8CR4
| |
8CR3
| |
5VT2
| Crystal structure of growth differentiation factor | Descriptor: | 1,2-ETHANEDIOL, Growth/differentiation factor 15 | Authors: | Min, X, Wang, Z. | Deposit date: | 2017-05-15 | Release date: | 2017-11-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys. Sci Transl Med, 9, 2017
|
|
5NB8
| Structure of vWC domain from CCN3 | Descriptor: | GLYCEROL, IMIDAZOLE, Protein NOV homolog | Authors: | Xu, E.-R, Hyvonen, M. | Deposit date: | 2017-03-01 | Release date: | 2017-06-14 | Last modified: | 2017-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural analyses of von Willebrand factor C domains of collagen 2A and CCN3 reveal an alternative mode of binding to bone morphogenetic protein-2. J. Biol. Chem., 292, 2017
|
|
5NIR
| Crystal structure of collagen 2A vWC domain | Descriptor: | 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Collagen alpha-1(II) chain, ... | Authors: | Fischer, G, Blythe, E, Hyvonen, M. | Deposit date: | 2017-03-27 | Release date: | 2017-06-14 | Last modified: | 2017-08-09 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structural analyses of von Willebrand factor C domains of collagen 2A and CCN3 reveal an alternative mode of binding to bone morphogenetic protein-2. J. Biol. Chem., 292, 2017
|
|
5DLQ
| Crystal structure of RanGTP-Exportin 4-eIF5A complex | Descriptor: | Eukaryotic translation initiation factor 5A-1, Exportin-4, GTP-binding nuclear protein Ran, ... | Authors: | Aksu, M, Trakhanov, S, Gorlich, D. | Deposit date: | 2015-09-07 | Release date: | 2016-06-22 | Last modified: | 2016-06-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure of the exportin Xpo4 in complex with RanGTP and the hypusine-containing translation factor eIF5A. Nat Commun, 7, 2016
|
|
8HIA
| |
8HGA
| |
8PKJ
| Cryo-EM structure of the nucleosome containing Nr5a2 motif at SHL+5.5 | Descriptor: | DNA, Histone H2A, Histone H2B, ... | Authors: | Kobayashi, W, Sappler, A, Bollschweiler, D, Kummecke, M, Basquin, J, Arslantas, E, Ruangroengkulrith, S, Hornberger, R, Duderstadt, K, Tachibana, K. | Deposit date: | 2023-06-26 | Release date: | 2024-02-28 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Nucleosome-bound NR5A2 structure reveals pioneer factor mechanism by DNA minor groove anchor competition. Nat.Struct.Mol.Biol., 31, 2024
|
|
5A3U
| HIF prolyl hydroxylase 2 (PHD2/EGLN1) in complex with 6-(5-oxo-4-(1H- 1,2,3-triazol-1-yl)-2,5-dihydro-1H-pyrazol-1-yl)nicotinic acid | Descriptor: | 6-(5-oxo-4-(1H-1,2,3-triazol-1-yl)-2,5-dihydro-1H-pyrazol-1-yl)nicotinic acid, EGL NINE HOMOLOG 1, MANGANESE (II) ION | Authors: | Chowdhury, R, Gomez-Perez, V, Schofield, C.J. | Deposit date: | 2015-06-03 | Release date: | 2015-06-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain. Plos One, 10, 2015
|
|
5L0S
| human POGLUT1 in complex with Factor VII EGF1 and UDP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | Authors: | Li, Z, Rini, J.M. | Deposit date: | 2016-07-28 | Release date: | 2017-08-09 | Last modified: | 2021-03-24 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural basis of Notch O-glucosylation and O-xylosylation by mammalian protein-O-glucosyltransferase 1 (POGLUT1). Nat Commun, 8, 2017
|
|
1ZDU
| The Crystal Structure of Human Liver Receptor Homologue-1 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Nuclear receptor coactivator 2, Orphan nuclear receptor NR5A2, ... | Authors: | Wang, W, Zhang, C, Marimuthu, A, Krupka, H.I, Tabrizizad, M, Shelloe, R, Mehra, U, Eng, K, Nguyen, H, Settachatgul, C, Powell, B, Milburn, M.V, West, B.L. | Deposit date: | 2005-04-14 | Release date: | 2005-05-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1 Proc.Natl.Acad.Sci.USA, 102, 2005
|
|
1VR1
| Specifity for Plasminogen Activator Inhibitor-1 | Descriptor: | Hirudin, thrombin | Authors: | Dekker, R.J, Eichinger, A, Stoop, A.A, Bode, W, Pannekoek, H, Horrevoets, A.J.G. | Deposit date: | 1998-12-11 | Release date: | 1999-12-29 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The variable region-1 from tissue-type plasminogen activator confers specificity for plasminogen activator inhibitor-1 to thrombin by facilitating catalysis: release of a kinetic block by a heterologous protein surface loop J.Mol.Biol., 293, 1999
|
|
1XF0
| Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (AKR1C3) complexed with delta4-androstene-3,17-dione and NADP | Descriptor: | 4-ANDROSTENE-3-17-DIONE, ACETATE ION, Aldo-keto reductase family 1 member C3, ... | Authors: | Qiu, W, Zhou, M, Labrie, F, Lin, S.-X. | Deposit date: | 2004-09-13 | Release date: | 2004-10-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues Mol.Endocrinol., 18, 2004
|
|
1U3Y
| Crystal structure of ILAC mutant of dimerisation domain of NF-kB p50 transcription factor | Descriptor: | Nuclear factor NF-kappa-B p105 subunit | Authors: | Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. | Deposit date: | 2004-07-22 | Release date: | 2004-08-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding Structure, 12, 2004
|
|
1U42
| Crystal structure of MLAM mutant of dimerisation domain of NF-kB p50 transcription factor | Descriptor: | Nuclear factor NF-kappa-B p105 subunit | Authors: | Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. | Deposit date: | 2004-07-23 | Release date: | 2004-08-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.699 Å) | Cite: | Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding Structure, 12, 2004
|
|
1U41
| Crystal structure of YLGV mutant of dimerisation domain of NF-kB p50 transcription factor | Descriptor: | Nuclear factor NF-kappa-B p105 subunit | Authors: | Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. | Deposit date: | 2004-07-23 | Release date: | 2004-08-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.202 Å) | Cite: | Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding Structure, 12, 2004
|
|
1U3Z
| Crystal structure of MLAC mutant of dimerisation domain of NF-kB p50 transcription factor | Descriptor: | Nuclear factor NF-kappa-B p105 subunit | Authors: | Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. | Deposit date: | 2004-07-23 | Release date: | 2004-08-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding Structure, 12, 2004
|
|
1U3J
| Crystal structure of MLAV mutant of dimerisation domain of NF-kB p50 transcription factor | Descriptor: | Nuclear factor NF-kappa-B p105 subunit | Authors: | Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. | Deposit date: | 2004-07-22 | Release date: | 2004-08-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding Structure, 12, 2004
|
|
2XB1
| Crystal structure of the human Pygo2 PHD finger in complex with the B9L HD1 domain | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, PYGOPUS HOMOLOG 2, ... | Authors: | Miller, T.C, Rutherford, T.J, Johnson, C.M, Fiedler, M, Bienz, M. | Deposit date: | 2010-04-01 | Release date: | 2010-07-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Allosteric Remodeling of the Histone H3 Binding Pocket in the Pygo2 Phd Finger Triggered by its Binding to the B9L/Bcl9 Co-Factor. J.Mol.Biol., 401, 2010
|
|
4M7K
| Crystal structure of anti-tissue factor antibody 10H10 | Descriptor: | 10H10 heavy chain, 10H10 light chain, ACETATE ION, ... | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | Deposit date: | 2013-08-12 | Release date: | 2014-03-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Antibody modeling assessment II. Structures and models. Proteins, 82, 2014
|
|
3MLP
| Early B-cell Factor 1 (Ebf1) bound to DNA | Descriptor: | CITRIC ACID, DNA (5'-D(*CP*TP*TP*TP*AP*TP*TP*CP*CP*CP*AP*TP*GP*GP*GP*AP*AP*TP*AP*AP*AP*G)-3'), Transcription factor COE1, ... | Authors: | Treiber, N, Treiber, T, Zocher, G, Grosschedl, R. | Deposit date: | 2010-04-17 | Release date: | 2010-12-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins Genes Dev., 24, 2010
|
|
4CH0
| RRM domain from C. elegans SUP-12 | Descriptor: | PROTEIN SUP-12, ISOFORM B | Authors: | Amrane, S, Mackereth, C.D. | Deposit date: | 2013-11-27 | Release date: | 2014-09-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Backbone-Independent Nucleic Acid Binding by Splicing Factor Sup-12 Reveals Key Aspects of Molecular Recognition Nat.Commun., 5, 2014
|
|
4CIO
| |
4CH1
| |