7Y7H
 
 | | Structure of the Bacterial Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAC) | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | | Deposit date: | 2022-06-22 | | Release date: | 2023-10-25 | | Last modified: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (2.51 Å) | | Cite: | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
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8CO2
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7EQF
 | | Crystal Structure of a Transcription Factor in complex with Ligand | | Descriptor: | (6~{R})-3-methyl-8-[(2~{S},4~{R},5~{S},6~{R})-6-methyl-5-[(2~{S},4~{R},5~{R},6~{R})-6-methyl-4-[(2~{S},5~{S},6~{S})-6-methyl-5-[(2~{S},4~{R},5~{S},6~{R})-6-methyl-5-[(2~{S},4~{S},5~{S},6~{R})-6-methyl-4-[(2~{S},5~{S},6~{S})-6-methyl-5-oxidanyl-oxan-2-yl]oxy-5-oxidanyl-oxan-2-yl]oxy-4-oxidanyl-oxan-2-yl]oxy-oxan-2-yl]oxy-5-oxidanyl-oxan-2-yl]oxy-4-oxidanyl-oxan-2-yl]oxy-1,6,11-tris(oxidanyl)-5,6-dihydrobenzo[a]anthracene-7,12-dione, TetR/AcrR family transcriptional regulator | | Authors: | Uehara, S, Tsugita, A, Matsui, T, Yokoyama, T, Ostash, I, Ostash, B, Tanaka, Y. | | Deposit date: | 2021-05-01 | | Release date: | 2022-04-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | The carbohydrate tail of landomycin A is responsible for its interaction with the repressor protein LanK.
Febs J., 289, 2022
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7OZ3
 | | S. agalactiae BusR in complex with its busA-promotor DNA | | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, GntR family transcriptional regulator, pBusA_for, ... | | Authors: | Bandera, A.M, Witte, G. | | Deposit date: | 2021-06-25 | | Release date: | 2021-08-11 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (4.46 Å) | | Cite: | BusR senses bipartite DNA binding motifs by a unique molecular ruler architecture.
Nucleic Acids Res., 49, 2021
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7EN6
 | | The crystal structure of Escherichia coli MurR in apo form | | Descriptor: | HTH-type transcriptional regulator MurR, PHOSPHATE ION | | Authors: | Zhang, Y, Chen, W, Ji, Q. | | Deposit date: | 2021-04-16 | | Release date: | 2022-04-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.276 Å) | | Cite: | Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli.
Nucleic Acids Res., 50, 2022
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7EN5
 | | The crystal structure of Escherichia coli MurR in complex with N-acetylglucosamine-6-phosphate | | Descriptor: | 2-METHOXYETHANOL, 2-acetamido-2-deoxy-6-O-phosphono-beta-D-glucopyranose, GLYCEROL, ... | | Authors: | Zhang, Y, Chen, W, Ji, Q. | | Deposit date: | 2021-04-16 | | Release date: | 2022-04-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli.
Nucleic Acids Res., 50, 2022
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7EN7
 | | The crystal structure of Escherichia coli MurR in complex with N-acetylmuramic-acid-6-phosphate | | Descriptor: | (2R)-2-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-bis(oxidanyl)-6-(phosphonooxymethyl)oxan-4-yl]oxypropanoic acid, HTH-type transcriptional regulator MurR | | Authors: | Zhang, Y, Chen, W, Ji, Q. | | Deposit date: | 2021-04-16 | | Release date: | 2022-04-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.22 Å) | | Cite: | Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli.
Nucleic Acids Res., 50, 2022
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6X6F
 | | The structure of Pf6r from the filamentous phage Pf6 of Pseudomonas aeruginosa PA01 | | Descriptor: | NITRATE ION, Pf6r | | Authors: | Michie, K.A, Norrian, P, Duggin, I.G, McDougald, D, Rice, S.A. | | Deposit date: | 2020-05-28 | | Release date: | 2021-04-07 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.735 Å) | | Cite: | The Repressor C Protein, Pf4r, Controls Superinfection of Pseudomonas aeruginosa PAO1 by the Pf4 Filamentous Phage and Regulates Host Gene Expression.
Viruses, 13, 2021
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6EJZ
 | | Tryptophan Repressor TrpR from E.coli variant S88Y with Indole-3-acetic acid as ligand | | Descriptor: | 1,2-ETHANEDIOL, 1H-INDOL-3-YLACETIC ACID, SULFATE ION, ... | | Authors: | Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. | | Deposit date: | 2017-09-24 | | Release date: | 2019-02-06 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A biosensor for the direct visualization of auxin
Nature, 2021
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8BNY
 | | Structure of the tetramerization domain of pLS20 conjugation repressor Rco | | Descriptor: | CHLORIDE ION, Immunity repressor protein | | Authors: | Bernardo, N, Crespo, I, Meijer, W.J.J, Boer, D.R. | | Deposit date: | 2022-11-14 | | Release date: | 2023-04-19 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.429 Å) | | Cite: | A tetramerization domain in prokaryotic and eukaryotic transcription regulators homologous to p53.
Acta Crystallogr D Struct Biol, 79, 2023
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5X8U
 | | Crystal Structure of the wild Human ROR gamma Ligand Binding Domain. | | Descriptor: | Nuclear receptor ROR-gamma, Nuclear receptor coactivator 1 | | Authors: | Noguchi, M, Nomura, A, Murase, K, Doi, S, Yamaguchi, K, Adachi, T. | | Deposit date: | 2017-03-03 | | Release date: | 2017-06-07 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Ternary complex of human ROR gamma ligand-binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment
Genes Cells, 22, 2017
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5X8W
 | | Crystal Structure of the mutant Human ROR gamma Ligand Binding Domain. | | Descriptor: | Nuclear receptor ROR-gamma, Nuclear receptor coactivator 1 | | Authors: | Noguchi, M, Nomura, A, Murase, K, Doi, S, Yamaguchi, K, Adachi, T. | | Deposit date: | 2017-03-03 | | Release date: | 2017-06-07 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Ternary complex of human ROR gamma ligand-binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment
Genes Cells, 22, 2017
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7RGU
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6YJ2
 | | Structural and DNA binding studies of the transcriptional repressor Rv2506 (BkaR) from Mycobacterium tuberculosis supports a role in L-Leucine catabolism | | Descriptor: | GLYCEROL, Probable transcriptional regulatory protein (Probably TetR-family) | | Authors: | Keep, N.H, Pritchard, J.E, Sula, A, Cole, A.R, Kendall, S.L. | | Deposit date: | 2020-04-02 | | Release date: | 2021-04-14 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural and DNA binding studies of the transcriptional repressor Rv2506 (BkaR) from Mycobacterium tuberculosis supports a role in L-Leucine catabolism
To be published
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1SD7
 | | Crystal Structure of a SeMet derivative of MecI at 2.65 A | | Descriptor: | Methicillin resistance regulatory protein mecI | | Authors: | Safo, M.K, Zhao, Q, Musayev, F.N, Robinson, H, Scarsdale, N, Archer, G.L. | | Deposit date: | 2004-02-13 | | Release date: | 2004-02-24 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Crystal structures of the BlaI repressor from Staphylococcus aureus and its complex with DNA: insights into transcriptional regulation of the bla and mec operons
J.Bacteriol., 187, 2005
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5WHM
 | | Crystal Structure of IclR Family Transcriptional Regulator from Brucella abortus | | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, CALCIUM ION, ... | | Authors: | Kim, Y, Wu, R, Tesar, C, Endres, M, Babnigg, G, Crosson, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2017-07-17 | | Release date: | 2017-08-23 | | Last modified: | 2019-11-27 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Molecular control of gene expression byBrucellaBaaR, an IclR-type transcriptional repressor.
J. Biol. Chem., 293, 2018
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5Y2W
 | | Structure of Synechocystis PCC6803 CcmR regulatory domain in complex with 2-PG | | Descriptor: | 2-PHOSPHOGLYCOLIC ACID, Rubisco operon transcriptional regulator | | Authors: | Jiang, Y.L, Wang, X.P, Sun, H, Cheng, W, Cao, D.D, Han, S.J, Li, W.F, Chen, Y, Zhou, C.Z. | | Deposit date: | 2017-07-27 | | Release date: | 2017-12-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Coordinating carbon and nitrogen metabolic signaling through the cyanobacterial global repressor NdhR.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5JGC
 | | Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal topless domain (1-209) L111A, L130A, L179A and I195A mutant | | Descriptor: | Protein TPR1, ZINC ION | | Authors: | Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K. | | Deposit date: | 2016-04-20 | | Release date: | 2017-07-05 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
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7JT1
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7JSS
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6N7O
 | | Crystal structure of GIL01 gp7 | | Descriptor: | GIL01 gp7, IODIDE ION | | Authors: | Caveney, N.A, Strynadka, N.C.J. | | Deposit date: | 2018-11-27 | | Release date: | 2019-05-15 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural Insights into Bacteriophage GIL01 gp7 Inhibition of Host LexA Repressor.
Structure, 27, 2019
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1SD6
 | | Crystal Structure of Native MecI at 2.65 A | | Descriptor: | Methicillin resistance regulatory protein mecI | | Authors: | Safo, M.K, Zhao, Q, Musayev, F.N, Robinson, H, Scarsdale, N, Archer, G.L. | | Deposit date: | 2004-02-13 | | Release date: | 2004-02-24 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Crystal structures of the BlaI repressor from Staphylococcus aureus and its complex with DNA: insights into transcriptional regulation of the bla and mec operons
J.Bacteriol., 187, 2005
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5MRU
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4UIG
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8A0A
 | | Bacillus subtilis SPbeta prophage master regulator MrpR | | Descriptor: | Bacillus subtilis SPbeta prophage master regulator MrpR | | Authors: | Czech, L, Bange, G. | | Deposit date: | 2022-05-27 | | Release date: | 2023-06-14 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural and functional characterization of MrpR, the master repressor of the Bacillus subtilis prophage SP beta.
Nucleic Acids Res., 51, 2023
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