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4U4T
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BU of 4u4t by Molmil
Structure of a nitrate/nitrite antiporter NarK in nitrate-bound inward-open state
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, NITRATE ION, Nitrate/nitrite transporter NarK, ...
Authors:Fukuda, M, Takeda, H, Kato, H.E, Doki, S, Ito, K, Maturana, A.D, Ishitani, R, Nureki, O.
Deposit date:2014-07-24
Release date:2015-07-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for dynamic mechanism of nitrate/nitrite antiport by NarK
Nat Commun, 6, 2015
7NUY
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BU of 7nuy by Molmil
New polymorhp of proteinase K obtained by free interface diffusion technique
Descriptor: Proteinase K, SULFATE ION
Authors:Gavira, J.A, Artusio, F, Castellvi, A, Pisano, R.
Deposit date:2021-03-15
Release date:2022-01-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Tuning Transport Phenomena in Agarose Gels for the Control of Protein Nucleation Density and Crystal Form
Crystals, 2021
3QWR
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BU of 3qwr by Molmil
Crystal structure of IL-23 in complex with an adnectin
Descriptor: ADNECTIN, Interleukin-12 subunit beta, Interleukin-23 subunit alpha, ...
Authors:Wei, A, Sheriff, S.
Deposit date:2011-02-28
Release date:2012-02-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structures of adnectin/protein complexes reveal an expanded binding footprint.
Structure, 20, 2012
5OOO
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BU of 5ooo by Molmil
Structure of the Rift Valley fever virus NSs protein core domain
Descriptor: Non-structural protein NS-S
Authors:Barski, M.S, Potter, J.A, Schwarz-Linek, U.
Deposit date:2017-08-08
Release date:2017-08-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Rift Valley fever phlebovirus NSs protein core domain structure suggests molecular basis for nuclear filaments.
Elife, 6, 2017
4UEL
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BU of 4uel by Molmil
UCH-L5 in complex with ubiquitin-propargyl bound to the RPN13 DEUBAD domain
Descriptor: POLYUBIQUITIN-B, PROTEASOMAL UBIQUITIN RECEPTOR ADRM1, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5
Authors:Sahtoe, D.D, Van Dijk, W.J, El Oualid, F, Ekkebus, R, Ovaa, H, Sixma, T.K.
Deposit date:2014-12-18
Release date:2015-03-04
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of Uch-L5 Activation and Inhibition by Deubad Domains in Rpn13 and Ino80G.
Mol.Cell, 57, 2015
4UIQ
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BU of 4uiq by Molmil
Isolated globin domain of the Bordetella pertussis globin-coupled sensor with a heme at the dimer interface
Descriptor: GLOBIN-COUPLED SENSOR WITH DIGUANYLATE CYCLASE ACTIVITY, GLYCEROL, IMIDAZOLE, ...
Authors:Germani, F, Donne, J, De Schutter, A, Pesce, A, Berghmans, H, Van Hauwaert, M.-L, Moens, L, Van Doorslaer, S, Bolognesi, M, Nardini, M, Dewilde, S.
Deposit date:2015-03-31
Release date:2016-04-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Identification of a Putative Allosteric Site in the Sensor Domain of Bordetella Pertussis Globin- Coupled Sensor for the Control of Biofilm Formation
To be Published
4UVM
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BU of 4uvm by Molmil
In meso crystal structure of the POT family transporter PepTSo
Descriptor: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, GLUTATHIONE UPTAKE TRANSPORTER
Authors:Lyons, J.A, Solcan, N, Caffrey, M, Newstead, S.
Deposit date:2014-08-07
Release date:2015-02-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Gating Topology of the Proton-Coupled Oligopeptide Symporters.
Structure, 23, 2015
5JLH
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BU of 5jlh by Molmil
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 2, ...
Authors:von der Ecken, J, Heissler, S.M, Pathan-Chhatbar, S, Manstein, D.J, Raunser, S.
Deposit date:2016-04-27
Release date:2016-06-15
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution.
Nature, 534, 2016
5J39
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BU of 5j39 by Molmil
Crystal Structure of the extended TUDOR domain from TDRD2
Descriptor: CACODYLATE ION, Tudor and KH domain-containing protein, UNKNOWN ATOM OR ION
Authors:Zhang, H, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2016-03-30
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for arginine methylation-independent recognition of PIWIL1 by TDRD2.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4V0S
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BU of 4v0s by Molmil
Crystal structure of Mycobacterium tuberculosis Type II Dehydroquinase D88N mutant inhibited by a 3-dehydroquinic acid derivative
Descriptor: (1R,2S,4S,5R)-2-(2,3,4,5,6-pentafluorophenyl)methyl-1,4,5-trihydroxy-3-oxocyclohexane-1-carboxylic acid, 3,4-DIHYDROXY-2-[(2,3,4,5,6-PENTAFLUOROPHENYL)METHYL]BENZOIC ACID, 3-DEHYDROQUINATE DEHYDRATASE, ...
Authors:Otero, J.M, Llamas-Saiz, A.L, Santiago, C, Lamb, H, Hawkins, A.R, Maneiro, M, Peon, A, Gonzalez-Bello, C, van Raaij, M.J.
Deposit date:2014-09-18
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Investigation of the Dehydratation Mechanism Catalyzed by the Type II Dehydroquinase
To be Published
6RPT
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BU of 6rpt by Molmil
Structure of tick complement inhibitor CirpT1 complexed with macroglobubulin domain 4 of human complement C5
Descriptor: Complement C5, GLYCEROL, Putative 8.9 kDa family member
Authors:Reichhardt, M.P, Lea, S.M, Johnson, S.
Deposit date:2019-05-14
Release date:2020-01-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:An inhibitor of complement C5 provides structural insights into activation.
Proc.Natl.Acad.Sci.USA, 117, 2020
5VMS
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BU of 5vms by Molmil
CryoEM structure of Xenopus KCNQ1 channel
Descriptor: CALCIUM ION, Calmodulin, Potassium voltage-gated channel subfamily KQT member 1
Authors:Mackinnon, R, Sun, J.
Deposit date:2017-04-28
Release date:2017-06-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM Structure of a KCNQ1/CaM Complex Reveals Insights into Congenital Long QT Syndrome.
Cell, 169, 2017
8THJ
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BU of 8thj by Molmil
Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Haemophilus influenzae (antiparallel dimer)
Descriptor: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, PHOSPHATIDYLETHANOLAMINE, SODIUM ION, ...
Authors:Davies, J.S, Currie, M.C, Dobson, R.C.J, North, R.A.
Deposit date:2023-07-16
Release date:2023-11-22
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter.
Elife, 12, 2024
8THI
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BU of 8thi by Molmil
Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Haemophilus influenzae (parallel dimer)
Descriptor: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, SODIUM ION, Sialic acid TRAP transporter permease protein SiaT
Authors:Davies, J.S, Currie, M.C, Dobson, R.C.J, North, R.A.
Deposit date:2023-07-16
Release date:2023-11-22
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter.
Elife, 12, 2024
7P2B
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BU of 7p2b by Molmil
Crystal structure of human gelsolin amyloid mutant A551P
Descriptor: CHLORIDE ION, GLYCEROL, Gelsolin, ...
Authors:Bollati, M, de Rosa, M.
Deposit date:2021-07-05
Release date:2022-05-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:A novel hotspot of gelsolin instability triggers an alternative mechanism of amyloid aggregation.
Comput Struct Biotechnol J, 19, 2021
6LNI
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BU of 6lni by Molmil
Cryo-EM structure of amyloid fibril formed by full-length human prion protein
Descriptor: Major prion protein
Authors:Wang, L.Q, Zhao, K, Yuan, H.Y, Wang, Q, Guan, Z.Y, Tao, J, Li, X.N, Hao, M.M, Chen, J, Zhang, D.L, Zhu, H.L, Yin, P, Liu, C, Liang, Y.
Deposit date:2019-12-30
Release date:2020-06-10
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (2.702 Å)
Cite:Cryo-EM structure of an amyloid fibril formed by full-length human prion protein.
Nat.Struct.Mol.Biol., 27, 2020
2ERJ
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BU of 2erj by Molmil
Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Debler, E.W, Stauber, D.J, Wilson, I.A.
Deposit date:2005-10-25
Release date:2006-02-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3SUI
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BU of 3sui by Molmil
Crystal structure of ca2+-calmodulin in complex with a trpv1 c-terminal peptide
Descriptor: CALCIUM ION, Calmodulin, SULFATE ION, ...
Authors:Lau, S.-Y, Gaudet, R.
Deposit date:2011-07-11
Release date:2012-09-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Distinct properties of Ca2+-calmodulin binding to N- and C-terminal regulatory regions of the TRPV1 channel.
J.Gen.Physiol., 140, 2012
2FUC
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BU of 2fuc by Molmil
Human alpha-Phosphomannomutase 1 with Mg2+ cofactor bound
Descriptor: MAGNESIUM ION, Phosphomannomutase 1
Authors:Silvaggi, N.R, Zhang, C, Lu, Z, Dunaway-Mariano, D, Allen, K.N.
Deposit date:2006-01-26
Release date:2006-03-21
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The X-ray crystal structures of human alpha-phosphomannomutase 1 reveal the structural basis of congenital disorder of glycosylation type 1a.
J.Biol.Chem., 281, 2006
5YZP
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BU of 5yzp by Molmil
Crystal structure of p204 HINa domain
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Ifi204
Authors:Jin, T.
Deposit date:2017-12-15
Release date:2018-12-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.581 Å)
Cite:Structural mechanism of DNA recognition by the p204 HIN domain.
Nucleic Acids Res., 2021
8P94
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BU of 8p94 by Molmil
Cryo-EM structure of cortactin stabilized Arp2/3-complex nucleated actin branches
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Liu, T, Moores, C.A.
Deposit date:2023-06-05
Release date:2024-01-03
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cortactin stabilizes actin branches by bridging activated Arp2/3 to its nucleated actin filament.
Nat.Struct.Mol.Biol., 31, 2024
5ZKK
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BU of 5zkk by Molmil
Crystal structure of Phosphoserine phosphatase from Entamoeba histolytica
Descriptor: BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Kumari, P, Gourinath, S.
Deposit date:2018-03-24
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and functional characterisation of phosphoserine phosphatase, that plays critical role in the oxidative stress response in the parasite Entamoeba histolytica.
J.Struct.Biol., 206, 2019
2FUE
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BU of 2fue by Molmil
Human alpha-Phosphomannomutase 1 with D-mannose 1-phosphate and Mg2+ cofactor bound
Descriptor: 1-O-phosphono-alpha-D-mannopyranose, MAGNESIUM ION, Phosphomannomutase 1
Authors:Silvaggi, N.R, Zhang, C, Lu, Z, Dunaway-Mariano, D, Allen, K.N.
Deposit date:2006-01-26
Release date:2006-03-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The X-ray crystal structures of human alpha-phosphomannomutase 1 reveal the structural basis of congenital disorder of glycosylation type 1a.
J.Biol.Chem., 281, 2006
5WBX
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BU of 5wbx by Molmil
Structural insights into the potency of SK/IK channel positive modulators
Descriptor: (3Z)-6-bromo-3-(hydroxyimino)-5-methyl-1,3-dihydro-2H-indol-2-one, CALCIUM ION, Calmodulin-1, ...
Authors:Nam, Y.W, Zhang, M.
Deposit date:2017-06-29
Release date:2017-12-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into the potency of SK channel positive modulators.
Sci Rep, 7, 2017
5WC5
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BU of 5wc5 by Molmil
Structural insights into the potency of SK/IK channel positive modulators
Descriptor: 7-fluoro-3-(hydroxyamino)-2H-indol-2-one, CALCIUM ION, Calmodulin-1, ...
Authors:Nam, Y.W, Zhang, M.
Deposit date:2017-06-29
Release date:2017-12-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the potency of SK channel positive modulators.
Sci Rep, 7, 2017

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