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2VR1
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BU of 2vr1 by Molmil
Crystal structure of Biotin carboxylase from E. coli in complex with ATP analog, ADPCF2P.
Descriptor: BIOTIN CARBOXYLASE, CHLORIDE ION, PHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Mochalkin, I, Waldrop, G.L.
Deposit date:2008-03-24
Release date:2008-09-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase.
Protein Sci., 17, 2008
6HXL
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BU of 6hxl by Molmil
Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH (space group P21)
Descriptor: 1,2-ETHANEDIOL, ATP-citrate synthase, CITRATE ANION, ...
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-10-17
Release date:2019-04-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXM
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BU of 6hxm by Molmil
Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH in space group C2221
Descriptor: ATP-citrate synthase, CITRATE ANION, COENZYME A
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-10-17
Release date:2019-04-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
3H78
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BU of 3h78 by Molmil
Crystal structure of Pseudomonas aeruginosa PqsD C112A mutant in complex with anthranilic acid
Descriptor: 2-AMINOBENZOIC ACID, PQS biosynthetic enzyme
Authors:Bera, A.K, Atanasova, V, Parsons, J.F.
Deposit date:2009-04-24
Release date:2009-09-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of PqsD, a Pseudomonas quinolone signal biosynthetic enzyme, in complex with anthranilate.
Biochemistry, 48, 2009
6HXK
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BU of 6hxk by Molmil
Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate
Descriptor: 1,2-ETHANEDIOL, ATP-citrate synthase, CITRATE ANION, ...
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-10-17
Release date:2019-04-10
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
5BY7
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BU of 5by7 by Molmil
AbyA1 - tetronic acid condensing enzyme
Descriptor: 3-oxoacyl-ACP synthase III
Authors:Byrne, M.J, Race, P.R.
Deposit date:2015-06-10
Release date:2016-06-29
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of AbyA1, a tetronic acid condensing enzyme from the Abyssomicin polyketide synthase.
To Be Published
5XUK
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BU of 5xuk by Molmil
Crystal structure of Helicobacter pylori holo-[acyl-carrier-protein] synthase (AcpS) in complex with coenzyme A
Descriptor: COENZYME A, Holo-[acyl-carrier-protein] synthase
Authors:Liao, Y.P, Wang, D.L, Yin, D.P, Zhang, Q.Y, Wang, Y.M, Wang, D.Q, Zhu, H.X, Chen, S.
Deposit date:2017-06-23
Release date:2018-06-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of acyl carrier protein synthases (AcpS) from three Gram-negative bacteria
To Be Published
3O04
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BU of 3o04 by Molmil
Crystal structure of the beta-keto-acyl carrier protein synthase II (lmo2201) from Listeria monocytogenes
Descriptor: beta-keto-acyl carrier protein synthase II
Authors:Anderson, S.M, Wawrzak, Z, Onopriyenko, O, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-07-19
Release date:2010-08-04
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the beta-keto-acyl carrier protein synthase II (lmo2201) from Listeria monocytogenes
To be Published
2ALM
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BU of 2alm by Molmil
Crystal structure analysis of a mutant beta-ketoacyl-[acyl carrier protein] synthase II from Streptococcus pneumoniae
Descriptor: 3-oxoacyl-(acyl-carrier-protein) synthase II, MAGNESIUM ION
Authors:Zhang, Y.M, Hurlbert, J, White, S.W, Rock, C.O.
Deposit date:2005-08-07
Release date:2005-08-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Roles of the active site water, histidine 303, and phenylalanine 396 in the catalytic mechanism of the elongation condensing enzyme of Streptococcus pneumoniae.
J.Biol.Chem., 281, 2006
5XU7
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BU of 5xu7 by Molmil
Crystal structure of Escherichia coli holo-[acyl-carrier-protein] synthase (AcpS)
Descriptor: CHLORIDE ION, GLYCEROL, Holo-[acyl-carrier-protein] synthase
Authors:Liao, Y.P, Wang, D.L, Yin, D.P, Zhang, Q.Y, Wang, Y.M, Wang, D.Q, Zhu, H.X, Chen, S.
Deposit date:2017-06-22
Release date:2018-06-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Crystal structures of acyl carrier protein synthases (AcpS) from three Gram-negative bacteria
To Be Published
5XUH
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BU of 5xuh by Molmil
Crystal structure of Escherichia coli holo-[acyl-carrier-protein] synthase (AcpS) D9A mutant in complex with CoA
Descriptor: CHLORIDE ION, COENZYME A, GLYCEROL, ...
Authors:Liao, Y.P, Wang, D.L, Yin, D.P, Zhang, Q.Y, Wang, Y.M, Wang, D.Q, Zhu, H.X, Chen, S.
Deposit date:2017-06-23
Release date:2018-06-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Crystal structures of acyl carrier protein synthases (AcpS) from three Gram-negative bacteria
To Be Published
4MZ0
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BU of 4mz0 by Molmil
Structure of a ketosynthase-acyltransferase di-domain from module CurL of the curacin A polyketide synthase
Descriptor: CALCIUM ION, CurL
Authors:Whicher, J.R, Smaga, S.S, Smith, J.L.
Deposit date:2013-09-28
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Cyanobacterial polyketide synthase docking domains: a tool for engineering natural product biosynthesis.
Chem.Biol., 20, 2013
3EJE
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BU of 3eje by Molmil
Crystal Structure of P450BioI in complex with octadec-9Z-enoic acid ligated Acyl Carrier Protein
Descriptor: Acyl carrier protein, Biotin biosynthesis cytochrome P450-like enzyme, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Cryle, M.J, Schlichting, I.
Deposit date:2008-09-18
Release date:2008-10-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3EJD
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BU of 3ejd by Molmil
Crystal Structure of P450BioI in complex with hexadec-9Z-enoic acid ligated Acyl Carrier Protein
Descriptor: Acyl carrier protein, Biotin biosynthesis cytochrome P450-like enzyme, CHLORIDE ION, ...
Authors:Cryle, M.J, Schlichting, I.
Deposit date:2008-09-18
Release date:2008-10-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3EJB
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BU of 3ejb by Molmil
Crystal Structure of P450BioI in complex with tetradecanoic acid ligated Acyl Carrier Protein
Descriptor: Acyl carrier protein, Biotin biosynthesis cytochrome P450-like enzyme, CHLORIDE ION, ...
Authors:Cryle, M.J, Schlichting, I.
Deposit date:2008-09-18
Release date:2008-10-07
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2CZU
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BU of 2czu by Molmil
lipocalin-type prostaglandin D synthase
Descriptor: Prostaglandin-H2 D-isomerase
Authors:Kumasaka, T, Irikura, D, Ago, H, Aritake, K, Yamamoto, M, Inoue, T, Miyano, M, Urade, Y, Hayaishi, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-17
Release date:2006-10-03
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of the catalytic mechanism operating in open-closed conformers of lipocalin type prostaglandin D synthase.
J.Biol.Chem., 284, 2009
3DAM
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BU of 3dam by Molmil
Crystal Structure of Allene oxide synthase
Descriptor: Cytochrome P450 74A2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Li, L, Wang, X.
Deposit date:2008-05-29
Release date:2008-09-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Modes of heme binding and substrate access for cytochrome P450 CYP74A revealed by crystal structures of allene oxide synthase.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2CZT
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BU of 2czt by Molmil
lipocalin-type prostaglandin D synthase
Descriptor: Prostaglandin-H2 D-isomerase
Authors:Kumasaka, T, Irikura, D, Ago, H, Aritake, K, Yamamoto, M, Inoue, T, Miyano, M, Urade, Y, Hayaishi, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-17
Release date:2006-10-03
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of the catalytic mechanism operating in open-closed conformers of lipocalin type prostaglandin D synthase.
J.Biol.Chem., 284, 2009
3DAN
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BU of 3dan by Molmil
Crystal Structure of Allene oxide synthase
Descriptor: Cytochrome P450 74A2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Li, L, Wang, X.
Deposit date:2008-05-29
Release date:2008-09-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Modes of heme binding and substrate access for cytochrome P450 CYP74A revealed by crystal structures of allene oxide synthase.
Proc.Natl.Acad.Sci.Usa, 105, 2008
4XOX
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BU of 4xox by Molmil
Structure of beta-ketoacyl-ACP synthase I (FabB) from Vibrio Cholerae
Descriptor: 3-oxoacyl-ACP synthase
Authors:Hou, J, Grabowski, M, Cymborowski, M, Zheng, H, Cooper, D.R, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2015-01-16
Release date:2015-01-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structure of beta-ketoacyl-ACP synthase I (FabB) from Vibrio Cholerae
to be published
7LIW
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BU of 7liw by Molmil
Local refinement of human ATP citrate lyase E599Q mutant ASH domain
Descriptor: (2S)-2-hydroxy-2-[2-oxo-2-(phosphonooxy)ethyl]butanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
Authors:Wei, X, Marmorstein, R.
Deposit date:2021-01-28
Release date:2021-05-19
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Nat.Struct.Mol.Biol., 28, 2021
2RCL
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BU of 2rcl by Molmil
Crystal Structure of Arabidopsis thaliana Allene Oxide Synthase (AOS, cytochrome P450 74A, CYP74A) Complexed with 12R,13S-Vernolic Acid at 2.4 A resolution
Descriptor: (9Z)-11-[(2R,3S)-3-pentyloxiran-2-yl]undec-9-enoic acid, Cytochrome P450 74A, GLYCEROL, ...
Authors:Lee, D.S, Nioche, P, Raman, C.S.
Deposit date:2007-09-20
Release date:2008-08-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Structural insights into the evolutionary paths of oxylipin biosynthetic enzymes.
Nature, 455, 2008
2JCA
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BU of 2jca by Molmil
Crystal structure of the streptomyces coelicolor holo- [Acyl-carrier-protein] Synthase (AcpS) at 2 A.
Descriptor: GLYCEROL, HOLO-[ACYL-CARRIER-PROTEIN] SYNTHASE, SODIUM ION, ...
Authors:Dall'Aglio, P, Arthur, C, Crump, M.P, Crosby, J, Hadfield, A.T.
Deposit date:2006-12-21
Release date:2007-01-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Analysis of Streptomyces Coelicolor Phosphopantetheinyl Transferase, Acps, Reveals the Basis for Relaxed Substrate Specificity.
Biochemistry, 50, 2011
2JBZ
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BU of 2jbz by Molmil
Crystal structure of the Streptomyces coelicolor holo-[Acyl-carrier-protein] Synthase (AcpS) in complex with coenzyme A at 1.6 A
Descriptor: COENZYME A, HOLO-[ACYL-CARRIER-PROTEIN] SYNTHASE, MAGNESIUM ION, ...
Authors:Dall'Aglio, P, Arthur, C, Law, C.K.E, Crump, M.P, Crosby, J, Hadfield, A.T.
Deposit date:2006-12-15
Release date:2007-01-23
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Analysis of Streptomyces Coelicolor Phosphopantetheinyl Transferase, Acps, Reveals the Basis for Relaxed Substrate Specificity.
Biochemistry, 50, 2011
4IMN
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BU of 4imn by Molmil
Crystal structure of wild type human Lipocalin PGDS bound with PEG MME 2000
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Lipocalin-type prostaglandin-D synthase
Authors:Lim, S.M, Chen, D, Teo, H, Roos, A, Nyman, T, Tresaugues, L, Pervushin, K, Nordlund, P.
Deposit date:2013-01-03
Release date:2013-03-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase.
J.Lipid Res., 54, 2013

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