PDB: 245011 resultsInfo pagesStatus searchChemie searchBIRD

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7M47	DNA Polymerase Lambda, TTP:At Mg2+ Product State Ternary Complex, 60 min Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*GP*TP*AP*CP*T)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... Authors: Jamsen, J.A, Wilson, S.H. Deposit date: 2021-03-21 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.648 Å) Cite: Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
7M4H	DNA Polymerase Lambda, dCTP:At Mn2+ Reaction State Ternary Complex, 225 min Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*AP*CP*C)-3'), ... Authors: Jamsen, J.A, Wilson, S.H. Deposit date: 2021-03-21 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.923 Å) Cite: Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
7M4J	DNA Polymerase Lambda, dCTP:At Mn2+ Product State Ternary Complex, 960 min Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*GP*TP*AP*CP*C)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... Authors: Jamsen, J.A, Wilson, S.H. Deposit date: 2021-03-21 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.377 Å) Cite: Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
7M4B	DNA Polymerase Lambda, TTP:At Mn2+ Product State Ternary Complex, 60 min Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*GP*TP*AP*CP*T)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... Authors: Jamsen, J.A, Wilson, S.H. Deposit date: 2021-03-21 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.66 Å) Cite: Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
7M4A	DNA Polymerase Lambda, TTP:At Mn2+ Product State Ternary Complex, 20 min Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*GP*TP*AP*CP*T)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... Authors: Jamsen, J.A, Wilson, S.H. Deposit date: 2021-03-21 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.868 Å) Cite: Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
7M46	DNA Polymerase Lambda, TTP:At Mg2+ Product State Ternary Complex, 5 min Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*GP*TP*AP*CP*T)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... Authors: Jamsen, J.A, Wilson, S.H. Deposit date: 2021-03-21 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
7M4C	DNA Polymerase Lambda, TTP:At Mn2+ Product State Ternary Complex, 960 min Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*GP*TP*AP*CP*T)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... Authors: Jamsen, J.A, Wilson, S.H. Deposit date: 2021-03-21 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
7M45	DNA Polymerase Lambda, TTP:At Mg2+ Reaction State Ternary Complex, 120 sec Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*GP*TP*AP*CP*T)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... Authors: Jamsen, J.A, Wilson, S.H. Deposit date: 2021-03-21 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.889 Å) Cite: Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
7M4I	DNA Polymerase Lambda, dCTP:At Mn2+ Product State Ternary Complex, 420 min Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*GP*TP*AP*CP*C)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... Authors: Jamsen, J.A, Wilson, S.H. Deposit date: 2021-03-21 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.005 Å) Cite: Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
8EU1	Ancestral PETase 35_442 Mutant F93L Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Polyethylene terephthalate hydrolase, ... Authors: Saunders, J.W, Frkic, R.L, Jackson, C.J. Deposit date: 2022-10-18 Release date: 2023-11-01 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.23 Å) Cite: Ancestral PETase 35_442 Mutant F93L To Be Published
7M4G	DNA Polymerase Lambda, dCTP:At Mg2+ Product State Ternary Complex, 960 min Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*GP*TP*AP*CP*C)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... Authors: Jamsen, J.A, Wilson, S.H. Deposit date: 2021-03-21 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
7M4D	DNA Polymerase Lambda, dCTP:At Ca2+ Ground State Ternary Complex Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, ... Authors: Jamsen, J.A, Wilson, S.H. Deposit date: 2021-03-21 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.817 Å) Cite: Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
7M48	DNA Polymerase Lambda, TTP:At Mg2+ Product State Ternary Complex, 960 min Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*GP*TP*AP*CP*T)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... Authors: Jamsen, J.A, Wilson, S.H. Deposit date: 2021-03-21 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
7NE7	oligopeptidase B from S. proteomaculans with modified hinge region in complex with N-[(1S)-5-amino-1-(chloroacetyl)pentyl]-4-methylbenzenesulfonamide Descriptor: N-[(1S)-5-amino-1-(chloroacetyl)pentyl]-4-methylbenzenesulfonamide, Oligopeptidase B, SPERMINE Authors: Petrenko, D.E, Nikolaeva, A.Y, Lazarenko, V.A, Dorovatovskiy, P.V, Vlaskina, A.V, Mikhailova, A.G, Rakitina, T.V, Timofeev, V.I. Deposit date: 2021-02-03 Release date: 2021-02-17 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The Crystal Structure of N alpha-p-tosyl-lysyl Chloromethylketone-Bound Oligopeptidase B from Serratia Proteamaculans Revealed a New Type of Inhibitor Binding Crystals, 11, 2021
8WL5	X-ray structure of Enterobacter cloacae allose-binding protein in free form Descriptor: 1,2-ETHANEDIOL, Allose ABC transporter Authors: Kamitori, S. Deposit date: 2023-09-29 Release date: 2023-10-25 Method: X-RAY DIFFRACTION (1.87 Å) Cite: X-ray structures of Enterobacter cloacae allose-binding protein in complexes with monosaccharides demonstrate its unique recognition mechanism for high affinity to allose. Biochem.Biophys.Res.Commun., 682, 2023
7OCJ	Crystal structure of E.coli LexA in complex with nanobody NbSOS2(Nb14509) Descriptor: 1,2-ETHANEDIOL, LexA repressor, NbSOS2 (14509) Authors: Maso, L, Vascon, F, Chinellato, M, Pardon, E, Steyaert, J, Angelini, A, Tondi, D, Cendron, L. Deposit date: 2021-04-27 Release date: 2022-10-26 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Nanobodies targeting LexA autocleavage disclose a novel suppression strategy of SOS-response pathway. Structure, 30, 2022
4WF6	Anthrax toxin lethal factor with bound small molecule inhibitor MK-31 Descriptor: 1,2-ETHANEDIOL, Lethal factor, N~2~-[(4-fluoro-3-methylphenyl)sulfonyl]-N-hydroxy-D-alaninamide, ... Authors: Maize, K.M, De la Mora-Rey, T, Finzel, B.C. Deposit date: 2014-09-12 Release date: 2015-09-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.6521 Å) Cite: Probing the S2' Subsite of the Anthrax Toxin Lethal Factor Using Novel N-Alkylated Hydroxamates. J.Med.Chem., 58, 2015
7NC9	Glutathione-S-transferase GliG mutant H26N Descriptor: 1,2-ETHANEDIOL, Glutathione S-transferase GliG Authors: Groll, M, Huber, E.M. Deposit date: 2021-01-28 Release date: 2021-05-12 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin. Angew.Chem.Int.Ed.Engl., 60, 2021
7NCD	Glutathione-S-transferase GliG mutant N27D Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Glutathione S-transferase GliG, ... Authors: Groll, M, Huber, E.M. Deposit date: 2021-01-28 Release date: 2021-05-12 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin. Angew.Chem.Int.Ed.Engl., 60, 2021
7NCO	Glutathione-S-transferase GliG mutant K127R Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Glutathione S-transferase GliG Authors: Groll, M, Huber, E.M. Deposit date: 2021-01-29 Release date: 2021-05-12 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin. Angew.Chem.Int.Ed.Engl., 60, 2021
7NCL	Glutathione-S-transferase GliG mutant E82Q Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Glutathione S-transferase GliG Authors: Groll, M, Huber, E.M. Deposit date: 2021-01-29 Release date: 2021-05-12 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin. Angew.Chem.Int.Ed.Engl., 60, 2021
7NCP	Glutathione-S-transferase GliG mutant K127A Descriptor: 1,2-ETHANEDIOL, Glutathione S-transferase GliG, SODIUM ION Authors: Groll, M, Huber, E.M. Deposit date: 2021-01-29 Release date: 2021-05-12 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin. Angew.Chem.Int.Ed.Engl., 60, 2021
7NNH	Cryo-EM structure of VAR2CSA FCR3 domain DBL5/6 Descriptor: Erythrocyte membrane protein 1 Authors: Wang, K.T, Dagil, R, Salanti, A, Gourdon, P.E. Deposit date: 2021-02-24 Release date: 2021-06-02 Last modified: 2025-07-09 Method: ELECTRON MICROSCOPY (4 Å) Cite: Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding. Nat Commun, 12, 2021
7N7A	crystal structure of the dTDP-Qui3N N-formyltransferase from Helicobacter canadensis, apo form Descriptor: 1,2-ETHANEDIOL, Formyl_trans_N domain-containing protein Authors: Heisdorf, C.J, Thoden, J.B, Holden, H.M. Deposit date: 2021-06-10 Release date: 2021-06-23 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Investigation of the enzymes required for the biosynthesis of an unusual formylated sugar in the emerging human pathogen Helicobacter canadensis. Protein Sci., 30, 2021
7NNB	Crystal structure of Mycobacterium tuberculosis ArgB in complex with 2,8-bis(trifluoromethyl)quinolin-4-ol. Descriptor: 1,2-ETHANEDIOL, 2,8-bis(trifluoromethyl)quinolin-4-ol, Acetylglutamate kinase, ... Authors: Mendes, V, Thomas, S.E, Cory-Wright, J, Blundell, T.L. Deposit date: 2021-02-24 Release date: 2021-06-30 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.186 Å) Cite: A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021

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