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3ATH	Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with four AKGs as substrates and allosteric effectors Descriptor: 2-OXOGLUTARIC ACID, PYRIDOXAL-5'-PHOSPHATE, Putative uncharacterized protein PH0207 Authors: Okada, K, Angkawidjaja, C, Koga, Y, Takano, K, Kanaya, S. Deposit date: 2011-01-05 Release date: 2012-01-18 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.69 Å) Cite: Characterization of kynurenine aminotransferase from hyperthermophilic archaeon: enzymatic activity for conversion to kynurenic acid is allosterically regulated by alpha-ketoglutaric acid cooperatively with kynurenine To be Published
3AV7	Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with PMP, KYN as substrates and KYA as products Descriptor: (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-hydroxyquinoline-2-carboxylic acid, ... Authors: Okada, K, Angkawidjaja, C, Koga, Y, Takano, K, Kanaya, S. Deposit date: 2011-02-23 Release date: 2012-03-07 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Structural insight into kynurenic acid excretion mechanisms of kynurenine aminotransferase in the hyperthermophilic archaeon Pyrococcus horikoshii To be Published
3ASA	Crystal structure of apo-LL-diaminopimelate aminotransferase from Chlamydia trachomatis Descriptor: LL-diaminopimelate aminotransferase Authors: Watanabe, N, James, M.N. Deposit date: 2010-12-10 Release date: 2011-08-31 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: The Structure of ll-Diaminopimelate Aminotransferase from Chlamydia trachomatis: Implications for Its Broad Substrate Specificity. J.Mol.Biol., 411, 2011
3B1E	Crystal structure of betaC-S lyase from Streptococcus anginosus in complex with L-serine: alpha-Aminoacrylate form Descriptor: 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ... Authors: Kezuka, Y, Yoshida, Y, Nonaka, T. Deposit date: 2011-06-29 Release date: 2012-06-27 Last modified: 2017-10-11 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Structural insights into catalysis by beta C-S lyase from Streptococcus anginosus Proteins, 80, 2012
3B1C	Crystal structure of betaC-S lyase from Streptococcus anginosus: Internal aldimine form Descriptor: BetaC-S lyase, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... Authors: Kezuka, Y, Yoshida, Y, Nonaka, T. Deposit date: 2011-06-29 Release date: 2012-06-27 Last modified: 2014-01-22 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Structural insights into catalysis by beta C-S lyase from Streptococcus anginosus Proteins, 80, 2012
3B1D	Crystal structure of betaC-S lyase from Streptococcus anginosus in complex with L-serine: External aldimine form Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BetaC-S lyase, PYRIDOXAL-5'-PHOSPHATE, ... Authors: Kezuka, Y, Yoshida, Y, Nonaka, T. Deposit date: 2011-06-29 Release date: 2012-06-27 Last modified: 2017-10-11 Method: X-RAY DIFFRACTION (1.66 Å) Cite: Structural insights into catalysis by beta C-S lyase from Streptococcus anginosus Proteins, 80, 2012
3B46	Crystal Structure of Bna3p, a Putative Kynurenine Aminotransferase from Saccharomyces cerevisiae Descriptor: Aminotransferase BNA3 Authors: Wogulis, M. Deposit date: 2007-10-23 Release date: 2008-02-19 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2 Å) Cite: Identification of Formyl Kynurenine Formamidase and Kynurenine Aminotransferase from Saccharomyces cerevisiae Using Crystallographic, Bioinformatic and Biochemical Evidence. Biochemistry, 47, 2008
5QR1	PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z396380540 Descriptor: 5-aminolevulinate synthase, erythroid-specific, mitochondrial, ... Authors: Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. Deposit date: 2019-05-22 Release date: 2019-08-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.44 Å) Cite: PanDDA analysis group deposition To Be Published
5QQQ	PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z2856434857 Descriptor: 3-[(thiomorpholin-4-yl)methyl]phenol, 5-aminolevulinate synthase, erythroid-specific, ... Authors: Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. Deposit date: 2019-05-22 Release date: 2019-08-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.93 Å) Cite: PanDDA analysis group deposition To Be Published
5QRA	PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z1101755952 Descriptor: 5-aminolevulinate synthase, erythroid-specific, mitochondrial, ... Authors: Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. Deposit date: 2019-05-22 Release date: 2019-08-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.72 Å) Cite: PanDDA analysis group deposition To Be Published
5QQW	PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z136583524 Descriptor: 2-methyl-N-(pyridin-4-yl)furan-3-carboxamide, 5-aminolevulinate synthase, erythroid-specific, ... Authors: Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. Deposit date: 2019-05-22 Release date: 2019-08-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.56 Å) Cite: PanDDA analysis group deposition To Be Published
5QRC	PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z31721798 Descriptor: 3-cyclohexyl-1-(morpholin-4-yl)propan-1-one, 5-aminolevulinate synthase, erythroid-specific, ... Authors: Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. Deposit date: 2019-05-22 Release date: 2019-08-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.82 Å) Cite: PanDDA analysis group deposition To Be Published
5QQS	PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z275151340 Descriptor: 4-chloro-N-cyclopentyl-1-methyl-1H-pyrazole-3-carboxamide, 5-aminolevulinate synthase, erythroid-specific, ... Authors: Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. Deposit date: 2019-05-22 Release date: 2019-08-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.85 Å) Cite: PanDDA analysis group deposition To Be Published
5QR7	PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z57299529 Descriptor: 5-aminolevulinate synthase, erythroid-specific, mitochondrial, ... Authors: Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. Deposit date: 2019-05-22 Release date: 2019-08-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.74 Å) Cite: PanDDA analysis group deposition To Be Published
5QQR	PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z1171217421 Descriptor: 1-[(2-methyl-1,3-thiazol-5-yl)methyl]piperazine, 5-aminolevulinate synthase, erythroid-specific, ... Authors: Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. Deposit date: 2019-05-22 Release date: 2019-08-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.46 Å) Cite: PanDDA analysis group deposition To Be Published
5QR6	PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z44567722 Descriptor: 5-aminolevulinate synthase, erythroid-specific, mitochondrial, ... Authors: Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. Deposit date: 2019-05-22 Release date: 2019-08-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.52 Å) Cite: PanDDA analysis group deposition To Be Published
5QR2	PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z1348371854 Descriptor: 5-(1,4-oxazepan-4-yl)pyridine-2-carbonitrile, 5-aminolevulinate synthase, erythroid-specific, ... Authors: Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. Deposit date: 2019-05-22 Release date: 2019-08-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.66 Å) Cite: PanDDA analysis group deposition To Be Published
5QQY	PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z2856434899 Descriptor: 1-[(2,5-dihydrothiophen-3-yl)methyl]piperidin-4-ol, 5-aminolevulinate synthase, erythroid-specific, ... Authors: Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. Deposit date: 2019-05-22 Release date: 2019-08-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.49 Å) Cite: PanDDA analysis group deposition To Be Published
5QRE	PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z117233350 Descriptor: 3-ethyl-5-methyl-N-(5-methyl-1,2-oxazol-3-yl)-1,2-oxazole-4-carboxamide, 5-aminolevulinate synthase, erythroid-specific, ... Authors: Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. Deposit date: 2019-05-22 Release date: 2019-08-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.67 Å) Cite: PanDDA analysis group deposition To Be Published
5QR5	PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z2241115980 Descriptor: 1-[(furan-2-yl)methyl]-4-(methylsulfonyl)piperazine, 5-aminolevulinate synthase, erythroid-specific, ... Authors: Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. Deposit date: 2019-05-22 Release date: 2019-08-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.49 Å) Cite: PanDDA analysis group deposition To Be Published
5QQX	PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z373768900 Descriptor: 5-aminolevulinate synthase, erythroid-specific, mitochondrial, ... Authors: Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. Deposit date: 2019-05-22 Release date: 2019-08-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.5 Å) Cite: PanDDA analysis group deposition To Be Published
5QRD	PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z1328968520 Descriptor: 4-[(2-methylsulfonylimidazol-1-yl)methyl]-1,3-thiazole, 5-aminolevulinate synthase, erythroid-specific, ... Authors: Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. Deposit date: 2019-05-22 Release date: 2019-08-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.76 Å) Cite: PanDDA analysis group deposition To Be Published
5QR0	PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z730649594 Descriptor: 5-aminolevulinate synthase, erythroid-specific, mitochondrial, ... Authors: Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. Deposit date: 2019-05-22 Release date: 2019-08-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.65 Å) Cite: PanDDA analysis group deposition To Be Published
5QQZ	PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z1675346324 Descriptor: 5-aminolevulinate synthase, erythroid-specific, mitochondrial, ... Authors: Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. Deposit date: 2019-05-22 Release date: 2019-08-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.55 Å) Cite: PanDDA analysis group deposition To Be Published
5QR4	PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z2856434826 Descriptor: 5-aminolevulinate synthase, erythroid-specific, mitochondrial, ... Authors: Bezerra, G.A, Foster, W, Bailey, H, Shrestha, L, Krojer, T, Talon, R, Brandao-Neto, J, Douangamath, A, Nicola, B.B, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Brennan, P.E, Yue, W.W. Deposit date: 2019-05-22 Release date: 2019-08-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.57 Å) Cite: PanDDA analysis group deposition To Be Published

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