2H03
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![BU of 2h03 by Molmil](/molmil-images/mine/2h03) | Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors | Descriptor: | (4-{4-[(TERT-BUTOXYCARBONYL)AMINO]-2,2-BIS(ETHOXYCARBONYL)BUTYL}PHENYL)SULFAMIC ACID, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Evdokimov, A.G, Pokross, M.E, Walter, R.L, Mekel, M, Gray, J.L, Peters, K.G, Maier, M.B, Amarasinghe, K.D, Clark, C.M, Nichols, R. | Deposit date: | 2006-05-13 | Release date: | 2006-06-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta. Bioorg.Med.Chem.Lett., 16, 2006
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4DAM
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![BU of 4dam by Molmil](/molmil-images/mine/4dam) | Crystal structure of small single-stranded DNA-binding protein from Streptomyces coelicolor | Descriptor: | Single-stranded DNA-binding protein 1 | Authors: | Filic, Z, Herron, P, Ivic, N, Luic, M, Manjasetty, B.A, Paradzik, T, Vujaklija, D. | Deposit date: | 2012-01-13 | Release date: | 2013-01-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure-function relationships of two paralogous single-stranded DNA-binding proteins from Streptomyces coelicolor: implication of SsbB in chromosome segregation during sporulation. Nucleic Acids Res., 41, 2013
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4EK0
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![BU of 4ek0 by Molmil](/molmil-images/mine/4ek0) | Initial Thaumatin Structure for Radiation Damage Experiment at 25 K | Descriptor: | L(+)-TARTARIC ACID, Thaumatin-1 | Authors: | Warkentin, M, Badeau, R, Hopkins, J.B, Thorne, R.E. | Deposit date: | 2012-04-08 | Release date: | 2012-08-29 | Last modified: | 2013-01-23 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Spatial distribution of radiation damage to crystalline proteins at 25-300 K. Acta Crystallogr.,Sect.D, 68, 2012
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4EKH
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![BU of 4ekh by Molmil](/molmil-images/mine/4ekh) | Final Thaumatin Structure for Radiation Damage Experiment at 100 K | Descriptor: | L(+)-TARTARIC ACID, Thaumatin-1 | Authors: | Warkentin, M, Badeau, R, Hopkins, J.B, Thorne, R.E. | Deposit date: | 2012-04-09 | Release date: | 2012-08-29 | Last modified: | 2013-01-23 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Spatial distribution of radiation damage to crystalline proteins at 25-300 K. Acta Crystallogr.,Sect.D, 68, 2012
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4ELA
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![BU of 4ela by Molmil](/molmil-images/mine/4ela) | Final Thaumatin Structure for Radiation Damage Experiment at 300 K | Descriptor: | L(+)-TARTARIC ACID, Thaumatin-1 | Authors: | Warkentin, M, Badeau, R, Hopkins, J.B, Thorne, R.E. | Deposit date: | 2012-04-10 | Release date: | 2012-08-29 | Last modified: | 2013-01-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Spatial distribution of radiation damage to crystalline proteins at 25-300 K. Acta Crystallogr.,Sect.D, 68, 2012
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5OF2
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![BU of 5of2 by Molmil](/molmil-images/mine/5of2) | The structural versatility of TasA in B. subtilis biofilm formation | Descriptor: | 1,2-ETHANEDIOL, SULFATE ION, Spore coat-associated protein N | Authors: | Roske, Y, Diehl, A, Ball, L, Chowdhury, A, Hiller, M, Moliere, N, Kramer, R, Nagaraj, M, Stoeppler, D, Worth, C.L, Schlegel, B, Leidert, M, Cremer, N, Eisenmenger, F, Lopez, D, Schmieder, P, Heinemann, U, Turgay, K, Akbey, U, Oschkinat, H. | Deposit date: | 2017-07-10 | Release date: | 2018-03-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structural changes of TasA in biofilm formation ofBacillus subtilis. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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2GS0
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![BU of 2gs0 by Molmil](/molmil-images/mine/2gs0) | NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and the activation domain of p53 | Descriptor: | Cellular tumor antigen p53, RNA polymerase II transcription factor B subunit 1 | Authors: | Di Lello, P, Jones, T.N, Nguyen, B.D, Legault, P, Omichinski, J.G. | Deposit date: | 2006-04-25 | Release date: | 2006-10-31 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53. Mol.Cell, 22, 2006
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4EPD
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![BU of 4epd by Molmil](/molmil-images/mine/4epd) | Initial Urease Structure for Radiation Damage Experiment at 300 K | Descriptor: | NICKEL (II) ION, Urease subunit alpha, Urease subunit beta, ... | Authors: | Warkentin, M, Badeau, R, Hopkins, J.B, Thorne, R.E. | Deposit date: | 2012-04-17 | Release date: | 2012-08-29 | Last modified: | 2013-01-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Spatial distribution of radiation damage to crystalline proteins at 25-300 K. Acta Crystallogr.,Sect.D, 68, 2012
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1L1L
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![BU of 1l1l by Molmil](/molmil-images/mine/1l1l) | CRYSTAL STRUCTURE OF B-12 DEPENDENT (CLASS II) RIBONUCLEOTIDE REDUCTASE | Descriptor: | RIBONUCLEOSIDE TRIPHOSPHATE REDUCTASE | Authors: | Sintchak, M.D, Arjara, G, Kellogg, B.A, Stubbe, J, Drennan, C.L. | Deposit date: | 2002-02-18 | Release date: | 2002-04-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The crystal structure of class II ribonucleotide reductase reveals how an allosterically regulated monomer mimics a dimer. Nat.Struct.Biol., 9, 2002
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1A8F
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![BU of 1a8f by Molmil](/molmil-images/mine/1a8f) | HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE | Descriptor: | CARBONATE ION, FE (III) ION, SERUM TRANSFERRIN | Authors: | Macgillivray, R.T.A, Moore, S.A, Chen, J, Anderson, B.F, Baker, H, Luo, Y, Bewley, M, Smith, C.A, Murphy, M.E.P, Wang, Y, Mason, A.B, Woodworth, R.C, Brayer, G.D, Baker, E.N. | Deposit date: | 1998-03-25 | Release date: | 1998-06-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Two high-resolution crystal structures of the recombinant N-lobe of human transferrin reveal a structural change implicated in iron release. Biochemistry, 37, 1998
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2NZA
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![BU of 2nza by Molmil](/molmil-images/mine/2nza) | |
152L
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![BU of 152l by Molmil](/molmil-images/mine/152l) | |
5RSA
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![BU of 5rsa by Molmil](/molmil-images/mine/5rsa) | |
4QYH
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![BU of 4qyh by Molmil](/molmil-images/mine/4qyh) | CHK1 kinase domain in complex with diazacarbazole GNE-783 | Descriptor: | 3-[4-(4-methylpiperazin-1-yl)phenyl]-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile, Serine/threonine-protein kinase Chk1 | Authors: | Wiesmann, C, Wu, P. | Deposit date: | 2014-07-24 | Release date: | 2014-12-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery of the 1,7-diazacarbazole class of inhibitors of checkpoint kinase 1. Bioorg.Med.Chem.Lett., 24, 2014
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1Q3O
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![BU of 1q3o by Molmil](/molmil-images/mine/1q3o) | Crystal structure of the Shank PDZ-ligand complex reveals a class I PDZ interaction and a novel PDZ-PDZ dimerization | Descriptor: | BROMIDE ION, Shank1 | Authors: | Im, Y.J, Lee, J.H, Park, S.H, Park, S.J, Rho, S.-H, Kang, G.B, Kim, E, Eom, S.H. | Deposit date: | 2003-07-31 | Release date: | 2004-01-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the Shank PDZ-ligand complex reveals a class I PDZ interaction and a novel PDZ-PDZ dimerization J.Biol.Chem., 278, 2003
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1A5D
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![BU of 1a5d by Molmil](/molmil-images/mine/1a5d) | GAMMAE CRYSTALLIN FROM RAT LENS | Descriptor: | GAMMAE CRYSTALLIN | Authors: | Norledge, B.V, Hay, R, Bateman, O.A, Slingsby, C, Driessen, H.P.C. | Deposit date: | 1998-02-12 | Release date: | 1998-05-27 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Towards a molecular understanding of phase separation in the lens: a comparison of the X-ray structures of two high Tc gamma-crystallins, gammaE and gammaF, with two low Tc gamma-crystallins, gammaB and gammaD. Exp.Eye Res., 65, 1997
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1CPB
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1YEX
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![BU of 1yex by Molmil](/molmil-images/mine/1yex) | Structural and biochemical analysis of the link between enzymatic activity and oligomerization in AhpC, a bacterial peroxiredoxin. | Descriptor: | Alkyl hydroperoxide reductase subunit C, SULFATE ION | Authors: | Parsonage, D, Youngblood, D.S, Sarma, G.N, Wood, Z.A, Karplus, P.A, Poole, L.B. | Deposit date: | 2004-12-28 | Release date: | 2005-08-16 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Analysis of the Link between Enzymatic Activity and Oligomeric State in AhpC, a Bacterial Peroxiredoxin. Biochemistry, 44, 2005
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1PCA
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![BU of 1pca by Molmil](/molmil-images/mine/1pca) | THREE DIMENSIONAL STRUCTURE OF PORCINE PANCREATIC PROCARBOXYPEPTIDASE A. A COMPARISON OF THE A AND B ZYMOGENS AND THEIR DETERMINANTS FOR INHIBITION AND ACTIVATION | Descriptor: | CITRIC ACID, PROCARBOXYPEPTIDASE A PCPA, VALINE, ... | Authors: | Guasch, A, Coll, M, Aviles, F.X, Huber, R. | Deposit date: | 1991-10-28 | Release date: | 1993-10-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Three-dimensional structure of porcine pancreatic procarboxypeptidase A. A comparison of the A and B zymogens and their determinants for inhibition and activation. J.Mol.Biol., 224, 1992
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1YEP
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![BU of 1yep by Molmil](/molmil-images/mine/1yep) | Structural and biochemical analysis of the link between enzymatic activity and olgomerization in AhpC, a bacterial peroxiredoxin. | Descriptor: | Alkyl hydroperoxide reductase subunit C, SULFATE ION | Authors: | Parsonage, D, Youngblood, D.S, Sarma, G.N, Wood, Z.A, Karplus, P.A, Poole, L.B. | Deposit date: | 2004-12-28 | Release date: | 2005-08-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Analysis of the Link between Enzymatic Activity and Oligomeric State in AhpC, a Bacterial Peroxiredoxin. Biochemistry, 44, 2005
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1UN4
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![BU of 1un4 by Molmil](/molmil-images/mine/1un4) | |
3Q8H
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![BU of 3q8h by Molmil](/molmil-images/mine/3q8h) | Crystal structure of 2c-methyl-d-erythritol 2,4-cyclodiphosphate synthase from burkholderia pseudomallei in complex with cytidine derivative EBSI01028 | Descriptor: | 1,2-ETHANEDIOL, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 5'-deoxy-5'-[(imidazo[2,1-b][1,3]thiazol-5-ylcarbonyl)amino]cytidine, ... | Authors: | Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2011-01-06 | Release date: | 2011-01-19 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Cytidine derivatives as IspF inhibitors of Burkolderia pseudomallei. Bioorg.Med.Chem.Lett., 23, 2013
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2POG
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![BU of 2pog by Molmil](/molmil-images/mine/2pog) | Benzopyrans as Selective Estrogen Receptor b Agonists (SERBAs). Part 2: Structure Activity Relationship Studies on the Benzopyran Scaffold. | Descriptor: | (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL, Estrogen receptor | Authors: | Richardson, T.I, Norman, B.H, Lugar, C.W, Jones, S.A, Wang, Y, Durbin, J.D, Krishnan, V, Dodge, J.A. | Deposit date: | 2007-04-26 | Release date: | 2007-09-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 2: structure-activity relationship studies on the benzopyran scaffold. Bioorg.Med.Chem.Lett., 17, 2007
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2BCK
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![BU of 2bck by Molmil](/molmil-images/mine/2bck) | Crystal Structure of HLA-A*2402 Complexed with a telomerase peptide | Descriptor: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | Authors: | Rizkallah, P.J, Jakobsen, B.K, Cole, D.K, Gao, G.F. | Deposit date: | 2005-10-19 | Release date: | 2006-01-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of HLA-A*2402 complexed with a telomerase peptide. Eur.J.Immunol., 36, 2006
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5OTJ
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![BU of 5otj by Molmil](/molmil-images/mine/5otj) | Monomeric polcalcin (Phl p 7) in complex with two identical allergen-specific antibodies | Descriptor: | 1,2-ETHANEDIOL, 102.1F10 Fab heavy chain, 102.1F10 Fab light chain, ... | Authors: | Mitropoulou, A.N, Davies, A.M, Beavil, A.J, McDonnell, J.M, Sutton, B.J. | Deposit date: | 2017-08-22 | Release date: | 2018-09-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of a patient-derived antibody in complex with allergen reveals simultaneous conventional and superantigen-like recognition. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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