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1E3B
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CYCLOPHILIN 3 FROM C.ELEGANS COMPLEXED WITH AUP(ET)3
Descriptor: CYCLOPHILIN 3, GOLD ION, TRIETHYLPHOSPHANE
Authors:Zou, J, Taylor, P, Dornan, J, Robinson, S.P, Walkinshaw, M.D, Sadler, P.J.
Deposit date:2000-06-08
Release date:2000-10-22
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:First Crystal Structure of a Medicinally Relevant Gold Protein Complex:Unexpected Binding of [Au(Pet (3))](+) to Histidine
Angew.Chem.Int.Ed.Engl., 39, 2000
1E8K
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Cyclophilin 3 Complexed With Dipeptide Ala-Pro
Descriptor: ALANINE, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 3, PROLINE
Authors:Wu, S.Y, Dornan, J, Kontopidis, G, Taylor, P, Walkinshaw, M.D.
Deposit date:2000-09-25
Release date:2001-09-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The First Direct Determination of a Ligand Binding Constant in Protein Crystals
Angew.Chem.Int.Ed.Engl., 40, 2001
1FGL
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Cyclophilin A complexed with a fragment of HIV-1 GAG protein
Descriptor: CYCLOPHILIN A, HIV-1 GAG PROTEIN
Authors:Zhao, Y, Chen, Y, Schutkowski, M, Fischer, G, Ke, H.
Deposit date:1996-11-18
Release date:1997-04-01
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Cyclophilin A complexed with a fragment of HIV-1 gag protein: insights into HIV-1 infectious activity.
Structure, 5, 1997
1H0P
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Cyclophilin_5 from C. elegans
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 5
Authors:Picken, N.C, Eschenlauer, S, Taylor, P, Page, A.P, Walkinshaw, M.D.
Deposit date:2002-06-26
Release date:2002-09-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural and Biological Characterisation of the Gut-Associated Cyclophilin B Isoforms from Caenorhabditis Elegans
J.Mol.Biol., 322, 2002
1IHG
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Bovine Cyclophilin 40, monoclinic form
Descriptor: Cyclophilin 40, GLYCEROL
Authors:Taylor, P, Dornan, J, Carrello, A, Minchin, R.F, Ratajczak, T, Walkinshaw, M.D.
Deposit date:2001-04-19
Release date:2001-05-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Two structures of cyclophilin 40: folding and fidelity in the TPR domains.
Structure, 9, 2001
1IIP
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Bovine Cyclophilin 40, Tetragonal Form
Descriptor: Cyclophilin 40, GLYCEROL
Authors:Taylor, P, Dornan, J, Carrello, A, Minchin, R.F, Ratajczak, T, Walkinshaw, M.D.
Deposit date:2001-04-24
Release date:2001-05-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Two structures of cyclophilin 40: folding and fidelity in the TPR domains.
Structure, 9, 2001
1IST
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Crystal structure of yeast cyclophilin A, CPR1
Descriptor: Cyclophilin A
Authors:Konno, M, Kashima, A, Yoshikawa-Fujioka, S.
Deposit date:2001-12-25
Release date:2003-11-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Turns are Essential in the Folding of the Globular Beta-Barrel Structure of Yeast Cyclophilin A, CPR1
To be Published
1J2A
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Structure of E. coli cyclophilin B K163T mutant
Descriptor: cyclophilin B
Authors:Konno, M, Sano, Y, Okudaira, K, Kawaguchi, Y, Yamagishi-Ohmori, Y, Fushinobu, S, Matsuzawa, H.
Deposit date:2002-12-26
Release date:2004-02-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Escherichia coli cyclophilin B binds a highly distorted form of trans-prolyl peptide isomer
Eur.J.Biochem., 271, 2004
1LOP
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CYCLOPHILIN A COMPLEXED WITH SUCCINYL-ALA-PRO-ALA-P-NITROANILIDE
Descriptor: CYCLOPHILIN A, SUCCINYL-ALA-PRO-ALA-P-NITROANILIDE
Authors:Konno, M.
Deposit date:1996-06-17
Release date:1996-12-23
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The substrate-binding site in Escherichia coli cyclophilin A preferably recognizes a cis-proline isomer or a highly distorted form of the trans isomer.
J.Mol.Biol., 256, 1996
1M63
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Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes
Descriptor: CALCINEURIN B SUBUNIT ISOFORM 1, CALCIUM ION, CYCLOSPORIN A, ...
Authors:Huai, Q, Kim, H.-Y, Liu, Y, Zhao, Y, Mondragon, A, Liu, J.O, Ke, H.
Deposit date:2002-07-12
Release date:2002-09-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Calcineurin-Cyclophilin-Cyclosporin Shows Common But Distinct Recognition of Immunophilin-Drug Complexes
Proc.Natl.Acad.Sci.USA, 99, 2002
1M9C
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X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) M-type Complex.
Descriptor: Cyclophilin A, HIV-1 Capsid
Authors:Howard, B.R, Vajdos, F.F, Li, S, Sundquist, W.I, Hill, C.P.
Deposit date:2002-07-28
Release date:2003-05-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the catalytic mechanism of cyclophilin A
Nat.Struct.Biol., 10, 2003
1M9D
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X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) O-type chimera Complex.
Descriptor: Cyclophilin A, HIV-1 Capsid
Authors:Howard, B.R, Vajdos, F.F, Li, S, Sundquist, W.I, Hill, C.P.
Deposit date:2002-07-28
Release date:2003-05-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into the catalytic mechanism of cyclophilin A
Nat.Struct.Biol., 10, 2003
1M9E
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X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) M-type H87A Complex.
Descriptor: Cyclophilin A, HIV-1 Capsid
Authors:Howard, B.R, Vajdos, F.F, Li, S, Sundquist, W.I, Hill, C.P.
Deposit date:2002-07-28
Release date:2003-05-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural insights into the catalytic mechanism of cyclophilin A
Nat.Struct.Biol., 10, 2003
1M9F
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X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) M-type H87A,A88M Complex.
Descriptor: Cyclophilin A, HIV-1 Capsid
Authors:Howard, B.R, Vajdos, F.F, Li, S, Sundquist, W.I, Hill, C.P.
Deposit date:2002-07-28
Release date:2003-05-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structural insights into the catalytic mechanism of cyclophilin A
Nat.Struct.Biol., 10, 2003
1M9X
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X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) M-type H87A,A88M,G89A Complex.
Descriptor: Cyclophilin A, HIV-1 Capsid
Authors:Howard, B.R, Vajdos, F.F, Li, S, Sundquist, W.I, Hill, C.P.
Deposit date:2002-07-30
Release date:2003-05-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into the catalytic mechanism of cyclophilin A
Nat.Struct.Biol., 10, 2003
1M9Y
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X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) M-type H87A,G89A Complex.
Descriptor: Cyclophilin A, HIV-1 Capsid
Authors:Howard, B.R, Vajdos, F.F, Li, S, Sundquist, W.I, Hill, C.P.
Deposit date:2002-07-30
Release date:2003-05-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into the catalytic mechanism of cyclophilin A
Nat.Struct.Biol., 10, 2003
1MF8
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Crystal Structure of human calcineurin complexed with cyclosporin A and human cyclophilin
Descriptor: CALCINEURIN B SUBUNIT ISOFORM 1, CALCIUM ION, CALMODULIN-DEPENDENT CALCINEURIN A SUBUNIT, ...
Authors:Jin, L, Harrison, S.C.
Deposit date:2002-08-09
Release date:2002-10-16
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of Human Calcineurin Complexed with Cyclosporin a and Human Cyclophilin
Proc.Natl.Acad.Sci.USA, 99, 2002
1MIK
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THE ROLE OF WATER MOLECULES IN THE STRUCTURE-BASED DESIGN OF (5-HYDROXYNORVALINE)-2-CYCLOSPORIN: SYNTHESIS, BIOLOGICAL ACTIVITY, AND CRYSTALLOGRAPHIC ANALYSIS WITH CYCLOPHILIN A
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Mikol, V.
Deposit date:1995-09-20
Release date:1996-03-08
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:The Role of Water Molecules in the Structure-Based Design of (5-Hydroxynorvaline)-2-Cyclosporin: Synthesis, Biological Activity, and Crystallographic Analysis with Cyclophilin A.
J.Med.Chem., 38, 1995
1MZW
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Crystal structure of a U4/U6 snRNP complex between human spliceosomal cyclophilin H and a U4/U6-60K peptide
Descriptor: U-snRNP-associated cyclophilin, U4/U6 snrnp 60kDa protein
Authors:Reidt, U, Wahl, M.C, Horowitz, D.S, Luehrmann, R, Ficner, R.
Deposit date:2002-10-10
Release date:2003-08-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a complex between human spliceosomal cyclophilin H and a U4/U6 snRNP-60K peptide
J.Mol.Biol., 331, 2003
1NMK
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The Sanglifehrin-Cyclophilin Interaction: Degradation Work, Synthetic Macrocyclic Analogues, X-ray Crystal Structure and Binding Data
Descriptor: (13E,15E)-(3S,6S,9R,10R,11S,12S,18S,21S)-10,12-DIHYDROXY-3-(3-HYDROXYBEN-ZYL)-18-((E)-3-HYDROXY-1-METHYLPROPENYL)-6-ISOPROPYL-11-METHYL-9-(3-OXO-BUTYL)-19-OXA-1,4,7,25-TETRAAZA-BICYCLO[19.3.1]PENTACOSA-13,15-DIENE-2,5,8,20-TETRAONE, Peptidyl-prolyl cis-trans isomerase A
Authors:Kallen, J, Sedrani, R, Wagner, J.
Deposit date:2003-01-10
Release date:2003-04-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Sanglifehrin-Cyclophilin Interaction: Degradation Work, Synthetic Macrocyclic Analogues, X-ray Crystal Structure and Binding Data
J.Am.Chem.Soc., 125, 2003
1OCA
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HUMAN CYCLOPHILIN A, UNLIGATED, NMR, 20 STRUCTURES
Descriptor: CYCLOPHILIN A
Authors:Ottiger, M, Zerbe, O, Guntert, P, Wuthrich, K.
Deposit date:1997-07-07
Release date:1997-11-19
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The NMR solution conformation of unligated human cyclophilin A.
J.Mol.Biol., 272, 1997
1QNG
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Plasmodium falciparum Cyclophilin complexed with Cyclosporin A
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE
Authors:Peterson, M.R, Hall, D.R, Hunter, W.N.
Deposit date:1999-10-14
Release date:2000-10-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Three-Dimensional Structure of a Plasmodium Falciparum Cyclophilin in Complex with the Potent Anti-Malarial Cyclosporin A
J.Mol.Biol., 298, 2000
1QNH
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Plasmodium falciparum Cyclophilin (double mutant) complexed with Cyclosporin A
Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE
Authors:Peterson, M.R, Hall, D.R, Hunter, W.N.
Deposit date:1999-10-14
Release date:2000-10-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Three-Dimensional Structure of a Plasmodium Falciparum Cyclophilin in Complex with the Potent Anti-Malarial Cyclosporin A
J.Mol.Biol., 298, 2000
1QOI
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U4/U6 snRNP-specific cyclophilin SnuCyp-20
Descriptor: SNUCYP-20
Authors:Reidt, U, Reuter, K, Achsel, T, Ingelfinger, D, Luehrmann, R, Ficner, R.
Deposit date:1999-11-09
Release date:2000-04-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the Human U4/U6 Small Nuclear Ribonucleoproteinparticle-Specificsnucyp-20, a Nuclear Cyclophilin
J.Biol.Chem., 275, 2000
1RMH
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RECOMBINANT CYCLOPHILIN A FROM HUMAN T CELL
Descriptor: AAPF PEPTIDE SUBSTRATE, CYCLOPHILIN A
Authors:Zhao, Y, Ke, H.
Deposit date:1995-07-31
Release date:1996-10-14
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure implies that cyclophilin predominantly catalyzes the trans to cis isomerization.
Biochemistry, 35, 1996

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