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471D
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BU of 471d by Molmil
CRYSTAL STRUCTURE AND IMPROVED ANTISENSE PROPERTIES OF 2'-O-(2-METHOXYETHYL)-RNA
Descriptor: MAGNESIUM ION, RNA (5'-R(*(C43)P*(G48)P*(C43)P*(G48)P*(A44)P*(A44)P*(U36)P*(U36)P*(C43)P*(G48)P*(C43)P*(G48))-3')
Authors:Teplova, M, Minasov, G, Tereshko, V, Inamati, G, Cook, P.D, Egli, M.
Deposit date:1999-04-29
Release date:1999-05-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure and improved antisense properties of 2'-O-(2-methoxyethyl)-RNA.
Nat.Struct.Biol., 6, 1999
5SB8
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BU of 5sb8 by Molmil
Tubulin-maytansinoid-3-complex
Descriptor: (1S,2R,3S,5S,6S,16E,18E,20R)-11-chloro-6-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18,21-hexaene-8,23-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Marzullo, P, Boiarska, Z, Perez-Pena, H, Abel, A.-C, Alvarez-Bernad, B, Lucena-Agell, D, Vasile, F, Sironi, M, Steinmetz, M.O, Prota, A.E, Diaz, J.F, Pieraccini, S, Passarella, D.
Deposit date:2021-07-20
Release date:2021-12-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders.
Chemistry, 28, 2022
5SBD
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BU of 5sbd by Molmil
Tubulin-maytansinoid-5b-complex
Descriptor: (1S,2R,3S,5S,6S,16E,18E,20R)-11-chloro-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18,21(25)-hexaen-6-yl acetate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Marzullo, P, Boiarska, Z, Perez-Pena, H, Abel, A.-C, Alvarez-Bernad, B, Lucena-Agell, D, Vasile, F, Sironi, M, Steinmetz, M.O, Prota, A.E, Diaz, J.F, Pieraccini, S, Passarella, D.
Deposit date:2021-07-20
Release date:2021-12-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders.
Chemistry, 28, 2022
5SBA
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BU of 5sba by Molmil
Tubulin-maytansinoid-4b-complex
Descriptor: (1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl acetate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Marzullo, P, Boiarska, Z, Perez-Pena, H, Abel, A.-C, Alvarez-Bernad, B, Lucena-Agell, D, Vasile, F, Sironi, M, Steinmetz, M.O, Prota, A.E, Diaz, J.F, Pieraccini, S, Passarella, D.
Deposit date:2021-07-20
Release date:2021-12-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders.
Chemistry, 28, 2022
5SBE
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BU of 5sbe by Molmil
Tubulin-maytansinoid-5c-complex
Descriptor: (1S,2R,3S,5S,6S,16E,18E,20R)-11-chloro-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18,21-hexaen-6-yl hept-6-ynoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Marzullo, P, Boiarska, Z, Perez-Pena, H, Abel, A.-C, Alvarez-Bernad, B, Lucena-Agell, D, Vasile, F, Sironi, M, Steinmetz, M.O, Prota, A.E, Diaz, J.F, Pieraccini, S, Passarella, D.
Deposit date:2021-07-20
Release date:2021-12-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders.
Chemistry, 28, 2022
5SBB
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BU of 5sbb by Molmil
Tubulin-maytansinoid-4c-complex
Descriptor: (1R,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl heptanoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Marzullo, P, Boiarska, Z, Perez-Pena, H, Abel, A.-C, Alvarez-Bernad, B, Lucena-Agell, D, Vasile, F, Sironi, M, Steinmetz, M.O, Prota, A.E, Diaz, J.F, Pieraccini, S, Passarella, D.
Deposit date:2021-07-20
Release date:2021-12-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders.
Chemistry, 28, 2022
5SBC
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BU of 5sbc by Molmil
Tubulin-maytansinoid-5a-complex
Descriptor: (1S,2R,3S,5S,6S,16E,18E,20R)-11-chloro-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18,21-hexaen-6-yl phenylacetate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Marzullo, P, Boiarska, Z, Perez-Pena, H, Abel, A.-C, Alvarez-Bernad, B, Lucena-Agell, D, Vasile, F, Sironi, M, Steinmetz, M.O, Prota, A.E, Diaz, J.F, Pieraccini, S, Passarella, D.
Deposit date:2021-07-20
Release date:2021-12-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders.
Chemistry, 28, 2022
5SB9
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BU of 5sb9 by Molmil
Tubulin-maytansinoid-4a-complex
Descriptor: (1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl phenylacetate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Marzullo, P, Boiarska, Z, Perez-Pena, H, Abel, A.-C, Alvarez-Bernad, B, Lucena-Agell, D, Vasile, F, Sironi, M, Steinmetz, M.O, Prota, A.E, Diaz, J.F, Pieraccini, S, Passarella, D.
Deposit date:2021-07-20
Release date:2021-12-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders.
Chemistry, 28, 2022
6H9X
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BU of 6h9x by Molmil
Klebsiella pneumoniae Seryl-tRNA Synthetase in Complex with the Intermediate Analog 5'-O-(N-(L-Seryl)-Sulfamoyl)Adenosine
Descriptor: 1,2-ETHANEDIOL, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, CALCIUM ION, ...
Authors:Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D.
Deposit date:2018-08-06
Release date:2019-05-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Acylated sulfonamide adenosines as potent inhibitors of the adenylate-forming enzyme superfamily.
Eur.J.Med.Chem., 174, 2019
2P89
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BU of 2p89 by Molmil
Solution structure of the 3' pseudouridyation pocket of U65 snoRNA with bound substrate
Descriptor: 28S rRNA, U65 H/ACA snoRNA
Authors:Wu, H, Feigon, J.
Deposit date:2007-03-22
Release date:2007-04-03
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:H/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modification.
Proc.Natl.Acad.Sci.Usa, 104, 2007
1BJ2
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BU of 1bj2 by Molmil
RNA LOOP-LOOP COMPLEX: THE COLE1 INVERTED LOOP SEQUENCE, NMR, 8 STRUCTURES
Descriptor: RNA (5'-R(*GP*CP*AP*CP*CP*GP*AP*AP*CP*CP*AP*UP*CP*CP*GP*GP*UP*GP*C)-3'), RNA (5'-R(*GP*GP*CP*AP*AP*CP*GP*GP*AP*UP*GP*GP*UP*UP*CP*GP*UP*UP*GP*CP*C)-3')
Authors:Lee, A.J, Crothers, D.M.
Deposit date:1998-07-02
Release date:1999-02-02
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The solution structure of an RNA loop-loop complex: the ColE1 inverted loop sequence.
Structure, 6, 1998
1ZIF
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BU of 1zif by Molmil
GAAA RNA TETRALOOP, NMR, 10 STRUCTURES
Descriptor: RNA (5'-R(*GP*GP*GP*CP*GP*AP*AP*AP*GP*CP*CP*U)-3')
Authors:Jucker, F.M, Heus, H.A, Yip, P.F, Moors, E, Pardi, A.
Deposit date:1996-07-27
Release date:1997-03-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A network of heterogeneous hydrogen bonds in GNRA tetraloops.
J.Mol.Biol., 264, 1996
1ZIG
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BU of 1zig by Molmil
GAGA RNA TETRALOOP, NMR, 10 STRUCTURES
Descriptor: RNA (5'-R(*GP*GP*GP*CP*GP*AP*GP*AP*GP*CP*CP*U)-3')
Authors:Jucker, F.M, Heus, H.A, Yip, P.F, Moors, E, Pardi, A.
Deposit date:1996-07-27
Release date:1997-03-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A network of heterogeneous hydrogen bonds in GNRA tetraloops.
J.Mol.Biol., 264, 1996
1ZIH
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BU of 1zih by Molmil
GCAA RNA TETRALOOP, NMR, 10 STRUCTURES
Descriptor: RNA (5'-R(*GP*GP*GP*CP*GP*CP*AP*AP*GP*CP*CP*U)-3')
Authors:Jucker, F.M, Heus, H.A, Yip, P.F, Moors, E, Pardi, A.
Deposit date:1996-07-27
Release date:1997-03-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A network of heterogeneous hydrogen bonds in GNRA tetraloops.
J.Mol.Biol., 264, 1996
3X1L
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BU of 3x1l by Molmil
Crystal Structure of the CRISPR-Cas RNA Silencing Cmr Complex Bound to a Target Analog
Descriptor: CRISPR system Cmr subunit Cmr2, CRISPR system Cmr subunit Cmr3, CRISPR system Cmr subunit Cmr5, ...
Authors:Osawa, T, Numata, T.
Deposit date:2014-11-20
Release date:2015-05-13
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.096 Å)
Cite:Crystal structure of the CRISPR-Cas RNA silencing Cmr complex bound to a target analog.
Mol.Cell, 58, 2015
2RQJ
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BU of 2rqj by Molmil
Quadruplex structure of an RNA aptamer against bovine prion protein
Descriptor: RNA (5'-R(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3')
Authors:Katahira, M, Mashima, T, Matsugami, A, Nishikawa, F, Nishikawa, S.
Deposit date:2009-07-18
Release date:2009-11-17
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Unique quadruplex structure and interaction of an RNA aptamer against bovine prion protein
Nucleic Acids Res., 37, 2009
1YMO
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BU of 1ymo by Molmil
Solution structure of the P2b-P3 pseudoknot from human telomerase RNA
Descriptor: Telomerase RNA P2b-P3 pseudoknot
Authors:Theimer, C.A, Blois, C.A, Feigon, J.
Deposit date:2005-01-21
Release date:2005-03-15
Last modified:2023-11-29
Method:SOLUTION NMR
Cite:Structure of the human telomerase RNA pseudoknot reveals conserved tertiary interactions essential for function
Mol.Cell, 17, 2005
4AL5
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BU of 4al5 by Molmil
Crystal structure of the Csy4-crRNA product complex
Descriptor: 5'-R(*UP*UP*CP*AP*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP *GP*GP*CP*AP*GP*C)-3', CSY4 ENDORIBONUCLEASE, GLYCEROL
Authors:Haurwitz, R.E, Sternberg, S.H, Doudna, J.A.
Deposit date:2012-03-02
Release date:2012-06-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Csy4 Relies on an Unusual Catalytic Dyad to Position and Cleave Crispr RNA.
Embo J., 31, 2012
8AXP
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BU of 8axp by Molmil
Neisseria gonorrhoeae peptidyl-tRNA hydrolase complexed with an XChem hit.
Descriptor: N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]acetamide, Peptidyl-tRNA hydrolase, SULFATE ION
Authors:Roe, S.M, Fearon, D.
Deposit date:2022-08-31
Release date:2022-11-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Synthesis of a Thiazole Library via an Iridium-Catalyzed Sulfur Ylide Insertion Reaction.
Org.Lett., 24, 2022
1XJR
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BU of 1xjr by Molmil
The Structure of a Rigorously Conserved RNA Element Within the SARS Virus Genome
Descriptor: MAGNESIUM ION, s2m RNA
Authors:Robertson, M.P, Igel, H, Baertsch, R, Haussler, D, Ares Jr, M, Scott, W.G.
Deposit date:2004-09-24
Release date:2005-02-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structure of a rigorously conserved RNA element within the SARS virus genome
Plos Biol., 3, 2005
6BMD
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BU of 6bmd by Molmil
RNA hairpin containing GpppG-oligo to mimic intermediate formed by activated monomer and activated downstream helper
Descriptor: RNA (5'-D(*(GP3))-R(P*CP*AP*CP*CP*UP*CP*A)-3'), RNA (5'-R(P*GP*AP*GP*GP*UP*GP*(LCC)P*(LCC)P*GP*AP*GP*CP*GP*CP*GP*AP*AP*AP*GP*CP*GP*CP*UP*C)-3')
Authors:Zhang, W, Szostak, J.W.
Deposit date:2017-11-14
Release date:2018-02-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
3WNC
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BU of 3wnc by Molmil
Crystal structure of EF-Pyl in complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein translation elongation factor 1A
Authors:Yanagisawa, T, Ishii, R, Fukunaga, R, Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2013-12-08
Release date:2014-12-10
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A SelB/EF-Tu/aIF2 gamma-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.).
J. Struct. Funct. Genomics, 16, 2015
3WNB
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BU of 3wnb by Molmil
Crystal structure of EF-Pyl in complex with GMPPNP
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein translation elongation factor 1A
Authors:Yanagisawa, T, Ishii, R, Fukunaga, R, Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2013-12-08
Release date:2014-12-10
Last modified:2020-05-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A SelB/EF-Tu/aIF2 gamma-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.).
J. Struct. Funct. Genomics, 16, 2015
3WND
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BU of 3wnd by Molmil
Crystal structure of EF-Pyl
Descriptor: CITRIC ACID, Protein translation elongation factor 1A
Authors:Yanagisawa, T, Ishii, R, Fukunaga, R, Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2013-12-08
Release date:2014-12-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A SelB/EF-Tu/aIF2 gamma-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.).
J. Struct. Funct. Genomics, 16, 2015
1AB6
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BU of 1ab6 by Molmil
STRUCTURE OF CHEY MUTANT F14N, V86T
Descriptor: CHEMOTAXIS PROTEIN CHEY
Authors:Wilcock, D, Pisabarro, M.T, Lopez-Hernandez, E, Serranno, L, Coll, M.
Deposit date:1997-02-04
Release date:1998-02-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure analysis of two CheY mutants: importance of the hydrogen-bond contribution to protein stability.
Acta Crystallogr.,Sect.D, 54, 1998

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