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7VRL
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BU of 7vrl by Molmil
Solution structure of Rbfox RRM bound to a non-cognate RNA
Descriptor: RNA (5'-R(*UP*GP*CP*AP*UP*AP*U)-3'), RNA binding protein fox-1 homolog 1
Authors:Yang, F, Varani, G.
Deposit date:2021-10-23
Release date:2022-10-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Two distinct binding modes provide the RNA-binding protein RbFox with extraordinary sequence specificity.
Nat Commun, 14, 2023
4A93
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BU of 4a93 by Molmil
RNA Polymerase II elongation complex containing a CPD Lesion
Descriptor: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*T*TTP*TP*TP*CP*C BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP*AP)-3', ...
Authors:Walmacq, C, Cheung, A.C.M, Kireeva, M.L, Lubkowska, L, Ye, C, Gotte, D, Strathern, J.N, Carell, T, Cramer, P, Kashlev, M.
Deposit date:2011-11-23
Release date:2012-03-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage.
Mol.Cell, 46, 2012
8BWT
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BU of 8bwt by Molmil
Structure of a symmetrical internal loop motif with three consecutive U:U mismatches from stem-loop 1 in the 3'-UTR of the SARS-CoV2 genomic RNA
Descriptor: RNA (26-MER)
Authors:Voegele, J, Duchardt-Ferner, E, Schwalbe, H, Woehnert, J.
Deposit date:2022-12-07
Release date:2023-08-30
Last modified:2024-07-03
Method:SOLUTION NMR
Cite:Structure of an internal loop motif with three consecutive U•U mismatches from stem-loop 1 in the 3'-UTR of the SARS-CoV-2 genomic RNA.
Nucleic Acids Res., 52, 2024
6GWK
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BU of 6gwk by Molmil
The crystal structure of Hfq from Caulobacter crescentus
Descriptor: RNA-binding protein Hfq
Authors:Santiago-Frangos, A, Frohlich, K.S, Jeliazkov, J.R, Gray, J.R, Luisi, B.F, Woodson, S.A, Hardwick, S.W.
Deposit date:2018-06-25
Release date:2019-05-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Caulobacter crescentusHfq structure reveals a conserved mechanism of RNA annealing regulation.
Proc.Natl.Acad.Sci.USA, 116, 2019
8ID2
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BU of 8id2 by Molmil
Crystal structure of the ubiquitin-like domain in the SF3A1 subunit of human U2 snRNP complexed with the stem-loop 4 of U1 snRNA
Descriptor: RNA (5'-R(*GP*GP*GP*GP*AP*CP*UP*GP*CP*GP*UP*UP*CP*GP*CP*GP*CP*UP*UP*UP*CP*CP*CP*C)-3'), Splicing factor 3A subunit 1
Authors:Terawaki, S, Nameki, N, Kuwasako, K.
Deposit date:2023-02-12
Release date:2023-05-17
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into recognition of SL4, the UUCG stem-loop, of human U1 snRNA by the ubiquitin-like domain, including the C-terminal tail in the SF3A1 subunit of U2 snRNP.
J.Biochem., 174, 2023
6F5P
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BU of 6f5p by Molmil
A mechanism for the activation of the influenza virus transcriptase
Descriptor: ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, DNA-directed RNA polymerase subunit, MAGNESIUM ION, ...
Authors:Serna Martin, I, Grimes, J.M.
Deposit date:2017-12-02
Release date:2018-09-19
Method:X-RAY DIFFRACTION (4.14 Å)
Cite:A Mechanism for the Activation of the Influenza Virus Transcriptase.
Mol. Cell, 70, 2018
6F5O
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BU of 6f5o by Molmil
A mechanism for the activation of the influenza virus transcriptase
Descriptor: 3' promoter vRNA, 5' promoter vRNA, Polymerase acidic protein, ...
Authors:Serna Martin, I, Grimes, J.M.
Deposit date:2017-12-02
Release date:2018-06-27
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:A Mechanism for the Activation of the Influenza Virus Transcriptase.
Mol. Cell, 70, 2018
4ILJ
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BU of 4ilj by Molmil
Crystal structure of an Prp8p RNaseH W1911A mutant protein
Descriptor: Pre-mRNA-splicing factor 8
Authors:Weber, G, Heroven, C, Santos, K.F, Wahl, M.C.
Deposit date:2012-12-31
Release date:2013-03-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.0001 Å)
Cite:Structural basis for dual roles of Aar2p in U5 snRNP assembly.
Genes Dev., 27, 2013
4IQM
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BU of 4iqm by Molmil
Crystal structure of the catalytic domain of human Pus1
Descriptor: tRNA pseudouridine synthase A, mitochondrial
Authors:Czudnochowski, N, Finer-Moore, J.S, Stroud, R.M.
Deposit date:2013-01-11
Release date:2013-06-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:In Human Pseudouridine Synthase 1 (hPus1), a C-Terminal Helical Insert Blocks tRNA from Binding in the Same Orientation as in the Pus1 Bacterial Homologue TruA, Consistent with Their Different Target Selectivities.
J.Mol.Biol., 425, 2013
4WFZ
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BU of 4wfz by Molmil
Coxsackievirus B3 3Dpol RNA Dependent RNA Polymerase - NaCl Crystal Form
Descriptor: RNA-directed RNA polymerase, SODIUM ION
Authors:Peersen, O.B, McDonald, S.M.
Deposit date:2014-09-17
Release date:2014-10-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.803 Å)
Cite:Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA Polymerases.
J.Virol., 89, 2015
6H45
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BU of 6h45 by Molmil
crystal structure of the human TGT catalytic subunit QTRT1 in complex with queuine
Descriptor: 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, BROMIDE ION, CHLORIDE ION, ...
Authors:Johannsson, S, Neumann, P, Ficner, R.
Deposit date:2018-07-20
Release date:2018-09-05
Last modified:2023-03-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the Human tRNA Guanine Transglycosylase Catalytic Subunit QTRT1.
Biomolecules, 8, 2018
3RW6
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BU of 3rw6 by Molmil
Structure of nuclear RNA export factor TAP bound to CTE RNA
Descriptor: Nuclear RNA export factor 1, constitutive transport element(CTE)of Mason-Pfizer monkey virus RNA
Authors:Teplova, M, Khin, N.W, Patel, D.J, Izaurralde, E.
Deposit date:2011-05-07
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP.
Nat.Struct.Mol.Biol., 18, 2011
8SP9
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BU of 8sp9 by Molmil
Crystal Structure of Coxsackievirus B3 (CVB3) Cloverleaf RNA with tRNA scaffold
Descriptor: tRNA scaffold,CVB3 Cloverleaf RNA
Authors:Gottipati, K, McNeme, S.C, Choi, K.H.
Deposit date:2023-05-02
Release date:2023-08-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Structural basis for cloverleaf RNA-initiated viral genome replication.
Nucleic Acids Res., 51, 2023
1BZ2
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BU of 1bz2 by Molmil
STABILIZATION OF THE ANTICODON STEM-LOOP OF TRNALYS,3 BY AN A+C BASE PAIR AND BY PSEUDOURIDINE, NMR, 1 STRUCTURE
Descriptor: TRNA
Authors:Durant, P.C, Davis, D.R.
Deposit date:1998-11-05
Release date:1999-04-27
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Stabilization of the anticodon stem-loop of tRNALys,3 by an A+-C base-pair and by pseudouridine.
J.Mol.Biol., 285, 1999
8UKU
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BU of 8uku by Molmil
RNA polymerase II elongation complex with Fapy-dG lesion with CMP added
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Hou, P, Oh, J, Wang, D.
Deposit date:2023-10-15
Release date:2024-04-24
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG.
J.Am.Chem.Soc., 146, 2024
8UKR
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BU of 8ukr by Molmil
RNA polymerase II elongation complex with Fapy-dG lesion soaking with ATP before chemistry
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Hou, P, Oh, J, Wang, D.
Deposit date:2023-10-15
Release date:2024-04-24
Method:X-RAY DIFFRACTION (3.78 Å)
Cite:Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG.
J.Am.Chem.Soc., 146, 2024
8UKS
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BU of 8uks by Molmil
RNA polymerase II elongation complex with Fapy-dG lesion soaking with CTP before chemistry
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Hou, P, Oh, J, Wang, D.
Deposit date:2023-10-15
Release date:2024-04-24
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG.
J.Am.Chem.Soc., 146, 2024
8UKT
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BU of 8ukt by Molmil
RNA polymerase II elongation complex with Fapy-dG lesion with AMP added
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Hou, P, Oh, J, Wang, D.
Deposit date:2023-10-15
Release date:2024-04-24
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG.
J.Am.Chem.Soc., 146, 2024
1BZT
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BU of 1bzt by Molmil
STABILIZATION OF THE ANTICODON STEM-LOOP OF TRNALYS,3 BY AN A+C BASE PAIR AND BY PSEUDOURIDINE, NMR, 1 STRUCTURE
Descriptor: TRNA
Authors:Durant, P.C, Davis, D.R.
Deposit date:1998-11-05
Release date:1999-04-27
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Stabilization of the anticodon stem-loop of tRNALys,3 by an A+-C base-pair and by pseudouridine.
J.Mol.Biol., 285, 1999
1BZU
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BU of 1bzu by Molmil
STABILIZATION OF THE ANTICODON STEM-LOOP OF TRNALYS, 3 BY AN A+C BASE PAIR AND BY PSEUDOURIDINE, NMR, 1 STRUCTURE
Descriptor: TRNA
Authors:Durant, P.C, Davis, D.R.
Deposit date:1998-11-05
Release date:1999-04-27
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Stabilization of the anticodon stem-loop of tRNALys,3 by an A+-C base-pair and by pseudouridine.
J.Mol.Biol., 285, 1999
1BZ3
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BU of 1bz3 by Molmil
STABILIZATION OF THE ANTICODON STEM-LOOP OF TRNALYS,3 BY AN A+C BASE PAIR AND BY PSEUDOURIDINE, NMR, 1 STRUCTURE
Descriptor: TRNA
Authors:Durant, P.C, Davis, D.R.
Deposit date:1998-11-05
Release date:1999-04-27
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Stabilization of the anticodon stem-loop of tRNALys,3 by an A+-C base-pair and by pseudouridine.
J.Mol.Biol., 285, 1999
7R2V
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BU of 7r2v by Molmil
Structure of nsp14 from SARS-CoV-2 in complex with SAH
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Proofreading exoribonuclease nsp14, ...
Authors:Czarna, A, Plewka, J, Kresik, L, Matsuda, A, Abdulkarim, K, Robinson, C, OByrne, S, Cunningham, F, Georgiou, I, Pachota, M, Popowicz, G.M, Wyatt, P.G, Dubin, G, Pyrc, K.
Deposit date:2022-02-06
Release date:2022-03-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity.
Structure, 30, 2022
7KW8
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BU of 7kw8 by Molmil
NMR Structure of a tRNA 2'-phosphotransferase from Runella slithyformis
Descriptor: tRNA 2'-phosphotransferase
Authors:Alphonse, S, Dantuluri, S, Banerjee, A, Shuman, S, Ghose, R.
Deposit date:2020-11-30
Release date:2021-10-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR solution structures of Runella slithyformis RNA 2'-phosphotransferase Tpt1 provide insights into NAD+ binding and specificity.
Nucleic Acids Res., 49, 2021
8UKQ
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BU of 8ukq by Molmil
RNA polymerase II elongation complex with Fapy-dG lesion in apo state
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Hou, P, Oh, J, Wang, D.
Deposit date:2023-10-15
Release date:2024-04-24
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG.
J.Am.Chem.Soc., 146, 2024
3B0U
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BU of 3b0u by Molmil
tRNA-dihydrouridine synthase from Thermus thermophilus in complex with tRNA fragment
Descriptor: FLAVIN MONONUCLEOTIDE, RNA (5'-R(*GP*GP*(H2U)P*A)-3'), tRNA-dihydrouridine synthase
Authors:Yu, F, Tanaka, Y, Yamashita, K, Nakamura, A, Yao, M, Tanaka, I.
Deposit date:2011-06-14
Release date:2011-12-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.948 Å)
Cite:Molecular basis of dihydrouridine formation on tRNA
Proc.Natl.Acad.Sci.USA, 108, 2011

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