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1U1O	Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(DI)G); A Human Telomeric Repeat Containing Inosine Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*(OIP)*G)-3', Heterogeneous nuclear ribonucleoprotein A1 Authors: Myers, J.C, Shamoo, Y. Deposit date: 2004-07-15 Release date: 2004-09-21 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2 Å) Cite: Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM). J.Mol.Biol., 342, 2004
1U1M	Crystal Structure of UP1 Complexed With d(TTAGGGTTA 7GU GG); A Human Telomeric Repeat Containing 7-deaza-guanine Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*(7GU)P*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1 Authors: Myers, J.C, Shamoo, Y. Deposit date: 2004-07-15 Release date: 2004-09-21 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2 Å) Cite: Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM). J.Mol.Biol., 342, 2004
1U1R	Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(2PR)G); A Human Telomeric Repeat Containing 2-aminopurine Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*(2PR)P*G)-3', Heterogeneous nuclear ribonucleoprotein A1 Authors: Myers, J.C, Shamoo, Y. Deposit date: 2004-07-15 Release date: 2004-09-21 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM). J.Mol.Biol., 342, 2004
1WF2	Solution structure of RRM domain in HNRPC protein Descriptor: Heterogeneous nuclear ribonucleoproteins C1/C2 Authors: He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2004-05-25 Release date: 2004-11-25 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of RRM domain in HNRPC protein To be Published
1UP1	UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1 Descriptor: HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 Authors: Xu, R.-M, Jokhan, L, Cheng, X, Mayeda, A, Krainer, A.R. Deposit date: 1997-03-12 Release date: 1997-09-17 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of human UP1, the domain of hnRNP A1 that contains two RNA-recognition motifs. Structure, 5, 1997
8QPK	Cryo-EM Structure of Pre-B+5'ss Complex (core part) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. Deposit date: 2023-10-02 Release date: 2024-05-22 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
1U1K	Crystal Structure of UP1 Complexed With d(TTAGGGTT 7DA GGG); A Human Telomeric Repeat Containing 7-deaza-adenine Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*(7DA)P*GP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1 Authors: Myers, J.C, Shamoo, Y. Deposit date: 2004-07-15 Release date: 2004-09-21 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2 Å) Cite: Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM). J.Mol.Biol., 342, 2004
1U1N	Crystal Structure of UP1 Complexed With d(TTAGGGTTA (PRN)GG); A Human Telomeric Repeat Containing Nebularine Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*(PRN)P*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1 Authors: Myers, J.C, Shamoo, Y. Deposit date: 2004-07-15 Release date: 2004-09-21 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM). J.Mol.Biol., 342, 2004
1X8Y	Human lamin coil 2B Descriptor: Lamin A/C Authors: Strelkov, S.V, Schumacher, J, Burkhard, P, Aebi, U, Herrmann, H. Deposit date: 2004-08-19 Release date: 2004-11-16 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of the human lamin A coil 2B dimer: implications for the head-to-tail association of nuclear lamins J.Mol.Biol., 343, 2004
9ASP	Human Drosha and DGCR8 in complex with Pri-let-7a1 Descriptor: CALCIUM ION, Isoform 4 of Drosha, Microprocessor complex subunit DGCR8, ... Authors: Garg, A, Joshua-Tor, L. Deposit date: 2024-02-26 Release date: 2024-09-04 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: RNAi_protein_a1 To Be Published
9ASN	Human Drosha and DGCR8 in complex with Pri-miR-98 Descriptor: CALCIUM ION, Isoform 4 of Drosha, Microprocessor complex subunit DGCR8, ... Authors: Garg, A, Joshua-Tor, L. Deposit date: 2024-02-26 Release date: 2024-09-04 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: RNAi_protein_98 To Be Published
9F4R	UP1 in complex with Z802821712 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, N-ethyl-6-methylpyridazin-3-amine Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4M	UP1 in complex with Z1401276297 Descriptor: (5~{R})-7-pyrazin-2-yl-2-oxa-7-azaspiro[4.4]nonane, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.39 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F7F	UP1 in complex with Z1491353358 Descriptor: (3S)-1-(phenylsulfonyl)pyrrolidin-3-amine, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-05-03 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F1S	Structure of UP1 S4ES6E phosphomimetic mutant Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-20 Release date: 2024-05-01 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structure of UP1 S4ES6E phosphomimetic mutant To Be Published
9F4L	UP1 in complex with Z104584152 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, N,N-dimethyl-N~2~-phenylglycinamide Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9ASM	Human Drosha and DGCR8 in complex with Pri-let-7f1 Descriptor: CALCIUM ION, Isoform 4 of Drosha, Microprocessor complex subunit DGCR8, ... Authors: Garg, A, Joshua-Tor, L. Deposit date: 2024-02-26 Release date: 2024-09-04 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: RNAi_protein_f1 To Be Published
9F7H	UP1 in complex with Z45617795 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, N-(2-phenylethyl)methanesulfonamide Authors: Dunnett, L, Prischi, F. Deposit date: 2024-05-03 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4D	UP1 in complex with Z1203107138 Descriptor: 1-ethyl-N-[(4-fluorophenyl)methyl]-1H-pyrazole-4-carboxamide, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-27 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4W	UP1 in complex with Z54508609 Descriptor: 1-{[4-(propan-2-yl)phenyl]methyl}piperidin-4-ol, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4P	UP1 in complex with Z1217960891 Descriptor: (3S)-3-(3-fluorophenoxy)-1-methylpyrrolidin-2-one, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F5D	UP1 in complex with Z641230552 Descriptor: 5-[(phenylmethyl)amino]-1~{H}-pyrimidine-2,4-dione, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4Z	UP1 in complex with Z57040482 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, N-(2-hydroxyphenyl)acetamide Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F55	UP1 in complex with Z235361315 Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, ~{N}-(3-azanyl-2-methyl-phenyl)propanamide Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9F4F	UP1 in complex with Z86417414 Descriptor: 2-fluoranyl-~{N}-(1,3,4-thiadiazol-2-yl)benzamide, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-27 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published

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