4ILZ
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![BU of 4ilz by Molmil](/molmil-images/mine/4ilz) | Structural and kinetic study of an internal substrate binding site of dehaloperoxidase-hemoglobin A from Amphitrite ornata | Descriptor: | 2,4,6-TRIBROMOPHENOL, Dehaloperoxidase A, ISOPROPYL ALCOHOL, ... | Authors: | de Serrano, V.S, Zhao, J, Zhao, J, Franzen, S. | Deposit date: | 2013-01-01 | Release date: | 2013-03-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Structural and Kinetic Study of an Internal Substrate Binding Site in Dehaloperoxidase-Hemoglobin A from Amphitrite ornata. Biochemistry, 52, 2013
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5TPV
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![BU of 5tpv by Molmil](/molmil-images/mine/5tpv) | X-ray structure of WlaRA (TDP-fucose-3,4-ketoisomerase) from Campylobacter jejuni | Descriptor: | PHOSPHATE ION, THYMIDINE-5'-DIPHOSPHATE, WlaRA, ... | Authors: | Holden, H.M, Thoden, J.B, Li, Z.A, Riegert, A.S, Goneau, M.-F, Cunningham, A.M, Vinograd, E, Schoenhofen, I.C, Gilbert, M, Li, J. | Deposit date: | 2016-10-21 | Release date: | 2017-02-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Characterization of the dTDP-Fuc3N and dTDP-Qui3N biosynthetic pathways in Campylobacter jejuni 81116. Glycobiology, 27, 2017
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5TPU
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![BU of 5tpu by Molmil](/molmil-images/mine/5tpu) | x-ray structure of the WlaRB TDP-quinovose 3,4-ketoisomerase from campylobacter jejuni | Descriptor: | CHLORIDE ION, Putative uncharacterized protein, THYMIDINE-5'-DIPHOSPHATE | Authors: | Holden, H.M, Thoden, J.B, Li, J.Z, Riegert, A.S, Goneau, M.-F, Cunningham, A.M, Vinogradov, E, Schoenhofen, I.C, Gilbert, M. | Deposit date: | 2016-10-21 | Release date: | 2017-02-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Characterization of the dTDP-Fuc3N and dTDP-Qui3N biosynthetic pathways in Campylobacter jejuni 81116. Glycobiology, 27, 2017
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5TYH
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![BU of 5tyh by Molmil](/molmil-images/mine/5tyh) | |
3QQA
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![BU of 3qqa by Molmil](/molmil-images/mine/3qqa) | Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni | Descriptor: | CmeR, TAUROCHOLIC ACID | Authors: | Lei, H.T, Routh, M.D, Shen, Z, Su, C.-C, Zhang, Q, Yu, E.W. | Deposit date: | 2011-02-15 | Release date: | 2011-03-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni. Protein Sci., 20, 2011
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3QPS
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![BU of 3qps by Molmil](/molmil-images/mine/3qps) | Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni | Descriptor: | CHOLIC ACID, CmeR | Authors: | Lei, H.T, Routh, M.D, Shen, Z, Su, C.C, Zhang, Q, Yu, E.W. | Deposit date: | 2011-02-14 | Release date: | 2011-03-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.351 Å) | Cite: | Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni. Protein Sci., 20, 2011
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4XD5
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![BU of 4xd5 by Molmil](/molmil-images/mine/4xd5) | Phosphotriesterase variant R2 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-R2, ... | Authors: | Campbell, E, Kaltenbach, M, Tokuriki, N, Jackson, C.J. | Deposit date: | 2014-12-19 | Release date: | 2015-12-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The role of protein dynamics in the evolution of new enzyme function. Nat.Chem.Biol., 12, 2016
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2XF4
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![BU of 2xf4 by Molmil](/molmil-images/mine/2xf4) | Crystal structure of Salmonella enterica serovar typhimurium YcbL | Descriptor: | HYDROXYACYLGLUTATHIONE HYDROLASE, TETRAETHYLENE GLYCOL, ZINC ION | Authors: | Stamp, A, Owen, P, El Omari, K, Nichols, C, Lockyer, M, Lamb, H, Charles, I, Hawkins, A.R, Stammers, D.K. | Deposit date: | 2010-05-20 | Release date: | 2010-07-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and Functional Characterization of Salmonella Enterica Serovar Typhimurium Ycbl: An Unusual Type II Glyoxalase Protein Sci., 19, 2010
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4ORH
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![BU of 4orh by Molmil](/molmil-images/mine/4orh) | Crystal structure of RNF8 bound to the UBC13/MMS2 heterodimer | Descriptor: | E3 ubiquitin-protein ligase RNF8, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2, ... | Authors: | Campbell, S.J, Edwards, R.A, Glover, J.N.M. | Deposit date: | 2014-02-11 | Release date: | 2014-02-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (4.802 Å) | Cite: | Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation. J.Biol.Chem., 287, 2012
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4PCP
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![BU of 4pcp by Molmil](/molmil-images/mine/4pcp) | Crystal structure of Phosphotriesterase variant R0 | Descriptor: | CACODYLATE ION, Phosphotriesterase variant PTE-R0, ZINC ION | Authors: | Campbell, E, Kaltenbach, M, Tokuriki, N, Jackson, C.J. | Deposit date: | 2014-04-16 | Release date: | 2015-05-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | The role of protein dynamics in the evolution of new enzyme function. Nat. Chem. Biol., 12, 2016
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4PBE
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![BU of 4pbe by Molmil](/molmil-images/mine/4pbe) | Phosphotriesterase Variant Rev6 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-revR6, ... | Authors: | Campbell, E, Kaltenbach, M, Tokuriki, N, Jackson, C.J. | Deposit date: | 2014-04-12 | Release date: | 2015-05-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | The role of protein dynamics in the evolution of new enzyme function. Nat. Chem. Biol., 12, 2016
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4JKN
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![BU of 4jkn by Molmil](/molmil-images/mine/4jkn) | Mercury Metallated Pseudomonas aeruginosa Azurin at 1.54 A | Descriptor: | Azurin, MERCURY (II) ION, NITRATE ION, ... | Authors: | Zampino, A.P, Masters, F.M, Bladholm, E.L, Berry, S.B, Panzner, M.J, Ziegler, C.J. | Deposit date: | 2013-03-10 | Release date: | 2014-02-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.536 Å) | Cite: | Mercury metallation of the copper protein azurin and structural insight into possible heavy metal reactivity. J.Inorg.Biochem., 141, 2014
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1YNJ
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![BU of 1ynj by Molmil](/molmil-images/mine/1ynj) | Taq RNA polymerase-Sorangicin complex | Descriptor: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | Authors: | Campbell, E.A, Pavlova, O, Zenkin, N, Leon, F, Irschik, H, Jansen, R, Severinov, K, Darst, S.A. | Deposit date: | 2005-01-24 | Release date: | 2005-03-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase Embo J., 24, 2005
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4PBF
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![BU of 4pbf by Molmil](/molmil-images/mine/4pbf) | Phosphotriesterase variant Rev12 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-revR12, ... | Authors: | Campbell, E, Kaltenbach, M, Tokuriki, N, Jackson, C.J. | Deposit date: | 2014-04-12 | Release date: | 2015-05-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The role of protein dynamics in the evolution of new enzyme function. Nat. Chem. Biol., 12, 2016
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8ATH
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![BU of 8ath by Molmil](/molmil-images/mine/8ath) | CRYSTAL STRUCTURE OF LAMP1 IN COMPLEX WITH FAB-B. | Descriptor: | Fab B Heavy Chain, Fab B Light Chain, Lysosome-associated membrane glycoprotein 1 | Authors: | Mathieu, M, Dupuy, A. | Deposit date: | 2022-08-23 | Release date: | 2023-03-01 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.366 Å) | Cite: | Deciphering cross-species reactivity of LAMP-1 antibodies using deep mutational epitope mapping and AlphaFold. Mabs, 15, 2023
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2A4Z
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![BU of 2a4z by Molmil](/molmil-images/mine/2a4z) | Crystal Structure of human PI3Kgamma complexed with AS604850 | Descriptor: | (5E)-5-[(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)METHYLENE]-1,3-THIAZOLIDINE-2,4-DIONE, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform | Authors: | Camps, M, Ruckle, T, Ji, H, Ardissone, V, Rintelen, F, Shaw, J, Ferrandi, C, Chabert, C, Gillieron, C, Francon, B, Martin, T, Gretener, D, Perrin, D, Leroy, D, Vitte, P.-A, Hirsch, E, Wymann, M.P, Cirillo, R, Schwarz, M.K, Rommel, C. | Deposit date: | 2005-06-30 | Release date: | 2005-09-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis NAT.MED. (N.Y.), 11, 2005
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1FW5
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![BU of 1fw5 by Molmil](/molmil-images/mine/1fw5) | SOLUTION STRUCTURE OF MEMBRANE BINDING PEPTIDE OF SEMLIKI FOREST VIRUS MRNA CAPPING ENZYME NSP1 | Descriptor: | NONSTRUCTURAL PROTEIN NSP1 | Authors: | Lampio, A, Kilpelinen, I, Pesonen, S, Karhi, K, Auvinen, P, Somerharju, P, Kriinen, L. | Deposit date: | 2000-09-21 | Release date: | 2001-09-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Membrane binding mechanism of an RNA virus-capping enzyme. J.Biol.Chem., 275, 2001
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2A5U
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![BU of 2a5u by Molmil](/molmil-images/mine/2a5u) | Crystal Structure of human PI3Kgamma complexed with AS605240 | Descriptor: | (5E)-5-(QUINOXALIN-6-YLMETHYLENE)-1,3-THIAZOLIDINE-2,4-DIONE, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform | Authors: | Camps, M, Ruckle, T, Ji, H, Ardissone, V, Rintelen, F, Shaw, J, Ferrandi, C, Chabert, C, Gillieron, C, Francon, B, Martin, T, Gretener, D, Perrin, D, Leroy, D, Vitte, P.-A, Hirsch, E, Wymann, M.P, Cirillo, R, Schwarz, M.K, Rommel, C. | Deposit date: | 2005-07-01 | Release date: | 2005-09-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis NAT.MED. (N.Y.), 11, 2005
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2ACO
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![BU of 2aco by Molmil](/molmil-images/mine/2aco) | Xray structure of Blc dimer in complex with vaccenic acid | Descriptor: | Outer membrane lipoprotein blc, VACCENIC ACID | Authors: | Campanacci, V, Bishop, R.E, Reese, L, Blangy, S, Tegoni, M, Cambillau, C. | Deposit date: | 2005-07-19 | Release date: | 2006-08-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The membrane bound bacterial lipocalin Blc is a functional dimer with binding preference for lysophospholipids. Febs Lett., 580, 2006
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8IVU
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![BU of 8ivu by Molmil](/molmil-images/mine/8ivu) | Crystal Structure of Human NAMPT in complex with A4276 | Descriptor: | N-[[4-(6-methyl-1,3-benzoxazol-2-yl)phenyl]methyl]pyridine-3-carboxamide, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION | Authors: | Kang, B.G, Cha, S.S. | Deposit date: | 2023-03-28 | Release date: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.09000921 Å) | Cite: | Discovery of a novel NAMPT inhibitor that selectively targets NAPRT-deficient EMT-subtype cancer cells and alleviates chemotherapy-induced peripheral neuropathy. Theranostics, 13, 2023
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6YEN
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![BU of 6yen by Molmil](/molmil-images/mine/6yen) | Crystal structure of AmpC from E. coli with Taniborbactam (VNRX-5133) | Descriptor: | (10aR)-2-(((1r,4R)-4-((2-aminoethyl)amino)cyclohexyl)methyl)-6-carboxy-4-hydroxy-4,10a-dihydro-10H-benzo[5,6][1,2]oxaborinino[2,3-b][1,4,2]oxazaborol-4-uide, (3~{R})-3-[2-[4-(2-azanylethylamino)cyclohexyl]ethanoylamino]-2-oxidanyl-3,4-dihydro-1,2-benzoxaborinine-8-carboxylic acid, 1,2-ETHANEDIOL, ... | Authors: | Lang, P.A, Brem, J, Schofield, C.J. | Deposit date: | 2020-03-25 | Release date: | 2020-06-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.418 Å) | Cite: | Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C beta-Lactamase from Escherichia coli . Biomolecules, 10, 2020
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6YPD
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![BU of 6ypd by Molmil](/molmil-images/mine/6ypd) | Crystal structure of AmpC from E. coli with Cyclic Boronate 3 (CB3 / APC308) | Descriptor: | (3~{S})-2,2-bis(oxidanyl)-3-(phenylmethylsulfanyl)-3,4-dihydro-1,2-benzoxaborinin-2-ium-8-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase, ... | Authors: | Lang, P.A, Brem, J, Schofield, C.J. | Deposit date: | 2020-04-15 | Release date: | 2020-06-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C beta-Lactamase from Escherichia coli . Biomolecules, 10, 2020
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6YEO
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![BU of 6yeo by Molmil](/molmil-images/mine/6yeo) | Crystal structure of AmpC from E. coli with cyclic boronate 2 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, (4~{R})-4-[[4-(aminomethyl)phenyl]carbonylamino]-3,3-bis(oxidanyl)-2-oxa-3-boranuidabicyclo[4.4.0]deca-1(10),6,8-triene-10-carboxylic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Lang, P.A, Schofield, C.J, Brem, J. | Deposit date: | 2020-03-25 | Release date: | 2020-06-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.037 Å) | Cite: | Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C beta-Lactamase from Escherichia coli . Biomolecules, 10, 2020
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8B7S
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![BU of 8b7s by Molmil](/molmil-images/mine/8b7s) | Crystal structure of the Chloramphenicol-inactivating oxidoreductase from Novosphingobium sp | Descriptor: | Chloramphenicol-inactivating oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Zhang, L, Toplak, M, Saleem-Batcha, R, Hoeing, L, Jakob, R.P, Jehmlich, N, von Bergen, M, Maier, T, Teufel, R. | Deposit date: | 2022-10-03 | Release date: | 2022-11-16 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Bacterial Dehydrogenases Facilitate Oxidative Inactivation and Bioremediation of Chloramphenicol. Chembiochem, 24, 2023
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6PEB
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![BU of 6peb by Molmil](/molmil-images/mine/6peb) | Crystal Structure of human NAMPT in complex with NVP-LTM976 | Descriptor: | N-{4-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-3-(pyridin-3-yl)azetidine-1-carboxamide, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION | Authors: | Weihofen, W.A. | Deposit date: | 2019-06-20 | Release date: | 2019-12-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Scaffold Morphing Identifies 3-Pyridyl Azetidine Ureas as Inhibitors of Nicotinamide Phosphoribosyltransferase (NAMPT). Acs Med.Chem.Lett., 10, 2019
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