6BPL
E. coli MsbA in complex with LPS and inhibitor G907
Summary for 6BPL
Entry DOI | 10.2210/pdb6bpl/pdb |
Descriptor | Lipid A export ATP-binding/permease protein MsbA, MYRISTIC ACID, DIPHOSPHATE, ... (11 entities in total) |
Functional Keywords | abc transporter, inhibitor, lps, msba, lipid transport |
Biological source | Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) |
Total number of polymer chains | 2 |
Total formula weight | 136482.65 |
Authors | Ho, H.,Koth, C.M.,Payandeh, J. (deposition date: 2017-11-23, release date: 2018-05-02, Last modification date: 2020-07-29) |
Primary citation | Ho, H.,Miu, A.,Alexander, M.K.,Garcia, N.K.,Oh, A.,Zilberleyb, I.,Reichelt, M.,Austin, C.D.,Tam, C.,Shriver, S.,Hu, H.,Labadie, S.S.,Liang, J.,Wang, L.,Wang, J.,Lu, Y.,Purkey, H.E.,Quinn, J.,Franke, Y.,Clark, K.,Beresini, M.H.,Tan, M.W.,Sellers, B.D.,Maurer, T.,Koehler, M.F.T.,Wecksler, A.T.,Kiefer, J.R.,Verma, V.,Xu, Y.,Nishiyama, M.,Payandeh, J.,Koth, C.M. Structural basis for dual-mode inhibition of the ABC transporter MsbA. Nature, 557:196-201, 2018 Cited by PubMed: 29720648DOI: 10.1038/s41586-018-0083-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.908 Å) |
Structure validation
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