1JZ2
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![BU of 1jz2 by Molmil](/molmil-images/mine/1jz2) | E. COLI (lacZ) BETA-GALACTOSIDASE-TRAPPED 2-F-GALACTOSYL-ENZYME INTERMEDIATE (ORTHORHOMBIC) | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-deoxy-2-fluoro-beta-D-galactopyranose, Beta-Galactosidase, ... | Authors: | Juers, D.H, McCarter, J.D, Mackenzie, L, Withers, S.G, Matthews, B.W. | Deposit date: | 2001-09-13 | Release date: | 2001-12-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A Structural View of the Action of Escherichia Coli (Lacz) Beta-Galactosidase Biochemistry, 40, 2001
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8A1O
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![BU of 8a1o by Molmil](/molmil-images/mine/8a1o) | Crystal structure of the transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with acrylamide analogue 8 | Descriptor: | (E)-3-chloranyl-3-[(2-chlorophenyl)methylsulfonyl]-N-(5-methoxypyridin-2-yl)prop-2-enamide, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | de Munnik, M, Lang, P.A, Brem, J, Schofield, C.J. | Deposit date: | 2022-06-01 | Release date: | 2023-06-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | High-throughput screen with the l,d-transpeptidase Ldt Mt2 of Mycobacterium tuberculosis reveals novel classes of covalently reacting inhibitors. Chem Sci, 14, 2023
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1JZ3
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8JHN
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![BU of 8jhn by Molmil](/molmil-images/mine/8jhn) | Structure of MMF-GPR109A-G protein complex | Descriptor: | (E)-4-methoxy-4-oxidanylidene-but-2-enoic acid, G protein subunit alpha o1,Guanine nucleotide-binding protein G(o) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Yadav, M.K, Sarma, P, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-05-24 | Release date: | 2024-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Structure-guided engineering of biased-agonism in the human niacin receptor via single amino acid substitution. Nat Commun, 15, 2024
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1JZ4
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1JZ7
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1JYX
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![BU of 1jyx by Molmil](/molmil-images/mine/1jyx) | E. COLI (lacZ) BETA-GALACTOSIDASE IN COMPLEX WITH IPTG | Descriptor: | 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-Galactosidase, DIMETHYL SULFOXIDE, ... | Authors: | Juers, D.H, Matthews, B.W. | Deposit date: | 2001-09-13 | Release date: | 2001-12-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | A Structural View of the Action of Escherichia Coli (Lacz) Beta-Galactosidase Biochemistry, 40, 2001
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1JYV
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6O11
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![BU of 6o11 by Molmil](/molmil-images/mine/6o11) | E. coli cysteine desulfurase SufS C364A with a Cys-aldimine intermediate | Descriptor: | CHLORIDE ION, Cysteine desulfurase, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-CYSTEINE | Authors: | Dunkle, J.A, Frantom, P.A. | Deposit date: | 2019-02-17 | Release date: | 2019-06-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues. J.Biol.Chem., 294, 2019
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6O10
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![BU of 6o10 by Molmil](/molmil-images/mine/6o10) | E. coli cysteine desulfurase SufS | Descriptor: | CHLORIDE ION, Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Dunkle, J.A, Frantom, P.A. | Deposit date: | 2019-02-17 | Release date: | 2019-06-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues. J.Biol.Chem., 294, 2019
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8RJ6
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![BU of 8rj6 by Molmil](/molmil-images/mine/8rj6) | E. coli adenylate kinase in complex with ATP and AMP and Mg2+ as a result of enzymatic AP4A hydrolysis. | Descriptor: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Tischlik, S, Ronge, P, Wolf-Watz, M, Sauer-Eriksson, A.E. | Deposit date: | 2023-12-20 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Magnesium Induced Structural Preorganization in the Active Site of Adenylate Kinase. Sci Adv, 2024
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1JYN
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8PNE
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![BU of 8pne by Molmil](/molmil-images/mine/8pne) | E.coli YihX Wild Type Apo | Descriptor: | Alpha-D-glucose 1-phosphate phosphatase YihX, CALCIUM ION, CHLORIDE ION, ... | Authors: | Zappala, D, Baumann, P, Jin, Y. | Deposit date: | 2023-06-30 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Apo structure of E.coli YihX Wild Type To Be Published
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2P4M
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![BU of 2p4m by Molmil](/molmil-images/mine/2p4m) | High pH structure of Rtms5 H146S variant | Descriptor: | GFP-like non-fluorescent chromoprotein, IODIDE ION | Authors: | Battad, J.M, Wilmann, P.G, Olsen, S, Byres, E, Smith, S.C, Dove, S.G, Turcic, K.N, Devenish, R.J, Rossjohn, J, Prescott, M. | Deposit date: | 2007-03-12 | Release date: | 2007-04-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A structural basis for the pH-dependent increase in fluorescence efficiency of chromoproteins J.Mol.Biol., 368, 2007
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7UO0
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![BU of 7uo0 by Molmil](/molmil-images/mine/7uo0) | E.coli RNaseP Holoenzyme with Mg2+ | Descriptor: | CALCIUM ION, Precursor tRNA substrate G(-1) G(-2), RNase P RNA, ... | Authors: | Huang, W, Taylor, D.J. | Deposit date: | 2022-04-12 | Release date: | 2022-09-28 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P. Nat Commun, 13, 2022
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7UO2
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![BU of 7uo2 by Molmil](/molmil-images/mine/7uo2) | E.coli RNaseP Holoenzyme with Mg2+ | Descriptor: | MAGNESIUM ION, RNase P RNA, Ribonuclease P protein component | Authors: | Huang, W, Taylor, D.J. | Deposit date: | 2022-04-12 | Release date: | 2022-09-28 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P. Nat Commun, 13, 2022
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7UO5
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![BU of 7uo5 by Molmil](/molmil-images/mine/7uo5) | E.coli RNaseP Holoenzyme with Mg2+ | Descriptor: | CALCIUM ION, RNase P RNA, Ribonuclease P protein component | Authors: | Huang, W, Taylor, D.J. | Deposit date: | 2022-04-12 | Release date: | 2022-09-28 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P. Nat Commun, 13, 2022
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6BPL
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![BU of 6bpl by Molmil](/molmil-images/mine/6bpl) | E. coli MsbA in complex with LPS and inhibitor G907 | Descriptor: | (2E)-3-{6-[(1S)-1-(2-chloro-6-cyclopropylphenyl)ethoxy]-4-cyclopropylquinolin-3-yl}prop-2-enoic acid, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-amino-2-deoxy-alpha-D-glucopyranose, ... | Authors: | Ho, H, Koth, C.M, Payandeh, J. | Deposit date: | 2017-11-23 | Release date: | 2018-05-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.908 Å) | Cite: | Structural basis for dual-mode inhibition of the ABC transporter MsbA. Nature, 557, 2018
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6CJA
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1JZ8
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6E9N
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6E9O
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7O0S
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1Q1P
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![BU of 1q1p by Molmil](/molmil-images/mine/1q1p) | E-Cadherin activation | Descriptor: | CALCIUM ION, Epithelial-cadherin | Authors: | Haussinger, D, Stetefeld, J. | Deposit date: | 2003-07-22 | Release date: | 2004-04-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Proteolytic E-cadherin activation followed by solution NMR and X-ray crystallography. Embo J., 23, 2004
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7O9Z
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![BU of 7o9z by Molmil](/molmil-images/mine/7o9z) | Crystal structure of Human Menin in complex with BD-08 | Descriptor: | (~{E})-2-cyano-3-(2~{H}-indazol-6-yl)-~{N}-(2-morpholin-4-ylethyl)prop-2-enamide, 1,2-ETHANEDIOL, GLYCEROL, ... | Authors: | Groves, M.R, Gao, K. | Deposit date: | 2021-04-18 | Release date: | 2022-07-27 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.979 Å) | Cite: | Crystal structure of Human Menin in complex with BD-08 To Be Published
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