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8DK8	Polymorphism in SARS-CoV-2 Nsp5 main protease reveals differences in cleavage of viral and host substrates Descriptor: 3C-like proteinase nsp5 Authors: Khan, M.B, Lu, J, Young, H.S, Lemieux, M.J. Deposit date: 2022-07-04 Release date: 2023-05-17 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.6 Å) Cite: SARS-CoV-2 M pro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals. Acs Cent.Sci., 9, 2023
7ZQZ	F61V Cytochrome c prime beta from Methylococcus capsulatus (Bath): NO complex Descriptor: Cytochrome c, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Adams, H.R, Hough, M.A. Deposit date: 2022-05-03 Release date: 2023-05-17 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.68 Å) Cite: A heme pocket aromatic quadrupole modulates gas binding to cytochrome c'-beta : Implications for NO sensors. J.Biol.Chem., 299, 2023
7ZSW	F32V Cytochrome c prime beta from Methylococcus capsulatus (Bath): NO Complex Descriptor: Cytochrome c, GLYCEROL, HEME C, ... Authors: Adams, H.R, Hough, M.A. Deposit date: 2022-05-09 Release date: 2023-05-17 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.94 Å) Cite: A heme pocket aromatic quadrupole modulates gas binding to cytochrome c'-beta : Implications for NO sensors. J.Biol.Chem., 299, 2023
7ZSX	F32V Cytochrome c prime beta from Methylococcus capsulatus (Bath): CO Complex Descriptor: CARBON MONOXIDE, Cytochrome c, GLYCEROL, ... Authors: Adams, H.R, Hough, M.A. Deposit date: 2022-05-09 Release date: 2023-05-17 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.77 Å) Cite: A heme pocket aromatic quadrupole modulates gas binding to cytochrome c'-beta : Implications for NO sensors. J.Biol.Chem., 299, 2023
7ZRX	F61V Cytochrome c prime beta from Methylococcus capsulatus (Bath) Chemically Reduced Ferrous State Descriptor: Cytochrome c, GLYCEROL, HEME C, ... Authors: Adams, H.R, Hough, M.A. Deposit date: 2022-05-05 Release date: 2023-05-17 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.04 Å) Cite: A heme pocket aromatic quadrupole modulates gas binding to cytochrome c'-beta : Implications for NO sensors. J.Biol.Chem., 299, 2023
7ZSV	F32V Cytochrome c prime beta from Methylococcus capsulatus (Bath) Chemically Reduced Ferrous Form Descriptor: Cytochrome c, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Adams, H.R, Hough, M.A. Deposit date: 2022-05-09 Release date: 2023-05-17 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.74 Å) Cite: A heme pocket aromatic quadrupole modulates gas binding to cytochrome c'-beta : Implications for NO sensors. J.Biol.Chem., 299, 2023
7ZRW	F61V Cytochrome c prime beta from Methylococcus capsulatus (Bath) Descriptor: Cytochrome c, GLYCEROL, HEME C, ... Authors: Adams, H.R, Hough, M.A. Deposit date: 2022-05-05 Release date: 2023-05-17 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.96 Å) Cite: A heme pocket aromatic quadrupole modulates gas binding to cytochrome c'-beta : Implications for NO sensors. J.Biol.Chem., 299, 2023
7ZS4	F32V Cytochrome c prime beta from Methylococcus capsulatus (Bath) Descriptor: Cytochrome c, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Adams, H.R, Hough, M.A. Deposit date: 2022-05-06 Release date: 2023-05-17 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.75 Å) Cite: A heme pocket aromatic quadrupole modulates gas binding to cytochrome c'-beta : Implications for NO sensors. J.Biol.Chem., 299, 2023
8J3N	Solution NMR structure of purS subunit of phosphoribosylformylglycinamidine synthase enzyme from Staphylococcus aureus Descriptor: Phosphoribosylformylglycinamidine synthase subunit PurS Authors: Wahab, A, Ashraf, F, Choudhary, M.I. Deposit date: 2023-04-17 Release date: 2023-05-17 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Solution NMR structure of purS subunit of phosphoribosylformylglycinamidine synthase enzyme from Staphylococcus aureus To Be Published
8BGR	FAD-independent Methylene-Tetrahydrofolate Reductase from Mycobacterium hassiacum Descriptor: Methylenetetrahydrofolate reductase Authors: Gehl, M, Ermler, U, Shima, S. Deposit date: 2022-10-28 Release date: 2023-05-10 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of FAD-independent methylene-tetrahydrofolate reductase from Mycobacterium hassiacum. Proteins, 91, 2023
8H3M	Conformation 1 of SARS-CoV-2 Omicron BA.1 Variant Spike protein complexed with MO1 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MO1 heavy chain, Spike glycoprotein Authors: Ishimaru, H, Nishimura, M, Sutandhio, S, Shigematsu, H, Kato, K, Hasegawa, N, Mori, Y. Deposit date: 2022-10-09 Release date: 2023-05-10 Last modified: 2023-08-02 Method: ELECTRON MICROSCOPY (2.48 Å) Cite: Identification and Analysis of Monoclonal Antibodies with Neutralizing Activity against Diverse SARS-CoV-2 Variants. J.Virol., 97, 2023
8H3N	Conformation 2 of SARS-CoV-2 Omicron BA.1 Variant Spike protein complexed with MO1 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MO1 heavy-chain, MO1 light chain, ... Authors: Ishimaru, H, Nishimura, M, Sutandhio, S, Shigematsu, H, Kato, K, Hasegawa, N, Mori, Y. Deposit date: 2022-10-09 Release date: 2023-05-10 Last modified: 2023-08-02 Method: ELECTRON MICROSCOPY (2.73 Å) Cite: Identification and Analysis of Monoclonal Antibodies with Neutralizing Activity against Diverse SARS-CoV-2 Variants. J.Virol., 97, 2023
8FG0	Crystal structure of the 3764 Fab in complex with the C-terminal PfCSP linker, PfCSP281-294. Descriptor: 3764 Fab Heavy chain, 3764 Fab Light chain, Circumsporozoite protein Authors: Burn Aschner, C, Julien, J.P. Deposit date: 2022-12-11 Release date: 2023-05-10 Last modified: 2023-06-14 Method: X-RAY DIFFRACTION (2.36 Å) Cite: Molecular and functional properties of human Plasmodium falciparum CSP C-terminus antibodies. Embo Mol Med, 15, 2023
7ZPS	Cytochrome c prime beta from Methylococcus capsulatus (Bath): NO complex Descriptor: Cytochrome c, GLYCEROL, HEME C, ... Authors: Adams, H.R, Hough, M.A. Deposit date: 2022-04-28 Release date: 2023-05-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.56 Å) Cite: A heme pocket aromatic quadrupole modulates gas binding to cytochrome c'-beta : Implications for NO sensors. J.Biol.Chem., 299, 2023
8A99	SARS Cov2 Spike in 1-up conformation complex with Fab47 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab47 (Heavy chain variable domain), ... Authors: Hallberg, B.M, Das, H. Deposit date: 2022-06-28 Release date: 2023-05-10 Last modified: 2023-09-27 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies. Immunity, 56, 2023
8OKL	Crystal structure of F2F-2020185-01X bound to the main protease (3CLpro/Mpro) of SARS-CoV-2. Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 3C-like proteinase nsp5, ... Authors: Costanzi, E, Demitri, N, Storici, P. Deposit date: 2023-03-28 Release date: 2023-05-03 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination. Eur.J.Med.Chem., 253, 2023
8OKM	Crystal structure of F2F-2020197-00X bound to the main protease (3CLpro/Mpro) of SARS-CoV-2. Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 3C-like proteinase nsp5, ... Authors: Costanzi, E, Demitri, N, Storici, P. Deposit date: 2023-03-28 Release date: 2023-05-03 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.66 Å) Cite: Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination. Eur.J.Med.Chem., 253, 2023
8OKN	Crystal structure of F2F-2020198-00X bound to the main protease (3CLpro/Mpro) of SARS-CoV-2. Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 3C-like proteinase nsp5, ... Authors: Costanzi, E, Demitri, N, Storici, P. Deposit date: 2023-03-28 Release date: 2023-05-03 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination. Eur.J.Med.Chem., 253, 2023
8OKK	Crystal structure of F2F-2020184-00X bound to the main protease (3CLpro/Mpro) of SARS-CoV-2. Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 3C-like proteinase nsp5, ... Authors: Costanzi, E, Demitri, N, Storici, P. Deposit date: 2023-03-28 Release date: 2023-05-03 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination. Eur.J.Med.Chem., 253, 2023
8DI3	Polymorphism in SARS-CoV-2 Nsp5 main protease reveals differences in cleavage of viral and host substrates Descriptor: 3C-like proteinase nsp5 Authors: Lu, J, Khan, M.B, Young, H.S, Lemieux, M.J. Deposit date: 2022-06-28 Release date: 2023-05-03 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.5 Å) Cite: SARS-CoV-2 M pro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals. Acs Cent.Sci., 9, 2023
8DKK	Polymorphism in SARS-CoV-2 Nsp5 main protease reveals differences in cleavage of viral and host substrates Descriptor: 3C-like proteinase nsp5 Authors: Lu, J, Khan, M.B, Young, H.S, Lemieux, M.J. Deposit date: 2022-07-05 Release date: 2023-05-03 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2 Å) Cite: SARS-CoV-2 M pro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals. Acs Cent.Sci., 9, 2023
8DMN	Polymorphism in SARS-CoV-2 Nsp5 main protease reveals differences in cleavage of viral and host substrates Descriptor: 3C-like proteinase nsp5 Authors: Lu, J, Khan, M.B, Young, H.S, Lemieux, M.J. Deposit date: 2022-07-08 Release date: 2023-05-03 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.3 Å) Cite: SARS-CoV-2 M pro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals. Acs Cent.Sci., 9, 2023
8DKH	Polymorphism in SARS-CoV-2 Nsp5 main protease reveals differences in cleavage of viral and host substrates Descriptor: 3C-like proteinase nsp5 Authors: Lu, J, Khan, M.B, Young, H.S, Lemieux, M.J. Deposit date: 2022-07-05 Release date: 2023-05-03 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.95 Å) Cite: SARS-CoV-2 M pro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals. Acs Cent.Sci., 9, 2023
8DKL	Polymorphism in SARS-CoV-2 Nsp5 main protease reveals differences in cleavage of viral and host substrates Descriptor: 3C-like proteinase nsp5 Authors: Lu, J, Khan, M.B, Young, H.S, Lemieux, M.J. Deposit date: 2022-07-05 Release date: 2023-05-03 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.9 Å) Cite: SARS-CoV-2 M pro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals. Acs Cent.Sci., 9, 2023
8DKJ	Polymorphism in SARS-CoV-2 Nsp5 main protease reveals differences in cleavage of viral and host substrates Descriptor: 3C-like proteinase nsp5 Authors: Lu, J, Khan, M.B, Young, H.S, Lemieux, M.J. Deposit date: 2022-07-05 Release date: 2023-05-03 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.11 Å) Cite: SARS-CoV-2 M pro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals. Acs Cent.Sci., 9, 2023

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