
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Sun, Y.P, Liu, C, Li, D.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Heparin-induced alpha-synuclein fibrils polymorph 3
To Be Published
7V4C
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BU of 7v4c by Molmil
Heparin-induced alpha-synuclein fibrils polymorph 4
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Sun, Y.P, Liu, C, Li, D.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Heparin-induced alpha-synuclein fibrils polymorph 4
To Be Published
7V47
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BU of 7v47 by Molmil
Type 1A alpha-synuclein fibril seeded by cerebrospinal fluid from a preclinical Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7V4A
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BU of 7v4a by Molmil
Heparin-induced alpha-synuclein fibrils polymorph 1
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Sun, Y.P, Liu, C, Li, D.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Heparin-induced alpha-synuclein fibrils polymorph 1
To Be Published
7V48
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BU of 7v48 by Molmil
Type 1D alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7V4D
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BU of 7v4d by Molmil
Heparin-remodelled alpha-synuclein fibrils
Descriptor: Alpha-synuclein
Authors:Tao, Y.Q, Sun, Y.P, Xia, W.C, Zhao, Q.Y, Liu, C, Li, D.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Heparin-remodelled alpha-synuclein fibrils
To Be Published
4X60
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BU of 4x60 by Molmil
Crystal structure of PRMT5:MEP50 with EPZ015666 and sinefungin
Descriptor: GLYCEROL, Methylosome protein 50, N-[(2S)-3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl]-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide, ...
Authors:Boriack-Sjodin, P.A.
Deposit date:2014-12-06
Release date:2015-04-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models.
Nat.Chem.Biol., 11, 2015
7V49
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BU of 7v49 by Molmil
Type 4 alpha-synuclein fibril seeded by cerebrospinal fluid from a postmortal Parkinson's disease patient
Descriptor: Alpha-synuclein
Authors:Fan, Y, Sun, Y.P, Wang, J, Liu, C.
Deposit date:2021-08-12
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
5EZ6
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BU of 5ez6 by Molmil
Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA
Authors:Yan, Z, Ma, S, Zhang, Y, Ma, L, Wang, F, Li, J, Miao, L.
Deposit date:2015-11-26
Release date:2016-12-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA
To Be Published
3OCI
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BU of 3oci by Molmil
Crystal structure of TBP (TATA box binding protein)
Descriptor: 1,2-ETHANEDIOL, TRANSCRIPTION INITIATION FACTOR TFIID (TFIID-1)
Authors:Cui, S, Wollmann, P, Moldt, M, Hopfner, K.-P.
Deposit date:2010-08-10
Release date:2011-07-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP.
Nature, 475, 2011
8CZ2
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BU of 8cz2 by Molmil
CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case VII
Descriptor: Alpha-synuclein
Authors:Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
Deposit date:2022-05-24
Release date:2023-05-31
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published
8CZ6
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BU of 8cz6 by Molmil
CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case X
Descriptor: Alpha-synuclein
Authors:Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
Deposit date:2022-05-24
Release date:2023-05-31
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published
8CYX
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BU of 8cyx by Molmil
CryoEM structure of amplified alpha-synuclein fibril class A type I with compact core from DLB case III
Descriptor: Alpha-synuclein
Authors:Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
Deposit date:2022-05-24
Release date:2023-05-31
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published
8CZ0
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BU of 8cz0 by Molmil
CryoEM structure of amplified alpha-synuclein fibril class B type I with extended core from DLB case VII
Descriptor: Alpha-synuclein
Authors:Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
Deposit date:2022-05-24
Release date:2023-05-31
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published
8CYR
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BU of 8cyr by Molmil
Alpha-synuclein fibril from spontaneous control
Descriptor: Alpha-synuclein
Authors:Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
Deposit date:2022-05-24
Release date:2023-05-31
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Distinct cryo-EM structures and functions of alpha-synuclein fibrils amplified from cerebrospinal fluid
To Be Published
8CYW
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BU of 8cyw by Molmil
CryoEM structures of amplified alpha-synuclein fibril class B type I with compact core from DLB case III
Descriptor: Alpha-synuclein
Authors:Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
Deposit date:2022-05-24
Release date:2023-05-31
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published
8CYT
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BU of 8cyt by Molmil
CryoEM structures of amplified alpha-synuclein fibril class A type I with extended core from DLB case I
Descriptor: Alpha-synuclein
Authors:Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
Deposit date:2022-05-24
Release date:2023-05-31
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published
8CZ3
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BU of 8cz3 by Molmil
CryoEM structure of amplified alpha-synuclein fibril class B type I with extended core from DLB case X
Descriptor: Alpha-synuclein
Authors:Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
Deposit date:2022-05-24
Release date:2023-05-31
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published

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PDB entries from 2024-09-11

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