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6OUI	Carbonic Anhydrase IX mimic complexed with benzene sulfonamide MB11-710A Descriptor: 3-{[(4-hydroxybutyl)carbamoyl]amino}benzene-1-sulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... Authors: Kota, A, McKenna, R. Deposit date: 2019-05-04 Release date: 2020-05-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.528 Å) Cite: Carbonic Anhydrase IX mimic complexed with ureido benzene sulfonamide MB11-710A To Be Published
6OUH	Carbonic Anhydrase II mimic complexed with benzene sulfonamide MB11-710A Descriptor: 3-{[(4-hydroxybutyl)carbamoyl]amino}benzene-1-sulfonamide, Carbonic anhydrase 2, GLYCEROL, ... Authors: Kota, A, McKenna, R. Deposit date: 2019-05-04 Release date: 2020-05-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.449 Å) Cite: Carbonic Anhydrase II mimic complexed with benzene sulfonamide MB11-710A To Be Published
6OUF	Carbonic Anhydrase IX mimic complexed with benzene sulfonamide MB11-707A Descriptor: 4-{[(4-hydroxybutyl)carbamoyl]amino}benzene-1-sulfonamide, Carbonic anhydrase 2, GLYCEROL, ... Authors: Kota, A, McKenna, R. Deposit date: 2019-05-04 Release date: 2020-05-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.358 Å) Cite: Carbonic Anhydrase IX mimic complexed with ureido benzene sulfonamide MB9-561B To Be Published
6OUE	Carbonic Anhydrase II complexed with benzene sulfonamide MB11-707A Descriptor: 4-{[(4-hydroxybutyl)carbamoyl]amino}benzene-1-sulfonamide, Carbonic anhydrase 2, GLYCEROL, ... Authors: Kota, A, McKenna, R. Deposit date: 2019-05-04 Release date: 2020-05-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.415 Å) Cite: Carbonic Anhydrase II complexed with ureido benzene sulfonamide MB11-707A To Be Published
6OUD	Carbonic Anhydrase IX mimic complexed with benzene sulfonamide MB11-694B Descriptor: 4-{[(2-hydroxyethyl)carbamoyl]amino}benzene-1-sulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... Authors: Kota, A, McKenna, R. Deposit date: 2019-05-04 Release date: 2020-05-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.256 Å) Cite: Carbonic Anhydrase IX mimic complexed with benzene sulfonamide MB11-694B To Be Published
6OUB	Carbonic Anhydrase II complexed with benzene sulfonamide MB11-694B Descriptor: 4-{[(2-hydroxyethyl)carbamoyl]amino}benzene-1-sulfonamide, Carbonic anhydrase 2, GLYCEROL, ... Authors: Kota, A, McKenna, R. Deposit date: 2019-05-04 Release date: 2020-05-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.418 Å) Cite: Carbonic Anhydrase II complexed with ureido benzene sulfonamide MB11-694B To Be Published
6OTQ	Carbonic Anhydrase II complexed with ureic benzene sulfonamide MB10-596B Descriptor: 4-hydroxy-3-{[(4-hydroxybutyl)carbamoyl]amino}benzene-1-sulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... Authors: Kota, A, McKenna, R. Deposit date: 2019-05-03 Release date: 2020-05-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.467 Å) Cite: Carbonic Anhydrase II complexed with benzene sulfonamide MB9-561B To Be Published
6OTP	Carbonic Anhydrase II complexed with ureic benzene sulfonamide MB10-586B Descriptor: 4-hydroxy-3-({[2-(pyridin-2-yl)ethyl]carbamoyl}amino)benzene-1-sulfonamide, Carbonic anhydrase 2, ZINC ION Authors: Kota, A, McKenna, R. Deposit date: 2019-05-03 Release date: 2020-05-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.466 Å) Cite: Carbonic Anhydrase IX mimic complexed with ureido benzene sulfonamide MB9-561B To Be Published
6OTO	Carbonic Anhydrase II complexed with ureic benzene sulfonamide MB9-561B Descriptor: 4-hydroxy-3-({[(pyridin-4-yl)methyl]carbamoyl}amino)benzene-1-sulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... Authors: Kota, A, McKenna, R. Deposit date: 2019-05-03 Release date: 2020-05-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.496 Å) Cite: Carbonic Anhydrase II complexed with ureido benzene sulfonamide MB9-561B To Be Published
6OTM	Carbonic Anhydrase IX mimic complexed with ureic benzene sulfonamide MB10-586B Descriptor: 4-hydroxy-3-({[2-(pyridin-2-yl)ethyl]carbamoyl}amino)benzene-1-sulfonamide, Carbonic anhydrase 2, GLYCEROL, ... Authors: Kota, A, McKenna, R. Deposit date: 2019-05-03 Release date: 2020-05-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.307 Å) Cite: Carbonic Anhydrase IX mimic complexed with ureido benzene sulfonamide MB9-561B To Be Published
6OTK	Carbonic Anhydrase IX mimic complexed with ureido benzene sulfonamide MB10-596B Descriptor: 4-hydroxy-3-{[(4-hydroxybutyl)carbamoyl]amino}benzene-1-sulfonamide, Carbonic anhydrase 2, GLYCEROL, ... Authors: Kota, A, McKenna, R. Deposit date: 2019-05-03 Release date: 2020-05-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.123 Å) Cite: Carbonic Anhydrase IX mimic complexed with ureido benzene sulfonamide MB9-561B To Be Published
6OTI	Carbonic Anhydrase IX mimic complexed with ureic benzene sulfonamide MB9-561B Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-hydroxy-3-({[(pyridin-4-yl)methyl]carbamoyl}amino)benzene-1-sulfonamide, Carbonic anhydrase 2, ... Authors: Kota, A, McKenna, R. Deposit date: 2019-05-03 Release date: 2020-05-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2 Å) Cite: Carbonic Anhydrase IX mimic complexed with ureido benzene sulfonamide MB9-561B To Be Published
6OE1	Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects Descriptor: 2-(2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)-N-(4-sulfamoylphenyl)acetamide, Carbonic anhydrase 2, GLYCEROL, ... Authors: Peat, T.S. Deposit date: 2019-03-27 Release date: 2019-06-12 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects. Eur.J.Med.Chem., 177, 2019
6OE0	Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects Descriptor: 2-(2,4-dioxo-1,3-diazaspiro[4.6]undecan-3-yl)-N-(4-sulfamoylphenyl)acetamide, Carbonic anhydrase 2, GLYCEROL, ... Authors: Peat, T.S. Deposit date: 2019-03-27 Release date: 2019-06-12 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects. Eur.J.Med.Chem., 177, 2019
6ODZ	Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects Descriptor: 2-(2,4-dioxo-1,3-diazaspiro[4.4]nonan-3-yl)-N-(4-sulfamoylphenyl)acetamide, Carbonic anhydrase 2, GLYCEROL, ... Authors: Peat, T.S. Deposit date: 2019-03-27 Release date: 2019-06-12 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects. Eur.J.Med.Chem., 177, 2019
6NM0	Selective inhibition of carbonic anhydrase IX activity, using compound SLC-149, displays limited anticancer effects in breast cancer cell lines Descriptor: 4-[3-(2,4-difluorophenyl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl]benzene-1-sulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... Authors: Singh, S, McKenna, R. Deposit date: 2019-01-10 Release date: 2020-01-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.44 Å) Cite: Inhibition of Carbonic Anhydrase Using SLC-149: Support for a Noncatalytic Function of CAIX in Breast Cancer. J.Med.Chem., 64, 2021
6NLV	Selective inhibition of carbonic anhydrase IX activity, using compound SLC-149, displays limited anticancer effects in breast cancer cell lines Descriptor: 4-[3-(2,4-difluorophenyl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl]benzene-1-sulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... Authors: Singh, S, McKenna, R. Deposit date: 2019-01-09 Release date: 2020-01-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.794 Å) Cite: Inhibition of Carbonic Anhydrase Using SLC-149: Support for a Noncatalytic Function of CAIX in Breast Cancer. J.Med.Chem., 64, 2021
6NJ6	Thermostable variant of human carbonic anhydrase with tetrazine 2.0 at site 186 reacted with sTCO in crystallo Descriptor: Carbonic anhydrase 2, GLYCEROL, METHANOL, ... Authors: Kean, K.M, Karplus, P.A. Deposit date: 2019-01-02 Release date: 2019-10-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Immobilization of Proteins with Controlled Load and Orientation. ACS Appl Mater Interfaces, 11, 2019
6NJ5	Thermostable variant of human carbonic anhydrase II with disordered tetrazine 2.0 at site 233 Descriptor: Carbonic anhydrase 2, ZINC ION Authors: Kean, K.M, Karplus, P.A. Deposit date: 2019-01-02 Release date: 2019-10-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Immobilization of Proteins with Controlled Load and Orientation. ACS Appl Mater Interfaces, 11, 2019
6NJ4	Thermostable variant of human carbonic anhydrase with disordered tetrazine 2.0 reacted with strained trans-cyclooctene at site 233 Descriptor: Carbonic anhydrase 2, ZINC ION Authors: Kean, K.M, Karplus, P.A. Deposit date: 2019-01-02 Release date: 2019-10-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Immobilization of Proteins with Controlled Load and Orientation. ACS Appl Mater Interfaces, 11, 2019
6NJ3	Thermostable variant of human carbonic anhydrase with ordered tetrazine 2.0 at site 233 Descriptor: ACETATE ION, Carbonic anhydrase 2, ZINC ION Authors: Kean, K.M, Karplus, P.A. Deposit date: 2019-01-02 Release date: 2019-10-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.01 Å) Cite: Immobilization of Proteins with Controlled Load and Orientation. ACS Appl Mater Interfaces, 11, 2019
6NJ2	thermostable carbonic anhydrase II variant with tetrazine 2.0 at site 186 Descriptor: Carbonic anhydrase 2, GLYCEROL, SULFATE ION, ... Authors: Kean, K.M, Karplus, P.A. Deposit date: 2019-01-02 Release date: 2019-10-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Immobilization of Proteins with Controlled Load and Orientation. ACS Appl Mater Interfaces, 11, 2019
6MBY	Carbonic Anhydrase II in complex with Ferulic Acid Descriptor: 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... Authors: Lomelino, C.L, McKenna, R. Deposit date: 2018-08-30 Release date: 2019-03-13 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.496 Å) Cite: Carbonic anhydrase II in complex with carboxylic acid-based inhibitors. Acta Crystallogr F Struct Biol Commun, 75, 2019
6MBV	Carbonic Anhydrase II in complex with Nicotinic Acid Descriptor: Carbonic anhydrase 2, GLYCEROL, NICOTINIC ACID, ... Authors: Lomelino, C.L, McKenna, R. Deposit date: 2018-08-30 Release date: 2019-03-13 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.695 Å) Cite: Carbonic anhydrase II in complex with carboxylic acid-based inhibitors. Acta Crystallogr F Struct Biol Commun, 75, 2019
6LVA	Cu- Carbonic Anhydrase II pH 7.8 20 atm CO2 Descriptor: CARBON DIOXIDE, COPPER (II) ION, Carbonic anhydrase 2, ... Authors: Kim, C.U, Kim, J.K. Deposit date: 2020-02-02 Release date: 2020-08-19 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Elucidating the role of metal ions in carbonic anhydrase catalysis. Nat Commun, 11, 2020

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