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4YWS	Thermostable enolase from Chloroflexus aurantiacus Descriptor: Enolase, MAGNESIUM ION Authors: Zadvornyy, O.A, Peters, J.W. Deposit date: 2015-03-20 Release date: 2015-07-01 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Biochemical and Structural Characterization of Enolase from Chloroflexus aurantiacus: Evidence for a Thermophilic Origin. Front Bioeng Biotechnol, 3, 2015
4ENL	CRYSTAL STRUCTURE OF HOLOENZYME REFINED AT 1.9 ANGSTROMS RESOLUTION: TRIGONAL-BIPYRAMIDAL GEOMETRY OF THE CATION BINDING SITE Descriptor: ENOLASE, SULFATE ION, ZINC ION Authors: Lebioda, L, Stec, B. Deposit date: 1990-11-13 Release date: 1992-04-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal Structure of Holoenzyme Refined at 1.9 Angstroms Resolution: Trigonal-Bipyramidal Geometry of the Cation Binding Site J.Am.Chem.Soc., 111, 1989
1TE6	Crystal Structure of Human Neuron Specific Enolase at 1.8 angstrom Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Gamma enolase, ... Authors: Chai, G, Brewer, J, Lovelace, L, Aoki, T, Minor, W, Lebioda, L. Deposit date: 2004-05-24 Release date: 2004-09-21 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Expression, Purification and the 1.8 A Resolution Crystal Structure of Human Neuron Specific Enolase J.Mol.Biol., 341, 2004
5J04	Crystal structure of Enolase from Synechococcus elongatus, complex with phosphoenolpyruvate Descriptor: ACETATE ION, CALCIUM ION, Enolase, ... Authors: Gonzalez, J.M. Deposit date: 2016-03-26 Release date: 2016-04-20 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The structure of Synechococcus elongatus enolase reveals key aspects of phosphoenolpyruvate binding Acta Crystallogr.,Sect.F, F78, 2022
5TD9	Structure of Human Enolase 2 Descriptor: CHLORIDE ION, Gamma-enolase, MAGNESIUM ION Authors: Leonard, P.G, Muller, F.L. Deposit date: 2016-09-19 Release date: 2017-09-27 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.318 Å) Cite: Pomhex, a cell-permeable Enolase inhibitor for Collateral Lethality targeting of ENO1-deleted Glioblastoma To Be Published
5ENL	INHIBITION OF ENOLASE: THE CRYSTAL STRUCTURES OF ENOLASE-CA2+-PHOSPHOGLYCERATE AND ENOLASE-ZN2+-PHOSPHOGLYCOLATE COMPLEXES AT 2.2-ANGSTROMS RESOLUTION Descriptor: 2-PHOSPHOGLYCERIC ACID, CALCIUM ION, ENOLASE Authors: Lebioda, L, Stec, B. Deposit date: 1990-11-13 Release date: 1992-04-15 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Inhibition of enolase: the crystal structures of enolase-Ca2(+)- 2-phosphoglycerate and enolase-Zn2(+)-phosphoglycolate complexes at 2.2-A resolution. Biochemistry, 30, 1991
4ZCW	Structure of Human Enolase 2 in complex with SF2312 Descriptor: Gamma-enolase, MAGNESIUM ION, [(3S,5S)-1,5-dihydroxy-2-oxopyrrolidin-3-yl]phosphonic acid Authors: Leonard, P.G, Maxwell, D, Czako, B, Muller, F.L. Deposit date: 2015-04-16 Release date: 2016-07-20 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.992 Å) Cite: SF2312 is a natural phosphonate inhibitor of enolase. Nat.Chem.Biol., 12, 2016
1W6T	Crystal Structure Of Octameric Enolase From Streptococcus pneumoniae Descriptor: ENOLASE, MAGNESIUM ION, NONAETHYLENE GLYCOL Authors: Ehinger, S, Schubert, W.-D, Bergmann, S, Hammerschmidt, S, Heinz, D.W. Deposit date: 2004-08-24 Release date: 2005-08-22 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Plasmin(Ogen)-Binding Alpha-Enolase from Streptococcus Pneumoniae: Crystal Structure and Evaluation of Plasmin(Ogen)-Binding Sites J.Mol.Biol., 343, 2004
5TIJ	Structure of Human Enolase 2 with ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonate (purified enantiomer) Descriptor: ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid, Gamma-enolase, MAGNESIUM ION Authors: Leonard, P.G, Muller, F.L. Deposit date: 2016-10-03 Release date: 2017-10-18 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.634 Å) Cite: Eradication of ENO1-deleted Glioblastoma through Collateral Lethality Biorxiv, 2019
3H8A	Crystal structure of E. coli enolase bound to its cognate RNase E recognition domain Descriptor: Enolase, MAGNESIUM ION, RNase E Authors: Nurmohamed, S, Luisi, B.F. Deposit date: 2009-04-29 Release date: 2010-04-14 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Molecular recognition between Escherichia coli enolase and ribonuclease E. Acta Crystallogr.,Sect.D, 66, 2010
6NPF	Structure of E.coli enolase in complex with an analog of the natural product SF-2312 metabolite. Descriptor: Enolase, GLYCEROL, L(+)-TARTARIC ACID, ... Authors: Erlandsen, H, Krucinska, J, Lombardo, M, Wright, D. Deposit date: 2019-01-17 Release date: 2019-11-27 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.57 Å) Cite: Functional and structural basis of E. coli enolase inhibition by SF2312: a mimic of the carbanion intermediate. Sci Rep, 9, 2019
6NB2	CRYSTAL STRUCTURE OF ENOLASE FROM LEGIONELLA PNEUMOPHILA BOUND TO 2-PHOSPHOGLYCERIC ACID AND MAGNESIUM Descriptor: 1,2-ETHANEDIOL, 2-PHOSPHOGLYCERIC ACID, Enolase, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-12-06 Release date: 2019-01-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.85 Å) Cite: CRYSTAL STRUCTURE OF ENOLASE FROM LEGIONELLA PNEUMOPHILA BOUND TO 2-PHOSPHOGLYCERIC ACID AND MAGNESIUM To Be Published
7RHV	Aspergillus fumigatus Enolase Descriptor: Enolase, MAGNESIUM ION Authors: Nguyen, S, Bruning, J.B. Deposit date: 2021-07-19 Release date: 2022-03-16 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2 Å) Cite: A structural model of the human plasminogen and Aspergillus fumigatus enolase complex. Proteins, 90, 2022
7RI0	Aspergillus fumigatus Enolase Bound to Phosphoenolpyruvate and 2-Phosphoglycerate Descriptor: 2-PHOSPHOGLYCERIC ACID, Enolase, MAGNESIUM ION, ... Authors: Nguyen, S, Bruning, J.B. Deposit date: 2021-07-19 Release date: 2022-03-16 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: A structural model of the human plasminogen and Aspergillus fumigatus enolase complex. Proteins, 90, 2022
7RHW	Aspergillus fumigatus Enolase Bound to 2-Phosphoglycerate Descriptor: 2-PHOSPHOGLYCERIC ACID, Enolase, MAGNESIUM ION Authors: Nguyen, S, Bruning, J.B. Deposit date: 2021-07-19 Release date: 2022-03-16 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.9 Å) Cite: A structural model of the human plasminogen and Aspergillus fumigatus enolase complex. Proteins, 90, 2022
6O4N	Crystal Structure of Enolase from Chlamydia trachomatis Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2019-02-28 Release date: 2019-03-13 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal Structure of Enolase from Chlamydia trachomatis to be published
3UJE	Asymmetric complex of human neuron specific enolase-3-PGA/PEP Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-PHOSPHOGLYCERIC ACID, Gamma-enolase, ... Authors: Qin, J, Chai, G, Brewer, J, Lovelace, L, Lebioda, L. Deposit date: 2011-11-07 Release date: 2012-08-22 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity. J.Inorg.Biochem., 111, 2012
3UCC	Asymmetric complex of human neuron specific enolase-1-PGA/PEP Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-PHOSPHOGLYCERIC ACID, Gamma-enolase, ... Authors: Qin, J, Chai, G, Brewer, J, Lovelace, L, Lebioda, L. Deposit date: 2011-10-26 Release date: 2012-08-22 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity. J.Inorg.Biochem., 111, 2012
3UJF	Asymmetric complex of human neuron specific enolase-4-PGA/PEP Descriptor: 2-PHOSPHOGLYCERIC ACID, Gamma-enolase, MAGNESIUM ION, ... Authors: Qin, J, Chai, G, Brewer, J, Lovelace, L, Lebioda, L. Deposit date: 2011-11-07 Release date: 2012-08-22 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity. J.Inorg.Biochem., 111, 2012
3UJR	Asymmetric complex of human neuron specific enolase-5-PGA/PEP Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-PHOSPHOGLYCERIC ACID, Gamma-enolase, ... Authors: Qin, J, Chai, G, Brewer, J, Lovelace, L, Lebioda, L. Deposit date: 2011-11-08 Release date: 2012-08-22 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity. J.Inorg.Biochem., 111, 2012
1EBG	CHELATION OF SER 39 TO MG2+ LATCHES A GATE AT THE ACTIVE SITE OF ENOLASE: STRUCTURE OF THE BIS(MG2+) COMPLEX OF YEAST ENOLASE AND THE INTERMEDIATE ANALOG PHOSPHONOACETOHYDROXAMATE AT 2.1 ANGSTROMS RESOLUTION Descriptor: ENOLASE, MAGNESIUM ION, PHOSPHONOACETOHYDROXAMIC ACID Authors: Wedekind, J.E, Reed, G.H, Rayment, I. Deposit date: 1994-04-27 Release date: 1995-04-27 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Chelation of serine 39 to Mg2+ latches a gate at the active site of enolase: structure of the bis(Mg2+) complex of yeast enolase and the intermediate analog phosphonoacetohydroxamate at 2.1-A resolution. Biochemistry, 33, 1994
1ELS	CATALYTIC METAL ION BINDING IN ENOLASE: THE CRYSTAL STRUCTURE OF ENOLASE-MN2+-PHOSPHONOACETOHYDROXAMATE COMPLEX AT 2.4 ANGSTROMS RESOLUTION Descriptor: ENOLASE, MANGANESE (II) ION, PHOSPHONOACETOHYDROXAMIC ACID Authors: Zhang, E, Hatada, M, Brewer, J.M, Lebioda, L. Deposit date: 1994-04-05 Release date: 1994-07-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Catalytic metal ion binding in enolase: the crystal structure of an enolase-Mn2+-phosphonoacetohydroxamate complex at 2.4-A resolution. Biochemistry, 33, 1994
1E9I	Enolase from E.coli Descriptor: ENOLASE, MAGNESIUM ION, SULFATE ION Authors: Kuhnel, K, Carpousis, A.J, Luisi, B. Deposit date: 2000-10-17 Release date: 2001-03-15 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.48 Å) Cite: Crystal Structure of the Escherichia Coli RNA Degradosome Component Enolase J.Mol.Biol., 313, 2001
7UGH	Crystal Structure of enolase family protein from Naegleria fowleri with bound 2-phosphoglyceric acid Descriptor: 1,2-ETHANEDIOL, 2-PHOSPHOGLYCERIC ACID, ACETATE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2022-03-24 Release date: 2022-04-13 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal Structure of enolase family protein from Naegleria fowleri with bound 2-phosphoglyceric acid to be published
8UEL	Crystal structure of enolase from Litopenaeus vannamei Descriptor: Enolase, MAGNESIUM ION, PHOSPHOENOLPYRUVATE, ... Authors: Chang, X, Zhao, G. Deposit date: 2023-10-01 Release date: 2023-12-13 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Characterization and Structural Analyses of Enolase from Shrimp ( Litopenaeus vannamei ). J.Agric.Food Chem., 71, 2023

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